Mror030170.2
Basic Information
- Insect
- Melanophora roralis
- Gene Symbol
- grau
- Assembly
- GCA_963583895.1
- Location
- OY757191.1:72396919-72399045[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.23 25 6.6 0.7 2 23 291 313 290 313 0.92 2 10 2.1 2.3e+02 3.6 1.6 6 23 322 339 322 339 0.97 3 10 0.00035 0.038 15.5 1.1 1 23 345 367 345 367 0.97 4 10 0.0012 0.13 13.8 1.8 1 23 375 397 375 397 0.96 5 10 1.8e-05 0.0019 19.5 2.1 1 23 405 428 405 428 0.98 6 10 0.11 12 7.6 1.1 3 23 436 456 435 456 0.96 7 10 0.0012 0.13 13.8 0.2 2 23 465 487 464 487 0.93 8 10 0.57 62 5.4 2.0 1 23 495 518 495 518 0.90 9 10 1.4e-06 0.00015 23.0 1.7 1 23 524 546 524 546 0.98 10 10 5.2e-06 0.00056 21.2 1.8 1 23 552 575 552 575 0.98
Sequence Information
- Coding Sequence
- ATGGAAAGTTGTTTACTGTGTCTAAAACCAAAAAAGGCATATGAGCAGACTATAAATATGCATTTCAAAGAATGGAACGAATTAAGTGTTAAACagttaataaagaaatatttgtggTCAATGaacCATTTAGAGGATACTTCTTGGTTATGCAGCGTATGCTGGAGGGCATTGTTCGAATTCCATACATTTTTTACGCGCATTGAAAAGGCTCATATCGGTTTTGGTTTAATTATCCCAAAAATAGTATATGAAAACAAAGGCACCCCGTCCTTTCATGAAGGGGCTTCAGTAGTAACGGAAGATAAGAAAAGCCCTTCTGACATATCAATAGATTGCGCAGAcgataaattacaaaattttttaaatgaaaatgtctCTAATGATAATTTAGAAAatgaacaacaacaaatttcgCTAAAACCTTCGGCTaaaagtgaaaacaaaaaaaatactaacaatGAAATAGTCCTCCAGCAAAAACGAAAGCGTGGGCGACCgcgaaaaaatataaagaatgaCCTTAAAACACTAATTAAAGATCGTTGTAATAactcaattaatattttaacgcataaaaataaaaaacaaagaaatcgaAGCAAATTAGATGAGACACTTTTTAAAAACGGggaacataataaaaatactctTTCAATTCAAATTTCTCCTTtggaaataaaacaagaaaccTTTTCTTTACATTTGAAGAATGACCCCGATACTTCAATTGATAGCAATGTCAACGATTCAGATTCCAATAATGAGGACAACGGTAACCACAGCCTGGAGCATTTTGAAAGAAAACCGGTTGTACCCAAAACTATTCGTAATGAACGTGATAAGTTTTTatcggaaaattttaaaatcacctgCTTTTTGTGCAATATaccttttgaaacattttttgccaTGCGTAAACATTTCAACGAAAACCATACGGAACGTGGACATGTTAAgtgttgcaataaaaaattttatagacgTAGTATTTTAGTCGatcatgtacatcgccatttAGACCCAAATTACTTTAAATGTAATCAATGTGATAAAGTATTGGCAGATAGACGTTGCCTGGAATTACATATTGAAAATCACGAAGGTAATCAAGAAAAAAGCCATTGCTGTGACATTTGTGGAAAAGGATTTGCAAAAATTGGCGTattaaagaaacataaaatgatACATTTGTCGGAAGGCGAAAAACAATTTCGCTGTTTAGAATGTGGTAAAAACTTCGGCTCTAACTATTTACTAACCAGTCATCATCGCTCAGTACATCTTAAAAAGTATGCCAAAATCTGTGACATCTGCGGTAGATCTATACGTTGCAAAGATGTTTTTGAACGGCATATGCTACAGCATGAAGGAAAAATTGCTCCCACCATTAGTTGCGACGTATGTGGCCTACGCTTGACAGACAATAAAGCTCTAAAGCGTCACAAAGATATGATACATCCAATTGGTGGAAAACAGGAATACACTTGTTCAATATGTTCCAAAATTTCTCCTAATCTTAAGGCTCATAAGAGACATGTTCAATATAAGCACATAATGGGATACGATCACAAGTGTACAATATGTGATAAAGGTTTTAAAAGAGCTCAAACATTAAGGgaaCACATGGCTTCGCACACAGGCAGTATATTATACACTTGTCCTTGGTGTCCGAAAACATTTAATTCCAACGCCAACATGCATAATCATCGCAAAAGGGTGCACCCCAAAGAGTGGGAGGAAACAACTCGTGAAAGATATTCTGGCAAATTACCACCCAATTTCAAACCACCAATTAAAATAGAGAATACAGACTTAAGCTTGTCTATGGATTAG
- Protein Sequence
- MESCLLCLKPKKAYEQTINMHFKEWNELSVKQLIKKYLWSMNHLEDTSWLCSVCWRALFEFHTFFTRIEKAHIGFGLIIPKIVYENKGTPSFHEGASVVTEDKKSPSDISIDCADDKLQNFLNENVSNDNLENEQQQISLKPSAKSENKKNTNNEIVLQQKRKRGRPRKNIKNDLKTLIKDRCNNSINILTHKNKKQRNRSKLDETLFKNGEHNKNTLSIQISPLEIKQETFSLHLKNDPDTSIDSNVNDSDSNNEDNGNHSLEHFERKPVVPKTIRNERDKFLSENFKITCFLCNIPFETFFAMRKHFNENHTERGHVKCCNKKFYRRSILVDHVHRHLDPNYFKCNQCDKVLADRRCLELHIENHEGNQEKSHCCDICGKGFAKIGVLKKHKMIHLSEGEKQFRCLECGKNFGSNYLLTSHHRSVHLKKYAKICDICGRSIRCKDVFERHMLQHEGKIAPTISCDVCGLRLTDNKALKRHKDMIHPIGGKQEYTCSICSKISPNLKAHKRHVQYKHIMGYDHKCTICDKGFKRAQTLREHMASHTGSILYTCPWCPKTFNSNANMHNHRKRVHPKEWEETTRERYSGKLPPNFKPPIKIENTDLSLSMD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -