Basic Information

Gene Symbol
-
Assembly
GCA_935421255.1
Location
CAKXYX010000534.1:2516538-2517854[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0032 0.37 14.8 0.8 1 23 19 42 19 42 0.97
2 13 0.72 84 7.4 7.6 2 23 81 103 80 103 0.95
3 13 0.098 11 10.1 4.5 1 23 109 132 109 132 0.97
4 13 0.0025 0.29 15.1 2.8 1 23 138 161 138 161 0.98
5 13 1.5 1.7e+02 6.4 0.1 6 23 172 189 170 189 0.83
6 13 0.00017 0.02 18.7 1.3 1 23 195 218 195 218 0.98
7 13 0.00023 0.027 18.3 2.2 1 23 224 247 224 247 0.98
8 13 0.0003 0.035 18.0 1.9 1 21 253 273 253 274 0.96
9 13 0.0013 0.16 15.9 1.9 1 23 281 304 281 304 0.98
10 13 0.00026 0.03 18.2 1.3 1 23 310 333 310 333 0.98
11 13 0.0013 0.15 16.0 2.9 1 23 339 362 339 362 0.97
12 13 0.0047 0.54 14.2 2.8 1 23 368 391 368 391 0.98
13 13 3.9e-05 0.0046 20.8 2.1 1 23 397 420 397 420 0.98

Sequence Information

Coding Sequence
ATGTACAGAGCCGACTACAGGCACCATGTTAGCGAGCATTACCAGGTGAAAATGTACAAGTGTGGAATTTGTCGCAGAAGATACAATGCGAGGGAATCTCTCAAGACGCACTTGGAAAAAATTCATGCCGACAGTGAAGGAGAAGATGTCCAAAACAACTCTACGTGTGACTATTTCAAAGCTAATATTGAAAATATGAAAGAGAGATCTACACACTCACATGATGGCGAGAGGCAATGTCCATGCCCGAAATGCGAACTTCAAACAAGGAACAAATGTCATTTCAAATCACATATAAAGATAAAACATCCGAATAGAGGAAAATATAAGTGCGCACATTGCGAGTTTAAGACATATTACAGGTCTTATTTAGAAGTGCACACGAAAATGAAACATCTCATAGAAAGTTATTATAAATGCAGGGAGTGTGAATACAAGACAAATTATAAGTCAAAACTAGAACTACACATAAAAACAAAACATTTTCAAGAAAATAATTATAAATGGGCAGAGTGTGAATATAAAACAAATAAGTCAAATTTAAAAGCACACATAGTAATAAAACATCTTAAAATTAGCGCTTATAAATGCGCAGAATGTGAATATGAGACAAATAATAAGTCAAGTTTAGAAAGACATCTAAAGAGGAGACACCTTAAAATATACGATCATAAATGCGGAGAATGTGAATACAAGACAAATGACAAGTCAGACTTAGTAAGACACATAAAAACAAAACATCTTAAAGAACACGATTATAAATGCGCAGACTGTGAGTACAAGACAAACAATAAATCACATTTAAAGAAACACCTAAAGATAAAATATAAAAATTGCGACCATAAATGCGCAGAATGTGATTACATGACAAATACGGAGTCACGTTTAAAAGCACACATAAAGACCAAACATCTTAGCATAAGCGATTATAAATGCACAGAGTGTGAATATGAGACAAATTATACGTCAAATTTAAAGGCACACATAAAAATGAAACATCTTAAAGTATGCGATTATAAATGCGCAGAGTGTGAATACGAAACAAATTATAAGTCACATTTAGAAAGACACCTAAAGAACAGGCACCGTAAAATATACGATCACAAATGCGCAGAATGTGAATATAAGACAAATGAAAAGTCATACTTAGTAAGACACATAAAGACGAAACATCGTAATATACACGATTATAAATGCACAGAGTGTGAATACGAGACAAGTAATAAGTCAAGTTTAGAAAGACACCTAAAGCGAAAACACCTTGAATTATACGATCATAAATGCGCAGATTGTGAATATAAGACAAATGAAAAGTAA
Protein Sequence
MYRADYRHHVSEHYQVKMYKCGICRRRYNARESLKTHLEKIHADSEGEDVQNNSTCDYFKANIENMKERSTHSHDGERQCPCPKCELQTRNKCHFKSHIKIKHPNRGKYKCAHCEFKTYYRSYLEVHTKMKHLIESYYKCRECEYKTNYKSKLELHIKTKHFQENNYKWAECEYKTNKSNLKAHIVIKHLKISAYKCAECEYETNNKSSLERHLKRRHLKIYDHKCGECEYKTNDKSDLVRHIKTKHLKEHDYKCADCEYKTNNKSHLKKHLKIKYKNCDHKCAECDYMTNTESRLKAHIKTKHLSISDYKCTECEYETNYTSNLKAHIKMKHLKVCDYKCAECEYETNYKSHLERHLKNRHRKIYDHKCAECEYKTNEKSYLVRHIKTKHRNIHDYKCTECEYETSNKSSLERHLKRKHLELYDHKCADCEYKTNEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-