Math038556.1
Basic Information
- Insect
- Mellicta athalia
- Gene Symbol
- -
- Assembly
- GCA_905220545.1
- Location
- HG992202.1:13509778-13511169[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00015 0.018 16.8 1.9 1 23 109 132 109 132 0.95 2 10 3.8e-05 0.0046 18.7 2.5 3 23 141 162 139 162 0.94 3 10 0.29 35 6.4 5.3 2 23 170 192 169 192 0.95 4 10 8.7e-06 0.0011 20.7 0.9 2 23 200 222 199 222 0.94 5 10 0.013 1.7 10.6 8.2 1 23 229 252 229 252 0.93 6 10 0.0019 0.24 13.3 5.3 1 23 258 281 258 281 0.94 7 10 7.2e-05 0.0088 17.8 0.3 2 23 289 310 288 310 0.97 8 10 0.0013 0.16 13.8 2.2 2 23 318 340 317 340 0.96 9 10 9.5e-05 0.012 17.4 3.0 2 23 347 369 346 369 0.94 10 10 4.6e-05 0.0057 18.4 3.9 1 23 379 401 379 401 0.97
Sequence Information
- Coding Sequence
- ATGGAGGAATCGATGTACCAATATCAACAACCGACAATGGAAGACGTATATCCTCCCAAAGTTGAGGGTCATTTCCTCGATGATAAGGCCCAGGAATATCCACCAGCTATGCCAGAAAACTATTCCATGCCTAAACAAGAACTAGCGTACCCACCCCCAAAGCCAGAAGAACAGATGATTCCAAGGCCAGGCCCGATGCCCAATCGTCCACCGACCAAGTTCATAAGTGTCACCAGTTCCGCATTGACAGAAGAACAAAGAGCGGTGTATGAATCTGTCCTTTCCACGTGGAAGCCAGTCTTGTTTCCAAAGCGTACCAAACGCTACATATGCGAGAAGTGTAATAAAGAGtttaagaattatcaaaatctgtACCTCCATACGACCAGAGTGCATTCCTCTGAAGAATCAGCAGTAATTTGTGATATATGCGATAAAACCTTCAAGAATAAGCACTACCTATACATGCATCGAATGAATAAACATTATTCCGAATCGGAGAAATGCTATTGCCAGTTCTGTCTCCAAGAGTTCAGGACGAGGCGAGCGCTGCATATGCACGTTAAACGCATACACCCAAATACATTGCCCGAGATAAAATGTCCAGAATGTGGCAAAGAGTTTTCCGTACCTTACAAGTTGAGATACCATATGGACAATTGCCATAGACCAGATCAGGACAAATACAAGTGCCATATTTGTCAAAAGTTGTACAAAAGTCATCTGAATCTGAACAGACATCTGCATTTTCAGCATTCTCAAGTTGAAAGGCACCCCTGTGTGTTTTGTCCCATGACGTTCAAGTCCAGACATCATATGAAACGCCACATTCTTAATATTCATCCGCCGCTTGAATCGAAAGTGACTTGTCCGGAATGCTTGAAGGAATTCAAGAATGATCAGTACTTAAAAGAGCACATGCAGGTGCATACGTCTTTCGAGAAGAAAGTGAAATGCGAGCTTTGCGATAAGTTTTTCCATTCGGCGGTGCGTTTGAAAAAGCACAAGAAAATCGTGCATCCAAACAAGCCTAAGATACGCTGCGAGAAATGTGACAAGGAGTTCGCGCATGCGCACTACCTGCGTCGCCATAACAACTCCGTGCACGTAGAACTCGATGAAAGCAACTACCAGCACGAATGCGACCAGTGTGGGAAGAAATTCAAGATAAAGAGATATTTAAACAACCATCTGCAAAGACACGAACAGCAACACTTGAAGCGTATATCGCAAATGGTGAAAACTGTGATGGACGAAGGGGAAGCCCCGCCCAAGATCGCCAGGAGACGGGGAAGGCCACGAAAGGCGAGAAAGGAAATTGAGTTCATAAAATGCGAACCTGTTTCCAGTTCAGAATCTGAATCGGGCGAAACGGATTCCGAATCCGAATAA
- Protein Sequence
- MEESMYQYQQPTMEDVYPPKVEGHFLDDKAQEYPPAMPENYSMPKQELAYPPPKPEEQMIPRPGPMPNRPPTKFISVTSSALTEEQRAVYESVLSTWKPVLFPKRTKRYICEKCNKEFKNYQNLYLHTTRVHSSEESAVICDICDKTFKNKHYLYMHRMNKHYSESEKCYCQFCLQEFRTRRALHMHVKRIHPNTLPEIKCPECGKEFSVPYKLRYHMDNCHRPDQDKYKCHICQKLYKSHLNLNRHLHFQHSQVERHPCVFCPMTFKSRHHMKRHILNIHPPLESKVTCPECLKEFKNDQYLKEHMQVHTSFEKKVKCELCDKFFHSAVRLKKHKKIVHPNKPKIRCEKCDKEFAHAHYLRRHNNSVHVELDESNYQHECDQCGKKFKIKRYLNNHLQRHEQQHLKRISQMVKTVMDEGEAPPKIARRRGRPRKARKEIEFIKCEPVSSSESESGETDSESE*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01265142;
- 90% Identity
- iTF_01402909;
- 80% Identity
- -