Basic Information

Gene Symbol
ZIPIC
Assembly
GCA_032362435.1
Location
JAUMHM010000031.1:15046746-15072454[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.39 1.3e+02 5.6 0.1 1 23 55 77 55 77 0.95
2 13 0.0016 0.52 13.1 0.2 1 23 91 113 91 113 0.97
3 13 1.9e-05 0.0061 19.2 1.8 1 23 119 142 119 142 0.98
4 13 0.28 91 6.0 0.6 1 19 305 323 305 326 0.94
5 13 0.0016 0.53 13.0 0.3 1 23 439 461 439 461 0.98
6 13 7e-06 0.0023 20.5 0.9 1 23 470 492 470 492 0.98
7 13 0.00027 0.089 15.5 1.4 1 23 498 521 498 521 0.97
8 13 9.4e-05 0.031 16.9 4.7 1 23 1032 1055 1032 1055 0.97
9 13 0.035 12 8.8 3.9 1 23 1147 1171 1147 1171 0.96
10 13 1.3 4.3e+02 3.9 1.8 1 23 1234 1259 1234 1259 0.96
11 13 2.8 9.2e+02 2.9 0.3 12 23 1314 1325 1304 1325 0.80
12 13 0.001 0.33 13.7 4.7 1 23 1331 1353 1331 1353 0.98
13 13 1.4e-05 0.0047 19.5 0.5 1 23 1502 1524 1502 1524 0.98

Sequence Information

Coding Sequence
ATGAGTCGGATCGTTGTAAGAGAAGAGAGGCAAGGGAGAAAGGAGAAGTACTACAGGGCAGGCGTGATTGTGAATCCAAAGATCGGACTATATCAGACACACAGCAGTGAGACTCAAACTGACATTGCATCATCGTTATTGattgaccAATCAGAAGAATCGCATCCCTGTCCAGCGTGCCCCTCAATTCTCCCAACAGTACGGGACTTAACGAACCACCTGCGAAACCACAATTCGCCACGAAGTATCGACTGCAGCATCGACGAAGAATTTAGCTGCAGAGTATGTTACAAAGTACTAAGTTCGGCCAGTTCCCTAGACCGTCACGTTCTCGTGCATTCCGGTGAGCGGCCCTTCAAATGTAAACAGTGCAACATGGCTTTCACCACTAACGGAAACATGACGAGACACTCAAAAACAGCTCACAATCATCTGTCACCAAACAGCTGCTCTGATTCTGAAGCCAGCAATGATTCAGAATCGCCCTCCAAAAAATTCGAGGAGTACAACAACAATGAAATCGCCAAACGAAACTCGCCTGACCTCATTGACAAACTACAGTCTTCCACTTTCATCAAAAAGAGGAAATCCCTCGACTACACGGAAGATCTTAGCTTGCAGAAGAAATTCAAAACCAACTTAGACAGTCAGAACTACAATTGTCATCCCGACTTCGACAAATGCGAACCCGACAATTTGTCCACCAAAAACCACAGAGTTTTGAATCTTCATCGATCAGAGAAcaactttgatgaaaattcccTTAGGAATGTCGCGAGGACCTTGAGACATTCGGTTGAAGGATTTAGAGACCTAACATTCGTCGACTTTACATCCACAAAGTACCCTGTCATCGCCAGGGCAAAATGTGAAGAGTTCCTCCATCGACCAACATCCGGGGACATGGCGAAGTTCCAGTGTTCGAAATGCCTCCGGGCTTTTCCTTGCAAATCAGCTTTGGAGTCTCATGAACTGGAATGTGGACTTCCGAATATGCAATGGAAGGGTAGTGATGTTCAATCCAGAAGGGATGATTTTTTTGCAGGACTTAATCTACAAAACAAGGCAGCCATGACAGACGCTAAAGAGGGAAAAGACCTTGCTGATATCCAGAGCATCATCAGCCTTACCTCGAGTCCGATACTCCACAACTTCTCTAGATCCGATGCAAGCACTCCTGACAACTGCAGTAATAAAATAAACCAGAATGTTGGATCTTCTGGATCATCAGGAACCCTTTCTTCAGAGTATCATGAGGAGGAGACTCAAGATGCTTTTGCAGCCGAgttcagaaaaatgaaactcAAGGGCGAGTTTCCTTGCAAACTTTGCAAGGAAATCTTTCCCAACTTGAGGGCCTTGAAAGGACACAATAGAACCCATTTAGGTGTTGGACCTGGAATGCCCTATCCATGTAACATCTGTCCTTATACAAGCACTGACAAGACAACCCTCACGAGACATCTGAAGACACACAATGGTGATAGACCTTTCGAGTGTGCCGAGTGCGGCTACGCTTTCACGACGAAAGCCAACTGCGAAAGGCACGTGAGGAATCGACATGGGATTCATGACAAAAATGATGTTCAGAAGATGATCATCTATCATCCGACTGAAGACTCTACGAATGAAAGTTTGGATCGGACATCATCAAGAAGTGTCAAAGATGAAGTAAGGAAGGCTCTCGTTTATCCCAAAGAGGAACCACTTCCCCCGAATCATTACTCTGTAATGATGCAACCAGACATTAGGATAAAAGAAGAAAGTAAGGTCATCAAGGAGATGAGTCCCATAAGTCAGCTAAACCAAATTAATCAGCTCAACCAACTTAAGCAGCTGAACCAAATAAGCCAAATCAATCAACTGAATCAAATAAACCAAATTAACCAGATCAACCTTCAGATTAACCACTACGATAAATCGGAGGTGTTCCCCAGGCCAAAATCAGTTCAACCTCTCGAGTTGACTTACAGAACTTCCCCCCAACATCTAATCATGAAGTCTGAAAATTCGAGAATAGATGAAGATCTCGAGTCGAGGTCATCGGAGGACAGCGTATCTCTAGTCAATGAAACCAAACCGGACGTTCACCAAAGAATACAAGCTAGTCCGATGAACTTGAAGAAAGTCGCGAATGATTCCTCCAACGTGGCTTCGAGCGACGATGTACCCCTGGATCTCTCGATGGATGTTCTTGACCTGAGCAAAAAATCCAAGCAAAAACcagaaataaacgaaaattccGATGAACATAATGAAAACCAAAAGGACTTTTACAATGCTACAAATCCTCTCTTGCTGACACGAGCTTTATTAAAATCTCATCAAGTTTCCCCTCCAACTTCCTTGGAAGCTTTAATAGATGAAGATCTCGAGTCGAGGTCATTGGAGGACAGCGTATCGCTAATCAGTGAAACCAAACCGGACGTACACCAAAGAAAACAAGCTAGTCCGATGAACTTGAAGCAAGTCGCGAATGATTCAAGTGACGATGTGCCCCTGGATCTCTCGATAAATGTTCTTGACCTGAGCAAAATATCCAAGCAACctgaaataaacgaaaattccGATGAACATAATGAAAACCAAAAGGAATTTTACAACACCACGAATCCTCTCTTGCTGACACGAGCTTCATTAGAATCTCGTCAAGTTTCCCCTCCAACTTCCTTGGAAGCTTTGTACGCCAATGCACATGCGAACATGATCTACAGCAATTTGGCTCTAGGATTAGCCGGTGCAGGTTTGATAgcacctaattttttcaatcgactTTCTGATCAGGGCTACGTGATGAAAGAAAGATTACAGAAGAAACTAGTTAGAGGTCTTCAAACCAGTGGTGGTATTTTGGTCGAGGAGTCACTTGAAAATACAGGATTTAATACCAGCTATCCTCCAGGAAGAAACTCCCAACAACTAGATGAACAGGTGAACTATTCAAACCTGGTGCAGCCGAAATTTCCCAGCAAGGTTATCTCACCCAGAGAGAGAATCAGCGAATCTCCCTCGttaaattctatcaaaatggTCATCAAGAATGGTGCCCTCATGACCAAACAGAAGCAGAGGAGGTACAGGACTGAGAGACCTTTTACCTGTAAATATTGCTCAAAAAAGTTCACACTCAAGACTAATGTGACGAGACACATGAAACAACAGCACAATGCCTTGTGGCATCAAAGACCTAGAGGTGGTCATTCGACCGGAGATCGACCTCCAGCGAGACCTCAAGCGAGACCTCCAGGGTTGCATCAAGATGTAGACCAGACTTCTCAGACCTTCCTGAACAGGAGCTTTCCCTATGAAGTTCCATTGCAGAAAGAGGGTCAGCGAGCAAATACTAGAAGCACCAGGAATTCTTCCTCTCCTGATGGCCAAGACATGAGGGTGACGAATAACAATTCTTTCTCGACGAGAAACGTTCCAGAGAGATCCTACAAGTGTAATCAATGTCCTTGTTCCACTTTCGCGACCTTAGAGAATCTGAAGAAACATCGATCGACTAAACACTCTAGACAGACGAATTTTAGGTCTGAGACTTCTTCCAGTGATCCTCAGAATTCTGACAACTGTCAGAAACAGAACGATCAAAGTTCTTCCTCTTACTTCCTTCCTCTTACTTCCCCTTCGACGAATGAGAATCTTAAGTCGTGTAAGGCTTCACCAAGGTCTTCACCTGAACCAGCAGACACGCCCTTCAAGTGTCATGTTCCGAATTGTGATAATGGATTCGCTGATCGTCAGGACTGCTTGGATCACATCAAGATGAATCATAAGCGAGACTATGAGATCCTGGTTTCCAAGGGTTATTTGCAGATCGGGATTCATGCTATTGAGGAACAACCTCCACCGACTCAGCACTCGAGCGATGGGCCCAGGTTCCTTGACTACAAATATAGAAAgGTGGTCTGTGCATTCTGCATGCGACGACTTTGGTCAGCCGAAGATCTTCGACGTCACGCCAGAACCCACACAGGAGAACAGCCCTTTTCTTGTGACATCTGCGACCGGAGATTCAGCATAAGACACAATATGTTCCGTCACCGGAAGCAGCACGAAGCGGCGGACTCAACAGTCTACCCTGGAGGTGGTGACGAGGAAATTTCTCCGACCCACCCTCCTAAAATCACTCCCCGAAGACTTAATCTACAAAACAATGTAACCATGGCGGACGCTAAAGAGGGAAAAGACCTTGCTGATATCCAGAGCGTCATCAGCTTTACCTCGAGTCCGATACTCCACAACTTCTCTAGATCCGATGCGTGCACCCCTGACAACTGCAGTAATAAAATAAACCAGAATGTTAGATCTTCTGGATCATCAGGAACCCTTTCTCCAGAGTATCATGAGGAGGAGACTCAAGATGCTTTTGAAGCCGAGTTCAGAAAAATTAAGCTCAAGGGCGAGTTTCCTTGCAAACTTCGCAAGGAAATCTTCGTCAACTTGAGGGCCTTGAAAGGACATAATAGAACCTATTTAGGTATTGGACCTGGAATGCCCTATCCATGTAACATCTGTCCTTATACAAGCGCTGACAAGACAACTCTCACGAGGCATCTGAAGACACACAATGGCGATAGACCTTTCGAGTGTGCCGAGTGA
Protein Sequence
MSRIVVREERQGRKEKYYRAGVIVNPKIGLYQTHSSETQTDIASSLLIDQSEESHPCPACPSILPTVRDLTNHLRNHNSPRSIDCSIDEEFSCRVCYKVLSSASSLDRHVLVHSGERPFKCKQCNMAFTTNGNMTRHSKTAHNHLSPNSCSDSEASNDSESPSKKFEEYNNNEIAKRNSPDLIDKLQSSTFIKKRKSLDYTEDLSLQKKFKTNLDSQNYNCHPDFDKCEPDNLSTKNHRVLNLHRSENNFDENSLRNVARTLRHSVEGFRDLTFVDFTSTKYPVIARAKCEEFLHRPTSGDMAKFQCSKCLRAFPCKSALESHELECGLPNMQWKGSDVQSRRDDFFAGLNLQNKAAMTDAKEGKDLADIQSIISLTSSPILHNFSRSDASTPDNCSNKINQNVGSSGSSGTLSSEYHEEETQDAFAAEFRKMKLKGEFPCKLCKEIFPNLRALKGHNRTHLGVGPGMPYPCNICPYTSTDKTTLTRHLKTHNGDRPFECAECGYAFTTKANCERHVRNRHGIHDKNDVQKMIIYHPTEDSTNESLDRTSSRSVKDEVRKALVYPKEEPLPPNHYSVMMQPDIRIKEESKVIKEMSPISQLNQINQLNQLKQLNQISQINQLNQINQINQINLQINHYDKSEVFPRPKSVQPLELTYRTSPQHLIMKSENSRIDEDLESRSSEDSVSLVNETKPDVHQRIQASPMNLKKVANDSSNVASSDDVPLDLSMDVLDLSKKSKQKPEINENSDEHNENQKDFYNATNPLLLTRALLKSHQVSPPTSLEALIDEDLESRSLEDSVSLISETKPDVHQRKQASPMNLKQVANDSSDDVPLDLSINVLDLSKISKQPEINENSDEHNENQKEFYNTTNPLLLTRASLESRQVSPPTSLEALYANAHANMIYSNLALGLAGAGLIAPNFFNRLSDQGYVMKERLQKKLVRGLQTSGGILVEESLENTGFNTSYPPGRNSQQLDEQVNYSNLVQPKFPSKVISPRERISESPSLNSIKMVIKNGALMTKQKQRRYRTERPFTCKYCSKKFTLKTNVTRHMKQQHNALWHQRPRGGHSTGDRPPARPQARPPGLHQDVDQTSQTFLNRSFPYEVPLQKEGQRANTRSTRNSSSPDGQDMRVTNNNSFSTRNVPERSYKCNQCPCSTFATLENLKKHRSTKHSRQTNFRSETSSSDPQNSDNCQKQNDQSSSSYFLPLTSPSTNENLKSCKASPRSSPEPADTPFKCHVPNCDNGFADRQDCLDHIKMNHKRDYEILVSKGYLQIGIHAIEEQPPPTQHSSDGPRFLDYKYRKVVCAFCMRRLWSAEDLRRHARTHTGEQPFSCDICDRRFSIRHNMFRHRKQHEAADSTVYPGGGDEEISPTHPPKITPRRLNLQNNVTMADAKEGKDLADIQSVISFTSSPILHNFSRSDACTPDNCSNKINQNVRSSGSSGTLSPEYHEEETQDAFEAEFRKIKLKGEFPCKLRKEIFVNLRALKGHNRTYLGIGPGMPYPCNICPYTSADKTTLTRHLKTHNGDRPFECAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-