Basic Information

Insect: Melipona quadrifasciata
Gene Symbol: lola
Assembly: GCA_001276565.1
Location: KQ435783.1:594608-623761[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00046 0.039 14.1 1.8 1 21 33 53 33 54 0.96

2 16 9.3e-05 0.008 16.3 3.2 1 23 62 85 62 85 0.98

3 16 0.00012 0.0099 16.0 1.6 1 21 174 194 174 195 0.96

4 16 0.011 0.89 9.8 2.4 1 21 260 280 260 281 0.94

5 16 0.00061 0.052 13.7 9.3 1 20 361 380 361 381 0.95

6 16 0.0088 0.74 10.1 2.7 1 23 390 413 390 413 0.95

7 16 0.0036 0.3 11.3 1.6 1 20 486 505 486 507 0.93

8 16 0.1 8.8 6.7 3.3 1 21 529 549 529 550 0.94

9 16 9 7.7e+02 0.6 1.8 1 11 558 568 558 571 0.82

10 16 0.00018 0.015 15.4 1.9 1 22 726 747 726 747 0.96

11 16 0.001 0.087 13.0 0.6 3 21 773 791 771 792 0.95

12 16 0.0076 0.65 10.2 0.2 1 23 800 823 800 823 0.97

13 16 5 4.2e+02 1.4 0.4 1 8 871 878 871 880 0.87

14 16 0.0028 0.24 11.6 0.8 1 20 920 939 920 941 0.93

15 16 0.0019 0.16 12.2 0.7 1 23 952 975 952 975 0.96

16 16 0.15 13 6.1 6.4 1 23 982 1005 982 1005 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00046	0.039	14.1	1.8	1	21	33	53	33	54	0.96
2	16	9.3e-05	0.008	16.3	3.2	1	23	62	85	62	85	0.98
3	16	0.00012	0.0099	16.0	1.6	1	21	174	194	174	195	0.96
4	16	0.011	0.89	9.8	2.4	1	21	260	280	260	281	0.94
5	16	0.00061	0.052	13.7	9.3	1	20	361	380	361	381	0.95
6	16	0.0088	0.74	10.1	2.7	1	23	390	413	390	413	0.95
7	16	0.0036	0.3	11.3	1.6	1	20	486	505	486	507	0.93
8	16	0.1	8.8	6.7	3.3	1	21	529	549	529	550	0.94
9	16	9	7.7e+02	0.6	1.8	1	11	558	568	558	571	0.82
10	16	0.00018	0.015	15.4	1.9	1	22	726	747	726	747	0.96
11	16	0.001	0.087	13.0	0.6	3	21	773	791	771	792	0.95
12	16	0.0076	0.65	10.2	0.2	1	23	800	823	800	823	0.97
13	16	5	4.2e+02	1.4	0.4	1	8	871	878	871	880	0.87
14	16	0.0028	0.24	11.6	0.8	1	20	920	939	920	941	0.93
15	16	0.0019	0.16	12.2	0.7	1	23	952	975	952	975	0.96
16	16	0.15	13	6.1	6.4	1	23	982	1005	982	1005	0.98

Sequence Information

Coding Sequence: ATGCCGAAGAACTTTCAAAGGAATTGCAACTACCCGATGATGCCTCTGATCAAGGACCTGGCGACTCTTTGGATGGCGAAGCGAGTCGAGTTCCCATATCGGTGTGAGACATGCGGGAAAGGGTATCAGCATCGCGCCACCCTGGTCAGGCATACCAGGCACGAGTGTGGCAAGGAACCGCAGTTCAAATGCCCCTATTGTGCCCACAGAACCAAACAACGCGGCAATCTTTATCAACACATTCGAACCAACCATCCTGGCAAGAACGTGTTTTCGAATTTCACGAGCACGAGCAAAATCAGGGAAGAAGGAATCGGCGAACGCATGGAGTTACTCGATGCGACCGACGCTTACGTTGTAAACACGCGGATTAATTTTGGAAACGAAAGTGCCAAAACGTGTACAGACGACTGTGTCATAATCGAAGACGCTTGTGAGAAtgaagacgaagacgacgacgagacTGAGAGCATCGAATGTGCGGCAGGTGGCTTCAAAGAAGATAGGCAACAGTACAAGTATTCGTGTACGAAGTGCTTGAAaagttacaaaagaaaaggTCATCTGGTGGaacatcaaaaaatattttgtggcAAGGACAAACAGCAGTGTGAACTGATCCTTTGGGAGGACTATCAGATATTCGAGCCTACGACGGTAACCGAAGCGAGCGAGTTTCGATCGGAAAGTTGCTCTTACGAAGCGAATTATTTCGGGTCTGATCGTAAATCTACCCGAATATTCAGAAACAAAAGCACGGATCCCCTCGGAGGCAGATACAAGTGTTCGAAATGTTCGAAATCGTATCGTTGGAAACATCATTTGGTGGAACACGTGAAAGCGTCTTGCGGCCAGAAGAAGGCCGAGTGTTGCCCTTATTGGCGAAGGTGTTACACCAAAAGATCGAGTTTCTCTGGACGGTTCGTGAGATctgaaattgatattgaacGTATCAAGTTAGCTGTTGAAGCGGTGGCCAGTGGATTATCCTTGAGGAAAGCAGCTGAAAAATTCTCTATATCCAAGTCTGTTCTTCATCGTTACATGGAGTGCCAGTATCCTGTGATTTCGGTGTTCAAGCATACCTGTACTACTTGCGGAAAAACGTACAAACACAAACATCATTTGAAGAGGCATCACGATTTCGAGTGCGGCATTGATCCAAAGTTCAAATGCGCCTTTTGTTCGCATAGAACTCGGTATAAGGATAGTCTGATTAAGCACATACTGGCGAGACATCGACTATTTCTCGATCAGAATCCACGCTACAGATTGCAACAGGTGAACGCCCTTGCCGATGTCGAGGATACACAGAATTACAGCTCGTCTAATTGGACAGTGCTGACATTGCCAACGATGTCGACAATACCGAGCAATCCCGTCACCTGTACTAGACATCTCCGATCCATGACGCTGAAGGATCAGGACAAGATGCGCAGATATGGTCCACGAAAGTATCTTTGCACCGATTGTAATCGTTGCTTTGCCTTAATGGCCTCGTTGAAACGTCACAGAAGCTTCGAGTGTAACTTGTTGTCGACTGTTATGGGAAAGGCCGAACAGGAAAGAAGACGGAAGAAAAAGCATACCTGCCCTAATTGCAGTCGTAGCTACCAGTTGTGCACGTCACTTTGGAGACATCGGAACTACGAGTGCGGCGTCGAGCCCAAATTCAGTTGTCCCATTTGCAAGACCAAAACCGCAAATTGTCGCATGGGGATCCAGAAACGGATGCTTCAGAAGTGTGGAATCGTTCACCTGTCATCAATGCGGCAGATCGTATCAAATGAGGCACAATCTGGTGAAACACTTGCGATTCGAGTGCGGTGGCCAGAAGCATTTTGCGTGCAATCTATGCCCGGCGAGATACACGCAGAACGGAAAGCTAAGGCAACACATgGCGTCGACGGCCAGGAGATGGAAAAACACTATCTCTgggaggatcgatcgatcgatcgatcgattctccCAGATCAGAAATCAAATGGAAAGGCCTTGTGGTTCATCGagAGCAAACCGGATGACCAAATGTACCTAAAGTGTCTGCCGCTAATCGATGTCCAGAACAACGCGGATCCATTCAGTCCAGGTGTGAGTCCCGGGTATCAGAATCTCCTCTTCGAGGAGATTGGATATCGGAATTCTCAACAATGGATGCCAGAAACGGATAAACCTTTTATGTGTTCGAACTGTGGGAAAGGATACACTCACGTGTTCACCCTGAATCGCCATCGTCGGACAGTTTGCGTCAAAGGTCTACTTTTTTGCGATCGGCTGCCACGTGCAATTTGGAGACGTTGCAGGGACGATCTTCTTTGTTTGAAGTGTGCAAAGAAATACAGCGATTGGAGAAGTTTGCGGAAACATATGAATTTTTTCTGCCAAATGGAACCGCTTTATCCTTGTCCTTATTGCAGCTACAGGGCTAGAATACCAACTCTACTCAAGTATCACGTCAGGCGTGAGCACGTAGTTTTCGCATCAtatgtgtatatatatatgtatatatatatatatactgaatatatatatatcttttgtaAAAGGGCTGATTTATCAAGCCAACAGTTGGATGACTCGCTGATGCCGGACCAATCTGGCAAACCTGTCTTTGTCTGTCCGAAATGCAGCAAAAACGTTTGGAACGTACAAGGTTACATGACCAATTACGGCCCCGTTGATGGTCTACAACTTCCTCCggaattcgataaatttaagaTATCTGCTGCACAATCTTTGTTGAACCATCACAAACGACATATGTGCGGCTTTTGTAAGAAGGTCTTTCCTTTGAAGAACTTGTTGAGAAGGCACGTGCAATTTGGCTGCAAGATGAATCCCAGAAATTCACAATTTGCTTGTTCGTTCTGCCCGTACAAGAGCACCTACAAAGCGAACATGGAAAGACACGTGCGAAACGTTCACGACACCGGCGTGCTAAAATTTCGTTGTGATCTGTGCAACTTCCGTAgcaattattcattttgtGTGAGAAGGCATATGAAGACTTTCCATCGCACGGTCgactcgaacgaaacgaggaaaTAcCTTCAGTCGTTTATCCATGTGGTTCCTGCGGCAAGACGTTCAAGTGGAAGAAAAGCTTGGTGCGGCACGAGCGAGAAGAGTGTGGAAGGAAGCAGTATCAGTGTCCTCAGTGTCTTCGCCTGA
Protein Sequence: MPKNFQRNCNYPMMPLIKDLATLWMAKRVEFPYRCETCGKGYQHRATLVRHTRHECGKEPQFKCPYCAHRTKQRGNLYQHIRTNHPGKNVFSNFTSTSKIREEGIGERMELLDATDAYVVNTRINFGNESAKTCTDDCVIIEDACENEDEDDDETESIECAAGGFKEDRQQYKYSCTKCLKSYKRKGHLVEHQKIFCGKDKQQCELILWEDYQIFEPTTVTEASEFRSESCSYEANYFGSDRKSTRIFRNKSTDPLGGRYKCSKCSKSYRWKHHLVEHVKASCGQKKAECCPYWRRCYTKRSSFSGRFVRSEIDIERIKLAVEAVASGLSLRKAAEKFSISKSVLHRYMECQYPVISVFKHTCTTCGKTYKHKHHLKRHHDFECGIDPKFKCAFCSHRTRYKDSLIKHILARHRLFLDQNPRYRLQQVNALADVEDTQNYSSSNWTVLTLPTMSTIPSNPVTCTRHLRSMTLKDQDKMRRYGPRKYLCTDCNRCFALMASLKRHRSFECNLLSTVMGKAEQERRRKKKHTCPNCSRSYQLCTSLWRHRNYECGVEPKFSCPICKTKTANCRMGIQKRMLQKCGIVHLSSMRQIVSNEAQSGETLAIRVRWPEAFCVQSMPGEIHAERKAKATHGVDGQEMEKHYLWEDRSIDRSILPDQKSNGKALWFIESKPDDQMYLKCLPLIDVQNNADPFSPGVSPGYQNLLFEEIGYRNSQQWMPETDKPFMCSNCGKGYTHVFTLNRHRRTVCVKGLLFCDRLPRAIWRRCRDDLLCLKCAKKYSDWRSLRKHMNFFCQMEPLYPCPYCSYRARIPTLLKYHVRREHVVFASYVYIYMYIYIYTEYIYIFCKRADLSSQQLDDSLMPDQSGKPVFVCPKCSKNVWNVQGYMTNYGPVDGLQLPPEFDKFKISAAQSLLNHHKRHMCGFCKKVFPLKNLLRRHVQFGCKMNPRNSQFACSFCPYKSTYKANMERHVRNVHDTGVLKFRCDLCNFRSNYSFCVRRHMKTFHRTVDSNETRKYLQSFIHVVPAARRSSGRKAWCGTSEKSVEGSSISVLSVFA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00983538;
90% Identity: iTF_00983538;
80% Identity: iTF_00983538;