Msca014623.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melanostoma scalare
Gene Symbol
PGRP-LD
Assembly
GCA_949752695.1
Location
OX456984.1:178445872-178460600[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.027 7.1 9.2 5.5 1 21 204 224 204 226 0.95
2 11 1.1e-06 0.00029 23.0 0.3 1 23 232 254 232 254 0.99
3 11 0.0025 0.65 12.4 3.1 1 23 260 283 260 283 0.96
4 11 0.054 14 8.2 3.9 1 21 289 309 289 311 0.95
5 11 0.00013 0.033 16.5 2.7 1 23 317 339 317 339 0.99
6 11 0.00024 0.061 15.7 2.9 1 23 345 367 345 367 0.98
7 11 0.00032 0.082 15.3 3.7 1 23 375 398 375 398 0.98
8 11 0.0025 0.64 12.5 4.6 2 23 405 426 404 426 0.96
9 11 0.0032 0.83 12.1 0.5 1 23 432 454 432 454 0.98
10 11 2e-05 0.005 19.1 2.6 1 23 460 483 460 483 0.96
11 11 4.4e-08 1.1e-05 27.4 1.5 1 23 497 519 497 519 0.97

Sequence Information

Coding Sequence
ATGTCTCGACTAACAACAGATATGCAGATCAAGATGGAAAGCAATGATTTACAAACATACTTGGATACATTTAATAAAGAAATAGAAGAAGGCAATCGAAGTCTGAGTGCAAGTCTAGTGGATGCGGCTGATTTGATGAGTTCCAATAGTAAAGATGGTGACGAGGATGGCGGAACATACTTTATTGATCAAGCAGGAAATTACTATTACCAAGCAACCAAAGATTCCGACCCTATACCAACAGATCCTCCTGAAAATGTGCAAATTGTTGATGACGAAAGTGAAGGCGAAGAGattgagttttcaaaaacaatagttaaaaacagaaaaagctactctaaaaataaaaagtcaagAGGCGACGATGATAGTATAAACTACGTTTATGCACTTGATGATAATGAAGGAGAAGTCGATGAGGAGGgaaatgaaattgaagaagaaCACGATATCAACGATCAAGAAAACGAAGAAGACAATGAGATGGAGGACTCTGATGATGATAAAGTCTTTGAATtcgatgaaaatgaagaaacatcgtCTAAAAAATCTGATTTCGTCGAACCAAAAGTTGTGATGCTCAAACCAAAAAATGGGACAGGAATAACGCATCAGTGCCCTCACTGTGAGTACGTTTCTTCTAAGAGATATTTGCTAGCTCGTCATTTGAAATGCCATTCCGATGAGCGTCCTTACAAATGTCCTGTTTGCGAACGAGGTTTTAAGACAAATGCATCGCTGCAAAATCACGCAAACACACACACCGGCAACAAGCCACATCGTTGTAAATTTTGCGTAAGTACTTTTACTACCTCTGGAGAGCTAGTGCGACATGTTCGTTACAAACACACTCATGAAAAACCACATAAATGCTTTGAATGTGACTATGCTAGCGTGGAATTAAGCAAATTAAAGCGTCATATACGTTGCCACACAGGAGAACGCCCATACCAATGTCCACACTGTACCTATGCATCACCAGACACCTTCAAGCTTAAGCGTCATTTGCGAACTCACACTGGAGAGAAACCATACGAGTGCGATATCTGCCATTCAAAATTTACCCAGTCGAATTCATTGAAACAACACAAATTAATCCATAGTGTTGGCGATAAGCCTGTATTCCAGTGCCATCTCTGTCCAACTACCTGTGGTCGCAAGACTGATTTGAGAATACATATTCAGAAGCTGCACACTTCTGAGCGTCCGCTAACTTGTAGGAGATGCCATAAGTCGTTTCCTGATCGATACACATACAAAGTACATTCAAAGACCCATGACGGTGAGAAATGTTTCAAATGTGACCTATGCCCATATGCTTCGATATCGCAAAGGCATTTAGATTCGCACCTATTGATTCACACTGATCAAAAACCGTTCAAATGTAATTTTTGCGATTTGTCTTTTAGACAAAAACAACTTCTCCGACGGCATGTAAATCTGTATCATGATAAAACATACGTTCCACCACAGCCACAAGAAAAATCGCACTCTTGCCCGGACTGCAAACGAGCGTTTAGTAGAAAAGGAAATCTAATGAGACACATGGCTACGCACGATCCAGAATCGACAGTTAAGGAAGAAAAGGAACAGTTGAAACTAGGTCGGCTGAATAGAATAGAAGGAGGTGGAGTTGACGATGATACTTTAGAAGTTCTAAGTGAAATTGGTGAGGAcatggaagaagaagaagaatacgAAGTTggggaagaagaagaagaagaagtggaaGAAATTGAGAATTATATATCATCATCTAATTGCGAATTAAATTCATCAATGGGAAAtatcataataaaaaaagaagacgaAAAGGATTTAGTGGCACTGGAAGACATTGACGGCCAGCAATATATGGTAGTTGAAATTGTTCAGAGTGATGATGAAAATGACCTGACgcttgaagaagaaaaacttcaCTCCATAAAACATGAACAGTTTGATGACGAATTTATCATTTCAGagcTTGTAAAGGAAGGAGGAATGGGTGAAACGTCAAAGAGTGCTTCTGGTATGGATGATTGCTTTGGATTTAGTGAATCTGAAGAAATTCTCGACCCATCTATAATAAGCCAAGTGGACGAATCAAGTACAGATTCTTACCGTCAAAATTTGGCACCATCTGGCAACAATGAGTCTACTATTGTCATAACGATCGAGACGGATGAAAGAACTCCTCTTTTGGGGGGCTCTAAGAAAAATGGCACGAAAAGACAGAAAAACTCTAAGAATTACTGCGATTTTCTAGCTCTTGGCATAGTTTTAATGTTAGTTGGTGGGTTATCGATTGCAACCTACCTCCTAGTTGTGGAATCTCGTTCACCGACGGTGAGTTTCTCATTGGATCTGGTGGACCGCGGTGTGTGGACTGAGGCAGTTATACCTTTGGGGAGATCGATTGACGATTTCGAAATCTTACATGTTCTTTTGATGCAGACAGGGGGTGAAACTTGTACGGAACTTTATGATTGCATAGATATTCTGAGAGATATGCAGaGTGATACAAACACCGAAATCCCCTTCAATTTTCTGATCGGTGGAGATGGCCAAACCTATGAAGCAAGGGGATGGAATCATGAGAGCGGAATTAATATCTTACCACAACAGTCGTCGTTGGTAATTGGATTCATGGGCAACTACACCTCTTTGCCACCGACCGAGGTACAGTGCACCAGCGCCCTGTCGGTTATACATGAATCTTTGCAGAGGAAGAAACTGAATAGCTCCTACAAAGTTTTCGGCCTCAGGAATCTGTCGATCTCTTCTTATGACGGCGAAGCGCTGTTTGATCGTATTTCAAAGTGGCAGCGATTTGTAACTTTATTGAATGTTGTGTAG
Protein Sequence
MSRLTTDMQIKMESNDLQTYLDTFNKEIEEGNRSLSASLVDAADLMSSNSKDGDEDGGTYFIDQAGNYYYQATKDSDPIPTDPPENVQIVDDESEGEEIEFSKTIVKNRKSYSKNKKSRGDDDSINYVYALDDNEGEVDEEGNEIEEEHDINDQENEEDNEMEDSDDDKVFEFDENEETSSKKSDFVEPKVVMLKPKNGTGITHQCPHCEYVSSKRYLLARHLKCHSDERPYKCPVCERGFKTNASLQNHANTHTGNKPHRCKFCVSTFTTSGELVRHVRYKHTHEKPHKCFECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYECDICHSKFTQSNSLKQHKLIHSVGDKPVFQCHLCPTTCGRKTDLRIHIQKLHTSERPLTCRRCHKSFPDRYTYKVHSKTHDGEKCFKCDLCPYASISQRHLDSHLLIHTDQKPFKCNFCDLSFRQKQLLRRHVNLYHDKTYVPPQPQEKSHSCPDCKRAFSRKGNLMRHMATHDPESTVKEEKEQLKLGRLNRIEGGGVDDDTLEVLSEIGEDMEEEEEYEVGEEEEEEVEEIENYISSSNCELNSSMGNIIIKKEDEKDLVALEDIDGQQYMVVEIVQSDDENDLTLEEEKLHSIKHEQFDDEFIISELVKEGGMGETSKSASGMDDCFGFSESEEILDPSIISQVDESSTDSYRQNLAPSGNNESTIVITIETDERTPLLGGSKKNGTKRQKNSKNYCDFLALGIVLMLVGGLSIATYLLVVESRSPTVSFSLDLVDRGVWTEAVIPLGRSIDDFEILHVLLMQTGGETCTELYDCIDILRDMQSDTNTEIPFNFLIGGDGQTYEARGWNHESGINILPQQSSLVIGFMGNYTSLPPTEVQCTSALSVIHESLQRKKLNSSYKVFGLRNLSISSYDGEALFDRISKWQRFVTLLNVV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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