Basic Information

Gene Symbol
-
Assembly
GCA_935421255.1
Location
CAKXYX010002456.1:19-3009[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 32 0.037 4.3 11.4 0.4 1 23 2 25 2 25 0.94
2 32 0.031 3.7 11.6 2.9 1 23 86 109 86 109 0.97
3 32 0.022 2.6 12.1 1.9 1 23 115 138 115 138 0.97
4 32 0.0096 1.1 13.3 1.6 1 23 144 167 144 167 0.98
5 32 0.23 27 8.9 1.6 1 23 173 196 173 196 0.97
6 32 0.0055 0.63 14.0 3.8 1 23 202 225 202 225 0.98
7 32 0.051 5.9 11.0 4.5 1 23 231 254 231 254 0.98
8 32 0.0055 0.63 14.0 3.8 1 23 260 283 260 283 0.98
9 32 0.0023 0.27 15.2 1.8 1 23 289 312 289 312 0.98
10 32 1.7 1.9e+02 6.2 4.8 1 23 318 341 318 341 0.97
11 32 0.036 4.2 11.4 6.6 1 23 347 370 347 370 0.98
12 32 0.0027 0.31 15.0 2.7 1 23 376 399 376 399 0.98
13 32 0.0055 0.64 14.0 2.2 1 23 405 428 405 428 0.97
14 32 0.096 11 10.1 4.1 1 23 434 457 434 457 0.98
15 32 0.021 2.4 12.2 1.8 1 23 463 486 463 486 0.97
16 32 0.0003 0.035 18.0 2.1 1 23 492 515 492 515 0.98
17 32 0.032 3.7 11.6 2.8 1 23 521 544 521 544 0.97
18 32 0.17 19 9.4 4.5 1 23 550 573 550 573 0.98
19 32 0.0055 0.64 14.0 1.7 1 23 579 602 579 602 0.98
20 32 0.0017 0.2 15.6 2.6 1 23 608 631 608 631 0.98
21 32 0.021 2.4 12.2 2.5 1 23 637 660 637 660 0.98
22 32 0.033 3.9 11.6 1.7 1 23 666 689 666 689 0.98
23 32 0.00024 0.027 18.3 2.2 1 23 695 718 695 718 0.98
24 32 0.032 3.7 11.6 2.8 1 23 724 747 724 747 0.97
25 32 1.3 1.5e+02 6.6 0.3 11 23 763 776 760 776 0.89
26 32 0.071 8.2 10.5 5.6 1 23 782 805 782 805 0.98
27 32 0.53 62 7.8 5.3 1 23 811 834 811 834 0.96
28 32 0.0012 0.14 16.1 2.4 1 23 840 863 840 863 0.98
29 32 0.11 13 9.9 2.6 1 23 869 892 869 892 0.96
30 32 0.24 28 8.8 5.7 1 23 898 921 898 921 0.98
31 32 0.021 2.4 12.2 2.5 1 23 927 950 927 950 0.98
32 32 0.19 22 9.2 7.3 1 23 956 979 956 979 0.98

Sequence Information

Coding Sequence
ATGTTCAAATGTGGCATTTGTGCCAGAAGATACAAGGCGAAGGAATCTCTCAAGACGCACGTAGTAAAAGTTCATATTGACAATGAAGGAAGAGATATCAAAAAATACTCTGCGTGTGACTATTTCAAAGCTAATATTAAACAAATAAAAAAAAGATGCCCAAAACAATGTCAATCCTCGAAGTACAAGTTTCAAACAAGGGAGAAATGTCATTTAAGATCACTTATAAGAGTAAAACATTTGAACAGAGGCAAATATAAGTGCACAGATTGCGAGTTTAAGACATATTACAGGACTTATTTGGAAATGCACATGAAAATAAAACACCTAATGGAATGCAATTATAAATGTGTAGAGTGTGAATTTAAGACAAACTCCAAGTCATATTTGAAAATTCACGTAACAACAAAACATCTTAAATCAAACGATTATAAATGCATGGAGTGTGAATACCAGGCGAATTTCAAGTCAAGTTTAGAAAAGCACATAAAAACAAAACATCTTAATTTAAGGGATTATAAATGCGTAGCGTGTGAATACCAGACGAACTACAAATCAAAATTGCAACTACACATAAAGTCAAAACATCTTAAATTAAAGGATTATAAGTGCGTGGAGTGTGAATACCATACGAATTTCAAGTCAAGTTTAGAAAAACACATAAAGACAAAACATCTTAATTTAAGAGATTATAAATGCATGGAATGTGAATACCAGACAAACTACAAGTCATGTTTAGAAAAACACATAAAGTCAAAACATCTTAAATTAAACGATTATAAGTGCGTGGAGTGTGAATACCATACGAACTTCAAGTCAAGTTTAGAAAAACACATAAAGACAAAACATCTTAAATCGAGCGATTATAAGTGCGAGGAGTGTGAATATCAGACGAACTACAAGTTAAATTTGGAAAAGCACATAAAGACAAAGCATCTTAAATCAAGCGATTATAAGTGCATTGAGTGTGAATACCAGACAAACTATAGGCATTATTTAAAAAAACACATAAAGTCAAAACATCTTAAGTTAAGCGATTATAAGTGCATGGAATGTCAATACCATACAAACTACAAGCATGATTTAGAAAAACACATAAAGACAAAACATCTTAAATCGAGCGATTATAAATGCAAAGAGTGTGAATACCGGACGAACTACAAGTTAAGTTTAGAAAGGCACATAAAGACAAAGCATCTTAAATCAAGCGATTATAAGTGCATGGAATGTGAATACCAGACGAATTTCAAATCAAATTTAGAAAGACACGTAAAGTCAAAACATCTTAAATTAAACAATTATAAGTGCGTGGAGTGTGAATATCATACGAACTTCAAGTTAAGTTTACAAAAACACATCAAGACAAAACATCTTCAATCAAGCGATTATAAGTGCATGGAATGTGAATACCTGACGAATTTCAAATCAAATTTAGAAAGACACGTAAAGTCAAAACATCTTAAATCAAGCGATTATAAGTGCGAGGAGTGTGAATACCAGACGAGCTTCAAGTCAAGTTTAGAAAAACACATAAAGACAAAACATCTTCAATCAAGCGATTTTAAGTGCATAAAGTGTGAATACCAGACGAATTATAAATCAGATTTAGAAAAACACATGAAGACAAAACATCTTAAATCAAGCGATTATAAGTGCATGGAGTGTGAATACCAGGCGAACTATAAGCATTACTTAAAAAAACACATAAAGTCAAAACATCTTAAATTAAACGATTATAAATGCATGGAGTGTGAATACCAGACGAACTTCAAGTCAGGTTTAGAAAAACACATAAAGACAAAACATCTGAAATCAAGCGATTTTAAGTGCATGGAGTGTGAATACCAGACGAACTTCAAGTCAAATTTAGAAAAACACATAAAGACAAAACATCTTAAATCAAGCGATTTTAAGTGCATGGAGTGTGAATACCAGACGAACTTCAAGTCGAATTTAGATAAACACATAAAGTCAAAACATCTTAAATCAAGCGATTTTAAGTGCATGGAGTGTGAATACCAGACGAACTATAAGCTAGATTTAGAAAAACACATAAAGACAAAACATCTTAAATCAAGCGATTATAAGTGCGAGGAGTGTGAATACCAGACGAACTTCAAGTCAAATTTAGAAAAACACATAAAGACAAAACATCTTCAATCAAGCGATTTTAAGTGCATAAAGTGTGAATACCAGACGAATTACAAATCAGATTTAGAAAAACACATGAAGACAAAACATCCTCAATCAAGCGATTTTAAGTGCATAAAGTGGGAATACCAGACGAATTACAAATCAGATTTAGAAAAACACATGAAGACAAAACATCTTAAATCAAGCGATTATAAGTGCATGGAGTGTGAATACCAGACGAACTATAAGCATTACTTAAAAAAACACATAAAGTCAAAACATCTTAAATTAAACGATTATAAATGCGTGGAGTGTGAATACCAGACGAACTACAAGCATTGTTTAGAAAAACACATAAAGGGAAAACATCTTAAATCAAGCGATTATAAGTGCATGGAGTGTGAATACCAGACGAACTTCAAGTCAAATTTAGAAAAACACATAAAGACAAAACATCTTCAATCAAGGGATTTTAAGTGCATAAAGTGTGAATACCAGACGAATTACAAATCAGATTTAGAAAAACACTTGAAGACAAAACATCTTAAATCAAGCGATTATAAGTGCAGGGAGTGTGCATACCAGACGAATTATAAGCATTACTTAAAAAAACACATAAAGTCAAAACATCTTAAATCAAACGATTTTAAGTGCATGGAGTGTGAATACCAGACGAACTTCAAGTCAAATTTAGATAAACACATAAAGTCAAAACATCTTAAATTAAACGATTATAAATGCTCGGAGTGTGAATACCAGACGAACTACAAGCATTGTTTAGAGAAACACATAAAGAGGAAACATCTTAAATCAAGCGATTATAAGTGCGTGGAGTGTGAATACCAGACGAACATCTAG
Protein Sequence
MFKCGICARRYKAKESLKTHVVKVHIDNEGRDIKKYSACDYFKANIKQIKKRCPKQCQSSKYKFQTREKCHLRSLIRVKHLNRGKYKCTDCEFKTYYRTYLEMHMKIKHLMECNYKCVECEFKTNSKSYLKIHVTTKHLKSNDYKCMECEYQANFKSSLEKHIKTKHLNLRDYKCVACEYQTNYKSKLQLHIKSKHLKLKDYKCVECEYHTNFKSSLEKHIKTKHLNLRDYKCMECEYQTNYKSCLEKHIKSKHLKLNDYKCVECEYHTNFKSSLEKHIKTKHLKSSDYKCEECEYQTNYKLNLEKHIKTKHLKSSDYKCIECEYQTNYRHYLKKHIKSKHLKLSDYKCMECQYHTNYKHDLEKHIKTKHLKSSDYKCKECEYRTNYKLSLERHIKTKHLKSSDYKCMECEYQTNFKSNLERHVKSKHLKLNNYKCVECEYHTNFKLSLQKHIKTKHLQSSDYKCMECEYLTNFKSNLERHVKSKHLKSSDYKCEECEYQTSFKSSLEKHIKTKHLQSSDFKCIKCEYQTNYKSDLEKHMKTKHLKSSDYKCMECEYQANYKHYLKKHIKSKHLKLNDYKCMECEYQTNFKSGLEKHIKTKHLKSSDFKCMECEYQTNFKSNLEKHIKTKHLKSSDFKCMECEYQTNFKSNLDKHIKSKHLKSSDFKCMECEYQTNYKLDLEKHIKTKHLKSSDYKCEECEYQTNFKSNLEKHIKTKHLQSSDFKCIKCEYQTNYKSDLEKHMKTKHPQSSDFKCIKWEYQTNYKSDLEKHMKTKHLKSSDYKCMECEYQTNYKHYLKKHIKSKHLKLNDYKCVECEYQTNYKHCLEKHIKGKHLKSSDYKCMECEYQTNFKSNLEKHIKTKHLQSRDFKCIKCEYQTNYKSDLEKHLKTKHLKSSDYKCRECAYQTNYKHYLKKHIKSKHLKSNDFKCMECEYQTNFKSNLDKHIKSKHLKLNDYKCSECEYQTNYKHCLEKHIKRKHLKSSDYKCVECEYQTNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-