Mpro031793.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melinopterus prodromus
Gene Symbol
ZEB2
Assembly
GCA_964023965.1
Location
OZ030394.1:10784343-10787153[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 4.1 4.1e+02 3.4 0.1 3 17 46 60 44 61 0.90
2 15 0.00042 0.042 15.9 1.9 2 20 204 222 203 225 0.92
3 15 0.0027 0.27 13.4 0.3 1 23 233 255 233 255 0.99
4 15 3.8e-05 0.0038 19.2 0.8 1 23 261 284 261 284 0.95
5 15 0.00068 0.068 15.3 1.7 1 23 290 312 290 312 0.97
6 15 0.00017 0.017 17.2 0.1 1 23 319 341 319 341 0.98
7 15 3.8e-06 0.00038 22.4 1.2 1 23 347 369 347 369 0.99
8 15 0.029 2.9 10.2 0.5 1 23 505 528 505 528 0.95
9 15 7.4e-05 0.0074 18.3 0.8 2 23 534 555 533 555 0.97
10 15 0.00048 0.048 15.8 2.2 1 23 563 585 563 585 0.99
11 15 5.2e-07 5.2e-05 25.1 2.2 1 23 591 614 591 614 0.98
12 15 3e-05 0.003 19.5 0.1 1 23 620 642 620 642 0.98
13 15 6.8e-05 0.0068 18.4 0.5 1 23 649 671 649 671 0.98
14 15 2e-06 0.0002 23.3 0.2 1 23 677 699 677 699 0.98
15 15 1.3e-05 0.0013 20.7 3.7 1 21 705 725 705 726 0.96

Sequence Information

Coding Sequence
ATGCCTCTCATATGCAGGCTATGTCTAAAAACGAATTTAGAAAATTACAACAGCGTAGACGTGGATGATACTCgacttaaaatattatcaataattcCGGAGATTgaTATCGACATAGTAGACAGGCCTGTAATATGTTCCGATTGTTCCGAAGTCCTAACAACCGCGTACAGTTTCaagcaaaattgtttgaagatAGAAGAACGAATAAACATGTATACAGGGAACGTTGTAAGCAAAATAATACTAGAAAATTTTTTGGAGTTGTACAATCATACAGAAAACAAAGAAGTAAAAGAAGAAAAACCCAAAGAAATTTTGTACGAGGTGGATTGCGAAGCACTGCTTGAAGACGTTAGTCCCGAGAATAACACCGTCGACgtagaaacaataaaaatcgaAGAAAATCCTAGAGAAACAATCGTAGAAAAGACTGTGTGTAAATTCTGTAATAAAAAGATTACCCGTACAGGAAAGCAATGGGTCTATCATATAGGAaaacatataaaaacaaaatacatttgttTCATATGTTGCGAAGGTTTTAACTCAAAATGGGAATACGTTTCACACAAGACCGAAAAACATGGACGTATACCAGGTACAACTAGATGCCACATATGCAATAAGGAGTTTTCGTCCACAGCCAACATGAAAAAACATCTACCTAtgcataaaaaaaagaaagcacCAGCTTTTCAATGTGATGTGTGCGGGTTAAAAGTAAAGCAATACGCGATACTACAGACGCATCTTCGCACTCATAACGGAGAACGTCCATTTAAATGCAAGTTCTGCGAAAAAGCTTTTGCTCAATCTAGTACACTATCGACCCACGTTAAAGCTGTGCACATGACTGAACGTCCATACATTTGCGAATTTTGCGGTAAGACGTTTGCAACAAACAGCGATTGTTCGTCTCATGTGAAGGTACATAAAGATATCGAGAAGAACTATGTTTGTAGTATTTGCGGGAAAGCATATGATGTTGCAAATAAGTTGGATTTACACATGAAGCGACATAATGGTGTCAAAGATTACGTTTGTGAGATTTGTAGTAAAGGTTTTGTCAATCGTCACGGGTTAAACAGACATGTGAGAAGGCATAATGAAGATAAACAGTTTGAATGTCATgATATCGATGTTGTAGACAGACCCATAATATGTTCCAACTGTTCCGATGAACTAACGTCCGCGTACGGTTTCAAGAACAATTGTTTGAAGATTGAAGAACGGATAAAAAAGTATATGGTGAACGCTGAAGGCAAACTACTATTAGAGCAATTTTTGGAACTGGAAAATCATAATGAAAGCATGCAGCAAGTAAAGGAAGAAATTTTAGACGAGTTTGATTACGAGATTCCGCTTGAAGATGTTTCTATCGAGGTTAACATTGATGATAAAAGAGAGATAAAAGTTGAAGAGAAAGTAATATGTAAATTCTGTAATAAAACTTTTAACACCACAGGAAGGCGATGGTCTGACCACATAAGAACACATTTAAAATCAAGTTTTGTTTGTGTGATTTGTTACGAAGGTTTTAAATCGAGGTTGGAATATTTAAAACACAGGAAGGAAATCCACGAACAAGGTGAAACGAGATGCCCTATATGCAATAAACACATTTCATACAAAGCCAACCTGGCAAGACACATAGAAAGCCatgaaaagaacaaaaaaaaacattacgaATGTAATTTCTGCGGCTTAAAACTAAAACACCGAGAAAAACTAACCGAACATCTTCGTATTCACACTGGCGAACGTCCATTTAAATGTACCTTTTGCGGGAAAACATTTACGCAATCTAGTACGCTATCCACTCACGTAAGAAGTGTACATATGACCGAGCGTCCCTACGTTTGTGAAATTTGCGGTCGGACATTTCCTGTAAGAGGGGCTTATACTGGTCATATGAATCGGCATAAAAATCTCGAGAAGAATTACGTTTGTAGTTTTTGCGGAAAGGCTTATCGTATCGAGAGTCAGTTAAAAGACCATGTTAAACGGCATACTGGGGTTAAAGATTACATCTGCGAGGTTTGTAGTAAAGGTTTTGTCAATAATACTGGGTTAACAAAGCATATGAGGATACATAATGGAGATAAACCGTTTCAATGTCATATTTGCCATAAGAGGTTCACGCAGAGTTACAATATGAAGATACACGTCAGGTCTTGTATCCAAAGGAACTCCGGTGCAAATATTGTAGCTACGGTTGATGGTGAATGA
Protein Sequence
MPLICRLCLKTNLENYNSVDVDDTRLKILSIIPEIDIDIVDRPVICSDCSEVLTTAYSFKQNCLKIEERINMYTGNVVSKIILENFLELYNHTENKEVKEEKPKEILYEVDCEALLEDVSPENNTVDVETIKIEENPRETIVEKTVCKFCNKKITRTGKQWVYHIGKHIKTKYICFICCEGFNSKWEYVSHKTEKHGRIPGTTRCHICNKEFSSTANMKKHLPMHKKKKAPAFQCDVCGLKVKQYAILQTHLRTHNGERPFKCKFCEKAFAQSSTLSTHVKAVHMTERPYICEFCGKTFATNSDCSSHVKVHKDIEKNYVCSICGKAYDVANKLDLHMKRHNGVKDYVCEICSKGFVNRHGLNRHVRRHNEDKQFECHDIDVVDRPIICSNCSDELTSAYGFKNNCLKIEERIKKYMVNAEGKLLLEQFLELENHNESMQQVKEEILDEFDYEIPLEDVSIEVNIDDKREIKVEEKVICKFCNKTFNTTGRRWSDHIRTHLKSSFVCVICYEGFKSRLEYLKHRKEIHEQGETRCPICNKHISYKANLARHIESHEKNKKKHYECNFCGLKLKHREKLTEHLRIHTGERPFKCTFCGKTFTQSSTLSTHVRSVHMTERPYVCEICGRTFPVRGAYTGHMNRHKNLEKNYVCSFCGKAYRIESQLKDHVKRHTGVKDYICEVCSKGFVNNTGLTKHMRIHNGDKPFQCHICHKRFTQSYNMKIHVRSCIQRNSGANIVATVDGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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