Most025397.1
Basic Information
- Insect
- Melikaiella ostensackeni
- Gene Symbol
- -
- Assembly
- GCA_032362435.1
- Location
- JAUMHM010000078.1:40610597-40614178[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 1.4 4.7e+02 3.8 1.5 1 20 105 124 105 128 0.93 2 12 0.013 4.1 10.3 4.6 2 23 269 291 269 291 0.91 3 12 0.00036 0.12 15.1 1.8 2 23 377 399 376 399 0.95 4 12 0.024 8 9.4 0.9 1 23 557 580 557 580 0.96 5 12 7.3e-05 0.024 17.3 0.5 3 23 630 650 628 650 0.96 6 12 0.0017 0.56 13.0 0.3 2 23 672 694 671 694 0.93 7 12 0.0092 3 10.7 3.6 2 23 735 757 734 757 0.96 8 12 0.12 40 7.1 4.2 3 23 772 793 770 793 0.92 9 12 0.00018 0.058 16.1 0.1 2 23 838 860 838 860 0.93 10 12 0.048 16 8.4 1.5 1 23 938 960 938 960 0.98 11 12 0.00012 0.039 16.6 4.2 2 23 975 997 974 997 0.96 12 12 0.0012 0.38 13.5 1.3 1 23 1068 1091 1068 1091 0.98
Sequence Information
- Coding Sequence
- ATGACGTCTACAGTGGCCCAGGAATTTCGGCTACCCGAACCAGCTGACCCCGAACCAGTGGACAGCGACGGGTCCAGCAATGAGGACCGAGATGCCAGGAAACGTCTCCTTGGAGAAATGGATTCGTCAGGAcctaaaaaaagacgaaaacaAGCAACTCCTGTGAGGTTCCCAACTTCCCTCATGCTCGGCGATCATCCTGAGTCtgaggaagaagaggaagatGCAGACCCGGAAGGTAAGCCGAATTCGCCACGAGCGGAGACGCTTCAAGGCCACCCACCAACGAAAgacgaaaatttaaacataGAATTCCGCTGCCAGTACTGTAGTCAATTGTTTGATGGCAAAGCAACCCTCGACCTGCACCTCGAGTGTGAGCACAATTTTGTAATCGCGTCCCACCTACCTTCAGGTAGCCAGTCTCCTCAGCCGGAAAGTCAAAATCAAACGTCTGTAGAAACGATCAATCAGCAATCTGATCAATCTCTTCAGTTACCTCACCTCCCcaatatcgaaataaaaaatttaggctCTTCATGGCTCTCTGAGCATGTGCAATCTCGGAATCACAATCAAAATCAGATGCAGACTCAAACCCAACAACAGAGTGAAGAATGGTCAGCGAACTGTCGTATGAGTCCCATCACTTCCATGCCAAATCATCTAGCAGGATTGCCAAATTTTCCTGGAGGACTTCAACAGTATTTCCCTCTGCCCCCAGGATTTACCCTTTCCGATTCTGGCCAGATTCATCGAACCACTTTGGGGCCAGCACCGGTGCGGATTTTTAATCCCGACGCTTACTGTGATCTCTGCAATAAGGAATTTTGCAACAAGTATTTTCTCAAAACGCACAAGGCTAACAAGCATGGGATTTACGTGGATCCTCCGAATCCAATGACAGCGGGAGAGAGTAGTGTAGGAGTTGGACAACTTTGTCCGATAGGACAAATGACTGGGAGTAATATTAAGTTGGAACCTAATCAAAAATTAGAAGGTGGTATTCTTGTTCAAATGCCACAATTACAACACATACCACAATTAGCACAGTTACCACAATTACAACAGTTGCCACAATTGTCGCAATCACCTCAGGTGACACAACAACCACCACCTCCTACCGTTCCCTGTGATATTTGCCATAAGAGGTTCCGAAGCGAGGAATCTGTTAGGAAGCACAAGCAAAAGGTGCACACTCCATCAGTTTTTCAAAAGGATGATCAGAAAAATCTTAATCATCAGCTCCCACAACCCGATGAGGATAGAGAGCTGCACCACCAAAGTCCTGGGGCAATGGAGATGCTCTTCAAACAAGAATATGGAGTTGAGCAGGAAGACAATTCATTCATGCCCCCACCAAGACATCTTTCCCCTCAAGCAATTCAACAAGCCAAAGAATCTAACTTCAGTGCCGAACGACTTCGCAGATTAGGAGTTTTGAACCCAGATGCGTTTTGCGAAATCTGTTGTAAGGAGTACTGCAACAAATTCACACTACGTACTCATAAGCTGAAGAAACATGGGATAGTTATCCAGGACAACGAAAAACCACCAATCAATCCGGGGTCAGCTGCTACTTGGCATCAAATACAAACCACTCCCTTGAACTTGATCATGAACGAGACAGGAAGTGGCTCTGAGTACAGCGATAGATCAACTGATGAGCATGAGTGCAAAGCTTGTGGAATTCGTTTCCAGAACCTTGGACTGTATGAATCTCATCGTCAAAAGGTTCATTCTGAAGAAAGTTCCCCTAAGATGGAGTTTGAGCCAGAATCTGTGGAACAACGAATTACAAACAACGATTCTATCTCAGAGGatcttcaaaaacttcaaaccATGATTTTACAACTCAATGGCCTCGAAACCAACAAGGTCTCTATATGTTCTATTTGTGGTAAGGAGTGTGACTCCAACGTGAGTTTGAAAGCTCATATGATGGAGCATGGTATCACGACAGAAGAGCCAGTCTCACCATctcatgaaaaatcatcaacCCCTATTACCACTTACTGTACCTTGTGTGAAAAAGAATACCAAAACCAAGAAGCTCTGAGGAAACACATCTCGGAGGATCATAAACAACCTTCTTACGATTCGACTTCTTTGTCACACGTGCCATCAATATCCATGCCCTCGACTCCAACGTCAGGTCAAGCATCTGAACGCAAAACTTCATCTTTAACTCCCACATCCAGTTACTGTGAAATTTGCAACAAAGAACTctgcaacaaatattttatgaaaacccATATGCAACGAATGCATGGtatcgaaattgaaaatggggCACAGATCGGTGGAGTTATCTGCAACATCTGCAACAAGGAACTATGCAGCAAGTATTTCCTACGTGTCCACAAACACAACACTCATGGAATTGTAGAAGAAGGCTCCAATCTTGGAAATAAACCAGAAAACTTTGATCCATCGAATTCAGATGATTCGGCTTTGAAACCTGAACAACTTGGTGATTTGAATCACAGATACTTCACCCATTTCACCGAGGTTTGCCCTATCTGTAACAGAAGATTTAGAAGCATCAAATGGCTCAAAGCTCACTTATTGGGTGACCATGGAAAAATGGGGATTGACAAATGGAGGGATTTGGAACAACAGTACCAAGCAAGCCAGAGGACCAACAGACTAGCAGGAACTTCGAGACCAAATCATCCAAATGCGCATCTGAAGATCCCCAACGGTTTCGAATCCTCCCAAAACAAAGTTCCCGATGTGAATGCAACCCTAGGGAGTCAAgtgctttcaaatttattcgGATCATCAATCGAAGATCAACAATCTAAGAGCTACAGGTGCTCCTACTGCAACTTCTCCACAACTGTCCTACCTTTTCTCTTCCTCCATGAAAGATCCCACATCAATCCTCAAGAATCTTCagcagaaaatgaaaaatttttgcaatgtcCTCTCTGTCCTCAAAGTTTCTCCCAACCAGAACACTTTCACCATCATCTTCTTACTCGTCACCAGTTTCCCAATCTACTTTCTCAGTTCCCAGCACCTATTTTCAACAACCTCAGGCTGGAAGCTTTTGTAGAGAAGAACAACGAAACAAAAGAGGTGGAAATTGAACGAGAGGAACAGAAAAACCCGAGTCCCCAATCTCAGAATGATTTTAATGAACCcagtattcagaaaaagaatgaCACAGCAGTTCAGGTGACACCTGAAGGGGTCTATAAATGTTCACAGTGTGGATATGCGACAACAAATTTAAATCGCATCAAAAAGCACATTAGAAAAGATCACAAGGCGTTTGGAGAACCGACGGAAAGTGTTATTGCTGAGTTAAGCAAAATTCTTAAGGAAGTTGCCAATAAGCATAAAGTTCCTGCGAGTTATGCGATGCCTCAGGACTTGAATTCGAATCCGGAGAAAACGATAATGCaaccttttttgattgaagagcAGCAGTTCTCCCCAAGTCAGGATTGTGGCACAACTGGTGGGGAAGAAGCTGTACCTTTGAAGCGTTTTGCACCGGCCTTGGTCTACCTGCCAGTTAAGGCAAGAGTCAATGGCTCCCTCACAGCATCTTTCACCTTGAATCCTGCATAA
- Protein Sequence
- MTSTVAQEFRLPEPADPEPVDSDGSSNEDRDARKRLLGEMDSSGPKKRRKQATPVRFPTSLMLGDHPESEEEEEDADPEGKPNSPRAETLQGHPPTKDENLNIEFRCQYCSQLFDGKATLDLHLECEHNFVIASHLPSGSQSPQPESQNQTSVETINQQSDQSLQLPHLPNIEIKNLGSSWLSEHVQSRNHNQNQMQTQTQQQSEEWSANCRMSPITSMPNHLAGLPNFPGGLQQYFPLPPGFTLSDSGQIHRTTLGPAPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYVDPPNPMTAGESSVGVGQLCPIGQMTGSNIKLEPNQKLEGGILVQMPQLQHIPQLAQLPQLQQLPQLSQSPQVTQQPPPPTVPCDICHKRFRSEESVRKHKQKVHTPSVFQKDDQKNLNHQLPQPDEDRELHHQSPGAMEMLFKQEYGVEQEDNSFMPPPRHLSPQAIQQAKESNFSAERLRRLGVLNPDAFCEICCKEYCNKFTLRTHKLKKHGIVIQDNEKPPINPGSAATWHQIQTTPLNLIMNETGSGSEYSDRSTDEHECKACGIRFQNLGLYESHRQKVHSEESSPKMEFEPESVEQRITNNDSISEDLQKLQTMILQLNGLETNKVSICSICGKECDSNVSLKAHMMEHGITTEEPVSPSHEKSSTPITTYCTLCEKEYQNQEALRKHISEDHKQPSYDSTSLSHVPSISMPSTPTSGQASERKTSSLTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVEEGSNLGNKPENFDPSNSDDSALKPEQLGDLNHRYFTHFTEVCPICNRRFRSIKWLKAHLLGDHGKMGIDKWRDLEQQYQASQRTNRLAGTSRPNHPNAHLKIPNGFESSQNKVPDVNATLGSQVLSNLFGSSIEDQQSKSYRCSYCNFSTTVLPFLFLHERSHINPQESSAENEKFLQCPLCPQSFSQPEHFHHHLLTRHQFPNLLSQFPAPIFNNLRLEAFVEKNNETKEVEIEREEQKNPSPQSQNDFNEPSIQKKNDTAVQVTPEGVYKCSQCGYATTNLNRIKKHIRKDHKAFGEPTESVIAELSKILKEVANKHKVPASYAMPQDLNSNPEKTIMQPFLIEEQQFSPSQDCGTTGGEEAVPLKRFAPALVYLPVKARVNGSLTASFTLNPA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00011446;
- 90% Identity
- -
- 80% Identity
- -