Most029421.1
Basic Information
- Insect
- Melikaiella ostensackeni
- Gene Symbol
- -
- Assembly
- GCA_032362435.1
- Location
- JAUMHM010000083.1:39792845-39795846[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 2.4e-05 0.0078 18.8 2.8 1 23 344 366 344 366 0.97 2 12 0.0031 1 12.2 4.3 1 23 370 392 370 392 0.94 3 12 0.00033 0.11 15.2 4.1 1 23 397 419 397 419 0.96 4 12 0.00028 0.092 15.4 2.1 1 23 469 491 469 491 0.97 5 12 0.0039 1.3 11.9 1.6 1 23 496 518 496 518 0.97 6 12 0.00044 0.14 14.8 2.2 1 23 567 589 567 589 0.98 7 12 0.00024 0.078 15.7 0.8 2 23 597 618 596 618 0.97 8 12 1.3e-06 0.00041 22.8 2.1 1 23 629 651 629 651 0.96 9 12 0.00029 0.094 15.4 1.6 1 23 657 679 657 679 0.97 10 12 0.0002 0.066 15.9 0.7 1 23 685 707 685 707 0.98 11 12 6.1e-06 0.002 20.7 2.0 1 23 713 735 713 735 0.96 12 12 0.00011 0.035 16.8 0.3 1 22 741 762 741 762 0.96
Sequence Information
- Coding Sequence
- ATGGCGATGAACTCAACCTATTTTGGTATTCCACCGAACATGGACCGAATTTGCAGAGTATGTCTCACAGAAAGCACAAATATGTCCCCCATATTTTGCTCGGACCAAGAAGTTGATCATTTCTCAGGTCTCCcacagaaaattcaaatctgtGGCTCAATCGAGGTTCAGGAACAAGATGGCCTGCCTTCTTTAATTTGCAACGACTGCATCTTCAAAGCCAGTGTTGCCCACGATTTTAGGCAGCTTTGTCAGATTTCGGACGCTCGTTTGCGTCTTTATTATAATAAGCCTATCAGAAGTAATCTGATGGAATCCAGTACCCAGACTGATCCTCAAACTCGAattatatcaaagaaaaataccAACCAGCAAAATGGATACTGCGTGAAGGAGGAAGAACAGCatattttgtcagaaattcaTCAACCGACCGAAGCCTTTGTACGAGAAGAGAGCCCCATAGTAGAAGATTCCATAGAAATTCATGACGAAAAGCTGTATGAATGCAACCTCCAATTCGAAGTGCCCAAGGAGACTGAAAAAATGACTGAAGAATTAGCAAATGCAATTCATGCGAATGCAATGAATGCGAATGCAATGCATACAAGTCCAATTAATACAAATGCAATTAATACAAACGTTATTAACTCAAATATAATGAATGCTAACATAATTAATTCAAACACAATACATGCAAATCTAGTACCAGATAATACTCTGCAAATTCCATGTTCCGAGGAAATTTCAGTAGCGAGTGTTCGATTGAGTGATGTTCGATTGAGTGATGTTCGATTGAGTGAAGTGGATAAAACTGACAATGGAGATAAGACTGAAATTAATAACAGAACAGAAGACTATCTCGGCCAAGAATTGTTAAACGAGAGCTTAGAAGATCCTCAAACAACGTCCCCGAAAAGAACTTCAAGTCGCAAAGTTAAATCCTTGCAGAATAAAACTACATTCAGTGATGACGAAGTTGACAATTATTACGATCAAAGCAGCGATAGTCAAGATTCTGAGCCGCAATTTAAGTGTAAAATCTGTTCGAAACGGTACACAACCCAGAAAGGATTGAAGAAACATTCTCTGGTGCATAATAAGAAACATAATTGCAATGTCTGTTTAAAGACTTTCTGCAagcttgaaaatttggaaaagcacAAAGTGATTCATGTTGCGAAACCTCACGCTTGTCAGTTGTGTCACACCTCTTTTTCTAAACCACAAAGTCTGGTGAAGCATTTAAAGTCTCATACGGAAAAGGTGAATGATATTATAAAGCAAATTAGCAGTGATGATCAAAAAGACGTTAATGAGCCGAAGAAAGAATTGAAGAGCGATGAGGAAACTGAAGATGAAACGCCGAACGAGCCTGATGAGTTTGGAAACGCGCCTGAGTTGTTCAAGTGTGGAATATGCGGTCAGTTTTGTTCCACGATGAAAACTTTGAAGCGGCATGCTCTAATTCATGGAGAGAAGAAATATTCTTGCTTTGTGTGCAAAAAGTGGTTCTTCAGGCCTGACACGTTGAAAAAACATGCTGAGAAACATGGACATGGACTGCTGGACAATCTGATGGaggataataaattgtttgattcgGATGATGAACCTTTTCCGAGTTCTACggtaaatatttttggtgaTAATGATAAATCGAAGAAGGATGATAGTGATGAGGAAGGAACTGGAGAGTACAAATGTCAGCATTGCGAGAAAGTCATGGCTACGAAGAAGGGATTGAGAAGGCATGTGTCGATGCATAAACCGAAAGCTGAGCCCGTCACTTGTGAAATCTGCAAAAAGgtCTGTGCAAGTCAGGCGCGTTTGGTAATCCACCAGAAGACCCACAACAAGCCGAAGGAAAAAGTCCCAAGAGAATACCTCTGTCATATTTGCAGCAAAGTCTACCCAAGCAACTCTTCTCTAACTTATCACATGAGAACCCATACAGGAGTGAAGCCTCACGTTTGTAAAACCTGCAACAGTGGATTCACAACCACGACAAGCTTAGCTAACCACATAAGAATCCACACCGGAGATAAACCCTTTGTCTGCCATGTTTGTAGCGCAGCCTTCGCCGTCAGTTCAGCTTTCAGAAGACACCTAACTCGCCACACCGGAGAGGCCAATTACCTTTGTAAAACCTGTGGCAAAGCCTTCAAAAGACTCAGTACTCTTAAGGAACACACCTACACTCACTCAGGTGAAAAACCCTATGTTTGTAAAACCTGTGGCGCCGCTTACAGTCACAGTGGAAGTTTATTTGCCCATCAAAAACGTTGTCGAACCCAATACGGCGATCAAATGATGATGGACGATCATCATCATCATACTGTCGCCCATCATATTCACGTGAACAATGTGCAATCGGCAGTACGATCACTGGCTGTGATAGGtcagatattttaa
- Protein Sequence
- MAMNSTYFGIPPNMDRICRVCLTESTNMSPIFCSDQEVDHFSGLPQKIQICGSIEVQEQDGLPSLICNDCIFKASVAHDFRQLCQISDARLRLYYNKPIRSNLMESSTQTDPQTRIISKKNTNQQNGYCVKEEEQHILSEIHQPTEAFVREESPIVEDSIEIHDEKLYECNLQFEVPKETEKMTEELANAIHANAMNANAMHTSPINTNAINTNVINSNIMNANIINSNTIHANLVPDNTLQIPCSEEISVASVRLSDVRLSDVRLSEVDKTDNGDKTEINNRTEDYLGQELLNESLEDPQTTSPKRTSSRKVKSLQNKTTFSDDEVDNYYDQSSDSQDSEPQFKCKICSKRYTTQKGLKKHSLVHNKKHNCNVCLKTFCKLENLEKHKVIHVAKPHACQLCHTSFSKPQSLVKHLKSHTEKVNDIIKQISSDDQKDVNEPKKELKSDEETEDETPNEPDEFGNAPELFKCGICGQFCSTMKTLKRHALIHGEKKYSCFVCKKWFFRPDTLKKHAEKHGHGLLDNLMEDNKLFDSDDEPFPSSTVNIFGDNDKSKKDDSDEEGTGEYKCQHCEKVMATKKGLRRHVSMHKPKAEPVTCEICKKVCASQARLVIHQKTHNKPKEKVPREYLCHICSKVYPSNSSLTYHMRTHTGVKPHVCKTCNSGFTTTTSLANHIRIHTGDKPFVCHVCSAAFAVSSAFRRHLTRHTGEANYLCKTCGKAFKRLSTLKEHTYTHSGEKPYVCKTCGAAYSHSGSLFAHQKRCRTQYGDQMMMDDHHHHTVAHHIHVNNVQSAVRSLAVIGQIF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00676990;
- 90% Identity
- -
- 80% Identity
- -