Mmel142556.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010001545.1:49689-58574[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 8 9.3e+02 4.1 4.8 1 23 190 212 190 212 0.97 2 18 0.0011 0.13 16.2 1.1 1 23 218 241 218 241 0.96 3 18 0.68 79 7.4 5.3 1 23 308 331 308 331 0.97 4 18 0.0015 0.18 15.8 4.9 1 23 337 360 337 360 0.98 5 18 0.32 37 8.5 0.8 2 23 367 389 366 389 0.97 6 18 0.003 0.35 14.8 3.8 1 23 395 418 395 418 0.98 7 18 0.00064 0.074 17.0 0.5 1 23 424 447 424 447 0.96 8 18 0.0023 0.26 15.2 0.5 1 23 453 476 453 476 0.97 9 18 0.00064 0.074 17.0 0.5 1 23 482 505 482 505 0.96 10 18 0.0023 0.26 15.2 0.5 1 23 511 534 511 534 0.97 11 18 0.00064 0.074 17.0 0.5 1 23 540 563 540 563 0.96 12 18 0.0019 0.22 15.5 0.3 1 23 569 592 569 592 0.97 13 18 0.00082 0.096 16.6 0.3 1 23 598 621 598 621 0.96 14 18 0.0018 0.21 15.5 0.2 1 23 627 650 627 650 0.97 15 18 0.059 6.8 10.8 0.6 1 23 656 679 656 679 0.96 16 18 0.0046 0.53 14.3 0.6 1 23 685 708 685 708 0.97 17 18 0.0019 0.22 15.5 0.6 1 23 714 737 714 737 0.96 18 18 0.001 0.12 16.3 0.7 1 23 743 766 743 766 0.98
Sequence Information
- Coding Sequence
- ATGGTGCTTATCCAAATCAGAAGAATTTCAAGTGATGGAAAAGGCAAAACTTCAATTCGCTCCAGAGTCGTAATGAAGCAAGCATATTATATACAATTTAAGAATACTTTGGATAGAACTTTAAAACTTTTTTCTGAAACTGGTAGTCTCTTAAGAAAATCAGGCAGCGGGGCAGTTAAGAAACGTACACCTCAAGTTGTCAATCGTGTAGAAGAAATAATGGAAAATGAACCACAAACATCTGTTCGACATTTGAGTCAACAAATAAACCATTCTGTTGGTACAACTCACAAGTTATTAAAAAAAGATATGCAACTTTGTCCATACCGTGTCACAGCAGTACAAGAATTGTTAGAAATTGATTACCCACGTGGACTACAGTTTTGTAATTGTAAAATCATTCTTAAACAAAAACGCCTAAATCTTCAAGCCCCCACTTCACACTCTCGAAACTATTTTCTGTTAAAAACTGTGATCGTACCTTGTGTGTCACTGGAGGCTCACGAGGTAAAAACAGAAGGGCGTTCCATTATCAGAAGCAAAGTCCATAGATGGAAGCGTGAAATATACAAATGTACGCGATGCAAGTTTAGAACAATGTACAATGCAGACATGAGACACCACACTAACGAGCACTACATGGTGAAAATGTATAAATGTGGAATCTGTCACAGAAGATACAAGGCGAAAGCATCTCTCAAGGCGCACGTGGAAAAAATTCATGTTGATGATGAAGGAGGAGATGTCGAGAAACATTCTAGGTGTGACTATTTCAAAGCTAATATTAGAAATATGAAAGAGAGATCTCCACCTTTACATGTTGGTGGAAAACAATGTCAGTGCTCGAAATGCAAATTTCTAGCAAAGAAAAAATGTCACTTAAAGTCACATATAAAAATAAGACAACTAAAAAGAGGAAAATATAAGTGCGTACATTGCGAGTTTAAGACATATTACAGGTCTTATTTAGAAATGCATACGAAAATGAAACATCTCATGGAAATTGATTATAAATGCCGGGACTGTGAATTCAAGACAAGCTACAAGCATAATTTAGAAAGACACATAAATACGAAACATCTGAAACAAAAGAATAATAAATGCGCCGAATGTGAATACAAGGCAAGTAACAGCTCACGTTTAAAAGGACACGTGAAAACGAAACATCTTAAACAATATAATTATAAATGCGAAAAGTGTGAGTTTAAAACAAACAACAAGTCTAATTTTGAGTATCACATAAAGACAAAGCATCTTAAAATAAACAATTATAAATGCGCAGAATGTGAATATAATACAAACAACAAGACTAATTTAGAGAAACACATCAAGGCGATACATCTTAAAATAAGAGATTATATATGTGCGGAATGTGAATACAAGGCAAGCTTCAAGTCAGATTTAGAAAAACACATAAAGACAAAGCATCTTAAAATAAGCGATTATAAATGTGCAGAATGTGAATATAATACAAACAACAAGACTAATTTAGAGAAACACATCAAGGCGATACATCTTAAAATAAGAGATTATATATGTGCAGAATGTGAATACAAGGCAAGCTTCAAGTCAGATTTAGAAAAACACATAAAGACAAAGCATCTTAAAATAAGCGATTATAAATGTGCAGAATGTGAATATAATACAAACAACAAGACTAATTTAGAGAAACACATCAAGGCGATACATCTTAAAATAAGAGATTATATATGTGCAGAATGTGAATACAAGGCAAGCTTCAAGTCAGATTTAGAAAAACACATAAAGACAGAGCATCTTAAAATAAGCGATTATAAATGTGCAGAATGTGAATATAATACAAACAACAAGACTAATTTAGAGAAACACATCATGGCGATACATCTTAAAATAAGAGATTATATATGTGCAGAATGTGAATACAAGGCAAGCTTCAAGTCAGATTTAGAAAAACACATAAAGACAATACATCTTAAAGTAACCGATTATAAATGCGCAGAGTGTGAATACAAGACAAACTACAAGTCAATATTAAAAAGACACATAAATGCAGTACATCTTAAAATAAGAGACTATATATGTGCAGAATGTGAATACAAGGCAAGCTTCAAGTCAGATTTAGAAAAACACATAAAGAGAAAGCATCTTAAAATAAGCGATTATAAATGTGCAGAATGTGAATATAATACAAACAAGAAGACTAATTTAGAGAAACACATCAAGGCGATACATCTTAAAATAAGAGAGTATATATGTGCAGAATGTGAATACAAGGCAAGCTTCAAGTCAGATTTAGAAAAACACATGAAGACAAAGCATCTTAAAATAAGCGATTATAAATCCTCTTCCCGTTACTTTTCCGATAAGCGTCTCCAAGAATTTATTAATGCTCTTCCCATACATCCAGGCCGAGACAAAATTCCAGGAAAAGCTAATACCTTAAGACTTCTAAATACAAAAAAAAAACAAGAAAATTAG
- Protein Sequence
- MVLIQIRRISSDGKGKTSIRSRVVMKQAYYIQFKNTLDRTLKLFSETGSLLRKSGSGAVKKRTPQVVNRVEEIMENEPQTSVRHLSQQINHSVGTTHKLLKKDMQLCPYRVTAVQELLEIDYPRGLQFCNCKIILKQKRLNLQAPTSHSRNYFLLKTVIVPCVSLEAHEVKTEGRSIIRSKVHRWKREIYKCTRCKFRTMYNADMRHHTNEHYMVKMYKCGICHRRYKAKASLKAHVEKIHVDDEGGDVEKHSRCDYFKANIRNMKERSPPLHVGGKQCQCSKCKFLAKKKCHLKSHIKIRQLKRGKYKCVHCEFKTYYRSYLEMHTKMKHLMEIDYKCRDCEFKTSYKHNLERHINTKHLKQKNNKCAECEYKASNSSRLKGHVKTKHLKQYNYKCEKCEFKTNNKSNFEYHIKTKHLKINNYKCAECEYNTNNKTNLEKHIKAIHLKIRDYICAECEYKASFKSDLEKHIKTKHLKISDYKCAECEYNTNNKTNLEKHIKAIHLKIRDYICAECEYKASFKSDLEKHIKTKHLKISDYKCAECEYNTNNKTNLEKHIKAIHLKIRDYICAECEYKASFKSDLEKHIKTEHLKISDYKCAECEYNTNNKTNLEKHIMAIHLKIRDYICAECEYKASFKSDLEKHIKTIHLKVTDYKCAECEYKTNYKSILKRHINAVHLKIRDYICAECEYKASFKSDLEKHIKRKHLKISDYKCAECEYNTNKKTNLEKHIKAIHLKIREYICAECEYKASFKSDLEKHMKTKHLKISDYKSSSRYFSDKRLQEFINALPIHPGRDKIPGKANTLRLLNTKKKQEN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -