Mmel141175.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010001525.1:641185-643269[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 0.021 2.4 12.2 1.1 1 23 20 43 20 43 0.96 2 22 0.52 61 7.8 2.4 3 21 81 101 79 102 0.86 3 22 1.1 1.3e+02 6.8 4.4 1 23 110 133 110 133 0.98 4 22 5.3 6.1e+02 4.6 0.8 9 23 147 162 145 162 0.89 5 22 0.42 49 8.1 0.3 1 23 168 191 168 191 0.95 6 22 7.9e-05 0.0093 19.8 1.1 1 23 197 220 197 220 0.98 7 22 0.014 1.7 12.7 3.3 1 23 226 249 226 249 0.98 8 22 0.021 2.5 12.2 2.7 1 23 255 278 255 278 0.98 9 22 0.0013 0.16 16.0 1.6 1 23 284 307 284 307 0.97 10 22 3.3e-05 0.0038 21.0 1.1 1 23 313 336 313 336 0.98 11 22 0.0037 0.43 14.6 2.6 1 23 342 365 342 365 0.98 12 22 0.00015 0.018 18.9 1.8 1 23 371 394 371 394 0.98 13 22 0.0073 0.85 13.6 0.9 1 23 400 423 400 423 0.98 14 22 0.002 0.23 15.4 1.1 1 23 429 452 429 452 0.96 15 22 0.014 1.6 12.8 5.5 1 23 458 481 458 481 0.97 16 22 0.0016 0.19 15.7 4.0 1 23 487 510 487 510 0.98 17 22 0.8 93 7.2 3.4 1 23 516 539 516 539 0.98 18 22 0.00085 0.099 16.6 1.0 1 23 545 568 545 568 0.98 19 22 0.0002 0.024 18.5 1.1 1 23 574 597 574 597 0.98 20 22 0.0013 0.15 16.0 2.8 1 23 603 626 603 626 0.98 21 22 0.013 1.5 12.8 0.3 1 23 632 655 632 655 0.98 22 22 2e-05 0.0023 21.7 2.3 1 23 661 684 661 684 0.99
Sequence Information
- Coding Sequence
- ATGTACCACGTCGACTTCAAGCATCACTCCAACAATGAGCATTATGAAGTGAAAATGTACAAATGTGAAATTTGTTACAGAAGATACAAGTGGAAGAAATCTCTCAAAGCGCACGTGATAAAAATTCATGCTGACACTGCAGAAAGAGATGTTCAAAACATCTCTACATGTGAATATTATAAATCTAATATTAAAAATTTCAAAGAGAGATCTGCACACTCACATCATGGTAAAATACAATGCCCATGCATGAAATGTAAATTTCGAAGAAGGAACAAACGTGACTTGAAATCACATATAAAAATAAAACAACTCAAGAGAGGCAAATATAAGTGCACGAATTGCGAGTTTAAGACACATTACAGGACTTATTTAGAGGGGCACATGAAAATAAAACATCTTAAAGAAACGGATTATAAATGCGCAAAGAGCAAATATAAGACAAATAACAAGTCATATTTAAAAACACACGTGAAAACGAAACATCTTAAACAACATGTTTTCAAATGCGCGGAGTGTGTATTTAAGACAAATTACAAGTCAAGCTTGGAAGGTCACGTAAAGGCAATACATCGTAAAGAACACGATTATAAATGCGGAGAGTGTGAATACAAGTCAAGCGTGAAGTCAAATTTAGAAAAACACATAAAGACGAGACATCTTAATGAACACGATTATAAATGCGCATACTGTGAGTACAAAACAAATAACGAATCATATTTCAAAACACATGTGAAAACGAAACATCTTGAAGAACACGATTATGAATGCGCAGAGTGTGAATACAAGACAAACTTCAAGTCATGTTTACAAGCACACGTGAAAACGAAACATCTTAAAGGACACGACTATAATTGCGCAGAGTGTGACTACAAGACAAATTACAAGTCATATTTAAAAGCGCACGTGAAAACGAAACATCTTAAAGAAAGAAATTATAAATGCCCAGAGTGTGAATACAAGGCAAACCGTAATTCATATTTAAAAAAACACATAAAGACAATCCACCTTAAAGTAGGTGATTATAAATGCGATGAGTGTGAATACAAGACAAATAATAAGTCCCGTTTGAAATTACACGTGAAAACAAAACATCTTAATGAACATGATTATAAGTGTACCGAGTGTGAATACAAGACAAACTTCAACGCAAATTTAAAAAAGCATATAAAGACGGTACATCTTAAAGAACACGATTATAAATGCGAAGAGTGTGATTATAAAACAAATATTCAATACCGTTTAAAAGCACACGTGAAAACGGAACATCTAAAGGAATATGATTATAAATGCGTAGAATGTGAATACAAGACAAATAGAAAGGAAGGTTTAGAACATCACATGAAGGCAATACATCTTAAAGTAAACGATTTTAAATGCGCAGACTGTAAATTCAAGACAAATCACAAGTCACATTTAGAAGCACACGTCAAATCGAAACATCTTAAAGAACATGATTATAAATGCACAGACTGTGAATTCAAGACAAATTTCAAGTCACATCTGAAAGCACATGTGAAAACGGAACATCTTAAGGAATACGATTATAAATGCGCCGAATGTGAATACAAGACAAACTGTAATTCAAATTTTAAATTACACGTAAAGACAATACATCTTAAAGTAAGCGATTATAAATGCGCAGACTGCGAATACAAAACAAATTACAAGTTAAATTTGGAAAAACACATAAAGACAGTACATCTTAAAGAACTTGATTTTAAATGCCCAGAGTGTGAATACAAGTCAAGCAGGAAGTCAGTTTTAGAAACACACATAAAGACAAGACATCTTAAAGAACACGATTATAAATGCACGTACTGTGAATATAAAACAAATAGCGAGTCATATTTAAAAACACATGTGAAAACGATGCATCTTGAAGAACACGATTATAAATGCGCAGATTGTGACTATAAGACAAACATCAAGCCATCTTTAATAGCACACGTGAAAACGAAACATCTTAAAAAACACGACTACAAATGCAAAGGGTGTGAATACAAGACAAATTACAAATCCAATCTAGAAGTACACATGAGAACGAAGCATCTGACGGCAGCTGTCTCACTATCCCAAACCTAG
- Protein Sequence
- MYHVDFKHHSNNEHYEVKMYKCEICYRRYKWKKSLKAHVIKIHADTAERDVQNISTCEYYKSNIKNFKERSAHSHHGKIQCPCMKCKFRRRNKRDLKSHIKIKQLKRGKYKCTNCEFKTHYRTYLEGHMKIKHLKETDYKCAKSKYKTNNKSYLKTHVKTKHLKQHVFKCAECVFKTNYKSSLEGHVKAIHRKEHDYKCGECEYKSSVKSNLEKHIKTRHLNEHDYKCAYCEYKTNNESYFKTHVKTKHLEEHDYECAECEYKTNFKSCLQAHVKTKHLKGHDYNCAECDYKTNYKSYLKAHVKTKHLKERNYKCPECEYKANRNSYLKKHIKTIHLKVGDYKCDECEYKTNNKSRLKLHVKTKHLNEHDYKCTECEYKTNFNANLKKHIKTVHLKEHDYKCEECDYKTNIQYRLKAHVKTEHLKEYDYKCVECEYKTNRKEGLEHHMKAIHLKVNDFKCADCKFKTNHKSHLEAHVKSKHLKEHDYKCTDCEFKTNFKSHLKAHVKTEHLKEYDYKCAECEYKTNCNSNFKLHVKTIHLKVSDYKCADCEYKTNYKLNLEKHIKTVHLKELDFKCPECEYKSSRKSVLETHIKTRHLKEHDYKCTYCEYKTNSESYLKTHVKTMHLEEHDYKCADCDYKTNIKPSLIAHVKTKHLKKHDYKCKGCEYKTNYKSNLEVHMRTKHLTAAVSLSQT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00989878; iTF_00990039;
- 90% Identity
- iTF_00990039;
- 80% Identity
- -