Mmel065526.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000542.1:1465785-1467224[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 1.3e-05 0.0015 22.3 1.4 1 23 19 42 19 42 0.96 2 14 0.00078 0.091 16.7 1.2 1 23 103 126 103 126 0.98 3 14 0.069 8 10.6 1.5 1 23 132 155 132 155 0.98 4 14 0.00033 0.038 17.9 1.2 1 23 161 184 161 184 0.98 5 14 0.00035 0.04 17.8 2.0 1 23 190 213 190 213 0.98 6 14 1.1e-05 0.0013 22.5 0.8 1 23 219 242 219 242 0.98 7 14 6.1e-05 0.0071 20.2 1.9 1 23 248 271 248 271 0.98 8 14 9.6e-05 0.011 19.6 1.3 1 23 277 300 277 300 0.98 9 14 0.024 2.8 12.0 0.2 1 23 306 329 306 329 0.96 10 14 0.011 1.2 13.1 0.2 1 23 335 358 335 358 0.96 11 14 0.004 0.47 14.4 1.5 1 23 364 387 364 387 0.96 12 14 0.0074 0.86 13.6 1.7 1 23 393 416 393 416 0.98 13 14 0.00013 0.016 19.1 1.5 1 23 422 445 422 445 0.98 14 14 0.023 2.7 12.1 1.4 1 23 451 475 451 475 0.93
Sequence Information
- Coding Sequence
- ATGTACAACGCCGACTTCAGGCACCATACTAATGAGCATTACGGGGTGAAATTGTACAAATGTGGTATTTGTGACAAAAGATACAAGACGAAGGAATATCTCAAGGCGCACGTGGAAAAATATCATGCAGACAATGAAGGAACATGTGACTACTTCAAAGCTACTATTAAAAATGTAAAAGAGAGATCTCGACACTCACAGCATGTTGGTGGAAATCATTGTCAATGCTCGAAATGCAAGCATCAAACAGGGGCCAAAAATTACCTAAAGCCACTTATAAAAATAAAGCATCCAAACAGAGGCAAATATAAATGCCCAAATTGCGAGTATAAGATAGATAACGAGACTTATTTGAAAAGGCATATGAAAATAAAACATCTCATGGAATGTAATTACAAATGCATGGAGTGTAAATTCCGGACAGGTTACAAGTCAAGTATACAAATGCACATAAAAACAATACATCTTAAAGTAGGCGATTATAAATGCGCAGAGTGTGAATACAAGACGAACTACAAGCAACAATTAGAAAGACACATAAAAACAATACATCTTAAAATAAGCGATTATAAATGCGCAGAGTGTGAATATAAGACAAATCGCAAGCCACATTTAGAAAGACACATAAAATCACTACATCTTAAAGTAAGCGATTATAAATGCGCAGAGTGTGAATACCAGACAAGTCAGAAGTCAAATTTAGAAAAACACATAAAAACAATACATCTGAAAGTAACCGATTATAAATGTGGAGAGTGTGAATACAAGACAAACCACAAAGGAAATTTAGAAAAGCACATAAAAACAATACATCTTAAAGTAAGCGATTATAAATGCGTTGAGTGTGACTACCAGACAAACTACAGGTCTACATTACAAAGACACATAAAGACGGCACATTTGAAAGTAGCCGATTATAAATGTCCAGATTGTGAATACAAGGCTAACATCAAGCGATATTTAGAAAGCCACATAAAAGCAATACATCTGAAAGTAAGAGATTATAAATGCGTAGAGTGTGAATACAAGACAGGCAGCAAGTCAAGTTTAGGAAAACACATAAACGCGGTACATCTTAAACTAACCAATTATAAATGCGTAGAGTGTGAATACAAGACAAACCACAAGTCAAGTTTAGGAAAACACATAAAAGCAATACATTTGAAAGTAAAGGATCATAAATGCACTGCGTGTGAATACAAGACAAGCTACAAGGCAGAGTTAGTGAAACACATAAAAACAATACATCTTAAAGTAAGCGATTATAAATGCGCAGTGTGTGAATACAAGACAAACTACAAGTCAACATTACAAAGACACATAAAGACAGTACATTTGAAAGAAAGCATTTATAAATGCGCAGAGTGTGAATACAAGACAAACAACAAATCAAGTATAGAAAGCCACATCAAAAAGACAAAGCATCTTAGAAGCGTTTAA
- Protein Sequence
- MYNADFRHHTNEHYGVKLYKCGICDKRYKTKEYLKAHVEKYHADNEGTCDYFKATIKNVKERSRHSQHVGGNHCQCSKCKHQTGAKNYLKPLIKIKHPNRGKYKCPNCEYKIDNETYLKRHMKIKHLMECNYKCMECKFRTGYKSSIQMHIKTIHLKVGDYKCAECEYKTNYKQQLERHIKTIHLKISDYKCAECEYKTNRKPHLERHIKSLHLKVSDYKCAECEYQTSQKSNLEKHIKTIHLKVTDYKCGECEYKTNHKGNLEKHIKTIHLKVSDYKCVECDYQTNYRSTLQRHIKTAHLKVADYKCPDCEYKANIKRYLESHIKAIHLKVRDYKCVECEYKTGSKSSLGKHINAVHLKLTNYKCVECEYKTNHKSSLGKHIKAIHLKVKDHKCTACEYKTSYKAELVKHIKTIHLKVSDYKCAVCEYKTNYKSTLQRHIKTVHLKESIYKCAECEYKTNNKSSIESHIKKTKHLRSV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -