Msca022249.1
Basic Information
- Insect
- Melanostoma scalare
- Gene Symbol
- Zfa
- Assembly
- GCA_949752695.1
- Location
- OX456985.1:27060791-27069974[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.00015 0.037 16.3 1.1 2 23 230 252 229 252 0.92 2 20 0.0014 0.36 13.3 1.2 5 23 262 281 260 281 0.92 3 20 1.3 3.4e+02 3.9 0.5 3 23 348 368 347 368 0.95 4 20 0.00062 0.16 14.3 0.6 3 23 375 396 373 396 0.88 5 20 1.7e-05 0.0045 19.2 1.0 2 23 404 426 404 426 0.92 6 20 1.9e-05 0.0048 19.1 2.3 1 23 432 454 432 454 0.98 7 20 3.1e-06 0.00079 21.6 1.3 2 23 461 482 460 482 0.97 8 20 0.0014 0.37 13.2 3.6 1 23 488 510 488 510 0.98 9 20 2.6 6.8e+02 2.9 0.5 1 12 515 526 515 529 0.83 10 20 0.00092 0.24 13.8 0.1 2 23 651 673 650 673 0.91 11 20 0.053 14 8.3 0.6 5 23 683 702 681 702 0.89 12 20 0.097 25 7.4 0.4 3 23 707 727 706 727 0.96 13 20 6.8e-05 0.018 17.4 3.2 1 23 739 761 739 761 0.99 14 20 0.014 3.6 10.1 1.5 1 23 767 790 767 790 0.98 15 20 0.056 14 8.2 1.8 2 23 801 822 801 822 0.98 16 20 2.3 5.9e+02 3.1 0.2 1 21 832 852 832 855 0.85 17 20 7.3e-05 0.019 17.3 2.8 2 23 863 884 863 884 0.98 18 20 0.00041 0.11 14.9 3.6 1 23 890 912 890 912 0.97 19 20 0.00037 0.095 15.1 0.6 2 23 918 939 917 939 0.97 20 20 0.00085 0.22 13.9 4.2 1 23 945 967 945 968 0.96
Sequence Information
- Coding Sequence
- ATGGAACTATCAATATATTGCCGTGTTTGTATGGATTCTACTTTTCTGGAATACATTGATCTGGATACTCCATTAAATGATGTAACTTATTTAGAATGCTTCAATTACTGCACTAAGCTGGATGTTGTACTTCAAGACGGACTGCCCAAAACAATTTGCTTATCTTGTggcaaatcattaaaaatagCATACGAATTCATAAGAAATGCACAAGAAACCGATAGTTTTCTACGTGACAACGTTGTTCTTACCGAAGATGATACTAAGCCACAGAATGAAGTTAagaatgaattaatttgttTCGTTAAACCAAATGATGAGGAAGCAATATTTACCAGAGAAATAAGTTCTGCTGATGTAGTTGAAAATAAATACAGTGATAATGTTTATCATAATGTTACACCCATTTGTGTTTTCGATGGAGAAGCGACCCAAAAACAGAACTTTAACAATGATATAAACACAAAAGATTCGGACGATGTGGCTGTTCTTAACATAAGCCAAAACGATTTGAATGATGTTATTgttaaacaaaatgaaaacattgctTTAGAGTCTAAAAGTTCTGATCGAGCAGTTGTTGAGAGTAAACGGGAATACACAACTTTGAAACcctcaaaatgcaaaaaatgtgttcgttgttatttaaaaacacaagaaaacttTAACGACTGTAAAGACCTATGCGTTTGCAACTTATGTGGAGAGGTATTTGAAGATAAAGAACATCTAACCCTTCATGAAAACCTGGATCATAATGACAATGCTGTAGGTTTATGTATCACATGTGGTAAATCATTTTCTGACAAAATATGTTTGCAAAAACATGTCGCAAAAGAACACGGATTTCAAGTTCAACTAGTAAATAACATTGGAAAGCACAAAACGTCTGGTTCTTTGCCTTTGGCGGTAGAAAACTACACAAATCCAAAACTATTCCAACGTAACtcacccaaaaaaaaacaaaacatttccttcaAGGATTTAAGTTATATTAAgtcaaaaaatgctttgaacGACGAAATGCTTAAAGAAAGGTTGTGTAACAGATGCGACTTTAGTACAAGGGATGCACTTTTATGGATAAGACACAATAAACTTCATCGtcaaaaaaaacatctttgcgcATATTGCCCACGAAGTTTTAGCAcaacatcatccctcagtgcgCACGAAGACTACGCACATggtgataaaaaaaatgcaCCCCAATGCAAAATATGTGATAAGAAATTCATTAGTAAGTATTTGCTGAAAAGACACAATGCAAGTGCTCACTCAGAAGAACGACCGTTTGAATGCAAACAATGTCCAAAAACATTTAAGTTTATCTCGAATTTGACAATGCATGAAAAAAGGCATAATCCAGGCAAGAAAATCGAATGCCCACATTGTGATAAAACGTTTGTAATGAAAACCGATATGAGAGTTCATCTGAGAACACATACTGGTGAAATGCCATATGAGTGTCATTTGTGTGGTCAAAAGTTTCGAATTAAAGTGAGGTTAACTTATCATTTGAAGAGACACGAAGGGTATCCGTATGCTTGTGAGATTTGCAACAAGGGGTACGGCAAGAAAACGAAGTCATTAAAAATAGCATACGAATTTGTTAAATCCGCTCATGAAGCTGACAATTTTCTTCGTGAAAACTTTATCCTTACTAGAGATAGTGCAAAGCACCTTGATGGAATTAAACACGAGCACCCTTATTTTGTTGAATCCTTGAAAGAAGAAGTGGATATTGATCAACAACTTAAAGAAGAAACAGTTCGTTATGAAGGCGAACATAAGGCAATTCAGCCCAGATTTGAAATTATATTTGAGGCAGAAGTTCCAAAAGACAGAATTGAGGACAATGATTTGAATTTATCCTTGAACGAAAAAGACATTCTTTCTGTGGATGGTTTAACCATTCGCAAAGCACAAACTAATAAAACAGGTTCACAAGTTTGCCGTTTGTGTGGAGAAgtatttgaaaatagaataaatCTGAATCAACATAAGCTTGCTGAACACAGAGGAAAACACGTAGGCTTGTGTATCACATGTGGTCAATCGTTTCCCGacgaaaattgtttaaaaaaacacacagcTCTAGAACACTTTCCGAGTGCATGTCAATACTGCAAAAAAAAGATCAGTATTATCGGCCTTAAAAGACACATAAGGACCGTGCATGGTGATGTATTGCCAACTGCAGAAAAAAACGAATTTACTTGTGAATACTGTTCAAAGTTTTTCTCCAGCGATAAGAAACTAAAAGACCACCTGAACACACATACAGGCAAACGACCTTACGTATGTGAAGCTTGTGGAAGTAGTTACCATACAGAATGGAACCTTAGGTATCACAAAAAAACAATGCATGATACGCAATATGAGTATGCCGAACCTCGAAAGTGTCAAAAATGCGACTTTAGCACAACAAACAGATTGTTATGGATTAAACATGGAAGACGTCATGATAAACCAAAGCAGAACATACAAAAATACCTGTGCGCATCTTGTCCAAAGAAATTCCTCTTTCCAAAATTGCTTGAACAGCACGAAATTTTCGCACATGGTGATAAAAACGTTGGACCTCAATGTAAAGTTTGTAATAAAATTTACAGAAACTATGATTGTCTGAAAAGTCATATGATGGTTCATTCAGAAGAGCGACCGTTTGAGTGCAAAGAATGTCCGAAAACTTTTAAGTACATGACTTCGCTACATACTCATGAAAAACTACACAAGGGAAAGCAAGTGGAATGCCCTCATTGTGATAAGAAGGTGTTATCACCGCGTGACTTGAAAATACATCTCAGGACGCATACAGGGGAACGGCCATTTGAGTGTCATTTGTGCGATCGAAAGTTTGCCGTTAAAGTTAGGCTGACTGATCACTTAAAGAGACATCATGTGGGCGTGTTGCACAAGTGA
- Protein Sequence
- MELSIYCRVCMDSTFLEYIDLDTPLNDVTYLECFNYCTKLDVVLQDGLPKTICLSCGKSLKIAYEFIRNAQETDSFLRDNVVLTEDDTKPQNEVKNELICFVKPNDEEAIFTREISSADVVENKYSDNVYHNVTPICVFDGEATQKQNFNNDINTKDSDDVAVLNISQNDLNDVIVKQNENIALESKSSDRAVVESKREYTTLKPSKCKKCVRCYLKTQENFNDCKDLCVCNLCGEVFEDKEHLTLHENLDHNDNAVGLCITCGKSFSDKICLQKHVAKEHGFQVQLVNNIGKHKTSGSLPLAVENYTNPKLFQRNSPKKKQNISFKDLSYIKSKNALNDEMLKERLCNRCDFSTRDALLWIRHNKLHRQKKHLCAYCPRSFSTTSSLSAHEDYAHGDKKNAPQCKICDKKFISKYLLKRHNASAHSEERPFECKQCPKTFKFISNLTMHEKRHNPGKKIECPHCDKTFVMKTDMRVHLRTHTGEMPYECHLCGQKFRIKVRLTYHLKRHEGYPYACEICNKGYGKKTKSLKIAYEFVKSAHEADNFLRENFILTRDSAKHLDGIKHEHPYFVESLKEEVDIDQQLKEETVRYEGEHKAIQPRFEIIFEAEVPKDRIEDNDLNLSLNEKDILSVDGLTIRKAQTNKTGSQVCRLCGEVFENRINLNQHKLAEHRGKHVGLCITCGQSFPDENCLKKHTALEHFPSACQYCKKKISIIGLKRHIRTVHGDVLPTAEKNEFTCEYCSKFFSSDKKLKDHLNTHTGKRPYVCEACGSSYHTEWNLRYHKKTMHDTQYEYAEPRKCQKCDFSTTNRLLWIKHGRRHDKPKQNIQKYLCASCPKKFLFPKLLEQHEIFAHGDKNVGPQCKVCNKIYRNYDCLKSHMMVHSEERPFECKECPKTFKYMTSLHTHEKLHKGKQVECPHCDKKVLSPRDLKIHLRTHTGERPFECHLCDRKFAVKVRLTDHLKRHHVGVLHK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -