Basic Information

Insect: Melitaea cinxia
Gene Symbol: Zfy2
Assembly: GCA_905220565.1
Location: HG992234.1:5212877-5225469[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0021 0.23 12.8 1.3 1 23 195 218 195 218 0.95

2 11 0.00097 0.1 13.8 4.2 1 23 225 247 225 247 0.99

3 11 0.0051 0.55 11.6 0.3 1 23 251 274 251 274 0.96

4 11 2.5e-05 0.0027 18.8 1.4 1 23 313 335 313 335 0.98

5 11 0.0031 0.33 12.3 1.1 6 22 350 366 346 370 0.88

6 11 0.00077 0.082 14.2 0.6 1 23 409 431 409 431 0.98

7 11 0.014 1.5 10.2 0.7 3 22 441 460 439 464 0.90

8 11 1.1e-06 0.00012 23.1 0.5 1 23 472 495 472 495 0.96

9 11 0.00016 0.017 16.3 1.2 1 23 501 523 501 523 0.97

10 11 2.2e-05 0.0023 19.0 1.0 3 23 532 553 530 553 0.92

11 11 0.018 1.9 9.8 3.1 1 23 559 582 559 582 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0021	0.23	12.8	1.3	1	23	195	218	195	218	0.95
2	11	0.00097	0.1	13.8	4.2	1	23	225	247	225	247	0.99
3	11	0.0051	0.55	11.6	0.3	1	23	251	274	251	274	0.96
4	11	2.5e-05	0.0027	18.8	1.4	1	23	313	335	313	335	0.98
5	11	0.0031	0.33	12.3	1.1	6	22	350	366	346	370	0.88
6	11	0.00077	0.082	14.2	0.6	1	23	409	431	409	431	0.98
7	11	0.014	1.5	10.2	0.7	3	22	441	460	439	464	0.90
8	11	1.1e-06	0.00012	23.1	0.5	1	23	472	495	472	495	0.96
9	11	0.00016	0.017	16.3	1.2	1	23	501	523	501	523	0.97
10	11	2.2e-05	0.0023	19.0	1.0	3	23	532	553	530	553	0.92
11	11	0.018	1.9	9.8	3.1	1	23	559	582	559	582	0.97

Sequence Information

Coding Sequence: ATGTCTTTTAGAGATAGAATTATGACTGAAGTATGCTATGGGTGTCTTAATAATGACCGCAGGATGGTGAAAATAGAACAATACGATGTAAAACAGTGTTTTTTACAAATTATTAGTGAATTACCGATTACGTTAGCAGATATACAAGTTCAACTTTGCTATGAATGTGCCGCCCTATTATTGAAGTTTACCAAGTATAAACGAAGAATATTGGCCTCATATAAAACTATTCAAGATAACGTTCAAGATTTATTGATATACAAGAGCTTAAAATATAACAATTTAGAAATAAAAAACCTATATAATATATCAACACCATATCCTCAAATAGACGATGAAATGCCTCAAATAGAAATAATTAAAACAGAACTAAATACGGACGAATGTGTATCAGATATAAAAGAAGAATGTGACTTCTCAGACGATGAACCATTAATTAAAGTTAAAAAGAGAAAGAAAAAGAATGGACATATTAAGAAGGAGACCGAAGATGCACAGTATATAGAAGTAGAGTTAAATAGAGATGAAATAGCAGAAGAAATGAAGGCTCTATCGACCAGAGAAGATTATGTTAATGCAATGTTTAGGTGTGAGAAATGTTTTTCATCGTTTCCTAATGCAGATGATCTTAGTGATCATATACATCTCAAGCATGAACTGAACTCATCAAAATATAAATGTTCAATATGCGAGTGTTCGTTTTCAACGGAGGTGTCATACAACTATCATACAAACAAACATGCAAGGAGGTACCAGTGCGTTGTATGTGTGGAGAGATTTAGCAGCAAGCGAGGTGTTTTGAAACACTACAATCTGGTACATTGTCACAGAACGAACATGGAATATAATTACGGTGATAATTTGGACAATTGTGATGATGTGATGTGTAACGCTGATGTTCGTCAAGATCAAGATATCAGTGCACAAGAACAGACATTCCCCTGCGAGTTTTGTGGGAAAACCTTCAAGTGGCGAACGTCCCTCAGGAAACATCTGGAGACGCATAGAATCGAAACCGGGGAGAAGAGGAAACCGTACTGCGCGCCTTGCAGATTGTCCTTCACAACCACCTCGAACTTACAGAAACATGTCCGAACAAGTTCAAAACATCAAATACAACTTAAATTAAGGAAGCTAACAGAATCACTACCGGATCTGACCGGTCCGGACAGACACAAAGCTCAGCTGGAGATTAGGACATCCGTAAATAAATCGAGACTCCAGTATCCTTGCACTCAATGTGATAAACGTTTCCTTTGGAGAGGGAATTTGTTGAGACATATGAACAGTCATGCAGCAAAGGCCAACGGTGACCTAATATGCAAGCCCTGTAACAGAACGTTTTCATCAATAGCGACCTACCAGCAACACATGAAGATAAGTAAGAAACACGTGTCCGAAAACGACTTCAAATTCATGTGTAGTGACTGCGGTAAGAAATTCCCTACAAAGTCTCGTCTGAGAGATCATATCAACTGGGAGCACTTGAAAAACTTCGTATATAGCTGCGATGAGTGTCAGAAGGTATTCAAGACTAGCAACTCGGTGTATCTGCACAAGCAAGTGCATAAGAAGGACGTCATCGAGCATTTGTGTGATCACTGCGGGAAGCCGTTTCCGAGCCAGGCGAAGCTCCGCAGCCACATCCTGGGCCTGCACTCCCGCGCGGCGCCCTACCGCTGCCCGGCCTGCGGGGCGCGCTTCTCCTGGCACTCCTGCCTGTCGCGGCACGTCCGCCAGAAGCATCGCCGCGACGACGCCTAA
Protein Sequence: MSFRDRIMTEVCYGCLNNDRRMVKIEQYDVKQCFLQIISELPITLADIQVQLCYECAALLLKFTKYKRRILASYKTIQDNVQDLLIYKSLKYNNLEIKNLYNISTPYPQIDDEMPQIEIIKTELNTDECVSDIKEECDFSDDEPLIKVKKRKKKNGHIKKETEDAQYIEVELNRDEIAEEMKALSTREDYVNAMFRCEKCFSSFPNADDLSDHIHLKHELNSSKYKCSICECSFSTEVSYNYHTNKHARRYQCVVCVERFSSKRGVLKHYNLVHCHRTNMEYNYGDNLDNCDDVMCNADVRQDQDISAQEQTFPCEFCGKTFKWRTSLRKHLETHRIETGEKRKPYCAPCRLSFTTTSNLQKHVRTSSKHQIQLKLRKLTESLPDLTGPDRHKAQLEIRTSVNKSRLQYPCTQCDKRFLWRGNLLRHMNSHAAKANGDLICKPCNRTFSSIATYQQHMKISKKHVSENDFKFMCSDCGKKFPTKSRLRDHINWEHLKNFVYSCDECQKVFKTSNSVYLHKQVHKKDVIEHLCDHCGKPFPSQAKLRSHILGLHSRAAPYRCPACGARFSWHSCLSRHVRQKHRRDDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01080133;
90% Identity: iTF_00986531;
80% Identity: -