Mmel065373.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000542.1:601974-606277[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.00033 0.038 17.9 3.9 1 23 178 201 178 201 0.97 2 21 0.047 5.5 11.1 3.0 1 23 267 290 267 290 0.97 3 21 0.013 1.5 12.9 5.2 2 23 326 348 325 348 0.96 4 21 0.013 1.5 12.9 0.7 1 23 354 377 354 377 0.97 5 21 0.011 1.3 13.1 2.8 1 23 383 406 383 406 0.95 6 21 0.0026 0.3 15.0 1.1 1 23 412 435 412 435 0.95 7 21 0.02 2.4 12.2 3.0 1 23 441 464 441 464 0.96 8 21 0.0041 0.48 14.4 2.8 1 23 470 493 470 493 0.98 9 21 0.0049 0.57 14.2 1.8 1 23 499 522 499 522 0.96 10 21 0.0032 0.38 14.7 1.5 1 23 528 551 528 551 0.96 11 21 0.15 17 9.5 1.9 1 23 557 580 557 580 0.98 12 21 0.13 15 9.7 6.2 1 23 586 609 586 609 0.98 13 21 0.11 13 9.9 0.8 1 23 615 638 615 638 0.96 14 21 0.035 4.1 11.5 2.5 1 23 644 667 644 667 0.96 15 21 0.0051 0.6 14.1 4.5 1 23 673 696 673 697 0.97 16 21 0.023 2.7 12.0 1.1 1 23 702 725 702 725 0.96 17 21 0.0011 0.12 16.3 5.1 1 23 731 754 731 754 0.98 18 21 0.2 24 9.1 1.3 1 23 760 783 760 783 0.96 19 21 0.011 1.3 13.0 1.4 1 23 789 812 789 812 0.96 20 21 0.15 17 9.5 1.9 1 23 818 841 818 841 0.98 21 21 0.0016 0.19 15.7 4.3 1 23 847 870 847 870 0.98
Sequence Information
- Coding Sequence
- ATGTGGCGACCTTTTGCTGAAAGTGTTAGTGATTATGATGTGGATAGTGATAATACTGTTGGAGCACGACAGAGAAAGCATATATCAGAAGATGCAAAACAGATAATTTTCAATGTCTATCATACCCTGATGGAAGAAAATAACGAACTACAAACCAAGAACATTCAACGAACGTCGCAATTAACCAAGGTGCCTTTTGGAACAATATATAAAATAATTAAGAATAACGCAGGGCCTCGAAAGCAAAGAAGTGACAAAGGAGCACCGAGAAAAATTGAAGAGTATGAAATTGAGACTATTAGGCAGCAAGTATACTACTTCTACAGAGGAAATGTTGTATCTACACTTGACTTATTGTACTGGGTACTTTGCAAACCGGAGGTTCACGAGTTAGGGGTAGAAAGTTCGCCTGAAAGACACAAAGCCAGAAAATGGAAACGTGGAATATACAAATGTACGCAATGCAAGTTTACGACACTATACGGCGCCGACTTCAGGCACCACACTAATGAGCATTGCGAAGTGAAATTATACAAATGTGGAATTTGTCATAGGAGATACAAGACGAAGGAATCGCTCAAGACGCACGTGTTAAAAAATCATGCTAACAGTGATGAAAGGGGTATCCAAAAATACACTACGTGTGACTATTTCAAAACAAATATTATAAATATAAAGGAGAGATCTCCACATCCACACGATGGCGAAAAATGTCAATTCACGAAATGCAAATTTCAAACAAGGAACAAATGTGGCTTAAAATCACTTGTCGGAATGAGACATCTGAACAGACGCAAATATAAATGCTCAAATTGCGAATTTAAGACATATTACACGAGTTATTTAGAAAAACACATCAAAATAAAACATCTCACGGAAACTAATTATAAATGTTCAGAGCGTGAATACGAAACAAACCATGAGTCAAGCTTGGTAGGACACAAAAATGCAAAATATTTTAAACAATATGATTGTAAATGCACCGAGTGTGAATTTAACACAAACAACAAATCTTATTTAAAGAAACACATGGACACAAAACATCTTAAAGAAAATGCTTATAAATGCGTGGCGTGTGAATACCAGACGAACTACAAGTCAAATTTACAAGTGCATATAAAAGTAAAACATCTTAAAACAAATCAGTATATATGTAAGGAGTGTGAATTCAAGACAAACTACAAGTCACATTTACAAGAGCATATAAAAGCAAAACATCTTAAAACAAATCAGTATATATGTAAGGAGTGTGAATTCAAGACAAGTTACAAGTCAAGTTTACAAGTGCATATTAAAGCAAAACATCTTAATGAAAATGAGTACAGATGCATGGAGTGTGAATTCAAGACAAACTACAAGTCACATTTACAAGTGCATATAAAGGCAAAACATCTTAAAGGAAATTATTATAAATGTATGGAGTGTGAATACAAGACAAAATACAAGTCATATTTACAAGTTCACGTAAAAACAAAACATCTTAAAGTAAGCGATTATAAATGCAGGGAGTGCGAATACAAGACGAATTACAAGTCAACTTTACAAGTGCATATAAAAGCGAAACATCTTAATGAAAATGAGTATAAATGCATGGAGTGTGACTTCAAGACAAACTACAAGTCAAGTTTACAAGTGCATATAAAAGCAAAACATCTTAAAGGAAGTTATTATAAATGCATGGAGTGTGAATACAAGACAAATATCAAACCATATTTAAAAAGACACGTGAAAAGAACACATCTCAAAGAAAATGATTATAAATGCATGAAGTGTGACTTCAAGACAAACTTCAAGTCATGTTTACAACTGCATATAAAAACAAGACATCTTAACGTACGCGATTATAAATGCGCAGAGTGTGAATTCAAGACAAACTACAAGTCAAGGTTGGAAGAACACATAAACGCAAAACATCTTAAAGAAAATGATTATAAATGCATGAAGTGTGAATTCAAGACAAACTACAAGTCATATTTACAAGTGCATATTAAAGCAAAACATCTTAAAGAAAATGATTATAAATGCATGGAGTGTGACTTCAAGACAAACTATAAGTCATATTTACAAGTGCATATAAAAACAAAACATCATAAAGAAAATGGTTACAAATGCATGGAGTGTGAATACAAGGCAAACAACAAATCAGTTTTAAAACAACATATGAAAGCAAAACATCTTAAAGGACATGATTACAAATGCATGGAGTGTGAATACAAGACGAACAATAAGTCACATTTAAAAAGACATGTGAAAACAAGGCACCTTAAAGATAATGATTATAAATGCGTGAAGTGTGAATTCAAGACAGGCAACAAGCTATATTTACAAGTGCATATGAAAGCAAAACATCTTACAGAAAATGATTATAAATGCATGGAGTGCGAATTCAAGACGAACTACAAGTCAAGTTTACAAGTGCATATAAAAGCGAAACATCTTAAAGGAAATTATTATAAATGCATGGAGTGTGAATACAAGACAAATATAAAACCATATTTAAAAAGACACGTGAAAAGAACACATCTTAAACAAAATGATTATAAATGCATGGAGTGTGACTTCAAGACAAACTACAAGTCACATTTACAAGTGCATATAAAAACAAAACATCTTAACGTACGCGATTATAAAGACAAACATGACGAATTACAAATCAAGTTTACAAGTGCATATTAA
- Protein Sequence
- MWRPFAESVSDYDVDSDNTVGARQRKHISEDAKQIIFNVYHTLMEENNELQTKNIQRTSQLTKVPFGTIYKIIKNNAGPRKQRSDKGAPRKIEEYEIETIRQQVYYFYRGNVVSTLDLLYWVLCKPEVHELGVESSPERHKARKWKRGIYKCTQCKFTTLYGADFRHHTNEHCEVKLYKCGICHRRYKTKESLKTHVLKNHANSDERGIQKYTTCDYFKTNIINIKERSPHPHDGEKCQFTKCKFQTRNKCGLKSLVGMRHLNRRKYKCSNCEFKTYYTSYLEKHIKIKHLTETNYKCSEREYETNHESSLVGHKNAKYFKQYDCKCTECEFNTNNKSYLKKHMDTKHLKENAYKCVACEYQTNYKSNLQVHIKVKHLKTNQYICKECEFKTNYKSHLQEHIKAKHLKTNQYICKECEFKTSYKSSLQVHIKAKHLNENEYRCMECEFKTNYKSHLQVHIKAKHLKGNYYKCMECEYKTKYKSYLQVHVKTKHLKVSDYKCRECEYKTNYKSTLQVHIKAKHLNENEYKCMECDFKTNYKSSLQVHIKAKHLKGSYYKCMECEYKTNIKPYLKRHVKRTHLKENDYKCMKCDFKTNFKSCLQLHIKTRHLNVRDYKCAECEFKTNYKSRLEEHINAKHLKENDYKCMKCEFKTNYKSYLQVHIKAKHLKENDYKCMECDFKTNYKSYLQVHIKTKHHKENGYKCMECEYKANNKSVLKQHMKAKHLKGHDYKCMECEYKTNNKSHLKRHVKTRHLKDNDYKCVKCEFKTGNKLYLQVHMKAKHLTENDYKCMECEFKTNYKSSLQVHIKAKHLKGNYYKCMECEYKTNIKPYLKRHVKRTHLKQNDYKCMECDFKTNYKSHLQVHIKTKHLNVRDYKDKHDELQIKFTSAY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00990178;
- 90% Identity
- -
- 80% Identity
- -