Mpro006585.1
Basic Information
- Insect
- Melinopterus prodromus
- Gene Symbol
- Zfy1
- Assembly
- GCA_964023965.1
- Location
- OZ030390.1:39424012-39440172[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.44 44 6.5 1.5 1 23 155 178 155 178 0.93 2 21 0.045 4.5 9.6 3.5 1 23 183 206 183 206 0.90 3 21 0.0025 0.25 13.5 2.2 1 23 214 236 214 236 0.98 4 21 0.0016 0.16 14.1 0.3 1 23 242 264 242 264 0.98 5 21 0.0016 0.16 14.1 0.3 1 23 270 293 270 293 0.95 6 21 3.1e-05 0.0031 19.5 1.2 2 23 305 326 305 326 0.97 7 21 3.8e-05 0.0038 19.2 1.8 3 23 334 354 333 354 0.98 8 21 0.0001 0.01 17.9 2.5 1 23 360 382 360 382 0.97 9 21 1.5e-05 0.0015 20.5 0.7 1 23 388 410 388 410 0.97 10 21 0.0027 0.28 13.4 0.0 1 21 416 436 416 437 0.95 11 21 4.2 4.2e+02 3.4 0.2 2 23 455 477 454 477 0.87 12 21 0.46 46 6.4 0.0 1 23 496 518 496 518 0.96 13 21 0.0051 0.51 12.5 1.9 1 23 522 544 522 544 0.98 14 21 0.057 5.7 9.2 1.4 1 23 549 572 549 572 0.97 15 21 0.31 31 6.9 0.3 1 12 578 589 578 593 0.90 16 21 0.012 1.2 11.4 1.1 1 23 606 629 606 629 0.94 17 21 3.3e-05 0.0033 19.4 0.9 2 23 641 662 640 662 0.97 18 21 9.1e-06 0.00091 21.2 1.6 3 23 674 694 672 694 0.96 19 21 9e-06 0.0009 21.2 1.4 1 23 700 722 700 722 0.98 20 21 1e-05 0.001 21.0 1.1 1 23 728 750 728 750 0.99 21 21 0.001 0.1 14.8 0.2 1 21 756 776 756 777 0.95
Sequence Information
- Coding Sequence
- ATGGGGAACTCAAAACTTACCCAGTTGCGGCACGACGGTTTCTGGAAAATAATTTCAACTGTGTCTTTGGAGCCTGAAGTTGTGCTTTCCGAACTCCATACCAGTTTAAAATGGAACAAAAAGCTGCCAGAGATTGACATAATTCCCGTAGACAACGATGGAGCTCTTATAGAGAACGATTATTCGTCATCGGAAGAGGAGTTCATTAAAATTCCAAAGAAAAATCAACATCGATCGAATGCTACTGGTGGATATGTGAACCCTTTTGTCTACAACAAGAATAGCAAAAGGGGTGGTAAAAGGAAATCCAAGAATGCTGATCTTTTTAGTGCAAAATGGGGATGCATTCTTTGCAGCGTGATTGCGAAGGATAAAGATAGTTTAATTGAACATTATGAAATACATAAAACGAAGAAGCATGCGGAATCCACCGTTGATCCAATTAAAAAGGAATCCGAATATTTTAACTGCGCTGTCTGTTTTCAAGAATTTACATCTATGAAAGCTTACGAAAAGCATTTTGATAGGAAGCATGGCGAGCGAAAGTACACCTGttttatttgtgaaaaattTTACAAGGATGCTTTTCAATTATGTCTCCATAATTTTTCGGCCCATCCTACTGGCTCGGGCGATTCTTATCACTGCAACATATGTGACTACCAAACAGAAGCCAGAAAGAATCTCAAGGACCATATGCAAAGTCATGAAGACTCTTGCTTGTTTAAATGTGACCTTTGTAATCGGGGATTTGACAACGATGGTAGCTTGGAGGAACACAAATCAATGCACGGGAGCGCTTCGTCCTTCTCATGCGATGTATGCGGAGAGACATTTCCTTATACAAGATATCTTGACGCTCATAGAAAGGCTAACCATCCTGAAATATTCGGTGATAGTCTATCAACAAACGAATGTCATTTATGCAGCAAGAGCTTCGCTGATaagaaaagtttaattttacatATCCGTGGTCATACGGGAGAGAATTCTATATTGTGTGATATGTGCGGCAAAAGACTGTCCAGCAGTGAGCATCTCAAGCAGCATTTAAGGGTTCACACGGGCTACAAGCCTCACATTTGTTCTGTCTGCGGAAAGGGATTTGCAAAAAAGTGCAATTTAACCCTTCATGAGAGAGTACACAGCGGGGAAAAGCCCTATATATGTAAAGTTTGTACAAAGGCTTTTTCACAACGGTCCACATTGGTTATCCATGAGAGATATCATTCCGGAGACAGACCATATGTTTGCACCCTTTGCAACAAAGGTTTCGTTGCCAAAGGATTGCTAAGTGTTCATATTAAAAGTTGTACTGTTATTCCCGCTGAGGACGATGATAAGTCACTGTTAGGAAAATGGGAGTGCAGAAAATGTCTATTATGGTACACATCGCGGGCAGCGTTAAGGAAGCATCGTGCTGAAATGCATACATCTCCAAAAGATCATTTGTACGACTTTGTTTACAATGCTACTGAAGACGTGTATGTGTGTAAAACGTGCGACTACGATACACCGGATGTGGTCGATATTGAGGATCATGTCAAAAGTCACGAAGCGACCTACGTTTGTATgcattgcaaagaaaaattctCTCAACCGTACAAGTATGGGATTCACGTCCAATCACACGAAGGCGGAGAATTTAAATGCCCAATGTGCGATTATAAGAACCACAATCGGAATAGTCTTTTGCAGCACATTAACATTGTACACTTGCACAAATTCTTGCATCATTGTCAGTACTGCGGGAAGGGCTTCAATGATATTATAGCTCATGGCGAGCATGAAAATTCCCATGAAGGCGCGAAGCCATTTGTTTGTATAGTGTGCCAGAAGGAATTCGTTTACTCGAGGTATTTACTTACACATCAAAAGAGGAACCACAGGGTTACTATCGAGGGCGTTCCGATTCCAAATCAGTGCCCAAAGTGTGGTAAGCTCTTCTCAAGAGCTTCCAGCGTTCAgaaccatttgaaatttcacgACAAGGATTATAAAACTCCGAAGAGTCACCTGTGTGATATATGCGGAAAAGATTTTAGGCAAAAGGAAAAGTTAACTATTCATTATCGAGTTCATACGGGGTATAAACCATATAGTTGTAGTTACTGTGAGAAAAGCTTTACAAAAAGGGATTATTTAATCATGCACGAGCGTGTGCATAGTGGGGTAAAGCCATATTCCTGCGAATACTGCGGCAAATGTTTTAATCAAGGCGCTCCCTTAAAGATACATGTTAGAACCCATACAGGGGAACGTCCTTATGTCTGCCATATCTGTAGTAGTGGGTTTACATCTAGAGGTGCGCTAAACCAACACCTTAAAATTTGTAAGGGCACCACTAAATTCCTTGGACAGTAA
- Protein Sequence
- MGNSKLTQLRHDGFWKIISTVSLEPEVVLSELHTSLKWNKKLPEIDIIPVDNDGALIENDYSSSEEEFIKIPKKNQHRSNATGGYVNPFVYNKNSKRGGKRKSKNADLFSAKWGCILCSVIAKDKDSLIEHYEIHKTKKHAESTVDPIKKESEYFNCAVCFQEFTSMKAYEKHFDRKHGERKYTCFICEKFYKDAFQLCLHNFSAHPTGSGDSYHCNICDYQTEARKNLKDHMQSHEDSCLFKCDLCNRGFDNDGSLEEHKSMHGSASSFSCDVCGETFPYTRYLDAHRKANHPEIFGDSLSTNECHLCSKSFADKKSLILHIRGHTGENSILCDMCGKRLSSSEHLKQHLRVHTGYKPHICSVCGKGFAKKCNLTLHERVHSGEKPYICKVCTKAFSQRSTLVIHERYHSGDRPYVCTLCNKGFVAKGLLSVHIKSCTVIPAEDDDKSLLGKWECRKCLLWYTSRAALRKHRAEMHTSPKDHLYDFVYNATEDVYVCKTCDYDTPDVVDIEDHVKSHEATYVCMHCKEKFSQPYKYGIHVQSHEGGEFKCPMCDYKNHNRNSLLQHINIVHLHKFLHHCQYCGKGFNDIIAHGEHENSHEGAKPFVCIVCQKEFVYSRYLLTHQKRNHRVTIEGVPIPNQCPKCGKLFSRASSVQNHLKFHDKDYKTPKSHLCDICGKDFRQKEKLTIHYRVHTGYKPYSCSYCEKSFTKRDYLIMHERVHSGVKPYSCEYCGKCFNQGAPLKIHVRTHTGERPYVCHICSSGFTSRGALNQHLKICKGTTKFLGQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -