Mcra012407.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melieria crassipennis
Gene Symbol
mrpl14
Assembly
GCA_963668005.1
Location
OY764962.1:48834775-48838361[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.003 0.28 12.3 0.3 1 23 128 151 128 151 0.96
2 13 0.0026 0.25 12.5 0.2 2 23 157 179 156 179 0.94
3 13 0.001 0.094 13.8 4.5 2 23 189 211 188 211 0.95
4 13 1.8e-05 0.0017 19.3 2.5 1 23 400 422 400 422 0.99
5 13 0.00019 0.018 16.1 2.7 1 23 429 452 429 452 0.96
6 13 0.00037 0.035 15.2 4.9 2 23 459 481 458 481 0.96
7 13 1.7e-06 0.00016 22.5 2.4 1 23 486 508 486 508 0.98
8 13 0.0021 0.2 12.8 0.1 1 22 513 534 513 537 0.92
9 13 0.0023 0.22 12.7 1.3 3 23 543 563 542 563 0.99
10 13 0.00017 0.016 16.2 1.5 1 23 569 591 569 591 0.98
11 13 1.1e-06 9.9e-05 23.2 2.6 1 23 597 619 597 619 0.96
12 13 1.4e-06 0.00013 22.8 0.4 1 23 625 647 625 647 0.99
13 13 0.19 18 6.7 0.2 1 23 652 675 652 675 0.93

Sequence Information

Coding Sequence
ATGGAATCCTCCTGCGATATGGACAAGATTTGCCGCGTGTGCATGCGCGACGAGCAGGAAACGTTTGTTATCTTCGAAAAGCAGCGCGTCGAAGAGCAGACATACACGACCGTGGCCGCTATGCTGTGTGAATTGACCGCGTACAAGGTGGAACGCTTTGATGAATTGCCGCAGCTGATTTGTGTTGATTGTCGGCAAGCAGTGCAAAACGCATATCGTCTAAAGCGCAAATGTGAGCAAAGCTATAGGAAATTAGTAGCTTTACTAGGTCGCAGGAAGAGTAGCAACGCAGAGTGGTCTGCCGATGAGCACCTATCAGCGAACTCTGGAAAGCAGGAGTGGCAAGTCGAGAAATGCACACAAACTGATGACACTACGTTGTATCCATGTGAGCGCTGTGATGAGAAGTATTTTACTTTTGATGCACTGCGAGCGCATCGTGAAAGTGACCATAAGGGCAGCGCTATTGTCTGTCGCTTTTGCGCTAAGAGCTTCAACCGCATTGGCTATTTGAAAACGCACATTGCCGTCTTTCATCCTGAGTCGGGCTACAAATCGCACAATCAGTGTCATTTATGTAGGCGACAGTTTACGCGACGAGAGCATATGCGGCGTCATTTGGCAGTTATACATAAAATTGTGGAAATTTCTGATGGCGTTGAAGAGTTGCCCGAGTTGTTGATAGACGTTAATGGAAACGGCGAGCAACAATCAACTGAGTTGGAAAGCGAAGTAAAAGTGGAGGCAGTATCACCTGAGGTACAAACACCTGAACCTTTAGAAATAGACGTTATAGAAACTGTGGAGGAAACTAAACATCAGTTGGGAGAAATAGAGATCAGTGAAAATCCTATAAAGGAGGTAGAAAGTGATGACGATGAGAAAAGTGCAGTTGGTGAGGTCGTTGGGATAGTGGACTCCATAGATGATAGTGAAGATGAAGACGAAAAACCATTATCAAACTTTATAAGCAAAACACCGACAAAAGGATTCCTGGAGGTTTTGCTGAGTGATAACGGCGCTGAGCATAAGCTTACCGAGAATGTCGAGGACATTGCCAAGATCATCAAATGTGAAGAGCCACTGCCCGAAAATGAGCCGCAAGACATGCTTTCCATGGTTAAACGCGGACGTGGGCGTCCTCCTCGCAAAATAAAGGCGATGACGCCCCATAGAAATGCATCACCACTACATGAATACAAATGCAAAGATTGTGATAAAGTTTTCCTACATGAGTCGATGCTGCAACGTCACGTTTCAACACACTCAAATTGCAAAGTGGAGTTTCCTTGTCAgatttgcacaaaatattttgGTAACGCCAAACACTTGGAAAGCCACATGCACAGCGTGCACAATGCGGCGAAAGTTACCAAGTGCAATGAGTGCAATAAAGTGTTTACACACATAACGCAATATAAACGACACAAAGAAACAAAGCACAGTGACATATTACATAAATGTGATATTTGTGAAAAGAACTTCACCACTAAAATGTATCTGCAACGGCACATGGCCATACACGGGCGTAAACGTTACGTGTGTAAAGAATGCTCGCAGAGTTACCTGACCAAGGAGGAATTGAAGGCGCATATTAAGGCAGAAGGACACGACAAACCGATGCTTTGTCCCGAGTGCGGCTTGCGGTGCAAGACGAGCAACATACTGATGGTGCATATGCGGCGTCATAATGGCGAGAAACCGTTCAAGTGTAAATTCTGTAGCAAAGGGTTTCCGCGCATGGATGACTTGCGAGTGCATGAGAAATATCACACCGGTGAAAAGTCACACTTTTGCGAAACGTGCGGCAAAGGCTTTCAACGCAAGTACAACCTCACTATACACATGCGCGTACATACTGGCGAAAAACCCTATAAATGCCCACACTGTCCGCAGGCGTTTGCACAAGGCAACGACTTAAAAGCTCACATACGTCGTCATACTGGCGAGCGATTTCGCTGTGAGGTCTGCGGTGCAGCCTTCCTGCAGGGCTATCAAATACGGCAACACAAGCTCACCGAGCATGGTATTAAAGAGAATCCTCCGACGCAACGTGTGGCAAAGTTTACGTCACGCGAAgagcaagaacaacaaataaaacaaaaccaacgaCGGGAATTGAGTCATGATGTGAATGCAACAGTTGAGTGTAGCGTTGATCCTGAGCCCAGTGACGTTGAAGCTGCGTTGGTAGGCGTACGCGTCcttgcaacaactacaacagtaGCTGTCAATGGAGTGGGGCATACCTGTCAACAGCATCAGTTACAACAGCGACAATTTCATCTCACACCTGCCTGCAATGAAATACGCAAGCTGGCGCGGCTGCGTGTGGTGGACAACAGTGAGATTGGCAAACGTGCCATGGCGGAGGGCAGGCCGCCGCGTTGTATACACGTCTACAACAAACGTGCCGTGGGCTATATCGGTGACAAGGTGCTGGTCGCCATCAAGGGTCAAATGAAGAAGGGTATACTGGTGGGCCTAAAGCAAAATCAGAAACCCAAAATACCAAAGTTCGACAGCAACAATTTGGTGCTCATCGACGACAATGGCAGTCCGCTGGGAACGCGTATCCACGTGCCCGTGCCAACTATACTGCGCACTGTGCTGAAAGAGAAGACACAAGCGAAGGGCGCCGATTACACAAAAGTGCTGGCCATAGCGAGCAGATTTATTTGA
Protein Sequence
MESSCDMDKICRVCMRDEQETFVIFEKQRVEEQTYTTVAAMLCELTAYKVERFDELPQLICVDCRQAVQNAYRLKRKCEQSYRKLVALLGRRKSSNAEWSADEHLSANSGKQEWQVEKCTQTDDTTLYPCERCDEKYFTFDALRAHRESDHKGSAIVCRFCAKSFNRIGYLKTHIAVFHPESGYKSHNQCHLCRRQFTRREHMRRHLAVIHKIVEISDGVEELPELLIDVNGNGEQQSTELESEVKVEAVSPEVQTPEPLEIDVIETVEETKHQLGEIEISENPIKEVESDDDEKSAVGEVVGIVDSIDDSEDEDEKPLSNFISKTPTKGFLEVLLSDNGAEHKLTENVEDIAKIIKCEEPLPENEPQDMLSMVKRGRGRPPRKIKAMTPHRNASPLHEYKCKDCDKVFLHESMLQRHVSTHSNCKVEFPCQICTKYFGNAKHLESHMHSVHNAAKVTKCNECNKVFTHITQYKRHKETKHSDILHKCDICEKNFTTKMYLQRHMAIHGRKRYVCKECSQSYLTKEELKAHIKAEGHDKPMLCPECGLRCKTSNILMVHMRRHNGEKPFKCKFCSKGFPRMDDLRVHEKYHTGEKSHFCETCGKGFQRKYNLTIHMRVHTGEKPYKCPHCPQAFAQGNDLKAHIRRHTGERFRCEVCGAAFLQGYQIRQHKLTEHGIKENPPTQRVAKFTSREEQEQQIKQNQRRELSHDVNATVECSVDPEPSDVEAALVGVRVLATTTTVAVNGVGHTCQQHQLQQRQFHLTPACNEIRKLARLRVVDNSEIGKRAMAEGRPPRCIHVYNKRAVGYIGDKVLVAIKGQMKKGILVGLKQNQKPKIPKFDSNNLVLIDDNGSPLGTRIHVPVPTILRTVLKEKTQAKGADYTKVLAIASRFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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