Basic Information

Insect: Melipona quadrifasciata
Gene Symbol: topi
Assembly: GCA_001276565.1
Location: KQ435798.1:223505-225593[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.58 50 4.3 4.3 1 23 89 111 89 111 0.89

2 15 0.037 3.2 8.1 1.1 2 23 118 140 117 140 0.95

3 15 0.001 0.088 13.0 0.4 2 21 147 166 146 167 0.92

4 15 0.00026 0.022 14.8 2.4 1 23 174 196 174 196 0.97

5 15 2.5e-07 2.1e-05 24.4 1.0 1 23 202 224 202 224 0.95

6 15 0.079 6.8 7.0 6.5 1 23 273 295 273 295 0.97

7 15 0.0011 0.094 12.9 0.9 1 23 301 323 301 323 0.95

8 15 0.0074 0.63 10.3 0.7 1 23 333 356 333 356 0.94

9 15 0.31 26 5.2 0.0 1 20 370 389 370 391 0.91

10 15 0.0026 0.22 11.7 0.1 1 23 396 418 396 418 0.98

11 15 1.2e-06 9.9e-05 22.3 3.1 1 23 424 446 424 446 0.98

12 15 7.5e-05 0.0063 16.6 0.4 1 23 452 475 452 475 0.97

13 15 0.028 2.4 8.5 0.7 1 23 481 503 481 503 0.89

14 15 1.9e-07 1.6e-05 24.8 2.2 1 23 509 531 509 531 0.99

15 15 9.1e-07 7.8e-05 22.6 3.0 1 23 537 560 537 560 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.58	50	4.3	4.3	1	23	89	111	89	111	0.89
2	15	0.037	3.2	8.1	1.1	2	23	118	140	117	140	0.95
3	15	0.001	0.088	13.0	0.4	2	21	147	166	146	167	0.92
4	15	0.00026	0.022	14.8	2.4	1	23	174	196	174	196	0.97
5	15	2.5e-07	2.1e-05	24.4	1.0	1	23	202	224	202	224	0.95
6	15	0.079	6.8	7.0	6.5	1	23	273	295	273	295	0.97
7	15	0.0011	0.094	12.9	0.9	1	23	301	323	301	323	0.95
8	15	0.0074	0.63	10.3	0.7	1	23	333	356	333	356	0.94
9	15	0.31	26	5.2	0.0	1	20	370	389	370	391	0.91
10	15	0.0026	0.22	11.7	0.1	1	23	396	418	396	418	0.98
11	15	1.2e-06	9.9e-05	22.3	3.1	1	23	424	446	424	446	0.98
12	15	7.5e-05	0.0063	16.6	0.4	1	23	452	475	452	475	0.97
13	15	0.028	2.4	8.5	0.7	1	23	481	503	481	503	0.89
14	15	1.9e-07	1.6e-05	24.8	2.2	1	23	509	531	509	531	0.99
15	15	9.1e-07	7.8e-05	22.6	3.0	1	23	537	560	537	560	0.97

Sequence Information

Coding Sequence: ATGAGAGTTTATAAAGAGAATAAAGAAACTGGGAAAGATGTTGAATTATACGACAGCGATATTGTTCTTGAAAGCAGCGACGAGGAACAAATTCCCAATCAAATTAAGATCGACGAAGAACCAAAAAACAAGTCTATAACTCTATTTTGCTTGGGAACtaagcaaaaatatttgaaatgtggCGCTTGCATGAATTTGTACCATACTAAAGAAACTCTGGACGAGCACAAATGTAAACCTAATTTACAGTGTACTTCCAAACCTTACAAGTGTAACATTTGTTTTGCAACTTTCACGTTCGAAGAACGGTTGCAGTTCCATCAACACTTTCACAAAGATGCAAAAGCATTGTATTGCGAAATTTGCAAGATTACATTTGGCAAGgagttaaaattgttttatcattaCAAAAGgTATCATTGCAAAGATGGTAGAGTATCTTGTTTGCAATGTGGAAAGCTGTTTGAAAATCAAGAAGGATTGAAAAAACATGTGTGCGTGGATGGCAAGACAAGACCTCATGTGTGCGAAGTCTGCTCTAAAGGGTTCTGCGATGGATACACTTTGAAACGTCACGTGGTAACTCACCTTCCGGAAAAGCCGTACAAGTGTCCAGAATGTTCAAAGAGTTTTACACAGAAATCAAGATTGAACAAACACGTTGCTGGGCACAGcatcatttttgaaaacaatcaGACTATTTGGAGATGTATTCGTTGCGGTGAAGCCTTCGGAAGTTGCGAATTTGCGGATGAACACTGCCAAAAACACGAGGAAAAAATTAGTCTTATAGAGGAGATGCAAGTATTGAAACTGTACCATTGTGAATTCTGCAGTAGCCACTTTGCAGACATGGATCATTTGAAAACCCACAGAGAATCGCACGTTATCGAGAAACCGTACTCCTGCAATCATTGTAACACTGTATTCAAATCTTACGCGGAGGCTGTTCTTCACTGGAAAGAACACCCAAGAATATTCAAAGTGTTAGTGGTATTTTTATGCGAGATCTGCGACAGAGACGTTAAAGAACTGTCCCTGCTTTACAAGCACAAACAAAAAAGGCATCAGCCGTTGCCTAGGAGATCAgagaagaacaaagaaaaattcatttgtgaACTCTGTGGAAGTATTTTCATGAGTATTGAAGATTTTCAAGAGCACGGGAAATACAGATGTTCCAAATTCCCGTGTGATATTTGTGGCAGTCTATTGCCGACTGCAAATTCTTTGAATGCTCACAAAAGAAGGCACAGCGGATTAAGACCATACGTTTGCAACATCTGTGGTAAAAGCTACACTCAGTCTAGCCACATGTGGACCCACAAAAGGTTCCACATGGGCGTGAAACCTTATGCCTGCGAATACTGTGATCAAAGATTCACAATAAAGCCAGACCTGGCGGATCACACCAGAAAGAAACATACAAGGGAAAGACCATTCAAATGTGATGTTTGCAACAAAGCTTTCCTCACTGGCTCTGTTTTCTACCAGCACAGGCTAATACACAGAGGAGATCGTAGGTACAAGTGTCACTACTGCGAGAAAGCATTCACCAGAACGGAAGCTTTGAACAACCATATAAAGATTCACACTGGTGAAAAGCCACACGTGTGCGACGTTTGTGGCAGACGCTTCAGACAGAAGGGGGATATGAGAAAGCACAGGCGAACGCAGCACGTTGCCAAACAAGATACAAAATAG
Protein Sequence: MRVYKENKETGKDVELYDSDIVLESSDEEQIPNQIKIDEEPKNKSITLFCLGTKQKYLKCGACMNLYHTKETLDEHKCKPNLQCTSKPYKCNICFATFTFEERLQFHQHFHKDAKALYCEICKITFGKELKLFYHYKRYHCKDGRVSCLQCGKLFENQEGLKKHVCVDGKTRPHVCEVCSKGFCDGYTLKRHVVTHLPEKPYKCPECSKSFTQKSRLNKHVAGHSIIFENNQTIWRCIRCGEAFGSCEFADEHCQKHEEKISLIEEMQVLKLYHCEFCSSHFADMDHLKTHRESHVIEKPYSCNHCNTVFKSYAEAVLHWKEHPRIFKVLVVFLCEICDRDVKELSLLYKHKQKRHQPLPRRSEKNKEKFICELCGSIFMSIEDFQEHGKYRCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHVCDVCGRRFRQKGDMRKHRRTQHVAKQDTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: iTF_01419143;
80% Identity: -