Basic Information

Insect: Melitaea cinxia
Gene Symbol: THAP6
Assembly: GCA_905220565.1
Location: HG992234.1:4047451-4069971[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.49 52 5.3 0.7 1 23 357 379 357 379 0.97

2 11 0.00033 0.036 15.3 7.0 1 23 386 408 386 409 0.95

3 11 1.4 1.5e+02 3.9 2.3 1 23 413 435 413 435 0.97

4 11 0.051 5.5 8.4 1.8 1 23 440 463 440 463 0.97

5 11 0.011 1.1 10.6 0.2 1 23 467 490 467 490 0.93

6 11 0.013 1.4 10.3 0.5 3 21 504 522 503 527 0.93

7 11 1.2 1.3e+02 4.1 0.4 2 23 578 600 577 600 0.94

8 11 0.0076 0.81 11.0 1.1 2 20 616 634 615 637 0.89

9 11 0.0005 0.053 14.8 0.4 1 23 643 665 643 665 0.97

10 11 8.3e-06 0.00089 20.4 1.5 1 23 671 693 671 693 0.97

11 11 4.3e-05 0.0046 18.1 4.1 1 23 699 722 699 722 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.49	52	5.3	0.7	1	23	357	379	357	379	0.97
2	11	0.00033	0.036	15.3	7.0	1	23	386	408	386	409	0.95
3	11	1.4	1.5e+02	3.9	2.3	1	23	413	435	413	435	0.97
4	11	0.051	5.5	8.4	1.8	1	23	440	463	440	463	0.97
5	11	0.011	1.1	10.6	0.2	1	23	467	490	467	490	0.93
6	11	0.013	1.4	10.3	0.5	3	21	504	522	503	527	0.93
7	11	1.2	1.3e+02	4.1	0.4	2	23	578	600	577	600	0.94
8	11	0.0076	0.81	11.0	1.1	2	20	616	634	615	637	0.89
9	11	0.0005	0.053	14.8	0.4	1	23	643	665	643	665	0.97
10	11	8.3e-06	0.00089	20.4	1.5	1	23	671	693	671	693	0.97
11	11	4.3e-05	0.0046	18.1	4.1	1	23	699	722	699	722	0.95

