Basic Information

Gene Symbol
ZBTB41
Assembly
GCA_963082815.1
Location
OY720426.1:6556540-6560697[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 4.4e-05 0.01 18.7 5.4 1 23 152 174 152 174 0.99
2 29 0.031 6.9 9.8 3.8 1 20 180 199 180 203 0.95
3 29 0.066 15 8.7 3.2 3 23 218 238 216 238 0.95
4 29 6.5e-05 0.015 18.2 1.2 1 23 242 264 242 264 0.99
5 29 0.00015 0.034 17.0 3.0 1 23 270 292 270 292 0.97
6 29 2.7 6.2e+02 3.6 2.5 1 19 298 316 298 316 0.89
7 29 0.00089 0.2 14.6 2.3 3 23 337 357 335 357 0.96
8 29 0.0018 0.42 13.6 4.0 1 20 361 380 361 383 0.95
9 29 0.18 40 7.4 6.9 1 23 389 411 389 411 0.97
10 29 0.029 6.5 9.8 3.5 1 23 417 440 417 440 0.92
11 29 0.099 22 8.2 0.9 2 23 458 476 457 476 0.91
12 29 0.018 4 10.5 3.3 1 23 482 504 482 504 0.98
13 29 0.71 1.6e+02 5.5 2.9 1 23 510 533 510 533 0.88
14 29 0.92 2.1e+02 5.1 0.9 2 23 548 566 547 566 0.91
15 29 0.0016 0.37 13.8 2.1 1 23 572 594 572 594 0.97
16 29 0.043 9.6 9.3 1.4 1 23 600 623 600 623 0.97
17 29 5 1.1e+03 2.8 4.5 2 23 636 654 635 654 0.86
18 29 0.0006 0.13 15.1 3.5 1 23 660 682 660 682 0.98
19 29 4.1 9.2e+02 3.1 1.4 1 19 688 706 688 708 0.82
20 29 0.00011 0.025 17.4 3.9 1 23 739 761 739 761 0.97
21 29 0.026 5.8 10.0 0.8 1 23 767 790 767 790 0.97
22 29 0.18 40 7.4 1.8 1 23 1166 1188 1166 1188 0.97
23 29 0.0045 1 12.4 2.2 1 23 1194 1216 1194 1216 0.98
24 29 0.83 1.9e+02 5.3 5.5 1 23 1222 1244 1222 1244 0.98
25 29 0.0044 0.99 12.4 3.2 1 23 1250 1272 1250 1272 0.98
26 29 0.0046 1 12.4 0.4 1 23 1278 1300 1278 1300 0.97
27 29 0.00021 0.047 16.6 4.7 1 23 1306 1328 1306 1328 0.97
28 29 0.004 0.89 12.5 0.9 1 23 1334 1356 1334 1356 0.97
29 29 0.068 15 8.7 1.2 1 23 1362 1384 1362 1384 0.97

Sequence Information

Coding Sequence
ATGAAGACTCATACTAATGAAGAATCATTGAAACACCCGGCATGCGACTATTCGGCAAatgaaatgtttgaaacaaCCGATTCTATCGTTGCTGCATATCAAAACCTAAAAGATGATTCTGAAAATACAGAAGAAGATGAGCACAAGGatgttgaattaaaaaacaaagagaCGTATGTAAATAAGGCAATCAAAGTTGAAACCGAAACAAACTCAAACATAATTTGTTCGACCCCCGAACCTCACTTTGAAATGTTAAGCAATGCTTCTGAAGAAGAGACGTGTGAACCTCATTTTGAAGACATTAAAATCGAAATTCTTGAAGCAACCAACCCAATTGTTGCTGTAAATTTTAAACTGGATTTCGAAGAAGAAGAGTGTAAGAATAATGTTCAAAGCCAGGCAAATGAAGGTTTGTTCTGTAGTTCTGATATGAAGCATGAAGGGAAAATTTACAAATGCACACTTTGTCCTAAACAGTACACTCGTAAACACTCGCTCAAATATCATATGAACTCTCATACGGGAGAGCAACCTTTTAAGTGTAAGGAATGTAATTACGCAACCAAAACACATAAAGAACTACGAACTCATTATTGGTCTAAGCATAATAAGCCCATGGAAATGGAAGAACCGAATCAAAGCAGTATTTGTTCCATTTGTCATCGATATTGCGGTACATCTGCTCGTCTGAAGAAACACATGTTAGCACATGAAAAGCCATACAAATGTAATATATGTAACATGAGACTTTCTTACCGTGAAAGTCTAAACCGTCATATTTTACGTCATACTGGCATTAAACGATTTGCGTGTCATATTTGTCAAAATACTTATACGACCAAGGCTTCGCTCCAATATCATATGAAATctcataccggagaaaaaccatATCGTTGTAAAGAATGCGACTATTCGGCACACTCACACCAGTTATTACGATATCATTGTTGGTCTAGGCATAATAAGCCCACGGAAATGGAAGGAGAACCGAATCAAAACAGTATTTGTTCCATTTGTGATAAATATTGTGGCACACCTATTCATCTAAAAAAACATATGTCAGTACATACAAAACCATACAAATGTAAGATATGCAACATGAACTTTTCATACCGTCAAAGTCTAAACCGTCAtgttttatgtcatactggcaTAAAACGATTTGCGTGTCATATTTGTCACAATCGTTACACGACAAAGGTTTCGCTCGAATGTCATATAAAAACAcacacaggagaaaaaccgtatCCTTGCAAAGAATGTGACTTTGCAGGAAAGACGAGGTCTGAATTACGAAAACATTGTAAACGCAAACATTTGATGGACGAAGACACTAGGAAAATTCAGACTGAACAAAAGAAGGCCACTGTTTGTccaatttgcaacaaaaaaatatttaatttaagacGTCACATGTTAACTCACACGGATGAGAAACCTTTTGAGTGTAACATTTGTCACATTCGTTATAGGAGTAAAAATTCGCTTGAATTTCACTTGAAGTCGCATACGGGAGAGAAGCCGTTTCGTTGCACAGAATGTGATTATTCCGCAAAGACTGCCAAACAAGTACGATACCATTGCAATCGTATTCATGCAGATGAAATAGCACGATTAAATAGTGCTAGGATTAAAAAAACTTGCCCAATTTGCAACAAGAAAATACGTGAATTAAATCGTCATTTGTTAACACACACGGGCGAGAAACCTTTCGTGTGCAATATTTGTCAGAAACGTTACACAAGTAAAAATTCACTCGAATTTCATTTAAAGTcacatactggagaaaaaccgtttcgTTGCACAGAGTGCGATTATTCGGCAAAGATGAACAAACAAGTACGAGAACATTATAATCGTATGCATACAGTTAAAATGGCAAACTCagacattaaaaaaactgtttgTCCAATTTGCAACAAAAGAATACTTCATTTAAAGCGTCATATGTTGACTCACACGGGTGAGAAACCTTTCGAGTGCAATATTTGTCACAATCGTTACACAACTAAAAACTCGCTCGAGTATCATATAAAAtcgcatacaggagaaaaaccgtttcgTTGCACAGAATGCGATTATTCGGCAAAGACCGACAAACGGATACGACACCATTATAGTTGTAAACATACAGATAAAGTGAAACCCACTACAACAAGCAAAACTTCTCACAAGAACAAGAACATTTCTCACCCAGGTGTTTTAAAACGATTCGATTGTGACATTTGTCAGAAACGTTTCAGAAATAGAGCCTTTCTCATTCATCATAGAAAGAcccatactggagaaaaatcatttaaatgcACGGATTGTGACTATTTAGCAATTGACAACAACACACTACAAAATCATTACAAAAATAACCATACATTTTTCGTTATAGAAGAAGTTAATGTTGAACAACCTCATTTAGATAATGATCGAAGTAAAATTCTTGAAACAATCAATCCCACTGTTGCTGTCAATcggaatttaaaatgtaattctgAAAATGCAGAAAACGACCAGCATAATGCTTCTGAAGAAGAGGCGCTTGAACCTCACTTTCAGAACATTAAAATCGAAATTCTAGAAGCAACTTCTGAGCCTCAACTTGCCACTTTAAGCAATGCTTCTAAAGAAGAGGCACTTGAACCTCACCTTCGAAATATCAAAAGCAACATTTTTGAAGTAACGGACCCAACTTCCGAACTTTGCTTCGATGTATTAAACAATGTTCCTAAAGAAGACGTGGGTGAACCTCACTTCCAAAACTTTAAAAGCGAAATTCTGGAAGCAACGGACCCACTTTCTGAAACTCACTTAGACATTTTAAACAATGCTTCTGAGGAAAACGTGTGTGAACCTCACCTTCAAAACCTTAAAAGCAATATTTGTGAAGCAATCGACCCAACTGTAAATTTGGAATGGAATTTTGAAGAATCTCAACATATACAAAACAGCACACACGAGGAGGTCGAAGCAAAAGACAAAACAACACATGTAAATACGCATACCaaagttaaaactaaaacaagcgAAGCTCCTAATTTAAAAGAACAGCCCAAAAACATACAAGCAATTAAGCCCGAGGAAGTCGAAATAAAAGACGAAGATAATTCCATTTTTACTGCAGTCCGAGAGTACCTAACTTCTGAACCTGGTTTTGAAATGAATGAATCTCACTTTCAAAACCTTACAAGCAACATTTTCGAAGCAACCCGCCCAGTTAATTTTGAACAGCATTTTGAAGAACCCGAACATATACAAAACAGCACACACGAGGAGGAAGTAAAAGACAAAACGACAAATGTAAATACACATACCgaagttaaaactaaaacaagcgAAGCTCTGTATTTAAAAGAACAACTCAGAAACATACAAGCAATTAAGCCCGAGGAAGTCCAAATAAAGGGCAAGTTAACATACAAAGATAATCCGGTTTTTACTGCAGTGCAAGAAGACGAGGACGATCTTGGAAAGCGCTCGCGCACTACAGCAAAACAACCGTATGCTTGTAGCTTATGTGAATTTGAGACCGCTCATGGAGATCATTTTAAATGGCATATGCTTAGCCATAAGAGAGACAAGTTATTTACTTGCAATTTATGCGAATTTAAAACCgcatataaaagaaatttaagaacGCACATGTACATTCATATGGATGATAAACCGTTTACTTGTAGTTCGTGTAACTTTAAAACCGCATGTAGGAGAAGCCTCAAGAAACATATGCGCATACATTCGGGAGAAAAACCCTTTGTTTGTAGTGTATGTGAATTTAAGACGGCACATAAACACAGTTTGGAACAACATTTACGTATTCATACGGGGGAAGCTTTATTCGCTTGTACGTATTGTGAATATAAGAGTATAACTAAAGGCAGCCTGGATAaccatatgagtattcatacggGTGAAAAAGCGTTTGCTTGTCATTTATGCGATTTTAAGACTACTCGTAGGAGTAATCTCAACCACCACATGCTTGTTCATACTGAAGAAAAACCGTTCGCTTGCGACCTATGCAATTTTCGGAGTAAACGTAAATACGCTGTTACAAAGCATATGCTTGTTCATTCTGAAAAAAAGCAGTTCGCTTGTGATTTATGCGAATTTAAAACAGCACGCAAATGCAGTTTACAAGGTCACATGGCTAGTCACGGGTGA
Protein Sequence
MKTHTNEESLKHPACDYSANEMFETTDSIVAAYQNLKDDSENTEEDEHKDVELKNKETYVNKAIKVETETNSNIICSTPEPHFEMLSNASEEETCEPHFEDIKIEILEATNPIVAVNFKLDFEEEECKNNVQSQANEGLFCSSDMKHEGKIYKCTLCPKQYTRKHSLKYHMNSHTGEQPFKCKECNYATKTHKELRTHYWSKHNKPMEMEEPNQSSICSICHRYCGTSARLKKHMLAHEKPYKCNICNMRLSYRESLNRHILRHTGIKRFACHICQNTYTTKASLQYHMKSHTGEKPYRCKECDYSAHSHQLLRYHCWSRHNKPTEMEGEPNQNSICSICDKYCGTPIHLKKHMSVHTKPYKCKICNMNFSYRQSLNRHVLCHTGIKRFACHICHNRYTTKVSLECHIKTHTGEKPYPCKECDFAGKTRSELRKHCKRKHLMDEDTRKIQTEQKKATVCPICNKKIFNLRRHMLTHTDEKPFECNICHIRYRSKNSLEFHLKSHTGEKPFRCTECDYSAKTAKQVRYHCNRIHADEIARLNSARIKKTCPICNKKIRELNRHLLTHTGEKPFVCNICQKRYTSKNSLEFHLKSHTGEKPFRCTECDYSAKMNKQVREHYNRMHTVKMANSDIKKTVCPICNKRILHLKRHMLTHTGEKPFECNICHNRYTTKNSLEYHIKSHTGEKPFRCTECDYSAKTDKRIRHHYSCKHTDKVKPTTTSKTSHKNKNISHPGVLKRFDCDICQKRFRNRAFLIHHRKTHTGEKSFKCTDCDYLAIDNNTLQNHYKNNHTFFVIEEVNVEQPHLDNDRSKILETINPTVAVNRNLKCNSENAENDQHNASEEEALEPHFQNIKIEILEATSEPQLATLSNASKEEALEPHLRNIKSNIFEVTDPTSELCFDVLNNVPKEDVGEPHFQNFKSEILEATDPLSETHLDILNNASEENVCEPHLQNLKSNICEAIDPTVNLEWNFEESQHIQNSTHEEVEAKDKTTHVNTHTKVKTKTSEAPNLKEQPKNIQAIKPEEVEIKDEDNSIFTAVREYLTSEPGFEMNESHFQNLTSNIFEATRPVNFEQHFEEPEHIQNSTHEEEVKDKTTNVNTHTEVKTKTSEALYLKEQLRNIQAIKPEEVQIKGKLTYKDNPVFTAVQEDEDDLGKRSRTTAKQPYACSLCEFETAHGDHFKWHMLSHKRDKLFTCNLCEFKTAYKRNLRTHMYIHMDDKPFTCSSCNFKTACRRSLKKHMRIHSGEKPFVCSVCEFKTAHKHSLEQHLRIHTGEALFACTYCEYKSITKGSLDNHMSIHTGEKAFACHLCDFKTTRRSNLNHHMLVHTEEKPFACDLCNFRSKRKYAVTKHMLVHSEKKQFACDLCEFKTARKCSLQGHMASHG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-