Basic Information

Insect: Mellicta athalia
Gene Symbol: zfh1
Assembly: GCA_905220545.1
Location: HG992186.1:19926719-19929619[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.037 4.6 9.2 0.2 1 23 36 58 36 58 0.94

2 8 6.1e-06 0.00075 21.1 2.8 1 23 69 91 69 91 0.98

3 8 1.3e-06 0.00016 23.3 6.1 1 23 100 122 100 122 0.99

4 8 0.00013 0.016 16.9 1.0 1 21 128 148 128 149 0.95

5 8 0.0087 1.1 11.2 0.2 2 21 406 425 405 426 0.92

6 8 9.9e-06 0.0012 20.5 1.1 1 23 726 748 726 748 0.94

7 8 8.3e-05 0.01 17.6 7.6 1 23 754 776 754 776 0.98

8 8 0.07 8.6 8.4 7.1 1 21 782 802 782 803 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.037	4.6	9.2	0.2	1	23	36	58	36	58	0.94
2	8	6.1e-06	0.00075	21.1	2.8	1	23	69	91	69	91	0.98
3	8	1.3e-06	0.00016	23.3	6.1	1	23	100	122	100	122	0.99
4	8	0.00013	0.016	16.9	1.0	1	21	128	148	128	149	0.95
5	8	0.0087	1.1	11.2	0.2	2	21	406	425	405	426	0.92
6	8	9.9e-06	0.0012	20.5	1.1	1	23	726	748	726	748	0.94
7	8	8.3e-05	0.01	17.6	7.6	1	23	754	776	754	776	0.98
8	8	0.07	8.6	8.4	7.1	1	21	782	802	782	803	0.96

Sequence Information

Coding Sequence: ATGAATTTGATATCAACAGTCCGGCCGCTGGCCGGTGGGGGCGAGAGCAAGCCGCCGGAGGAAGAAGAGGAACGCGGGGGCTCGCCTCTGGGCCCCGGCGGCCCCTTCGCTTGCAGCCAGTGCCGCGGCGCCTACCCTACACGCGAGCAGCTGGAACGCCACGAGACCCTGCATTCGCCCAGCACTCAGGTGGATAACATCAAATATTCTTGCAAGATCTGCCACAAGAGCTTCGCGAATGTGTACCGACTGCAACGCCACATGATTAGTCACGACGAGAGCGCTAGCCTTCGTAAATACAAATGCAACGATTGTGATAAGGCATTTAAATTCAAACACCACCTCAAGGAGCATCTTCGAATACACAGTGGGGAGAAACCATTCGAATGTGCCAACTGTGGTAAAAAGTTTTCCCACTCCGGCTCTTATTCTTCTCATATGACGTCAAAAAAATGTCTAGTGATGAATCTCAAAATGGGAAGAATAAAGCCAAACAACCCTGCTCTCAATCCTGATCGAAGTCCATCGCGCAAACGAACTAATGCAATGGTTACATCGCAACTGAACAATAACATCACGCCAAATGGAAATTCTTTCTTACCAATTCTTCCTAAATATAGCGATGCGGCTGCCGCATTTTTCTCATCAATGTCATCACCTGAAAATAATTACCACCGACTTCCACTAGGCCAGCCAGGGATCAATCCTTTCTACATGCCTCCCGGAATGCCTATGAGTCCTGCTAACGGCATTGCTCCATATAGTTTTCCGACTTCATTAAGTCAACTTTTTGAGCAAATAGCATCACACCAATATCAACATAGAAAACTAGAAAACCCTAATCTAAAGCAAATGGGACCTCCTTCAGCAGACCCCGAAGATTTAATAGAAGAAGTAATAGATGATGAAGATAAAAGATCTGAAGGCAGCGCCGAGCTTGTAATGGATATTGAAGAGGATAACGTTTGTATAAAGAAGGAACATGAAGACCGAGAAACCGAGCAAAGGTCGCCTTCACGCGTTTATGAATCCGTCCCAGTTAACGATAACAACGCAGAGCCTGAGAACAATGACATTAACCTTAAAACGATAATGAATAGCGTTCATTCGAAACGCGATCTGTTTTTCCGGAACATGTCCCCAGTTCCTGGAAACATTTATCAAAACGCAGAGTCACCACTACCAGTTGCTATAAAAGATGAACCTGATGACTTGCGTTGCTTGAAATGCAACATTACATTCAACGATAAAAATGAACTTTTAGAACATGAAAAGGTATTATGTGGAAATATGTTCAGAAAACATGAGGGTTTAGCTGCTCAAGTGGCAGAAACTGTAGCGCTGAATCGATTAGAAGCTGAAATGCGAGCATCCATACAGAGCGGAGTTAGTGCAAGCGAAGACGAAGATCTCGGTAAAGATGACAGAGATGACAAAGTATCAATGCACGAGAATGATAGAAAAATTAGAGTTCGCACCGCGTTGAGCGAAGAGCAACAAATAGTACTGAAAGAACACTACGCAGTTAATCCACGGCCCAATAGAGAAGAATTTAAAAAGATCGCTCAACGAATCGGATTAGACAACAGGGTTGTACAAGTATGGTTTCAAAACAATAGGGCGAGGGTAAGGCGAATGACTCAAGCGATAGCAATTTTGGATCAGCCGTTAGatttatcaacaaaaaaatCTAACGCGTCTGTAACTTCTAGTCCATCGCCCTCACCGCCTTGCAGCATTTCAGTTACACATTCCGATTCTGAAGAAGCCGTTAATTTGAGCCAGAAATCTTCGCGCAGCACGACGCCACATCGCTCCAACTATCTTAACACGTATCCACATTCCAATTGCTCTTCCTCGTCGTTTACTGATTTCCGACTGTCACCATCACCGAGCGAAACGATCAATGGGCAGAAGAGATTATTGTCACAAAAGATGCCCGTCAACCCTCTGATGCCGATGGATAAACTTCTTCAATATAATGATATGACAAACGGCCGATCGCCAATGCTTAATATGCATATACCTGCGGAAAATCGAAAAGAATCCAGTCCATCCTACGACCGCCCGTCGTGGGGCGAAGAGCAAAATCAAAACGAATTTGAAGATGAAACGTCAGTACTTAAGAAAAGCAAGCTAAAGGTCGGAAATGATTTCAAAGAAGGAGAGGGACAATTTGTTTGCGACCAATGTGATAAAACTTTTGTGAAGCAAAGCTCTCTAGCGAGACATAAATACGAACATTCAGGTCAACGACCCTACAAGTGCTTGGAGTGCCCGAAAGCGTTTAAGCACAAGCATCACCTCACCGAGCACAAGAGGCTACATACCGGCGAGAAACCTTTCCAGTGCTGCAAGTGCCTCAAGAAGTTCTCTCACTCCGGCTCCTACAGTCAACACATGAACCACAGGTTTGCGATCTGCAAGCCGTACAGAGACtaa
Protein Sequence: MNLISTVRPLAGGGESKPPEEEEERGGSPLGPGGPFACSQCRGAYPTREQLERHETLHSPSTQVDNIKYSCKICHKSFANVYRLQRHMISHDESASLRKYKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPSRKRTNAMVTSQLNNNITPNGNSFLPILPKYSDAAAAFFSSMSSPENNYHRLPLGQPGINPFYMPPGMPMSPANGIAPYSFPTSLSQLFEQIASHQYQHRKLENPNLKQMGPPSADPEDLIEEVIDDEDKRSEGSAELVMDIEEDNVCIKKEHEDRETEQRSPSRVYESVPVNDNNAEPENNDINLKTIMNSVHSKRDLFFRNMSPVPGNIYQNAESPLPVAIKDEPDDLRCLKCNITFNDKNELLEHEKVLCGNMFRKHEGLAAQVAETVALNRLEAEMRASIQSGVSASEDEDLGKDDRDDKVSMHENDRKIRVRTALSEEQQIVLKEHYAVNPRPNREEFKKIAQRIGLDNRVVQVWFQNNRARVRRMTQAIAILDQPLDLSTKKSNASVTSSPSPSPPCSISVTHSDSEEAVNLSQKSSRSTTPHRSNYLNTYPHSNCSSSSFTDFRLSPSPSETINGQKRLLSQKMPVNPLMPMDKLLQYNDMTNGRSPMLNMHIPAENRKESSPSYDRPSWGEEQNQNEFEDETSVLKKSKLKVGNDFKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCLECPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00213884;
90% Identity: iTF_00985878;
80% Identity: iTF_00985878;