Sequence Information

Coding Sequence: ATGCTAAATTTAAAAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAAGAACGACTCAAAGCACATATCCAAATCTCAAGGAATAACTTTTCACGTCTTCCCATCGGAACCAAACCTCCGTGCCTCGTGGTTGAAAGCAGTTGGAAAGGACTCGTGGTCGCCGCGAGACAGGAGCACTGTCTGTTCAGAACATTTCTCACCAAGTGATTTATATGAGACTAAGAGTGGTCTGAAAAAGGTTAAGACTGGTGCCATTCCTATATGTACGCAGGATACTTCAGTCGATTGTGGTGAATCGGTCAGTTTGAAGGTATGCAGAATATGTCTCGCCGTGGATTTACATCTACACCCCATGAGTATGTGTAAATTGGAAAAAGCCTATGAGAACCTAACTGGAATCACGTTATCTAATGAAGATGAGTTACCACAGAAGCTGTGCACAGAATGTGCTAGAAGGTTACTGAATAGTGATAAATTACGAAGCAGAAGTCTAAGGGCCAATTCGTTGCTGCAAGAAATAGTTAAGAAGCAGAAGATTATAACAGTACAGAGTATCGCTGCAATCAATCGTGAGGACAACCATCTAGCTTCGGTTTTGACTAAAAAGTTATTTGAACCCGAACACTATGATTCTTACATAGAATACAATGAAGCACAAGACGAACAAACGGACAAAACTCCGATACAGGAAATAGAAGATATTAAAAGCGAGAAGAATGAAGAAATATTCATTAATGAAATATACACCGAGAGTAATAATGATGTAATTAATGAAAATAATGATAATGATTTCGTTGTAACAAATTACTCGTCAGACGACAGTTTACCTCTAGAAACTCAGAGGAAGAAAGTCAAAAAGATCAAGACGAAGGAAAAGAAGAGAAAAAAGGTTGAAAAGATTCAGAACGAACCGAAGATAGATAGACGGAGAAAACCCTTCCTGAATGATGATTTGAATGAAACACTGTTTACTATAACTGACTTGACGTTTGAAGAACAAGTTGCAGAGATAAATAAGAGGCGGGAGACATCAAATTATAAGAATTCTATGTACAAATGTACGGCTTGCTTCAAAGGATTCTTAGATGAAACGGCGTATAACGGACATATGACAAGACACACTAACCAATGCGGCGAGTACGAGTGCGACATCTGCAAGACCCACTTCAAGCACCCGCACGCGCTGCGGAAGCACATCACGGCGCACCACACGCAGCGCTTCAGCTGCAACCGCTGCGTCTACGTCACCACGCACAGACAGACGGCGAGACTACACGAGAGGTGGCACAAAGGCACCAAATATCAGTGTCCTCACTGTCAAGATGAGTTTGTAAAGTTCACGACGTACATGGGTCATATTCGGATCAAGCATCCCTCAGACTTTGTGTGCGGCCTGTGCGGGTACTCCTTCGTGAGCGAGAAGGGCATCGAGCTGCACAAGAAACTCAAGCATCGCCTGCACGACGGAGTGATCCCCGACGACGGCCCGCTCTGTGAGTTGTGCAACGTAAGGTTCGTCTCTCAAGAAGCATACAGGAGACACCTGCACGTCTCCGCGAGGCATAACAGCAGCGACTCGGACTCGAAGGAATTGAACAAATCGAGAAAACGAACTCGTGCAGTCAGAGAGAAGAAGCAAGACACTGAAAATACAGATGATGACGAAAGAAAGAAGTTATACCCCAGTCAGATGAGGAAAGCTGAAGGGCCCATACCTTGTGAACAGTGTGGCCTCCAACTGGAAGATTCCCGAGCATATCATGGCCACTTCCGGCGAATGCATCCGGACAAGAACCGCACCAACTACCCTTCGATGAAGTCACCCTGCATGTGTGAAGTGTGCGGACGAATGTTTCAAAGCTACGCGCTGTTGAAGGATCACCGCTGGACACACACCGGCGAGCGACCTTTCGCGTGCGATGCGTGCGGGAAGCGGTTCCGCATGCGGCAGCGGCTCGTGGCGCACCGCCGTGTGCACGCGCCGCGCAGGCAGTACGCGTGCGCGCTCTGCGGGAAGGCGTTCAGCACGCACAGCAACCGACAGCGACACATGTTCATCCACACAGGGCTGAAGCCGTTCAAATGCGAGATGTGCGGCAAGTGCTTCAAGCACGCGAGTGAGAAACGGGCCCATATAACATACGTACACTTGAAGAAGCCCTGGCCGAAGAGGGCAAGGGGCAAGCGACGGGCGGACAGGCCCGGTCAACTAATGGGTCAAGATTCATTGGCAGGAGCGAGTGAAATGGACATCCCTCAACCAATGTGGACCAACTGCGACCCCAAGATTGGAGACATCAACAACATAATAGATGACAAGCCTATTTATTATAACCTTAAAATATAA
Protein Sequence: MLNLKXXXXXXXXXXXXXXXXKNDSKHISKSQGITFHVFPSEPNLRASWLKAVGKDSWSPRDRSTVCSEHFSPSDLYETKSGLKKVKTGAIPICTQDTSVDCGESVSLKVCRICLAVDLHLHPMSMCKLEKAYENLTGITLSNEDELPQKLCTECARRLLNSDKLRSRSLRANSLLQEIVKKQKIITVQSIAAINREDNHLASVLTKKLFEPEHYDSYIEYNEAQDEQTDKTPIQEIEDIKSEKNEEIFINEIYTESNNDVINENNDNDFVVTNYSSDDSLPLETQRKKVKKIKTKEKKRKKVEKIQNEPKIDRRRKPFLNDDLNETLFTITDLTFEEQVAEINKRRETSNYKNSMYKCTACFKGFLDETAYNGHMTRHTNQCGEYECDICKTHFKHPHALRKHITAHHTQRFSCNRCVYVTTHRQTARLHERWHKGTKYQCPHCQDEFVKFTTYMGHIRIKHPSDFVCGLCGYSFVSEKGIELHKKLKHRLHDGVIPDDGPLCELCNVRFVSQEAYRRHLHVSARHNSSDSDSKELNKSRKRTRAVREKKQDTENTDDDERKKLYPSQMRKAEGPIPCEQCGLQLEDSRAYHGHFRRMHPDKNRTNYPSMKSPCMCEVCGRMFQSYALLKDHRWTHTGERPFACDACGKRFRMRQRLVAHRRVHAPRRQYACALCGKAFSTHSNRQRHMFIHTGLKPFKCEMCGKCFKHASEKRAHITYVHLKKPWPKRARGKRRADRPGQLMGQDSLAGASEMDIPQPMWTNCDPKIGDINNIIDDKPIYYNLKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00986624;
90% Identity: iTF_00985198;
80% Identity: iTF_00985198;