Basic Information

Insect: Melanostoma scalare
Gene Symbol: Bcl11b
Assembly: GCA_949752695.1
Location: OX456986.1:165356228-165366318[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3.7e-06 0.00094 21.4 1.1 1 23 126 148 126 148 0.97

2 13 3 7.7e+02 2.8 0.2 3 23 165 184 164 184 0.76

3 13 0.0053 1.4 11.4 2.0 3 21 192 210 190 212 0.95

4 13 1.4e-06 0.00035 22.7 0.3 1 23 218 240 218 240 0.96

5 13 6.8e-07 0.00017 23.7 0.9 1 23 246 268 246 268 0.99

6 13 0.00081 0.21 14.0 0.1 1 21 274 294 274 298 0.92

7 13 2.6e-05 0.0068 18.7 3.9 1 23 382 404 382 405 0.96

8 13 3.1e-07 8.1e-05 24.7 6.6 1 23 410 432 410 432 0.99

9 13 0.00011 0.028 16.7 0.3 3 23 449 468 448 468 0.98

10 13 2.5e-06 0.00063 21.9 1.3 1 23 474 496 474 496 0.99

11 13 1.2e-07 3.1e-05 26.1 0.2 1 23 502 524 502 524 0.98

12 13 1.4e-07 3.5e-05 25.9 0.6 1 23 530 552 530 552 0.99

13 13 0.002 0.53 12.7 0.8 1 23 558 582 558 582 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3.7e-06	0.00094	21.4	1.1	1	23	126	148	126	148	0.97
2	13	3	7.7e+02	2.8	0.2	3	23	165	184	164	184	0.76
3	13	0.0053	1.4	11.4	2.0	3	21	192	210	190	212	0.95
4	13	1.4e-06	0.00035	22.7	0.3	1	23	218	240	218	240	0.96
5	13	6.8e-07	0.00017	23.7	0.9	1	23	246	268	246	268	0.99
6	13	0.00081	0.21	14.0	0.1	1	21	274	294	274	298	0.92
7	13	2.6e-05	0.0068	18.7	3.9	1	23	382	404	382	405	0.96
8	13	3.1e-07	8.1e-05	24.7	6.6	1	23	410	432	410	432	0.99
9	13	0.00011	0.028	16.7	0.3	3	23	449	468	448	468	0.98
10	13	2.5e-06	0.00063	21.9	1.3	1	23	474	496	474	496	0.99
11	13	1.2e-07	3.1e-05	26.1	0.2	1	23	502	524	502	524	0.98
12	13	1.4e-07	3.5e-05	25.9	0.6	1	23	530	552	530	552	0.99
13	13	0.002	0.53	12.7	0.8	1	23	558	582	558	582	0.92

Sequence Information

Coding Sequence: ATGGAAGAAGCAATTCTGAAGGAAAAATTATACAGTAATAATGAAGATGAAGATACCCAGCATGTCCAAGGACCATCATTATCTGTTAGACTTGGAATCGTATGCACAAACGACAACGAGTTTGATGACAGTGCTTCTATAAAATCGGATTTCTCCCTACTACCACGAATCAACGAGGTACACGAGATAAAGAGTGAGAGTGACGCAGATGATGGGCCAAGTAAAAAAACTCGAAAAGTCGAAGGAACTGAAAAATCTTCTCACCACAGTGACGCAGATGAAGTGCCAAGAAGAAAAACTAGTAAACTAGATCGAGATGAAAAAAGTTCTCACCAGAATGATGAAGATAATCACGCGAAATCAGATTCCGAGGCATTCGCCTGCAAACAATGTAACCGAACATATGCACGCGAACGAAATCTTCTTAAGCATATGCAAGTACACAAAGACCTTGCAACTGGGGTTAGAAAACCTCCGGAAAAATTTGGCATTTGTCCTTTCTGTGGTGATAATTTTCCCCAAAAGAGTCTGCCCGTGCATATCAAAAGACACACTGGTGAAAAGCCATACGGATGTGATCAGTGTGATATGCGTTATGTTCGGCGTCAAGATCTTAAAGTTCACCAGCGCTGCCATTCTGGGGAGAAACCTCATATATGTCTGACTTGTGGAAAGGCTTTTCCACGAGCCAATCAACTTGTCCGGCACATCAGAGTGCACACGGGTGAACGTCCTTATAAGTGTAATCAATGTGATAGAGGTTTTGCTCAAAGAAACGATTTAAATTTACACATACGTCGTCATACGGGTGAAAAACCATACAAATGTGGTGTATGCGGACAAGGATTTATCAATGGGACACTGTTAAGAAATCACCGCAAAGCTGTTTCTCATTACGAAGAAGAACGTCGGGATCGTTTTGAGAAAATTCCTGTTCCTAATCAATATGGATCGTTCAATGATGGGGAAATCTCCGATGACTTATCGATTAAATCAAACCCAGCCACGCCAGCAGCAATAAACGACGAAAATCTTGAAGAAACTTTGAGTGAGACTAGTTTGAAGATAGATAAGAAAtctaaaaaacctaaaaaacttaaaacaaaaaaccgaaAAGAACAACACGACTCTAAAAGACCAACCTTTGAATGCACCGTATGCGATCAAACTTTTGATAGACGTGAATCATTTTTACGTCACAAAAGATCACATCACACTCCGGGTACCTTTCAATGTAATCATTGCGACAAACATTTTGTACGAAAGAGAAACCTCCTGCGGCATATGAAAATCCACAAAGGAACAGGAAATGTTTCAATAGAACCCCAAAGCAAACACGAACTATGTCCGTTCTGTGGTAAAAGTTATTCCCAAACTAGTCTAGCAATTCACATAAGGCGACACACTGGTGAAAAACCTTATAAGTGCGACATTTGCGATAAGGGATATCCTCGTTCGCATGATCTCATGATACATAAACGCTCACATACTGGTGAGAGACCACACGTTTGTCCAACTTGTGGTAAGGCCTTCATTCGGCCGAATAAACTAGCGCGACACATTCGGGTACATACCGGCGAACGTCCTTACAAGTGTACACAATGTGGCAAGGGGTTTGCGCAATCGAACGATTTAAATTTGCATATTCGTCGACACACAGGTGAGAAACCTTACAAGTGCGGCGTCTGCCAGCAAGCATTTATCAATGGAACTGCACTCAGAAATCATCACAAGTCAACAGACCATTATAGCATAAAGGATCAGTGTCCAGATCGTTTTGAGAAAATTCGTGTTGATAATCCGTATCGGCAATCATATCAAACATGTTGGAGAACAAAAACCCTTAACACCAAACAGGATATTGAGGTAGTAAAAGCTTGCAGCGACGAAAATAATGGAGAGCAAGGGGCAGAAGATCTAAGTATATACAAATTAAGTACTGATTGGACAGCACACAACTAA
Protein Sequence: MEEAILKEKLYSNNEDEDTQHVQGPSLSVRLGIVCTNDNEFDDSASIKSDFSLLPRINEVHEIKSESDADDGPSKKTRKVEGTEKSSHHSDADEVPRRKTSKLDRDEKSSHQNDEDNHAKSDSEAFACKQCNRTYARERNLLKHMQVHKDLATGVRKPPEKFGICPFCGDNFPQKSLPVHIKRHTGEKPYGCDQCDMRYVRRQDLKVHQRCHSGEKPHICLTCGKAFPRANQLVRHIRVHTGERPYKCNQCDRGFAQRNDLNLHIRRHTGEKPYKCGVCGQGFINGTLLRNHRKAVSHYEEERRDRFEKIPVPNQYGSFNDGEISDDLSIKSNPATPAAINDENLEETLSETSLKIDKKSKKPKKLKTKNRKEQHDSKRPTFECTVCDQTFDRRESFLRHKRSHHTPGTFQCNHCDKHFVRKRNLLRHMKIHKGTGNVSIEPQSKHELCPFCGKSYSQTSLAIHIRRHTGEKPYKCDICDKGYPRSHDLMIHKRSHTGERPHVCPTCGKAFIRPNKLARHIRVHTGERPYKCTQCGKGFAQSNDLNLHIRRHTGEKPYKCGVCQQAFINGTALRNHHKSTDHYSIKDQCPDRFEKIRVDNPYRQSYQTCWRTKTLNTKQDIEVVKACSDENNGEQGAEDLSIYKLSTDWTAHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -