Mmel068693.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000567.1:97995-100826[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 29 0.004 0.47 14.4 1.9 1 23 19 42 19 42 0.93 2 29 0.058 6.8 10.8 1.8 1 23 108 131 108 131 0.97 3 29 1.2 1.4e+02 6.7 3.3 1 23 137 160 137 160 0.95 4 29 7.6 8.9e+02 4.1 0.9 1 21 166 186 166 189 0.94 5 29 0.069 8 10.6 2.8 1 23 195 218 195 218 0.98 6 29 0.0076 0.89 13.6 1.6 1 23 224 247 224 247 0.98 7 29 0.0011 0.13 16.2 2.7 1 23 253 276 253 276 0.98 8 29 0.058 6.8 10.8 2.1 1 23 282 305 282 305 0.98 9 29 0.0082 0.96 13.5 2.3 1 23 311 334 311 334 0.98 10 29 0.00041 0.048 17.6 1.7 1 23 340 363 340 363 0.98 11 29 0.097 11 10.1 1.6 1 23 369 392 369 392 0.98 12 29 0.007 0.82 13.7 5.5 1 23 398 421 398 421 0.98 13 29 0.011 1.2 13.1 4.3 1 23 427 450 427 450 0.98 14 29 0.082 9.5 10.3 3.2 1 23 456 479 456 479 0.98 15 29 0.004 0.47 14.4 3.5 1 23 485 508 485 508 0.98 16 29 0.082 9.5 10.3 3.2 1 23 514 537 514 537 0.98 17 29 0.19 22 9.2 1.6 1 23 543 566 543 566 0.98 18 29 0.011 1.3 13.1 1.6 1 23 572 595 572 595 0.98 19 29 0.0031 0.36 14.8 4.1 1 23 601 624 601 624 0.98 20 29 0.0036 0.42 14.6 2.4 1 23 630 653 630 653 0.98 21 29 0.015 1.7 12.6 2.2 1 23 659 682 659 682 0.98 22 29 0.0041 0.47 14.4 2.2 1 23 688 711 688 711 0.98 23 29 0.021 2.5 12.2 3.0 1 23 717 740 717 740 0.98 24 29 0.018 2.1 12.4 5.1 1 23 746 769 746 769 0.98 25 29 0.069 8 10.6 4.4 1 23 775 798 775 798 0.98 26 29 0.0059 0.68 13.9 3.2 1 23 804 827 804 827 0.98 27 29 0.0082 0.96 13.5 2.3 1 23 833 856 833 856 0.98 28 29 0.0082 0.96 13.5 2.3 1 23 862 885 862 885 0.98 29 29 0.0058 0.67 14.0 3.2 1 23 891 914 891 914 0.98
Sequence Information
- Coding Sequence
- ATGTATAACGCCGACTTCAGGCACCACACTAACGAGCATTACAAGGCGAAAATACACAAATGTGGAATTTGTGATCGAAGATATAAGGGCAAGAAATCGCTCAAGACGCACGTGGAACAAATTCATATTAACAATGAAGGAAGAGTTATCCAAAAATATTCTGCTTGTGACTATTCCAAAGCTAATAAAAATATAAAACAGAGATCTACATATTCACACGATGGTGAAAAACAATGTCAATGCACGAAATGCAAGTTTCAAACAAGGCACAAATGTCACATAAAATCACTTATAAAAGTAAAAGATTTGAACAGAGGCAAATATAAGTGCGCAAATTGCGAGTTTAAGACATATTACAGGATTTATTTAGAAAGGCACATGAAAATAAACCATCTTATGGAAAGTAATTATAAATGCGCAGAGTGTCAATTCGAAAGAAAGCACAAGTCAACATTAGGAAGACACAAAAACGCAAAACATCTTAAATTACACGATTATAAATGCATCGAGTGTGAATACCAGACGAACAAAAAGTCTAGTATGGAAACACACATAAAGCCAAAACATCTTAAATTAAATGATTATAAATGCTTGGAGTGTGAATACCAGACGCACAACCAGGCAAATTTGGAAACTCACACAAAGTCAAAACATCTTAAAATACACGATTATAAATGCATGGAGTGTGAATACCAGACGAACAACAAGGCAAATTTGGAAACTCACACAAAGTCAAAACATCTTAAAATACACGATTATAAATGCAAGGAGTGTGAATACCAGACGAACTTTAAGTCAAGTTTAGAAAGACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCATGGAGTGTGAATACCAGACGAACGAGAAGGCACATTTGGAAAGTCACGTAAAGACAAAACATCTTAAATTACACGATTATAAATGCAGGGAGTGTGAATACCAGACGAACTACAAGACAGATTTAGAAAAACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAAGGAGTGTGAATACCAGACGAACAGAAAGTCTGCTTTGGAAACACACATAAAGTCAAAACATCTTAAAATACACGATTATAAATGCATGGAGTGTGAATACCAGACGAACAAAAAGCTTAATTTGGTGACACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAAGAAGTGTGAATACCAGACGAACAACAAGACACATTTGAAAATACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAGGGAGTGTGAATACCAGACGAACAACAAGACACATTTGAAAATACACATAAAGTCAAAACATCTTAAATTAAATGATTATAAATGCTTGGAGTGTGAATACCAGACACACAACAAGGCAAATTTGGAAACTCACACAAAGTCAAAACATCTTAAAATATACGATTATAAATGCATGGAGTGTGAACAACAGACGAACCACAAGACAAATTTAGAAAGACACATAAAGTCAAAACATCTTAAATTAAATGATTATAAATGCTTGGAGTGTGAATACCAGACGCACAACAAGGCAAATTTGGAAACTCACACAAAGTCAAAACATCTTAAAATATACGATTATAAATGCATGGAGTGTGAATACCAGACGAACAAAAAGTTTGGTTTGGTGACACACATAAAGTCAAAACATCTTAAATTACACGAATATAAATGCATGGAGTGTGAATATCAAGCGAATACGAAGTCATATTTGGAAAGACACGTAAAGAGAAAACATCTTAAATTACACGATTATAAATGCACGGAGTGTGAATACCAGACGAACAACAAGACACATTTGAAAATACACATAAAGTCAAAACATCTTAAATTACACGAATATAAATGCAGGGAGTGTGAATACCAGACGAACTACAAGACAGATTTAGAAAAACACATAAAGACGAGACATCTTAAATTACACGATTATAAATGCAAGGAGTGTGAATACCAGACGAACAAAAAGGCAAATTTTGAAACTCACACAAAGTCAATACATCTTAAAATACACGATTATAAATGCATGGAGTGTGAATATCAGACGAACTTTAAGTCTAATTTGAAAATACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAAGGAGTGTGAATACCAGACGAACAAAAAGTCTTATATGGAAACACACATAAAGTCAAAACATCTTAAAATACACGATTATAAATGCAAGGAGTGTGAATACCAGACGAACAACAAGACACATTTGGAAACTCACACAAAGTCAAAACATCTTAAAATACACGATTATAAATGCATGGAGTGTGAATACCAGACGAACAACAAGACACATTTGGAAACTCACACAAAGTCAAAACATCTTAAAATACACGATTATAAATGCAAGGAGTGTGAATACCAGACGAACTACAAGACATATTTAGAAAAACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAGGGAGTGTGAATACCAGACGAACTACAAGACAGATTTAGAAAAACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAGGGAGTGTGAATACCAGACGAACTACAAGACAGATTTAGAAAAACACATAAAGTCAAAACATCTTAAATTACACGATTATAAATGCAGGGAGTGTGAATACCAGACGAACAGCAAGCCACATTTGGAAAGACACATTAAGTCAAAACATTTTAAATTACGCGATTATAAATGCATGGAGTCTGAATTCAAGACGAACTACAAGAAAAATTTAGGACCACACAAAGAGAAAACATCTTAA
- Protein Sequence
- MYNADFRHHTNEHYKAKIHKCGICDRRYKGKKSLKTHVEQIHINNEGRVIQKYSACDYSKANKNIKQRSTYSHDGEKQCQCTKCKFQTRHKCHIKSLIKVKDLNRGKYKCANCEFKTYYRIYLERHMKINHLMESNYKCAECQFERKHKSTLGRHKNAKHLKLHDYKCIECEYQTNKKSSMETHIKPKHLKLNDYKCLECEYQTHNQANLETHTKSKHLKIHDYKCMECEYQTNNKANLETHTKSKHLKIHDYKCKECEYQTNFKSSLERHIKSKHLKLHDYKCMECEYQTNEKAHLESHVKTKHLKLHDYKCRECEYQTNYKTDLEKHIKSKHLKLHDYKCKECEYQTNRKSALETHIKSKHLKIHDYKCMECEYQTNKKLNLVTHIKSKHLKLHDYKCKKCEYQTNNKTHLKIHIKSKHLKLHDYKCRECEYQTNNKTHLKIHIKSKHLKLNDYKCLECEYQTHNKANLETHTKSKHLKIYDYKCMECEQQTNHKTNLERHIKSKHLKLNDYKCLECEYQTHNKANLETHTKSKHLKIYDYKCMECEYQTNKKFGLVTHIKSKHLKLHEYKCMECEYQANTKSYLERHVKRKHLKLHDYKCTECEYQTNNKTHLKIHIKSKHLKLHEYKCRECEYQTNYKTDLEKHIKTRHLKLHDYKCKECEYQTNKKANFETHTKSIHLKIHDYKCMECEYQTNFKSNLKIHIKSKHLKLHDYKCKECEYQTNKKSYMETHIKSKHLKIHDYKCKECEYQTNNKTHLETHTKSKHLKIHDYKCMECEYQTNNKTHLETHTKSKHLKIHDYKCKECEYQTNYKTYLEKHIKSKHLKLHDYKCRECEYQTNYKTDLEKHIKSKHLKLHDYKCRECEYQTNYKTDLEKHIKSKHLKLHDYKCRECEYQTNSKPHLERHIKSKHFKLRDYKCMESEFKTNYKKNLGPHKEKTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00989985;
- 90% Identity
- -
- 80% Identity
- -