Basic Information

Insect: Melipona bicolor
Gene Symbol: mecom-b
Assembly: GCA_030673865.1
Location: JAHYIQ010000003.1:11059249-11065223[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0062 0.68 11.1 0.3 2 23 51 73 50 73 0.94

2 9 0.46 51 5.2 0.1 1 23 80 103 80 103 0.93

3 9 1.5e-05 0.0016 19.3 1.8 1 23 109 136 109 137 0.93

4 9 3.9e-06 0.00043 21.1 2.6 1 23 143 165 143 165 0.95

5 9 2.4e-05 0.0027 18.6 5.0 1 23 171 193 171 193 0.99

6 9 0.00018 0.019 15.9 0.7 2 21 201 220 200 221 0.95

7 9 5.7e-09 6.2e-07 30.1 1.2 1 23 572 594 572 594 0.99

8 9 3e-07 3.3e-05 24.7 1.7 1 23 600 623 600 623 0.97

9 9 8.4e-06 0.00092 20.1 3.4 1 23 629 651 629 651 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0062	0.68	11.1	0.3	2	23	51	73	50	73	0.94
2	9	0.46	51	5.2	0.1	1	23	80	103	80	103	0.93
3	9	1.5e-05	0.0016	19.3	1.8	1	23	109	136	109	137	0.93
4	9	3.9e-06	0.00043	21.1	2.6	1	23	143	165	143	165	0.95
5	9	2.4e-05	0.0027	18.6	5.0	1	23	171	193	171	193	0.99
6	9	0.00018	0.019	15.9	0.7	2	21	201	220	200	221	0.95
7	9	5.7e-09	6.2e-07	30.1	1.2	1	23	572	594	572	594	0.99
8	9	3e-07	3.3e-05	24.7	1.7	1	23	600	623	600	623	0.97
9	9	8.4e-06	0.00092	20.1	3.4	1	23	629	651	629	651	0.99

Sequence Information

Coding Sequence: ATGGAGGAACGATTAACGTTCTATGGGGGGGTTGGATGCGTGGTGAAGGGCGTAGTTGGTGGCATAGGGGCTGTGCCCGGTTCCCATGAAGCCTCGCAACATAGTGGCACCGTAGACGAGGATAAAGAGGACGAGGAGGAAGGCGAGACCAGGTGTCCGGTCTGCGACAAACCGTTTCAAGACATTGAACTGTTGGATAGTCACGTGGTTACCTGTCACAGATACCCAGCGGAACAGCATCGCTGCGACAGCTGTCCTCGTGCGTACGCCTGGCGGCCACTGCTGGTTCGTCACCGTGCGATCGTTCACGGTGATCTCCGGAACTACCCCTGCGAGAACTGTCCAAAGTCGGACAAACCGCAGGTCTTCACGGACCCGTCGAACCTGCAGCGACACATCAGGACCCATCACGTGGGCGCGAGGAGTCACGCGTGCACTGAGTGCGGGAAGACGTTCGCCACCAGTTCCGGCCTTAAGCAGCACACCCATATCCACAGCAGCGTGAAGCCGTTCCAGTGCGAGGTGTGCTTCAAAGCGTACACTCAGTTCTCAAACTTATGCCGACACAAACGCATGCACGCGGATTGCCGTATGCAGATCAAGTGCGTTAAATGCGGACAGTCGTTCAGCACGGTCACTTCGTTAACAAAGCATAAGCGGTTCTGCGATTCAACGCCGCCAACCGGTCCACCCGGCGCGATGCCACAATTACCGACTCCGGCGCCCAGCCCATTTCTCGTCTATCCTAGACCTCCCGTCAGTCTCCCGGGAGGCTTACCTTTCTATCCGCCTAGTCTAATGGGACCGTATCCAGGAATTTTTCCAAATGCGTCCAATTTCTTGAACACTCCTCTGCTGTTTCCTCCAAAAATCGAGGAAGCTGAGAAGAGATGCGACAGTCCAAAGAAAGAACGCTTCACTCCGCCGAGGGTTCTGCCGCAACATAGCAAGATATCACCCTCAACGGCCGAGGAAGCTACGTCCTCCTTCAGACCATCCCCGGCTAGGCCACCCGTTCAACCAACCCCGGAGAGCGACGACGATCCTTCCAAGAAACGGGAGAAAGACAGGAGCAACGAGAAGAAGGCGGATCCGGAAAATGTATCGAAAACTACGAACGAAGAGACAACGGATCAGCCTTTGGATCTGAGAGtgcaaacaaagaaacaacgaACGAATGTGAACGTTACCAACAGAAAGAGCCCGTCACCAACGCCAGCACCGATGGAGGAAGTTCCAGCTCCTCTGGATCCTCCGAAACCGGAAGAAGAAACGTCCATGCTGATGGAAGTGGATTCCAAGGACGTGGCCAGAAGTcctcaattaaaaattagctTACCCGCAGAACAACCGCCTACTAGTACGCCGCACATGGCGTACCCCAGACCGATTCATCCGATGTTTCTGGAGGCCATGTATCGCGGACCAACGAGTTCCTTCCCAGGATTTCCAGGCGGACCACCGCCTCCTGGAAGCGGAACGGAACCGAGACTCTTGCCACCGTTACCACCGTTCGGGACACCGCGTGGACTTCCTTTTTTAGGAACACTCATGAACGGGCTCAACAGCACTAGGCCAGGAAGCGGGGGATTCGACCTGCTTGCCAGGCCGCCACTAGGACCGTTCCCCGGCGTGAAACCCTTTCAGGACACCGTGATTCCACCTCAccatcatcaccatcatcatcacGCTCACGGCAAAATGAAAGACCGATATTCCTGCAAGTTCTGCGGCAAGGTATTCCCCAGATCCGCCAATTTGACGAGACATTTACGCACGCACACCGGCGAACAACCTTACAAATGCAAGTACTGCGAACGGTCCTTCAGCATCTCTAGCAACCTTCAGCGGCACGTAAGAAATATCCACGACAAGCAGAGACCGTTCAAGTGTCCACTCTGCGAGAGATGTTTTGGCCAACAGACGAATTTGGACAGACATTTGAAGAAACACGAAGCTGACGACGGCAGTGGCGTTGTTTCCGTGGCGGATTCACCGGGGAGCAGCAATGAAAATGAACGGGAGGACACGTATTTTGACGAAATTAGGTCGTTCATGGGGAAGGTGACTTACGGCGGTGAGGCTGGCTACGGATTACCCCCTCACCCGGCCTATTTGCCCAGTAGATTGCACGAGATTCACGAGTCCAAGATGGAAACCGAGTACGACGAAGACGAGGATAGCGAGGAAGGAGTCTCTCCTTTGGATGAAGCGGATGGCTTGTCGCCTGCAGAAGCCAAAGAATCGACTCCACCACCGCAGTATGATCTGAAGCTGAGGGAGAAGCAGGAATTGCTTAACAATAACACGGCCGAGCCAGTTATCGAGATTTCGACATAG
Protein Sequence: MEERLTFYGGVGCVVKGVVGGIGAVPGSHEASQHSGTVDEDKEDEEEGETRCPVCDKPFQDIELLDSHVVTCHRYPAEQHRCDSCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLTKHKRFCDSTPPTGPPGAMPQLPTPAPSPFLVYPRPPVSLPGGLPFYPPSLMGPYPGIFPNASNFLNTPLLFPPKIEEAEKRCDSPKKERFTPPRVLPQHSKISPSTAEEATSSFRPSPARPPVQPTPESDDDPSKKREKDRSNEKKADPENVSKTTNEETTDQPLDLRVQTKKQRTNVNVTNRKSPSPTPAPMEEVPAPLDPPKPEEETSMLMEVDSKDVARSPQLKISLPAEQPPTSTPHMAYPRPIHPMFLEAMYRGPTSSFPGFPGGPPPPGSGTEPRLLPPLPPFGTPRGLPFLGTLMNGLNSTRPGSGGFDLLARPPLGPFPGVKPFQDTVIPPHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEIHESKMETEYDEDEDSEEGVSPLDEADGLSPAEAKESTPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539779;
90% Identity: iTF_00118172;
80% Identity: -