Mmel132774.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010001382.1:682734-684623[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.0081 0.94 13.5 1.1 1 23 2 25 2 25 0.96 2 20 0.0042 0.49 14.4 1.7 1 23 82 105 82 105 0.97 3 20 0.049 5.7 11.0 2.1 1 23 111 134 111 134 0.95 4 20 0.081 9.5 10.3 6.5 1 23 140 163 140 163 0.97 5 20 0.015 1.8 12.6 4.2 1 23 169 192 169 192 0.96 6 20 0.14 17 9.6 1.5 1 23 198 221 198 221 0.95 7 20 0.016 1.8 12.6 0.5 1 23 227 250 227 250 0.97 8 20 0.14 16 9.6 2.5 1 23 256 279 256 279 0.98 9 20 0.1 12 10.0 2.3 1 23 283 306 283 306 0.96 10 20 0.0026 0.31 15.0 4.4 1 23 312 335 312 335 0.98 11 20 0.35 41 8.4 2.4 1 23 341 364 341 364 0.92 12 20 0.0041 0.47 14.4 1.4 1 23 370 393 370 393 0.97 13 20 0.067 7.8 10.6 2.4 1 23 399 422 399 422 0.94 14 20 0.0027 0.31 15.0 3.9 1 23 427 450 427 450 0.98 15 20 0.0065 0.76 13.8 0.3 1 23 456 479 456 479 0.98 16 20 0.043 5 11.2 3.5 1 23 485 508 485 508 0.96 17 20 0.00058 0.068 17.1 2.0 1 23 514 537 514 537 0.98 18 20 0.00091 0.11 16.5 1.2 1 23 543 566 543 566 0.94 19 20 0.0031 0.36 14.8 1.2 1 23 572 595 572 595 0.96 20 20 0.013 1.5 12.8 2.4 1 23 601 624 601 624 0.98
Sequence Information
- Coding Sequence
- ATGTACAAATGTGTAATCTGTCAAAGAAGATACAATGCTAAGGAATCGCTCAAGTCGCACGTGGAAAAATATCATGGTAACAATGATGGAACTGGTATCCAAGAAAGCACTACGTGTGACCTCTTCGAAGTAAATATTAAAAATATAAAAGAAGACGAACAATGTCAATCTTCGAAATTCAAGTCTCAAACAAAGGACAAATTAAAATCACTTATAAAAATTAAACATTTGAACAGAGGCAAATATAAGTGCGTAATTTGCGAGTTTAAGACATACTACAAGAGCTATTTAGAGAGCCACATGAAAATACAACATTCAATGGAAAGTATTTATAAATGCTCACTATGCGAATTCGAAACATACTACAAGTCAAGTTTAGAAAGACACAAAAACGCAAAACATCTTAAAGCAAGCAAGCATAAGTGCATGGAGTGTGAATACAAGACAAACTACAAGTCGCATTTAAAACTACATGTAAAAACCAGACATCTGAAAGAAAACGATTACGAATGCACAAAGTGTGAGTTCAAGACAAACTACAAGTCGCATTTAAAACTACACATCAAAGCCAAACATCTGAAACAAAATTATTATAAATGCGTTGAATGTGAATTCAGGACATTTTACACGTCAAACTTGGATAAACACATTAAAGCAAAACATCTGAAACAAAAGGATTATAAATGTGTGGAGTGTCAATACATAGCAAGTTACAGGTCAGAGTTAGAAACTCACGTTCAACGAAAACATCCTAAAGAAAAGAATTATAAATGTGCAGAGTGCGAATACAAGACACACAGTAAGTTAACTTTAGAAGTACACATAAAGAGAAAACATCTGCAAGATTATAAATGCCCGGAGTGTGAATTCAAAGCACACTACAACTCATGTTTACAAGTCCATATAAAAGCAATACATCTTAAGGAAAACGATTATAAATGCACAGACTGCGAATTCAAGACAAACTACAAGTCACATTTAAATCTGCACATCAAATCACAACATCTTAAAGAAAACGATCATAAATGCATGGAGTGTGAGTTCAAGACATTCTACAAGTCAAGTTTAGAAGCACACGTTAAAGCAAAACACACAAAACAAAATGATTATAATTGCGTGGGGTGTGAATTCAAGACAAATAATAAAGGACACTTGGAAAGGCACATAAACGTAAAACATCTTAAACAAAATGAGTATAAATGCACAGAGTGTGAATTCAAGACATGTTACAAGTCAAGTTTAGACGTGCACATCGAAGCAAAACATCTTGAAAATGTTTATAAATGCACAGAGTGTGAATACAAGACAAACTACAAGGCACATTTAAAAGTACACGTAAAGACAAAACATCTTACAGAAAATAATTATAAATGCGCAGAGTGTGAATACATGACAAGTCGTAAGTTGGGTTTAGTAGCGCACATAAAATCAAAACATCTTAAACAGAAGAATTATAAATGTAACGAGTGCGAATTCGAAACATATTACAAGTCATGTTTAAAAGTACATATAAAAGCAAAACACGTGGAACAAAATGATTATAAGTGCACAGATTGTGAATTCAAGACTAGCTACAAGGCAAGTTTAGAAACACACATAAAAACAAAACATCTGAAACAAAGTGATTATAAGTGCTTGGAGTGTGAATTTACGACAAACCGCAAGTCAAATTTAAAAATACACATAACAGGAAAACATCTTAAAGAATATAATTACAAGTGCACGGAGTGTGAATTCAAGACGATCTACAAGGCAAATTTAGAACGACATGTGAAGGAAAAACATCTGAAACAATCCGATTATAAATGCCCAGAGTGTCCATTCAAGACAACTTATAAATCGTGCATAGGTAGACACATAAGAGTTAAACATCTGAAACAGAATTATTAG
- Protein Sequence
- MYKCVICQRRYNAKESLKSHVEKYHGNNDGTGIQESTTCDLFEVNIKNIKEDEQCQSSKFKSQTKDKLKSLIKIKHLNRGKYKCVICEFKTYYKSYLESHMKIQHSMESIYKCSLCEFETYYKSSLERHKNAKHLKASKHKCMECEYKTNYKSHLKLHVKTRHLKENDYECTKCEFKTNYKSHLKLHIKAKHLKQNYYKCVECEFRTFYTSNLDKHIKAKHLKQKDYKCVECQYIASYRSELETHVQRKHPKEKNYKCAECEYKTHSKLTLEVHIKRKHLQDYKCPECEFKAHYNSCLQVHIKAIHLKENDYKCTDCEFKTNYKSHLNLHIKSQHLKENDHKCMECEFKTFYKSSLEAHVKAKHTKQNDYNCVGCEFKTNNKGHLERHINVKHLKQNEYKCTECEFKTCYKSSLDVHIEAKHLENVYKCTECEYKTNYKAHLKVHVKTKHLTENNYKCAECEYMTSRKLGLVAHIKSKHLKQKNYKCNECEFETYYKSCLKVHIKAKHVEQNDYKCTDCEFKTSYKASLETHIKTKHLKQSDYKCLECEFTTNRKSNLKIHITGKHLKEYNYKCTECEFKTIYKANLERHVKEKHLKQSDYKCPECPFKTTYKSCIGRHIRVKHLKQNY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -