Mdia001378.1
Basic Information
- Insect
- Meloe dianella
- Gene Symbol
- lola
- Assembly
- GCA_028455855.1
- Location
- JAPTHL010000054.1:1813580-1825141[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 1.4e-05 0.00085 19.3 1.4 3 23 18 39 17 39 0.93 2 19 0.086 5.2 7.4 0.5 1 21 48 68 48 69 0.92 3 19 0.0044 0.26 11.4 2.4 1 23 74 97 74 97 0.97 4 19 0.00041 0.025 14.6 7.1 1 21 132 152 132 153 0.95 5 19 0.36 22 5.4 4.0 1 21 185 205 185 206 0.94 6 19 0.085 5.1 7.4 2.0 1 23 214 239 214 239 0.92 7 19 0.0019 0.11 12.6 2.7 1 21 251 271 251 272 0.96 8 19 2.7e-05 0.0016 18.4 2.0 1 21 311 331 311 332 0.96 9 19 6.9e-05 0.0042 17.1 1.3 1 21 377 397 377 398 0.96 10 19 1.6 99 3.3 0.7 1 18 406 425 406 425 0.94 11 19 0.015 0.88 9.8 1.4 1 21 427 447 427 448 0.94 12 19 0.0029 0.18 12.0 1.5 1 21 456 476 456 477 0.95 13 19 0.013 0.76 10.0 1.7 3 21 481 499 479 500 0.94 14 19 1.1 67 3.9 3.0 1 20 508 527 508 529 0.89 15 19 0.00025 0.015 15.3 1.9 1 21 531 551 531 552 0.96 16 19 1.3e-06 8e-05 22.5 1.0 1 21 574 594 574 595 0.96 17 19 0.042 2.5 8.3 1.4 1 23 603 626 603 626 0.94 18 19 0.0076 0.46 10.7 1.2 1 21 683 703 683 704 0.92 19 19 0.00011 0.0068 16.4 1.6 1 23 713 735 713 736 0.96
Sequence Information
- Coding Sequence
- ATGGAAATCCGTAGTAGTATTTTGAAACAAGTAAAATTCATCAACAACATATGTCCAATTTGTTCGAAAATGTTTAAACGTAAAGATCACGTTCAACGACATTATCTTGAATTGCATATATTTAAACAAGAAAATATGGGCTATCCATGTATTTATTGCGACAAATTATTTAAACGAAAATATATTTTAGATAATCATATGAAAAACTGTATTGGACAACATAAATGTCGTCTATGTAACAGTTCATACAGTAAATTAACATTATTAATAAATCATATGACAACTGTGCACAATTCAAATTCGAGTATATCGGACGCTGCAGCTGTTCTCAAATGGGCATCAAAATCTGAAGATAAAATTAGATGTATGGTAGACTATCAACAACATCAAAGATATTTTTGTCATAATTGCGATAAAAGTTATAAACATAAACGGCATTTATCTAGCCATTTACGATATGAATGTGGTAAAGATCCAGGATTTGAATGTTTTGTTTATTATTTTTATTCTCATACAACACCATCAACAACACCAACATCTGAACAAAAACAATTCTGTTGTGCTGGTTGTAATCGTTGGTATAAATATTTACATAATTTACGTTCACATCAAAAATATGAATGTGGAAAAGAGCCGCAATTTATTTGCACCTATGAAGGATGCTCATTTAAATCGAAGAAAAAAGGCAATCTGAAACAGCACATCTTTAACAAACATGGTGTCGATTTAATTGATATACTTGAGAAACAGTTTGAATGTTTTCGTTGTAATCGTCGTTACAAATATATGAAAAATTTAAGAGCACACCAACGATATGGATGTAGTCGAGAACCGCAATTTCATTGCACATTTAAAGATTGTATGTATAGAACTACATGGAAAGGTTTCCGAAAATGTCGAACACGTGATAATTCTGGTAAGATGAATCAATTCTACTGTCCAAATTGTGGTCGTTCATATAAATATCAAAGAAATCTACATGCACATTTGAAATTTGAATGTGGCAAAGAGCCGAAATTTATATGTTATTTTGACGGTTGTTCATATCGTGCAAAAATTAAACGTAGTCTTGATTCACATATAGCAAACAGACATCGTAATAAAATGAATGATAATAATAGAAACCGTTATATGTGTTCAAATTGTGGGAAAACGTACAAATATAAAAGAGGTTTATCACAACATTTACGTTATGAATGTGGTAAGGAACGAAATTTTGTATGTAAAGAACCAAATTGTGAATATCGTTCATATAGAAAAGAACATTTGAAAAGAATCTACATCTGTGACAATTGTGGCAAATCTTATCTACATCGTGAATCTCTCTATAATCATACGAAATTTTATTGTCGAAAATCAGCCGCTTTCCATTGTAATTACTGTACATACCAAGCTAAAACTAAATGGAATTTAAAAGTCCACATAAATCGTCGTTTTGGTTGTCGATTATGCGGTAAATTCTATCAGCGTAAAGGTGCTCTTCAACATCACAAGAAATTCTATTGTCAAAAAGAACCGACATTTTCTTGTATTTTATGCAAACATAAATCGAAAACAAAATGGAATTTGAAACAACATCTACATTTACCATACAAATGTCCGAAATGTGCAAATTCGTATAAACATAAAAGTTCATTAAGTAAACATTTAAAATGGGAATGTGGTGTTGAATCGAAATTTCAATATTGTCTACAAAATTTTGAAACTGACATAGGTTCATATGTTTGTAAAGAATGTGGCCGAAGTTATAAACGTAAAAGCTCATTGTATAATCATCGACGTTGGGAATGTGGTAAAGAGCCACAATTTAGATGTGCATATTGTCCATATAAAGGCAAACAAAAAATCCATTTTATCATGCATGTTATGGCAAAACATAAAGAACATAAACATGAATGTTTATTAAGCAATACATCATTACCAACAACATCAATGAAAAAAGTCCGTAGTAAACATGGTGAAAATGGTCATTCATCCATGAGAAAATTCAAATTGTTATCAACAACAGACCAAATGGTACGGCCTGGTTATAGTAGTGAATCATTATTTGCATGTCGACATTGCGGTAAGCGTTACCGCTGGAAATCGACGATGCGCCGTCATGAACAAGTTGAATGTGGTGGTAAAGAGCCGATGTTTCAATGTACACAATGTCCATATAGGGCCAAACAGAAAGGCAATTTAGGCGTACATATACGTAAACATCATCCACAATTGATGTTTATTAATGATGCTATCACAATAAATAAGGCTGAGACAAAACAATCAACAAGCGAACAAATTTGA
- Protein Sequence
- MEIRSSILKQVKFINNICPICSKMFKRKDHVQRHYLELHIFKQENMGYPCIYCDKLFKRKYILDNHMKNCIGQHKCRLCNSSYSKLTLLINHMTTVHNSNSSISDAAAVLKWASKSEDKIRCMVDYQQHQRYFCHNCDKSYKHKRHLSSHLRYECGKDPGFECFVYYFYSHTTPSTTPTSEQKQFCCAGCNRWYKYLHNLRSHQKYECGKEPQFICTYEGCSFKSKKKGNLKQHIFNKHGVDLIDILEKQFECFRCNRRYKYMKNLRAHQRYGCSREPQFHCTFKDCMYRTTWKGFRKCRTRDNSGKMNQFYCPNCGRSYKYQRNLHAHLKFECGKEPKFICYFDGCSYRAKIKRSLDSHIANRHRNKMNDNNRNRYMCSNCGKTYKYKRGLSQHLRYECGKERNFVCKEPNCEYRSYRKEHLKRIYICDNCGKSYLHRESLYNHTKFYCRKSAAFHCNYCTYQAKTKWNLKVHINRRFGCRLCGKFYQRKGALQHHKKFYCQKEPTFSCILCKHKSKTKWNLKQHLHLPYKCPKCANSYKHKSSLSKHLKWECGVESKFQYCLQNFETDIGSYVCKECGRSYKRKSSLYNHRRWECGKEPQFRCAYCPYKGKQKIHFIMHVMAKHKEHKHECLLSNTSLPTTSMKKVRSKHGENGHSSMRKFKLLSTTDQMVRPGYSSESLFACRHCGKRYRWKSTMRRHEQVECGGKEPMFQCTQCPYRAKQKGNLGVHIRKHHPQLMFINDAITINKAETKQSTSEQI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -