Mcix003199.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melitaea cinxia
Gene Symbol
-
Assembly
GCA_905220565.1
Location
HG992231.1:9572030-9577585[+]

Transcription Factor Domain

TF Family
RXR-like
Domain
zf-C4|RXR-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers. Each zinc finger contains a group of four Cys residues which co-ordinates a single zinc atom. RXR functions as a DNA binding partner by forming heterodimers with other nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR. All RXR heterodimers preferentially bind response elements composed of direct repeats of two AGGTCA sites with a 1-5 bp spacer. RXRs can play different roles in these heterodimers. RXR acts either as a structural component of the heterodimer complex, required for DNA binding but not acting as a receptor, or as both a structural and a functional component of the heterodimer, allowing 9-cis RA to signal through the corresponding heterodimer. In addition, RXR can also form homodimers, functioning as a receptor for 9-cis RA, independently of other nuclear receptors. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, RXR has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [cite:PUB00121610], [cite:PUB00121611], [cite:PUB00121612], [cite:PUB00025660], [cite:PUB00121613], [cite:PUB00092048], [cite:PUB00092725], [cite:PUB00092726], [cite:PUB00016724], [cite:PUB00059514PMID:18971932
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 2.6e-05 0.1 13.2 0.0 93 115 8 30 6 55 0.83
2 22 0.00012 0.49 11.0 0.0 97 115 74 92 63 117 0.83
3 22 0.00012 0.49 11.0 0.0 97 115 136 154 125 179 0.83
4 22 0.00012 0.49 11.0 0.0 97 115 198 216 187 241 0.83
5 22 0.00012 0.49 11.0 0.0 97 115 260 278 249 303 0.83
6 22 0.00012 0.49 11.0 0.0 97 115 322 340 311 365 0.83
7 22 0.00012 0.49 11.0 0.0 97 115 384 402 373 427 0.83
8 22 0.00012 0.49 11.0 0.0 97 115 446 464 435 489 0.83
9 22 0.00012 0.49 11.0 0.0 97 115 508 526 497 551 0.83
10 22 0.00012 0.49 11.0 0.0 97 115 570 588 559 613 0.83
11 22 0.00012 0.49 11.0 0.0 97 115 632 650 621 675 0.83
12 22 0.00012 0.49 11.0 0.0 97 115 694 712 683 737 0.83
13 22 0.00012 0.49 11.0 0.0 97 115 756 774 745 799 0.83
14 22 0.00012 0.49 11.0 0.0 97 115 818 836 807 861 0.83
15 22 0.00012 0.49 11.0 0.0 97 115 880 898 869 923 0.83
16 22 0.00012 0.49 11.0 0.0 97 115 942 960 931 985 0.83
17 22 0.00012 0.49 11.0 0.0 97 115 1004 1022 993 1047 0.83
18 22 0.00012 0.49 11.0 0.0 97 115 1066 1084 1055 1109 0.83
19 22 0.00012 0.49 11.0 0.0 97 115 1128 1146 1117 1171 0.83
20 22 0.00012 0.49 11.0 0.0 97 115 1190 1208 1179 1233 0.83
21 22 0.00012 0.49 11.0 0.0 97 115 1252 1270 1241 1295 0.83
22 22 0.00012 0.49 11.0 0.0 97 115 1314 1332 1303 1357 0.83

Sequence Information

Coding Sequence
ATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGACTACACGCGCTCACTTACTTGTATACATATATATGTGGACCCCGCGGCGAGCGCGCTACCGCAGCGTGCTGGTGGACCCCGCGGAGTTCGCCTGCATGAAGGCCATCGTGCTCTTCAAGTCCGGTGA
Protein Sequence
MWTPRRARYRSVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVRVLVDPAEFACMKAIVLFKSGDYTRSLTCIHIYVDPAASALPQRAGGPRGVRLHEGHRALQVR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00985149;
90% Identity
iTF_00985149;
80% Identity
iTF_00985149;