Math028540.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mellicta athalia
Gene Symbol
-
Assembly
GCA_905220545.1
Location
HG992195.1:681950-688364[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 3e-07 3.8e-05 25.2 1.0 2 23 437 458 437 458 0.97
2 11 8.4e-06 0.001 20.7 4.9 1 23 466 489 466 489 0.97
3 11 0.1 13 7.8 0.1 1 23 495 517 495 517 0.93
4 11 0.052 6.4 8.8 3.6 1 23 523 545 523 545 0.96
5 11 0.061 7.5 8.6 4.3 1 23 677 699 677 699 0.98
6 11 0.00027 0.033 16.0 2.0 2 23 706 728 705 728 0.92
7 11 4.4e-05 0.0054 18.5 0.8 1 23 734 756 734 756 0.94
8 11 1.7e-07 2.1e-05 26.0 1.4 1 23 762 784 762 784 0.99
9 11 0.00016 0.02 16.6 1.0 1 23 790 812 790 812 0.97
10 11 2.8e-05 0.0034 19.1 2.0 1 23 818 840 818 840 0.97
11 11 0.1 13 7.8 5.4 1 23 846 869 846 869 0.90

Sequence Information

Coding Sequence
ATGGCTGCTTCGGAGAGAGGTTGTTGTGTGCCGGGATGCGCTAAAACTCGCCAAGATGAAACAGTCCTGCATTCATTTCCTAATCCTGACAAGGATATGGATCGGTATATGGCGTGGACTCGAGCTGTTGGACTTGATTCGTCATTGGACCCCCACTATGTATATCTAAATCGACGAGTGTGCCATGCTCATTTTGAATTGAAATATTTGACATGGACTAGAAGATTGAGTGCTGGGGCCATTCCAACTTTGCTCTTGCCAGGTTCTGAAACGGCTACAGCTCCACCAATTGACATCAAATACAGGTCTGAAAATGTTTCTTTAGATACTGCAATGCCATCCACTTTTAGAGATGGTCGAGACAACTCGAAGCTGTGTCGCGTTTGCGGCAAAAACGATATGACCCTAATACATTTATTTAGTGAAGAAGCATCACACAATAACTTGGtgcaaaaaattaacaaatacctACCCATTGTGGTGGATCTACATGACAAATTACCTCTGGGTGTTTGCCAGCCGTGTGTCACTGCAGTGTTGAATTGGCACAGTCTAGTGCAGTGCTGCATAGAGACAGACAAGTTACTGGCTTTAACGCTCAAACATACGTCACAGCTTCAAAACAGTAAAGAATCTAACTACAAACCAAACGGTGAAAATTCTACTAGAAATGATGCAAAGGCGAGGTTAtcaactaataatttaatcttaATATTGAAAGAAGTTTTAAATGATTACTTCAAGATTCTGAATGTCAACGAAGACAATTCGGATTTAATGTATGTGTGTCAAATGTGCCCCGAGAACCCGGCAGCGACATCTATAGAATGTTTGCATGATCATTTGATATCGTCTCATAATCGAGAGCTTTGTGACAAGTCAGCTATTGAGACATTTGTAAAAGAAAACATTACATTCGAAGAAGTCCTGAATAATGATGAAGTATCAGATAACGAGTTAGAGAAACATGTTGCggatatacctaattattattgCCCGTGTTGTGAGAGTGTGTTTTCATCACCAACTCGTCTCATATGTCATCTGAACAAACATGTAGAAGTGAGCATCGACGACGGGGTCTTGTGTTGCAATAGTCTATACTCAGACAAAAAATCATTCGTTTTACATTTGCAAGAGaaacatgtaaataaaatcACAGAGACCGTGTTAATCTGCAAAACATGTGGGTCTGTCGAAGAAAACATGGAGGCATTGGAAATACACATTAACGAAAAACATTCAGATATCGAATACGAGAAGAAAAAGGTAGAGCCGAATCCGAAATGCCAGAAGTTCATTCCTGCCGTATGCCCTGAGTGCAACAAAACCTTTTCCAATAAATACAACATGATGAAACATATGGAGAGCCATACCAACGTAACGAACTGCAAGTTTGTGTGTGATAAGTGTAATAAGACGTACAAGAGTCGAAGTAGCCTGACTCATCATCAGAAGGTGTTCCACGAAGGTTGCCTACCGTTCCTATGCTCCATGTGTGGTGAGGGCTTCCCGACTCGCATAGCCAGGGACACTCACGCGCGCATCCACACTGGCTTCAAACCGTTCACTTGCCAGTATTGCAACAAGTCGTACCGAGCACAGAACACACTCGATTGCCACATACAAATGCATCTAAACATACGGAAATGGACGCCCCACTGGGAGCGGAGTTGTAGCGAGCAGAGGATACATGAATATGATACTCATGATTTTGAAGAGACCGACAGACTCGCCTCCGATGATGATGACCAACCTCTTGCGAATATAGCGACAAAAAAATTGGAcgtatttcaaaatttttacaGAGCGCTTAAAAACTTCCGAAATCACTTCATGGAGGAGCACGATCGCTGTCAATATTCGGATTTCTCCGATTCTAGCGTGTCCGAAAACGAGGACACGGGTGCGGGTGATTTAAATAGTTTCGACGATTTGACACAAAACAACATGAGAAAGGACAAAATGGACGAGGATACTCGACTCGAACTGAATCAAGTGCAGACGAAAGTAAACGGAAAAGTATATTTTACATGTCGGACCTGCGGCAAGAACCTCAGTTCGACACATACCTACATCTACCACAAGCGCATCCACACGGGCGAGAGACCCTGCGTGTGCCACATCTGCGGCAAACAGTTCCGCGCGCCCAACGGTCTGCAGCGACACCTCACGGAGACGCACGAGCGGCAACGACGCTACATTTGCATCATGTGCACAAAGAACTTCGCCAACTCGCAGAACCTCAAGCAACACATGCGCATCCACACGGGCGAACGGCCCTACGTGTGTCCGCAGTGCGGAAAACGCTTCACTCAGAGCGGATCGCTACACGTGCACCTCAAGACGCACGGAGCGCAGCTGCCGCACGTGTGTGCGGAATGTGGGGCGCGCTTCCGCCTGCGGAGTGGGCTGACGCGCCACCGCCTGCGGCACTCGAGTGAGCGGCCACACGTCTGCTCCGCCTGCGGAAAGGCCTTCCGCCAGCGGCACGCGCTGACCGCCCACACGCTCACGCACTCCGACAGCAAGCCGCACGCCTGCGACATGTGCGGGTCCGCTTTCCGCCAGCGCCGCGCGCTGCGACACCACTGCAAGCGTCTGCATGATACACAGACGACACATGACGCACACGCGACACACGACACACTCGCGACACACGACACACTCGCGTCACACGACACAAACGCTACACACAACACACACGCGTCGCACCAGCCCGGCGTCGCGCACACGACGCTGATATACGACCACGGGGCGCACTACGGGTGA
Protein Sequence
MAASERGCCVPGCAKTRQDETVLHSFPNPDKDMDRYMAWTRAVGLDSSLDPHYVYLNRRVCHAHFELKYLTWTRRLSAGAIPTLLLPGSETATAPPIDIKYRSENVSLDTAMPSTFRDGRDNSKLCRVCGKNDMTLIHLFSEEASHNNLVQKINKYLPIVVDLHDKLPLGVCQPCVTAVLNWHSLVQCCIETDKLLALTLKHTSQLQNSKESNYKPNGENSTRNDAKARLSTNNLILILKEVLNDYFKILNVNEDNSDLMYVCQMCPENPAATSIECLHDHLISSHNRELCDKSAIETFVKENITFEEVLNNDEVSDNELEKHVADIPNYYCPCCESVFSSPTRLICHLNKHVEVSIDDGVLCCNSLYSDKKSFVLHLQEKHVNKITETVLICKTCGSVEENMEALEIHINEKHSDIEYEKKKVEPNPKCQKFIPAVCPECNKTFSNKYNMMKHMESHTNVTNCKFVCDKCNKTYKSRSSLTHHQKVFHEGCLPFLCSMCGEGFPTRIARDTHARIHTGFKPFTCQYCNKSYRAQNTLDCHIQMHLNIRKWTPHWERSCSEQRIHEYDTHDFEETDRLASDDDDQPLANIATKKLDVFQNFYRALKNFRNHFMEEHDRCQYSDFSDSSVSENEDTGAGDLNSFDDLTQNNMRKDKMDEDTRLELNQVQTKVNGKVYFTCRTCGKNLSSTHTYIYHKRIHTGERPCVCHICGKQFRAPNGLQRHLTETHERQRRYICIMCTKNFANSQNLKQHMRIHTGERPYVCPQCGKRFTQSGSLHVHLKTHGAQLPHVCAECGARFRLRSGLTRHRLRHSSERPHVCSACGKAFRQRHALTAHTLTHSDSKPHACDMCGSAFRQRRALRHHCKRLHDTQTTHDAHATHDTLATHDTLASHDTNATHNTHASHQPGVAHTTLIYDHGAHYG*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-