Basic Information

Insect: Melieria crassipennis
Gene Symbol: zfh1
Assembly: GCA_963668005.1
Location: OY764961.1:130230928-130235554[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00012 0.011 16.7 0.7 1 23 202 224 202 224 0.95

2 15 0.0032 0.3 12.3 2.8 3 23 232 252 230 252 0.95

3 15 0.00063 0.06 14.4 0.1 1 23 391 413 391 413 0.97

4 15 0.00063 0.059 14.5 0.2 1 23 419 441 419 441 0.98

5 15 0.00016 0.015 16.3 2.1 1 23 473 495 473 495 0.96

6 15 0.01 0.94 10.7 0.3 1 23 511 533 511 533 0.94

7 15 0.0064 0.6 11.3 1.4 1 23 539 562 539 562 0.97

8 15 0.32 30 5.9 0.3 5 19 573 587 570 588 0.91

9 15 0.00019 0.018 16.1 5.6 1 23 597 619 597 619 0.97

10 15 0.081 7.6 7.8 0.4 3 23 626 646 624 646 0.96

11 15 1.1e-05 0.001 20.0 0.3 1 23 655 677 655 677 0.98

12 15 0.0056 0.53 11.5 0.2 3 23 685 705 683 705 0.97

13 15 6.7e-05 0.0063 17.5 0.5 1 23 711 733 711 734 0.95

14 15 0.028 2.6 9.3 0.1 1 23 744 766 744 766 0.97

15 15 0.016 1.5 10.0 0.0 1 20 1309 1328 1309 1331 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00012	0.011	16.7	0.7	1	23	202	224	202	224	0.95
2	15	0.0032	0.3	12.3	2.8	3	23	232	252	230	252	0.95
3	15	0.00063	0.06	14.4	0.1	1	23	391	413	391	413	0.97
4	15	0.00063	0.059	14.5	0.2	1	23	419	441	419	441	0.98
5	15	0.00016	0.015	16.3	2.1	1	23	473	495	473	495	0.96
6	15	0.01	0.94	10.7	0.3	1	23	511	533	511	533	0.94
7	15	0.0064	0.6	11.3	1.4	1	23	539	562	539	562	0.97
8	15	0.32	30	5.9	0.3	5	19	573	587	570	588	0.91
9	15	0.00019	0.018	16.1	5.6	1	23	597	619	597	619	0.97
10	15	0.081	7.6	7.8	0.4	3	23	626	646	624	646	0.96
11	15	1.1e-05	0.001	20.0	0.3	1	23	655	677	655	677	0.98
12	15	0.0056	0.53	11.5	0.2	3	23	685	705	683	705	0.97
13	15	6.7e-05	0.0063	17.5	0.5	1	23	711	733	711	734	0.95
14	15	0.028	2.6	9.3	0.1	1	23	744	766	744	766	0.97
15	15	0.016	1.5	10.0	0.0	1	20	1309	1328	1309	1331	0.93

Sequence Information

Coding Sequence: ATGGACAGACAATCGTATGGCATGCACTGGATACACCACACGGCGGAAAGTGTGAAAGACGCTGGTCAGTTGCTGGTGAAGATGCGCTCCTCACAGGCAGAGGGTGCGATTGCGGGCAATGGCAGTGTGGTTGACGGCGACGACGAGTACGGCGGCGTGCCCACAGAAGTAGATCTTGATCAAATAGCGGCCGAGAATCTGATTTTCATGGCACGCGATGGTCAAATGGTTGGCGAAATCTTAAACGCcggcaccgatgacaatggcactGTGGTGGTGAGAGCCGGCGACGGCACGCCCATCGACTGCGAGTGTGTGATGCAGCAGGTGGCGGCGGTGGCAGTAGCTGCTCCGGTGATATCGCCGGACGACATGGTGCAGTCGGCAGAAGATGCTGGTGGCGGTGGCTATGTGGACGAGTATGCGGACAACACGCCGCAGATGGTGACGGAGGAAGTGATAACTGATGACTGGGTGCAGCATCAAGGCGAGGAGCGTGTTGAAATACCCGCAGAGCAGATAATTGGTTCCAGTTCGCAAGTGTTGCTGGACATTGAGGTGCCGCTGCCCACCGTGCAAGACGAGTACACACTACTGCGTCCCTATCCCTGTGATTTCTGCAGCCGACGCTTCCGTAAAAAGGCGAGTCTGATGAATCACATGGTGGCGCACCAGAACGATCGACCGCATCTGTGCAAACTGTGCAGTATGCGGTTTTTTCGGCGTTCGGACTTGATAAATCACCTAAAAGCGCACGCCGATGCGCCAGAGCCTGAATACGAAACGGATCTCATGCACTTTGTGGAGCAAGAGCAGCACCAAATGCGTCATCCCAACGATCACTACTATGATCAAGATTGGAGTATGCAGGCCAATCCCGTAAAGATGATGAAAAATAATCGAAAGACGCAGAACGTTAGCGGCAATAGCTCGTCCACATCCACCTCGACGACAACAACACGAGGGCGCACCAGTCGCCTGAAGCCCAAAGAGGAGAACTACGGTCTTAGCGAATCAATGGTGGCACCCGGCGGTCGCAGTAATGGAATGGTTGCGACGGATATGGTTGAGTGCCAGCAATTGCAGGCATCGACGGCGGCGGTCAAGTTGACTCAGCATCATTCACCTGCGCATCACAAAACGTACCCTGTCGTCGATGACAGTAAACCGTTCGTGTGTCAGCAATGCGGCTTAGCGTTTGCACGAGAAAAGGCTCTGCTGTCGCATGCAAAGAATCATCGCACCGATTCGCCATATGAGTGCAATCAATGCAACGAAATGTTCTGGGATGCCGCCAGCCTGCAAGAACACCAGAAATCCCACCAATTTGAGGAGAGCAATTCGGAGTATGATCCAGGTGAGGCAGAGGCGGAAGAAACGCAAAGTGAGTCCGAATCTGAGCGGCTCTACGGCGAGTTCTACTGCAGCGAGTGCGGCATGTCGTTTCATCGCGAGGACTTGCTGCGCCGCCACTCCAAGGCCCATGACAATGCTGCCAACGACGGTGCTTCGGATCACAGTAAAGATCGCCACTGTTGCAATACCTGTGGCGAGACGTTTGCCGAGGCCTTGGATTTGCTAGCGCATGCGGAAATACATGCGCGCTACCCGCCCTTCAAATGTGTGCTGTGCGGCGAGACCTTCTTCGAGGAGCACACCATCAAGCGGCATTTGCAAAGCGCACACCCCAATGAAATGACGCCCAACTCATGCATTCTCTGCGGCAAGGAATGTCGCGATCGCAAGGCGCTTATCAAACACGCCTGGGACCATTCGCGAGAGAAGTGTCACTCGTGCTCAAAGTGCGGAAAGAACTTTCACAATAAGGCACGCCTGAAGCGGCACATGGCCTCGCACCGCGACAAGTCGGTCATCTGTGACGTGTGCCAGGAGGAGTTCCCAGATGGTCGCACGCTCTCGAACCATCGGCATTCGCACAGCGCCACCGCTTCGGGCAAGTTGTTTCCTTGCAACGAATGCGGCAAGACGTTCGGTTCGCGTAGCTCGCAACAGATACACGTGCGCATTCACACTGGCGAGCGGCCATATGGCTGCCGCTTTTGCTGGAAGGCCTTTGCTGATGGCGGCACGCTGCGCAAGCACGAGCGCATCCACACGGGCGAAAAGCCGTACGCTTGCTCGGTGTGTCCGCGCGCCTTCAACCAGCGCGTGGTGCTGCGCGAACACATACGCTCGCACCACTCGGGCGTGGACGCTAAGCGGGGCACGTTCTACTGCTCCGTCTGTTCGATAGATCTGTCGTCTTCAAACGACCTCATACAACATCTCATACAGCACAGCGATATGAATACTGCTATGCAGCGGAAACCCATTACTGGACCTCGGAAGTATAAACGTCGCCGCAAACTGAAGCCTCACGAAATTGCGCGTCTACGGAGAGAGAGTCAGCAGAACACCAACCCGAGCGAGAATGGCAGTGTTATTGACATGTCCGACTTCGACATGGATAATGTGGATGATCTACTGGGTATAGCTGAAACGTCGCCTATACCAAATAATGTGACAAAAGCAAGCAAGTCTAGGCGGCATAAAATTGCGGCGAAACATAAtggcaataacaatagcaatgGCGTTGGTAATGAAGCGCTGCTGGAAGATGTCGACGGGCATAAAAAGTTGCGCTACAATTCGAATAGTAGCAATTCGGACAAGCTGTGGCAAATGAAGCTCATCAACTCGAACACGAACGACGAGTCGTACAAGTCGCTGCTCTCGAATCTGGAAAATACGCTGCAGAGCATCGATACGTTGGTGGTGGGCAGCAATGGCGACATGAGCGGCCATGCGGACGAGGACAGAAAGCCAAAGTATAAATTGGAGAGTGCAGATGGGTGCGGTGGCAGCGCCCAGCGCACACAGGAAATACAATTAGCAAAGTTGGATAGAAAATATCAAGTAGGCGCGTCGAACGCCAAATCCCGCAAGAAGCCTGAAAAGTCAACGAATAAGGCGGCTGTGCGGCCGCGCATGATACACACAGAGAAATCGCGCAGCCACACCGCCCACGGCAGCCGGAAGCGTTGCAGGACCTTTATCACATGCACCGAGTCCGCCAACATTGAGCTGTTGCCCATGTCTTCAGTGCGCACCGCAGCCTCAATGGTGGACGACTACGACATCATATCACCGCAAGCACTGCCTCCAAAACAAATTAGCTCTAGTCCGCTGCACATCAAGCAGGAGAATGaacagttgcagcagcagcagaacaaCTCGCACCTCTCCAGCGGTCAACACGTGCACTCGGCGCGCAATGGCGACCTCTATGATGCTCAGTTGTTGCTTAGCGCCTCTGCGCTGCGTAAGGAAACGTATGAGAAATTCAATGCCAGCATTGTTAACGACTTGGAGGAGATCCTACGATCCCCCCTCAAATGTGATAGAAACGAACGCCATCGTTTTACCAGCGAGTCGTCCACACAGTTTTTGGTGGAGCAATCCGAAGAGGAGCAGCGAAATATGATAAAAATCGAGCCCACGTCGCCAGATCTGCGTGATATTGTTGTTGGCGGTGGTGCTGCTGGcgtcagcagcggcagcaacagcagcaatgaacGCCGGCCCACGCGTTCATCACGCAATCGCCTCCTCACTGCCAATCGCAAGTATCTGGGATTCGAGACATACCTGCGCCCGGGTTCGGGGCAGCCGCAGCGTAGTGCAGTAACTGGTGGCGGTAGTGACGGCAGCAGCGCTGCTAAGTCCAAAGCCGCCAAGTCGAAGAAAAGCATGGCGCCATCGAAGTCGTACATGCGATACAGCGTGGACGCGTTTAATAAGAGCACAAGCAGCAGCTCGCCCATTGTCAGCGATTCGTACGCCCCGATAGCCGCTGCTGGTGCGGCAATGGCGACGACAGCGGCCGTGTCAATGGCACAGCCGGAACAGCGCAAGCAGCGCTACTTCGAGTGCGAAATGTGCTCAGCGGTGTTTGCCGACCGTGCACAGTTACTTGATCATGTGCCCATACACATTTAA
Protein Sequence: MDRQSYGMHWIHHTAESVKDAGQLLVKMRSSQAEGAIAGNGSVVDGDDEYGGVPTEVDLDQIAAENLIFMARDGQMVGEILNAGTDDNGTVVVRAGDGTPIDCECVMQQVAAVAVAAPVISPDDMVQSAEDAGGGGYVDEYADNTPQMVTEEVITDDWVQHQGEERVEIPAEQIIGSSSQVLLDIEVPLPTVQDEYTLLRPYPCDFCSRRFRKKASLMNHMVAHQNDRPHLCKLCSMRFFRRSDLINHLKAHADAPEPEYETDLMHFVEQEQHQMRHPNDHYYDQDWSMQANPVKMMKNNRKTQNVSGNSSSTSTSTTTTRGRTSRLKPKEENYGLSESMVAPGGRSNGMVATDMVECQQLQASTAAVKLTQHHSPAHHKTYPVVDDSKPFVCQQCGLAFAREKALLSHAKNHRTDSPYECNQCNEMFWDAASLQEHQKSHQFEESNSEYDPGEAEAEETQSESESERLYGEFYCSECGMSFHREDLLRRHSKAHDNAANDGASDHSKDRHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGETFFEEHTIKRHLQSAHPNEMTPNSCILCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVICDVCQEEFPDGRTLSNHRHSHSATASGKLFPCNECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGVDAKRGTFYCSVCSIDLSSSNDLIQHLIQHSDMNTAMQRKPITGPRKYKRRRKLKPHEIARLRRESQQNTNPSENGSVIDMSDFDMDNVDDLLGIAETSPIPNNVTKASKSRRHKIAAKHNGNNNSNGVGNEALLEDVDGHKKLRYNSNSSNSDKLWQMKLINSNTNDESYKSLLSNLENTLQSIDTLVVGSNGDMSGHADEDRKPKYKLESADGCGGSAQRTQEIQLAKLDRKYQVGASNAKSRKKPEKSTNKAAVRPRMIHTEKSRSHTAHGSRKRCRTFITCTESANIELLPMSSVRTAASMVDDYDIISPQALPPKQISSSPLHIKQENEQLQQQQNNSHLSSGQHVHSARNGDLYDAQLLLSASALRKETYEKFNASIVNDLEEILRSPLKCDRNERHRFTSESSTQFLVEQSEEEQRNMIKIEPTSPDLRDIVVGGGAAGVSSGSNSSNERRPTRSSRNRLLTANRKYLGFETYLRPGSGQPQRSAVTGGGSDGSSAAKSKAAKSKKSMAPSKSYMRYSVDAFNKSTSSSSPIVSDSYAPIAAAGAAMATTAAVSMAQPEQRKQRYFECEMCSAVFADRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -