Basic Information

Insect: Melanotus villosus
Gene Symbol: EGR1
Assembly: GCA_963082815.1
Location: OY720420.1:17256441-17266591[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 1.8 4e+02 4.2 0.1 8 23 164 179 163 179 0.92

2 13 7.4e-05 0.017 18.0 4.5 1 23 185 207 185 207 0.98

3 13 7.5e-07 0.00017 24.3 2.2 2 23 214 235 213 235 0.97

4 13 1.8e-06 0.00041 23.0 0.4 3 23 243 263 241 263 0.98

5 13 2.2e-06 0.0005 22.8 0.8 1 23 438 460 438 460 0.98

6 13 1.6e-07 3.7e-05 26.4 1.8 1 23 466 488 466 488 0.95

7 13 2.4e-06 0.00054 22.7 2.3 1 23 494 516 494 516 0.96

8 13 8e-08 1.8e-05 27.3 1.4 1 23 522 544 522 544 0.98

9 13 8.7e-07 0.0002 24.1 2.1 1 23 553 575 553 575 0.96

10 13 2e-06 0.00044 23.0 2.6 1 23 581 603 581 603 0.98

11 13 2.7e-06 0.0006 22.5 0.1 1 23 609 631 609 631 0.98

12 13 2.6e-06 0.0006 22.5 2.2 1 23 637 659 637 659 0.99

13 13 2e-05 0.0046 19.8 0.3 1 22 665 686 665 689 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	1.8	4e+02	4.2	0.1	8	23	164	179	163	179	0.92
2	13	7.4e-05	0.017	18.0	4.5	1	23	185	207	185	207	0.98
3	13	7.5e-07	0.00017	24.3	2.2	2	23	214	235	213	235	0.97
4	13	1.8e-06	0.00041	23.0	0.4	3	23	243	263	241	263	0.98
5	13	2.2e-06	0.0005	22.8	0.8	1	23	438	460	438	460	0.98
6	13	1.6e-07	3.7e-05	26.4	1.8	1	23	466	488	466	488	0.95
7	13	2.4e-06	0.00054	22.7	2.3	1	23	494	516	494	516	0.96
8	13	8e-08	1.8e-05	27.3	1.4	1	23	522	544	522	544	0.98
9	13	8.7e-07	0.0002	24.1	2.1	1	23	553	575	553	575	0.96
10	13	2e-06	0.00044	23.0	2.6	1	23	581	603	581	603	0.98
11	13	2.7e-06	0.0006	22.5	0.1	1	23	609	631	609	631	0.98
12	13	2.6e-06	0.0006	22.5	2.2	1	23	637	659	637	659	0.99
13	13	2e-05	0.0046	19.8	0.3	1	22	665	686	665	689	0.91

Sequence Information

Coding Sequence: ATGGGTGGTGAAGACCTTCCCTTACGGGCCGGTCAACGGATTGGTGGTGAAGACCTTCCCTTTCGGTCCGGTCAGCGGACCGCGGTTGAAGAATTTCCCTTACGGGCCGGTCAACGGATCGGTTTAAGGCTTGCGGACGGTCAGGTTCAGAACGATGGCTTACCTGATCAGATATGCGATAAATGTATAGCACAAGTAGTAATTGCTTATAAATTTAAGCAGAGGTGTGAAAAAGTCGATGCTACATTACGGACTTATCAACAAACAACCGAACCAAAGGCAACTATAGATATTGAAAACGTACAAATAGAACCTAagcaagaaattaaagaaactgAAGAGGTACAAACAAACGTTGAATGTTCACCTCCGGTAGAACTTTCAAATAACACCCTTAATGAAAATTCTTCAAGTAATTATAACCGTAAGGTATTACTGGAAAGAAAAGTTTTATGCGAAGAATCATTTGTCCAAGACAATAAAGGAAGAAAGGGATTTATAAGATCAGACGACTTATTGAGGCACTGCCGCATTCATACAGGTGAAAGACCATTTGTTTGTAAAACCTGTAACAaaggttttaaacaaaaatttcatcTATCGGAACACGAACGATCACACGGAGGCAAACGGGATCTTACCTGCAAGGAATGtggaaaaagtttcgtGAGACATGGAGTTTTACGAACTCATATGCGAACCCACACTGGTTTAAAACCATATGGTTGTAGTTTATGTCCAAAAAGTTTTGTTGGCTCTGATACACTTACAAAACATATGAGAACTCATACAGGTGAAAAACCCTACTGTTGTAGACTAAAGctacaaatatataaaactattaTCAGACCGGTAGTGACATATGGAACAGAAACATGGACCCTAactaaaaaagaagaggaagagctaaaagtatttgaaagaaaaatattacgaagaaTAATGGGACCAGTACGAACAGAAGAAGATGAATACAGGCCGAGAATGAACTTTGAACTAAGAGAACAAATGAACGGGGAAGATATTGTTACATATATAACGgcacaaagaataaaatggttagGGCATGTAATGAGAGCAGACAAAAaaagagtaataaaaataataacagaatggacACCAACcgaaaatagaagaagaggcAGACCCAGTCTGAGATGGATGGATGAGGTACAAGAAGACCTAAAGAGGCTAGGGATAAAGAAGTGGAGAGACAAATGCGAAAAGAGGAAGGAATGGGCAAAGATAGCAGAAGAAGCTAGAACGAATCAATTACAAGCCCATTTCCGTATACACTCGGGAGAACGTCCGTATGTATGTAACATTTGTTCCAAAGCATTTACTCAACAACACGGTCTTAATGTTCACTTGCTTAGTCATACCGGTGAACGTCCATTTCTTTGTGCAACTTGTGGCAAATCATTTACTAGATCGGACGATCTCAAGAAACATACCCGAACGCATAGTCAAGAAAGGCCGTATTTATGTACACTTTGTCCAAAAGCTTTTACACAGTCATTTCATTTATCTGAACATATGCGTACTCACACAAATGAcaagGAATTCTCCTGTGGCATTTGCAATAAAACGTTTTCTCGGAACGGATCTCTTCGATCACATTTACGAACCCATACGCAAAGTTATGTGGAGAAGCAACATGCTTGTAGCATATGTGATAAAAGGTTTAGTGTTAGTTATTCTTTGAATAAACATATGCTTACCCATACAGGAGAAAGACCATATTCCTGCCATTTATGTTCAAAGgCCTTTACACAATCAGGGCATCTCGAAGCACATCTAAAAATACATAGTGGAGAGAAACCCTACATTTGTCAAGTGTGTGGAAAAGGATTTGCAGTTAGTTCTCGTTTAACAGTACATATGCGAAGTCATACCGGTGAAAAACCATATACTTGTTCTTTATGTGGAAAAGGCTGCACTACATCTACCATGTTAAAAATTCATATACGAACCCATACTGGTGAAACACCGTATCCTTGTCCGACTTGTCCAAAAGCATTTTCAAGGTCTGATCTGTTAAGTCTGCATCGCAAAAATAACAGTCATTAA
Protein Sequence: MGGEDLPLRAGQRIGGEDLPFRSGQRTAVEEFPLRAGQRIGLRLADGQVQNDGLPDQICDKCIAQVVIAYKFKQRCEKVDATLRTYQQTTEPKATIDIENVQIEPKQEIKETEEVQTNVECSPPVELSNNTLNENSSSNYNRKVLLERKVLCEESFVQDNKGRKGFIRSDDLLRHCRIHTGERPFVCKTCNKGFKQKFHLSEHERSHGGKRDLTCKECGKSFVRHGVLRTHMRTHTGLKPYGCSLCPKSFVGSDTLTKHMRTHTGEKPYCCRLKLQIYKTIIRPVVTYGTETWTLTKKEEEELKVFERKILRRIMGPVRTEEDEYRPRMNFELREQMNGEDIVTYITAQRIKWLGHVMRADKKRVIKIITEWTPTENRRRGRPSLRWMDEVQEDLKRLGIKKWRDKCEKRKEWAKIAEEARTNQLQAHFRIHSGERPYVCNICSKAFTQQHGLNVHLLSHTGERPFLCATCGKSFTRSDDLKKHTRTHSQERPYLCTLCPKAFTQSFHLSEHMRTHTNDKEFSCGICNKTFSRNGSLRSHLRTHTQSYVEKQHACSICDKRFSVSYSLNKHMLTHTGERPYSCHLCSKAFTQSGHLEAHLKIHSGEKPYICQVCGKGFAVSSRLTVHMRSHTGEKPYTCSLCGKGCTTSTMLKIHIRTHTGETPYPCPTCPKAFSRSDLLSLHRKNNSH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -