Basic Information

Gene Symbol
ZNF831
Assembly
GCA_001276565.1
Location
KQ435700.1:296192-342686[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0065 0.55 10.5 0.3 2 22 424 444 423 447 0.89
2 12 0.00086 0.073 13.2 0.1 2 23 462 484 461 484 0.97
3 12 0.12 10 6.5 0.6 1 23 513 537 513 537 0.92
4 12 0.038 3.2 8.0 2.9 1 21 584 604 584 609 0.94
5 12 3e-05 0.0026 17.8 0.3 1 23 670 691 670 691 0.98
6 12 0.0004 0.034 14.3 0.1 1 21 697 717 697 718 0.95
7 12 0.27 23 5.4 1.5 1 17 745 761 745 762 0.93
8 12 6.9 5.8e+02 1.0 3.9 11 23 794 806 794 806 0.93
9 12 0.0022 0.18 12.0 0.0 1 23 811 836 811 836 0.94
10 12 9.4e-05 0.008 16.3 1.8 1 23 845 867 845 867 0.98
11 12 0.058 4.9 7.5 0.7 3 23 881 903 880 903 0.92
12 12 1.5 1.3e+02 3.0 0.4 1 14 909 922 909 924 0.85

Sequence Information

Coding Sequence
ATGGAAAGttacgaggacgacgacgacactCACTTCTGCATCAAATGCCACCTGACGATACACGGCCTGGAGAATTACGTTCGACATCGTCAATCGGGATGTCGGCCACCGGACGACAAGAACGTCGCGGCACGTGTGTCGCCGACGACGCCCGCCTCGCCGACCACCGTCTTCTACCCGGAGATACTCAACGCCGACGCGTTCTTCAGTTCGCTGGAGCTGCGTAGCAGCAGCAAGTCGAACACGCGGAAGGCGGCCGGCCTGCTCGAGGAGAGCAGGAAGTTCAAGAAGGAGGACAAACACCGGAAGAAGAGCCCGAAGGGCGCGCAGGTGGACAACGAGGACTCGGCGACGGTGAAGGAGAAGCTTCACAACATGCTGCCGGGCGTCGCCGAACTCGACGATCCAACGGACCATCTCTGCATGCCGAAGCGGCAGGACGACGCGCAGAGGATGGAGCATCACGTCCATCAGACCTGGCTGGAGGACACGATACTGGCCGAGCTGGTGGCGAACAACGAGAACAAGGAGCTGGGCAGATACGAGTTCGAGTATCAACAGGACGACGACTCGGAGGACGACATGCTGGAGGAAGATCTGGGGGAGGACGACGAGGGTGGGTCGTACTCGGAGTCGGACGACGGGGAGGACCGGCAACGTCCGCCGCGTGGTCACATCGGTGGCAAATGGAAGCCAGAATTGGACGATCTTCCTCAAAATATGTCTCAACTTCAGGACGACGACGCGGAGCCGGAGGACGAGCATCAAGAACATCCGCCGCCGACCTACACCGGGGGCAAGTGGCGACCCTCGGACGCGTCGCAGACTTGTTTTCGTCGCGAGGAAAAGATTTTAGACCAAAAAGCGGAAGAGTACGAGACTAAGAGCAACGTCGGTCAACCATCGCCGGGACACACGCGAGGGAAATGGGTACCGGGTGCACAAACGGATATCGAATCAGGATATTGGTGCAGTCCTTGCGGCAGAAAACTTGCCTCTCGATTGGTCTACAACAGGCATCTTCTCTCTGATTTGCACGCCAGAAGGAGCATTCGAGAAATCGATGACGTTCTTTCTCTGCCGCGTGCCGCGAGACTGACGGATATCTGTGCTCGGTGTATCGGCGGTAGCTACAGATGCACCCCCTGTGACTTTTGGTGCGAGGATAACGAGACGATGGACTCGCACCTGCTCGAGCGGAGCCACCGCGACGTCGTCTCGATGATGAATGGCTCGGTGCCGATCATGATCGGTCGTCAGCGAGCGCTGCCCTGCGCCAGCTGCGATCGCCGATTCCGCTACAATTTGCAACTTCGGCTGCACGTGAGGGAGAGCGGCCACGAGGAGAGCCTGACCGCGACCGATGAGTATCAGCAGCGAATCAAATGCAATCTATGCCCGCAAATTGTCCGATCGTTGGTGGCACTTCAGCGTCACCAGTTGACCGCCCATGTCGCGAGAGGGATCGCGAAGAAAGACGAGGGGACGAGCGGGACGAACGCGGGGCAGCAGCCTTCGCGATCAGCCTCGACGCCTTATTTCTGCTCGTTTTGCTCGATGAACTTTGCCACTGCCCAGGACGCTGTCTTGCACCGGAGGACGTCCAGTCACAAAGAGATCGTCAAAGCTCGGAAAAGCAACGACAGCGCGGCGATGTCGACGACACGCGAGTGCCCCCACTGCAAGCAGAAACAGGCGAATCTGTTCGAGCACAAGAAACATCTTCTCGACCAGCATCCCGAGCTCTGTCACAGATGTCCCAAATGCGGGACGTTGTTCGCCCTCTCGCAAGACGTGACGAGACACACGAGAGAGAACAAATGCCACGGCGCAGCCGGCGAATTAACCAAAACGAGGACGTCGAACCCGAAAGACGAATGGAAATGCGGCAGCTGTAGCTTCTCGAGCAACTCTCAGGCGGAATTTATCTTTCACGGGGCTCTTCACGCGGGGGCCGTGCGGAACGACAACGAGGAGGACGGGAACCCTGGCAAATCGCTGGCCAAATATTCCTGCCCCATTTGCAAGAAGGCGTTCGCGAAAGTGTCATTACGGAATCACATCAGGAGTCATACCGGGGAACGACCGTTCCCCTGTGCCAAGTGTCTCGTGGCCTTCTCGAGAAGATCGGACCTAAACGCCCATCAGAAAGAATGCACCGGCTCGGCGGTGgcgtcgtcctcgtcctcgtcctcgtcagCCTGGACGAACGAATCTGGAAGGAAACGATGCTTCTCCTGCTCCGAGTGCAACAGCGCTTTCTACACCAAttttaatctatttaaTGGCCCAATTTGCAAGATTCTTGGAGTTACTGTTGATACtgctaaaaattCGATTTTCAGCTCCTCACAAgtgcataaaaaaaataagcagCCTACaaataaGCATTCGCTGCGGCAGCACATGTTGCGACACGCTGGCAAGAACTACAAGTGCGGACTTCCGGGCTGTCCAACGGTGCTCCGGACGGCCTCCGAATTGAGATCGCACAGAAGCTTGGTACACGACAGCACGCCGTCTAATAGGCAGTACAAGTGCTCGGATTGCTCCTACGCGGCGAAGACGAAGACCCAGCTACGCCGGCATCGTGCACGACACGACGAGCCAGAGGACACGGGGAAATCGGAACTCCGCGCATGTCCCTACAGTGGCTGCGCTTTCAAAACGAAACTCGCGTCTCATTTGCAGCGGCACGTGCGTCTCCACACGGGTACAAAGCCTTACAAGTGTCGTCATTGTCCGTACGCGAGCAACAACTTGAGTTCAAGATATACAAGTTTAGTCtcaaacattcaaaataaaaaaaaaacaccattATTATGGTATTTTCATGATCCGCTATATGCAGTTTCAATTAAtcgcaaaaatttgaaagatttgccAACTGACAATTGTTGCGAAGAAGTTATTTCACAGTTTCGTAACGATGTACTAATGAAGCAATAA
Protein Sequence
MESYEDDDDTHFCIKCHLTIHGLENYVRHRQSGCRPPDDKNVAARVSPTTPASPTTVFYPEILNADAFFSSLELRSSSKSNTRKAAGLLEESRKFKKEDKHRKKSPKGAQVDNEDSATVKEKLHNMLPGVAELDDPTDHLCMPKRQDDAQRMEHHVHQTWLEDTILAELVANNENKELGRYEFEYQQDDDSEDDMLEEDLGEDDEGGSYSESDDGEDRQRPPRGHIGGKWKPELDDLPQNMSQLQDDDAEPEDEHQEHPPPTYTGGKWRPSDASQTCFRREEKILDQKAEEYETKSNVGQPSPGHTRGKWVPGAQTDIESGYWCSPCGRKLASRLVYNRHLLSDLHARRSIREIDDVLSLPRAARLTDICARCIGGSYRCTPCDFWCEDNETMDSHLLERSHRDVVSMMNGSVPIMIGRQRALPCASCDRRFRYNLQLRLHVRESGHEESLTATDEYQQRIKCNLCPQIVRSLVALQRHQLTAHVARGIAKKDEGTSGTNAGQQPSRSASTPYFCSFCSMNFATAQDAVLHRRTSSHKEIVKARKSNDSAAMSTTRECPHCKQKQANLFEHKKHLLDQHPELCHRCPKCGTLFALSQDVTRHTRENKCHGAAGELTKTRTSNPKDEWKCGSCSFSSNSQAEFIFHGALHAGAVRNDNEEDGNPGKSLAKYSCPICKKAFAKVSLRNHIRSHTGERPFPCAKCLVAFSRRSDLNAHQKECTGSAVASSSSSSSSAWTNESGRKRCFSCSECNSAFYTNFNLFNGPICKILGVTVDTAKNSIFSSSQVHKKNKQPTNKHSLRQHMLRHAGKNYKCGLPGCPTVLRTASELRSHRSLVHDSTPSNRQYKCSDCSYAAKTKTQLRRHRARHDEPEDTGKSELRACPYSGCAFKTKLASHLQRHVRLHTGTKPYKCRHCPYASNNLSSRYTSLVSNIQNKKKTPLLWYFHDPLYAVSINRKNLKDLPTDNCCEEVISQFRNDVLMKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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