Basic Information

Insect: Melanostoma scalare
Gene Symbol: L
Assembly: GCA_949752695.1
Location: OX456984.1:227919148-227929125[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.3e-06 0.0014 20.8 1.7 1 23 178 200 178 200 0.98

2 16 0.44 1.1e+02 5.4 5.8 1 23 206 228 206 228 0.98

3 16 2.3e-07 6e-05 25.1 3.1 1 23 234 256 234 256 0.99

4 16 1.1e-05 0.0028 19.9 0.3 1 23 262 284 262 284 0.98

5 16 4.3 1.1e+03 2.2 0.2 3 23 348 370 346 370 0.84

6 16 0.0039 1 11.8 0.4 2 23 387 409 386 409 0.97

7 16 0.051 13 8.3 1.3 1 23 490 512 490 512 0.97

8 16 0.0012 0.32 13.4 1.1 2 23 520 541 519 541 0.95

9 16 2.1e-05 0.0054 19.0 0.8 1 23 549 574 549 574 0.94

10 16 0.0014 0.36 13.2 2.9 1 23 666 688 666 689 0.96

11 16 0.001 0.26 13.7 4.6 2 23 869 891 868 891 0.96

12 16 0.12 30 7.2 0.1 1 23 897 919 897 919 0.92

13 16 7.5 1.9e+03 1.5 1.4 2 23 927 948 927 948 0.95

14 16 4.9 1.3e+03 2.1 0.6 2 23 1038 1059 1038 1059 0.92

15 16 0.0068 1.8 11.1 0.0 1 23 1069 1091 1069 1091 0.96

16 16 2.2 5.7e+02 3.2 1.2 1 23 1098 1120 1098 1120 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.3e-06	0.0014	20.8	1.7	1	23	178	200	178	200	0.98
2	16	0.44	1.1e+02	5.4	5.8	1	23	206	228	206	228	0.98
3	16	2.3e-07	6e-05	25.1	3.1	1	23	234	256	234	256	0.99
4	16	1.1e-05	0.0028	19.9	0.3	1	23	262	284	262	284	0.98
5	16	4.3	1.1e+03	2.2	0.2	3	23	348	370	346	370	0.84
6	16	0.0039	1	11.8	0.4	2	23	387	409	386	409	0.97
7	16	0.051	13	8.3	1.3	1	23	490	512	490	512	0.97
8	16	0.0012	0.32	13.4	1.1	2	23	520	541	519	541	0.95
9	16	2.1e-05	0.0054	19.0	0.8	1	23	549	574	549	574	0.94
10	16	0.0014	0.36	13.2	2.9	1	23	666	688	666	689	0.96
11	16	0.001	0.26	13.7	4.6	2	23	869	891	868	891	0.96
12	16	0.12	30	7.2	0.1	1	23	897	919	897	919	0.92
13	16	7.5	1.9e+03	1.5	1.4	2	23	927	948	927	948	0.95
14	16	4.9	1.3e+03	2.1	0.6	2	23	1038	1059	1038	1059	0.92
15	16	0.0068	1.8	11.1	0.0	1	23	1069	1091	1069	1091	0.96
16	16	2.2	5.7e+02	3.2	1.2	1	23	1098	1120	1098	1120	0.92

Sequence Information

Coding Sequence: ATGTCGGATGGGACAATTACTCCAAACTCGCTGCACCACCATCATCttcatcaccatcatcaccatcatcaacAGAGGCTGCATCAACATTTGCAGTACCAGTGTGAACAGCAAAACAGCGGTGGTCACAACCGCGACAGGCATCACAATCGACGTGTTTCAGCCTTAAATGGAGCAACTGCCACCGGTGTTGGTGTCACTGGCGAGGACGACGACAATGATGACGACGAGGCAGGGGATGCCGCAGACGAAGATGACGACGCCGCAAATTCTAGCGAAGAAAGGGTTTTCCTCTCATCGAATGGTGGCGGTGGTGTTGGTGGCTGTGGTGCCaatgatgctgctgctgctgccacCAGCAACACAACCACTTCCACCACCACCGCAAGTAGCATCATCAGTGGCGCAACCGGCGGCGAACATTCCGTGAAAATACCAACGAAATTGCGGAAAATCGATAGGGATTCGGCAAAGTTGTTGGATAAGTTGACAAGTGATGGCATTAAGAGCGCGACCGACCGCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTCAAGAAGCATGAACAGaGCCATGCGGAGCACCTTCCATTCAAATGCGACTACTGTGCGCGGCTTTTCAAGCACAAGAGGTCTCGTGACAGGCACACCAAACTGCATACCGGAGATAGGCGATACAGGTGTCCACATTGTGAAGCGGCATTTTCAAGGAGCGACCATCTAAAGATACACATGAAAACTCATGATAACCAAAAACCGTTTCAATGCACCATTTGCAATCGAGGCTACAATACTGCCGCAGCTCTGACATCGCACATGCAAAATCACAAGAAGCAAGCTGCCTTACTGGCTGCTGGAGGAAACCCTGCCGCACTGAATTACAGCCCACGTTCAACTGGTTCCGGTTCAAGCAATGGCAGTCTACAAAAACGTCGTTACACATCAGTTGCGAACACCAAGAGCCCCAGTCCAAGTACACTAGAGTATGCCAAGCGTATGCGAAGTTCCTTTATCGCCTGCATGTATTGTACGAAATCCGATTTCTCGTCGATGGAACAGTTAAGTAGTCACATTCAAGCAATGCATGAGAAAGAAGCACTTGCCAATCAGCCTGCTAACAGTGGATTCCAAATGTCGTGCGAGTACTGCACCATGAAATTTCCCAGTATTCCCGCAATGTTCCAGCACATGCGAACCACACATATTGACCGCCTATCGAGTCCTAGCAGTTATTTTGAACACTTCAACCGGATCGCGGCATCTGGCTCGTTTAGTCCTCGATTACCGACTCCCAAGTCTCACGAAACTAAGGTCAAAGTCGAAGAACCGAGTCCTAAGGGTGATGAAAAGGGCGACGAGGAACCAACAGATTTAAGCCAAAACAGACGTTCCGTTCCGACACCTTCACAAGATTCTACCGAGGCTGCCGAAAGACCGGGTGTGTTCTTTTGCAATCAATGCAGCGACGGTTTTCCAGACTTTGACAGTTTCCGCAATCACCTCAAGTCACATATTGTACAAGGACTCAACTTGGTTTGTCATCACTGCGGCCAGACATTACGTGACCAGCCCGAATATGAAAGGCACGTTGTTTCACACTTCCTTATCACTTGCTCCGAATACTCATGCACAGAGAAGAACTGCAATAAATCCTTTTCTAAGCCAGATGAACTGCAAAAACACCTCTTGGAGAACCACATCCAGGCCATGTTCAAGTGTCTCCTTTGCTCGGATCTTTTCGAAACCAAGGTGGCAGTTCAGGTCCACTTTGCTTGCATTCATTCTCCAGAAAAGAAGATATTCCGTTGTTCTGCCTGCATGGAAACCTTTCAAGGAGAACAGGACTTTCACATTCATGTCAAGACTCGGCATCAGACTATAGTCGGTTCACCCATCCAGTGTATGTTCTGCAGGGCTGTTTGCTCCACCGAACTTGAGATGCATTTTCACTTGGCTGCTCATGCCCGACAGTTCCGCTGTCCATCGTGTCCAGAGACGTTCCATGTCGAGTTTTTGCTCGACCGCCACATGCAAACTCACCACCATGGACAGAAAGAGGACACTTCTCCGCCTGTCAATCAATCTCCAGTGAACTCCATCAATCCTCTTTACATGAGTGCCCTCTTCAACAAACCACCTCCCTCAACTCAGAACAATAACAATAGCATTTTGGATTACAACGCTTTCGCAATGGGTAAGAGCATATTCGCCAATGCCTCAGGGAACAAGTTCTACAATCCCCTCCAGGTGGACACTAGTCCAGCGATGAAGCATCCCTCTTTGGTGTACGCCAGCTTGAACCAACGATACTTTGACACCAATCGAACAATTCTAGAGATGTACAGCCAGCATCAGCAGGATAAACTTGTTGGCAACAGCTCATCAACTGGCATGTTCAGCAGCCCGAGTAATACCAACAGAAATTCTCAAAAGTCTCAACAAGAAGGCAACAAGTCCTCCGACCGAGTTTTGAGTGGAGGTTTCAGTTGCGGCATGTGTGAACGCAACGATTTCCGCACCGAAGCCGAAATTCACTCACATCGCAAGATCGTGCACAATCTCAAGACCGGTGTGAGTCTGCGCTGTGCTTACTGCAGCGGCAACTTCAAATCTCGCAGTGAACTGGAACATCACATGAAGACTTGCCACAATTCCACTGGAAAACACAAATGCCTCATTTGTGATGAGATCTTCCCATCGCCTGCTATACTTGCAGAACACAAGTTGCAACACTCCAAAGTGGGACAGTCAGGAAAGTGCTGCCACTGCGCCAAAGCTTTACCGGATGTCACCGCTTTCAAAGGTCATCTCCTTGAGCACAACACTGAAGGACAGATGCCAGTTCAATGCATTTGCTGTCGTCAAACTCTGCATTCCGACTTTGAGATCGGTCTCCATGCCAAGTTCCACACAAAATCGTCATCTGTGTCAGAGAGCGTCTGCGCGCTTTGCTTGGAAACTATACCGAACACAACCGACGCCAAGGTGTGCGAGAAATGCTGCCGCAAACATAATCTAAGCAACAAATTCTCAAACCATCAGCGCAACTTCGACAGCGGGTCCGGACAGCCAAACTTCGTGGAGAATCGATGTAACCTCTGCAATGTCATCATGCCGCATTCTCAGAAACTCCAAGAACACTTGGTCGAGCACACTTTTGCCGGTTGCGAGGATCGAGGCTTCTCATGTTACATCTGTTCGGCGGTGTTTACAGCACCTGCAGGCTTGTTGGCCCACATGACCGAGCACGGAGCCAATTCGCGTCCGTACGACTGCAACCTTTGCAGTGATAAATTCTATTTCCGAGCGGAGTTGGATCATCATCTGGTGGATCATGAAACACGTGACCGATCAAAGAAACCACCCACTAGAGACCACACCCCACCCACAGAAGATAAGAAAGCTTTCATAGAACCATCTCCAGCCGAGCAACCAACTCCTAAGCTCGAACCTAAGAATGAAGTCATGGAAGAAAAAACACCCGACGAAGATGACGACGAATACATCGAGGTAGAGAAGGTTCCAGACCCCTCACAAGAGGCCAGCACGCGTTCCTCAGCAGAAAAGGACGACTAG
Protein Sequence: MSDGTITPNSLHHHHLHHHHHHHQQRLHQHLQYQCEQQNSGGHNRDRHHNRRVSALNGATATGVGVTGEDDDNDDDEAGDAADEDDDAANSSEERVFLSSNGGGGVGGCGANDAAAAATSNTTTSTTTASSIISGATGGEHSVKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPAALNYSPRSTGSGSSNGSLQKRRYTSVANTKSPSPSTLEYAKRMRSSFIACMYCTKSDFSSMEQLSSHIQAMHEKEALANQPANSGFQMSCEYCTMKFPSIPAMFQHMRTTHIDRLSSPSSYFEHFNRIAASGSFSPRLPTPKSHETKVKVEEPSPKGDEKGDEEPTDLSQNRRSVPTPSQDSTEAAERPGVFFCNQCSDGFPDFDSFRNHLKSHIVQGLNLVCHHCGQTLRDQPEYERHVVSHFLITCSEYSCTEKNCNKSFSKPDELQKHLLENHIQAMFKCLLCSDLFETKVAVQVHFACIHSPEKKIFRCSACMETFQGEQDFHIHVKTRHQTIVGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHHGQKEDTSPPVNQSPVNSINPLYMSALFNKPPPSTQNNNNSILDYNAFAMGKSIFANASGNKFYNPLQVDTSPAMKHPSLVYASLNQRYFDTNRTILEMYSQHQQDKLVGNSSSTGMFSSPSNTNRNSQKSQQEGNKSSDRVLSGGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCCHCAKALPDVTAFKGHLLEHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSVSESVCALCLETIPNTTDAKVCEKCCRKHNLSNKFSNHQRNFDSGSGQPNFVENRCNLCNVIMPHSQKLQEHLVEHTFAGCEDRGFSCYICSAVFTAPAGLLAHMTEHGANSRPYDCNLCSDKFYFRAELDHHLVDHETRDRSKKPPTRDHTPPTEDKKAFIEPSPAEQPTPKLEPKNEVMEEKTPDEDDDEYIEVEKVPDPSQEASTRSSAEKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: -
80% Identity: -