Basic Information

Gene Symbol
-
Assembly
GCA_935421255.1
Location
CAKXYX010000797.1:257035-258681[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00084 0.097 16.6 2.0 1 23 19 42 19 42 0.97
2 16 0.03 3.5 11.7 3.9 1 23 80 103 80 103 0.97
3 16 0.7 82 7.4 1.5 5 23 110 129 108 129 0.93
4 16 0.031 3.6 11.6 2.9 1 23 135 158 135 158 0.96
5 16 0.27 31 8.7 1.2 1 23 164 187 164 187 0.98
6 16 0.0015 0.18 15.8 3.0 1 23 193 216 193 216 0.96
7 16 0.0032 0.37 14.8 2.0 1 23 222 245 222 245 0.98
8 16 0.047 5.5 11.1 1.7 1 23 251 274 251 274 0.98
9 16 0.0022 0.26 15.3 2.2 1 23 280 303 280 303 0.98
10 16 0.0023 0.26 15.2 3.0 1 23 309 332 309 332 0.96
11 16 0.0013 0.16 15.9 2.2 1 23 367 390 367 390 0.98
12 16 2.9e-05 0.0034 21.2 3.0 1 23 398 421 398 421 0.98
13 16 0.0068 0.8 13.7 2.6 1 23 427 450 427 450 0.96
14 16 0.062 7.2 10.7 2.3 1 23 456 479 456 479 0.95
15 16 0.00047 0.055 17.4 2.2 1 23 485 508 485 508 0.98
16 16 0.056 6.5 10.8 2.3 1 23 514 537 514 537 0.96

Sequence Information

Coding Sequence
ATGTACAACGCCGACTTCAGAGATCACATTAACGAGCATTACGAGGTGAAAATGTATAAATGCGGAATTTGTCACAGAAGATACAAGGCGAAAGAATCTCTTAAGGCGCACGTGTTAAAAAATCATGTTAATAATGAAGGAAGAGGTATCCAAGCAAATATTAAAAATATAGGAGAGAGATCTCCACATTGTCGTTCAAAATCGCTTATAAAAATAAACCATATGAACAGAGACAAATATAAGTGCGCAAATTGCGAGTTTAAGACATATTACAGAAGTCATTTAGAAAGGCACGTGAAAATAAAGCATCTAAAGCAAGAGGAATATAAATGCGCGTACAAGACAAACCACAAGTCATATTTAAACAACCACATAAAATCAAAACATTGTAAAGAAAACTATTTTAAGTGCATGAGGTGTGAATTTAAGACAAACTACAAGTCAAGTTTAGTAAGACACATGAAAGCAAAACATCTTAGGAAAAAGTCTTACAAATGCATGGAGTGTGAATATAACACAAGCATCAGTTTATATTTAAAAGAACACATAAAAAGAAAACACCTGGATCAAAATGATTATAAATGCAGTGAGTGTGAATTCAAGACATATTACAAGTCAAGTTTAGAAAGACACATGAAAGATAAACATCTTAAAGAAAATTATTATAAATGCATGGAGTGTGAATTCAAGACGAACTACAAGTCAAGTTTGAGCGCACACATAAAAACAAAACATCTTGAAGAAAAAGCTTATAAATGCATGGAGTGTGAATACAAAACAAACATCAAGTCAAATTTTGAAATACACACAAAAAAAGAACACCTGAAACAAAATGATTTTAAATGCACGGAGTGTGAATTCGAGACAAACTACAAGTCGAATTTAGACAAGCACATAAAATCAAAACATCTCAAACAAAATGATTATAAATGCACAAAGTGTGGATTCAGTACAAACTACAAGGCAAGTTTTCAAAGACACGTGAAAGAAAAACACCTGAAACAAGATGATTATAAATGCACAATGTGTGAATTCAAGTCACACTGCAAGTCAAGTCTATACATGCACATAAAATTAAAACATCAGAAACAAAATGAATATAAATGCACAGAGTGTGAATACAAAACAAACGTCAAGTCATATTTACAAGATCACATAAAAAGAAAACACCTGGAGTATGATAGAGAAAATTATAAGTGCATGGAGTGTGACTACAAAACAAGTCGCAAGTCGTATTTAGAAAAGCACATAAAGACAAAGCATCTGAATCAAAACGATTATAAATGCATGGAGTGTGAATACAAGACAAATTATAAGTCATACTTTAAAAAGCACATAAAAGCAATACATCTGAAACAAAAGGATCATAAATGCACAGAGTGTGAATACAAGACATATTATAAAGCAGACTTGGGGAAACACATAAAAGCAAAACATCTGAAACAAGGGGATTACAAATGTTTCGACTGTGAATACAAGACAAGTTATAAATCAAACTTAGACAAACACATAAATGTAAAACATCGGAGACAAGAGGATTATAAATGCGTGGAGTGTGAATTCAAGACATATTACAAGTCAAGTTTCGAAAGACACACGAAAGAAATACATCTGACACAAAACGATTACAcgagggaagatcagtaa
Protein Sequence
MYNADFRDHINEHYEVKMYKCGICHRRYKAKESLKAHVLKNHVNNEGRGIQANIKNIGERSPHCRSKSLIKINHMNRDKYKCANCEFKTYYRSHLERHVKIKHLKQEEYKCAYKTNHKSYLNNHIKSKHCKENYFKCMRCEFKTNYKSSLVRHMKAKHLRKKSYKCMECEYNTSISLYLKEHIKRKHLDQNDYKCSECEFKTYYKSSLERHMKDKHLKENYYKCMECEFKTNYKSSLSAHIKTKHLEEKAYKCMECEYKTNIKSNFEIHTKKEHLKQNDFKCTECEFETNYKSNLDKHIKSKHLKQNDYKCTKCGFSTNYKASFQRHVKEKHLKQDDYKCTMCEFKSHCKSSLYMHIKLKHQKQNEYKCTECEYKTNVKSYLQDHIKRKHLEYDRENYKCMECDYKTSRKSYLEKHIKTKHLNQNDYKCMECEYKTNYKSYFKKHIKAIHLKQKDHKCTECEYKTYYKADLGKHIKAKHLKQGDYKCFDCEYKTSYKSNLDKHINVKHRRQEDYKCVECEFKTYYKSSFERHTKEIHLTQNDYTREDQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-