Mmel128581.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010001319.1:38566-40554[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 3.6 4.2e+02 5.1 0.3 6 23 55 73 52 73 0.91 2 21 0.0086 1 13.4 1.0 1 23 79 102 79 102 0.98 3 21 0.00085 0.099 16.6 1.2 1 23 108 131 108 131 0.98 4 21 0.067 7.8 10.6 0.4 1 23 137 160 137 160 0.98 5 21 0.15 18 9.5 1.1 1 23 166 189 166 189 0.96 6 21 0.33 38 8.4 0.3 1 23 195 218 195 218 0.98 7 21 0.0016 0.18 15.7 1.2 1 23 224 247 224 247 0.96 8 21 0.0058 0.68 13.9 0.7 1 23 253 276 253 276 0.98 9 21 0.0016 0.18 15.7 1.2 1 23 282 305 282 305 0.96 10 21 0.004 0.47 14.5 1.3 1 23 311 334 311 334 0.98 11 21 0.0016 0.18 15.7 1.2 1 23 340 363 340 363 0.96 12 21 0.0029 0.34 14.9 0.7 2 23 370 392 369 392 0.97 13 21 0.0029 0.34 14.9 0.7 1 23 398 421 398 421 0.96 14 21 7.9 9.2e+02 4.1 0.6 1 23 427 450 427 450 0.92 15 21 0.00013 0.015 19.1 1.0 1 23 456 479 456 479 0.98 16 21 0.53 62 7.8 0.6 1 23 485 508 485 508 0.97 17 21 0.49 57 7.9 0.3 1 23 514 537 514 537 0.96 18 21 0.0012 0.14 16.1 1.5 1 23 543 566 543 566 0.98 19 21 0.23 27 8.9 0.1 5 23 576 595 574 595 0.93 20 21 0.0079 0.91 13.5 1.4 1 23 601 624 601 624 0.96 21 21 0.011 1.3 13.0 1.8 1 23 630 653 630 654 0.97
Sequence Information
- Coding Sequence
- ATGCACGTGGAAAAAATTCATCCCGGCAATATAGGTAGACATGTCGAAAAAGACTATATCAAAGGTAACGTTCAAAATATAAAAGGAAGATCTTCACAGTCACGTGAAAAACAATATAAATGCTTGAAACATCTCAACAGAGACAAATATAAACGCGCAAATTGCGAGTTTAAGACATATTACAGGACTTATTTAGAAATGCACATGAAAACGATACATCTGAAACAAAAGAATTATAAATGCGCAAACTGTGAATACAAAGCAAACTCCAAGTCAGTCTTAGAGAAACATATAAAAACAAAACATCTAAAACAAAAGGATTTTAAATGCGCAGAGTGTGAATACCAGACATCCTTCAAGGGAAACTTAAAGGTACACATAAAAACAAAACATCTGAAACAAAATGATTATAAATGCGTAGAGTGTGAATACAAGACGGCCTGGAAGTCAAATTTAGACGTACACATAAAAACAAAACATCTAAAACAAAAGGATTACAAATGCGCAGAGTGTGAATACTGGACAAACCACAAGAGGAACTTAGAAGTGCACATCAAAGCAAAACATCTGAAACAAAATGATTATAAATGCGTAGAGTGTGAATACAAGACGGCTTGGAAGTCAAATTTAGGCGTACACGTAAAAACAAAACATCTGAAACAAAAGGATTACAAATGCGCAGTGTGTGAATACCAGACAAACAACAAGTCACACTTAGAAGTGCACATAAAAGCAAAACATCTGAAACACAAGGATTACAAATGCGCAGAGTGTGAATTCCAGGCATACTACAAGTCAAACTTAGAAGTGCACATAAAAACAAAACATCTAAAACAAAAGGATTACAAATGCGCAGTGTGTGAATACCAGACAAACAACAAGTCACACTTAGAAGTGCACATAAAAGCAAAACATCTGAAACACAAGGATTACAAATGCGCAGAGTGTGAATACCAGACAAACTTCAAGTCAAACTTAGAAATGCACGTAAAAACAAAACATCTAAAACAAAAGGATTACAAATGCGCAGTGTGTGAATACCAGACAAACAACAAGTCACACTTAGAAGTGCACATAAAAGCAAAACATCTGAAACACAAGGATTTAAAATGCGCAGAGTGTGAATACCAGACAAACTTCAAGTCAAACTTAGAAGTGCACATAAAAACAAAACATCTAAAACAAAAAGATTACAAATGCGCAGAGTGTGAATTTAAGACAAACAACAAGTCATACTTAGAAGTGCACATAAAAGCAAAACATCTGAAACAAAAGGATTATAAATGCGCAGAGTGTGAATATACGACTGGCTGGAAGTCAACTTTCGACGTACACGTAAAATCAAAACATCTAAAACAAAAGGATTACAAATGCGCAGAGTGTGACTACCAGACAAACAACAAGTCATACTTAGAAGTGCACATAAAAACAAAACATCTGAAACAAAAGGATTTTAAATGCGCAGTGTGTAAATACAAGACTGGCTGGAAGTCAAATTTAGACGCACACGTAAAAACAAAACATCTAAAAGAAAAGGACTACAAATGCGCAGAGTGTGAATACTGGACAAACGACAAGAGGAGCTTAGAAATGCACATAAAAGCAAAACATCTGAGACAAAAGGATTTTAAATGCGCAGAGTGTGAATTCAAGACAAACTACAAGGCGAGCTTAGAAAAGCACATAAGAACTAAGCATCTGAAACAAAAAGATTTTAAATACGCAGAGTGTGAATACCAGACAAACGACAAGTCAAACTTGAAACTGCACATAAAAGCAAAACATCTAAATCAACAGGACTATACATGCGTAGAGTGTGAATTTAAGACAAAATACAAGTCATATTTGCAAGTGCACATAAAAGCAAAACATCTAAAAGAAAATGATTATAAATGCGCAGAGTGTGAATACAGGACGGCCTGGAAGTCAAATTTAAAAGTACACATAAAAACAAAACATCACACGAAGTATGAACTCGAGACAAACTAA
- Protein Sequence
- MHVEKIHPGNIGRHVEKDYIKGNVQNIKGRSSQSREKQYKCLKHLNRDKYKRANCEFKTYYRTYLEMHMKTIHLKQKNYKCANCEYKANSKSVLEKHIKTKHLKQKDFKCAECEYQTSFKGNLKVHIKTKHLKQNDYKCVECEYKTAWKSNLDVHIKTKHLKQKDYKCAECEYWTNHKRNLEVHIKAKHLKQNDYKCVECEYKTAWKSNLGVHVKTKHLKQKDYKCAVCEYQTNNKSHLEVHIKAKHLKHKDYKCAECEFQAYYKSNLEVHIKTKHLKQKDYKCAVCEYQTNNKSHLEVHIKAKHLKHKDYKCAECEYQTNFKSNLEMHVKTKHLKQKDYKCAVCEYQTNNKSHLEVHIKAKHLKHKDLKCAECEYQTNFKSNLEVHIKTKHLKQKDYKCAECEFKTNNKSYLEVHIKAKHLKQKDYKCAECEYTTGWKSTFDVHVKSKHLKQKDYKCAECDYQTNNKSYLEVHIKTKHLKQKDFKCAVCKYKTGWKSNLDAHVKTKHLKEKDYKCAECEYWTNDKRSLEMHIKAKHLRQKDFKCAECEFKTNYKASLEKHIRTKHLKQKDFKYAECEYQTNDKSNLKLHIKAKHLNQQDYTCVECEFKTKYKSYLQVHIKAKHLKENDYKCAECEYRTAWKSNLKVHIKTKHHTKYELETN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -