Msca002161.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melanostoma scalare
Gene Symbol
grau
Assembly
GCA_949752695.1
Location
OX456984.1:25163374-25167767[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.084 22 7.6 2.4 2 23 215 237 214 237 0.87
2 17 0.01 2.7 10.5 1.4 6 23 246 263 246 263 0.99
3 17 1.3e-05 0.0034 19.6 1.6 1 23 269 291 269 291 0.99
4 17 1.7e-06 0.00045 22.4 0.4 1 23 298 320 298 320 0.99
5 17 7.5e-05 0.019 17.2 1.0 2 23 328 350 327 350 0.95
6 17 0.035 9.1 8.8 0.9 2 23 359 381 358 381 0.95
7 17 0.0019 0.5 12.8 0.1 2 23 389 411 389 411 0.94
8 17 0.069 18 7.9 0.1 1 11 417 427 417 433 0.88
9 17 2.9 7.6e+02 2.8 0.3 2 23 624 646 623 646 0.92
10 17 0.038 9.9 8.7 0.1 6 23 655 672 655 672 0.99
11 17 0.0053 1.4 11.4 1.4 1 23 678 700 678 700 0.98
12 17 2.8e-05 0.0073 18.6 1.5 1 23 708 730 708 730 0.99
13 17 2.6e-05 0.0068 18.7 0.3 2 23 737 759 736 759 0.95
14 17 1.2e-06 0.00031 22.9 0.5 3 23 767 787 766 787 0.96
15 17 0.00042 0.11 14.9 0.4 2 23 796 818 795 818 0.95
16 17 0.0011 0.27 13.6 0.1 1 23 825 848 825 848 0.93
17 17 0.0029 0.76 12.2 0.2 1 17 854 870 854 871 0.89

Sequence Information

Coding Sequence
ATGCTTTGCATTTTGTGTGTTTCATCCTCCGAGGAAATAATAGACATTTTTGGCGAAAACGGTATTCAACTAAACATTGACTGCGTCATAACCAAGTATTTTTGGTTGCAgCCAAATGCAAATGAAATCAATGCTAAATATATTTGCTGTACATGTTGGAATAAAGTACATTCATTCCACGAGTTTTACCAATTCGTGGAAGAAGCGCATACTAACCTTAGTACTCTCAAACTTCCACCTGAAGATAATGATCCCGAGACCAATACTTTTGATGCCTACTCTGACTTCTTTGATCCagACATCAAAGTCGAACACTCTGATGATGATCACTCAGAAGCTGATGTTGGTGAACATGCAAGTTCACAGAATGATATGAAAGAACTAATGAATTCAGATGATTCTGAGTTTGATGTTCCTCTTGTAAAGTTGAGTAACCGTGAAAGCAAAAGCGAACAGCTTACTGACAATGAAACTTCCTCCGTGCACGATCAAGAGATGTCTGAATCAGACAACGAAAGTGATTACAAGCCGAcgaagaaaaaaaccaaacagaAAACCGTACTTTCCACAAACAAAGATTCAACTAAGACTGGTGTTTCTTGTAGAGATTTTGATgactttataaaaaaacacaTGCAATTGACATGTCCCATCTGCAAAAAGCCATCGAAGAATTTCTTTAGCCTCAAAGAGCACTGCCAATCCGCACATAAAGAAGTAGCTTATGTAACCTGCTGTGACAAGCAGTTTTCTTCGCGTTTTTCCTTAGTACATCATCTAATGATCCATCAAGATCCTGATTTTTTCAAGTGTGGTCAATGCGGACGAgttttggcaaacaaaaaaagctttaaaaatcaCATGAAAAGCCACAAAAATAGAGAACGCGTTTATAAATGTCCGAAATGTCCAAAAAGCTTTCCAACAGAGCAATGggttgaaaaacatttaaagaCACATAATATTCCCCCTCTTGAACTTATATGTGAACAATGTGGCAAAGTTTGTCGGAGTAGACAAGGCCTGAAAGCGCACCAACTGCGAGAGCATACAGATTTTCGCAAAGAACGTGTGCAATGCAAGATATGCGGTGCATATCTGGCTGATACATCAACTTTACATACTCACACGAAATATCAACATCCAAAAAAAGAAGTATTGAATGTTTGCAATATTTGTGGGAAAATATCAGCTTCCGGCTATGGACTTAAGCGACATATTTTGTATATGCACACTATGGAGAGGCGTCACAAGTGTCATTTGTGTAACAAGGCGTTCAAACTCGCCCAAGTACTCCGGATTGCTGAACACGACGTTTGGTCGTGTTGTGATGCAATTGATTTTACTACTGATGACGTTAAAAGGTACGTTTCAATTTCCACAGACATCAAATTGGAAGTTAAGGAGGATGCAGAAGTTTCTTTGGCCACAAACGTTTCCGTATGCGAAAATAATGAAAGCAAATTGGAACCTCAAACAGAGTCCTTGTATGAGTGCAAAGAAGCTCCAGCCGTTAGATCTACCAGAAGTCGTAAGTCAACAGAAATGGCTTACGCAGAGAGTGAGTCTTCGAGTGACGATGAAATAGACTCTGACCATGCGGAAACTAGAAGATCCAATTCTTCGTTAAACTGGCAAGAAGATGAAAACTCTGACAACGTCGATGATGACAGTGACTATGAAGATAACAGAGTTCCGACATCAAATAAATGTGACGAACCAtcaaaagaaattaagaaaCGTGGTCGTCCGAGAAAAGTTGGAACCAGATCGTCACCGCATAAGAAAAAACGATTCTCTCAGGAGCAGTCCACAAAAATGCAGCGCATTCAAGAGTACGATGAAACGATTGCAAAGAACATGAAACTCTCGTGTGCCGTGTGTCTTgaagtatttttaaattttgctgttCTCAAAAGACATTTTCGTTCAAAACACAACGAGTGTGGCTATGTGGCTTGCTGCGGCAAAAAGTTTCGCAAGCGTGGCGTTCTGGTTGATCACATTTACACCCATCAAAATCCCGAGTACTTTAAATGCGATAAATGCGGGCGAGTTCTGGCAAATCGAAAGGGACTAGACTGTCATATGCTAACTCATGATACTGAAAAGCAACGCATATACCAATGCGACCAGTGCACACTGAGTTTCTTTACCAGACCGCTACTAACACGTCATTTACAAACGCACATTTCTGAACGCAATATCAAGTGTCCAGAATGTGACAAGTTCTTCTCAACACAAGACATCCTCCGCACGCATATCAACAACGTACACAATGCAGCTTACACCAGAATTTGCGATCAATGCGGGAAGTCGTTTCGCAGACCAGATGCATTTCGTCGCCATCAGCTGGAGCACGATGGTATAACTCAACCTATGGTTCCTTGTGAAAAATGCAATGTAAAGTTGACTAGCAAGTATGGCCTTAAGAGGCACATGGAGTCAATGCATCCGGAAACAGATGTCAAGCATGTGTGTAATGAATGTGGAAAGATTGCGCCAAGTGCAGCTGCTTTGCAGCGACATGTCTCGTATATGCACAAAATGGAACGTAAATACAAATGTCCCATGTGCGATAAGGCTTTCAAGAAAACTGGCGGACTTAAGGTCTTGTGTAAAATGAATAGGGTCTCGTTTATAGTTGATTGTTTTCTTAACCGTTTAGGTGAACTCACTGTAGACGAAGTCCTTTACTTATGTTAA
Protein Sequence
MLCILCVSSSEEIIDIFGENGIQLNIDCVITKYFWLQPNANEINAKYICCTCWNKVHSFHEFYQFVEEAHTNLSTLKLPPEDNDPETNTFDAYSDFFDPDIKVEHSDDDHSEADVGEHASSQNDMKELMNSDDSEFDVPLVKLSNRESKSEQLTDNETSSVHDQEMSESDNESDYKPTKKKTKQKTVLSTNKDSTKTGVSCRDFDDFIKKHMQLTCPICKKPSKNFFSLKEHCQSAHKEVAYVTCCDKQFSSRFSLVHHLMIHQDPDFFKCGQCGRVLANKKSFKNHMKSHKNRERVYKCPKCPKSFPTEQWVEKHLKTHNIPPLELICEQCGKVCRSRQGLKAHQLREHTDFRKERVQCKICGAYLADTSTLHTHTKYQHPKKEVLNVCNICGKISASGYGLKRHILYMHTMERRHKCHLCNKAFKLAQVLRIAEHDVWSCCDAIDFTTDDVKRYVSISTDIKLEVKEDAEVSLATNVSVCENNESKLEPQTESLYECKEAPAVRSTRSRKSTEMAYAESESSSDDEIDSDHAETRRSNSSLNWQEDENSDNVDDDSDYEDNRVPTSNKCDEPSKEIKKRGRPRKVGTRSSPHKKKRFSQEQSTKMQRIQEYDETIAKNMKLSCAVCLEVFLNFAVLKRHFRSKHNECGYVACCGKKFRKRGVLVDHIYTHQNPEYFKCDKCGRVLANRKGLDCHMLTHDTEKQRIYQCDQCTLSFFTRPLLTRHLQTHISERNIKCPECDKFFSTQDILRTHINNVHNAAYTRICDQCGKSFRRPDAFRRHQLEHDGITQPMVPCEKCNVKLTSKYGLKRHMESMHPETDVKHVCNECGKIAPSAAALQRHVSYMHKMERKYKCPMCDKAFKKTGGLKVLCKMNRVSFIVDCFLNRLGELTVDEVLYLC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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