Basic Information

Insect: Melanophora roralis
Gene Symbol: topi
Assembly: GCA_963583895.1
Location: OY757187.1:113380029-113381833[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2e-05 0.0022 19.4 0.4 2 23 230 252 229 252 0.96

2 10 0.00017 0.018 16.5 1.1 2 23 260 282 259 282 0.95

3 10 0.0012 0.13 13.8 0.9 1 23 301 324 301 324 0.92

4 10 0.00043 0.047 15.2 1.0 2 23 345 367 345 367 0.96

5 10 2e-05 0.0022 19.4 1.4 3 23 376 397 374 397 0.96

6 10 0.014 1.5 10.4 3.9 1 23 417 439 417 440 0.95

7 10 5.8e-05 0.0063 17.9 1.6 1 23 446 468 446 468 0.98

8 10 7.7e-06 0.00083 20.7 0.1 1 23 474 496 474 496 0.99

9 10 2.7e-09 2.9e-07 31.6 3.2 1 23 502 524 502 524 0.99

10 10 0.00077 0.084 14.4 1.0 2 21 531 550 530 554 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2e-05	0.0022	19.4	0.4	2	23	230	252	229	252	0.96
2	10	0.00017	0.018	16.5	1.1	2	23	260	282	259	282	0.95
3	10	0.0012	0.13	13.8	0.9	1	23	301	324	301	324	0.92
4	10	0.00043	0.047	15.2	1.0	2	23	345	367	345	367	0.96
5	10	2e-05	0.0022	19.4	1.4	3	23	376	397	374	397	0.96
6	10	0.014	1.5	10.4	3.9	1	23	417	439	417	440	0.95
7	10	5.8e-05	0.0063	17.9	1.6	1	23	446	468	446	468	0.98
8	10	7.7e-06	0.00083	20.7	0.1	1	23	474	496	474	496	0.99
9	10	2.7e-09	2.9e-07	31.6	3.2	1	23	502	524	502	524	0.99
10	10	0.00077	0.084	14.4	1.0	2	21	531	550	530	554	0.88

Sequence Information

Coding Sequence: atgacaaaaattagtcaatacaaaaataaatgccGGACATGTTTAAATGGTATAAAGGGCTTACaacagctaacaaaaattataaacttagaTAAAGAGGAAACAAAATCTTATGCTGAATTGTTAAAAGATTTAACCCAAATTGatATAATGGACGAAACATTTCATGAGATGCCTCAAGTGATATGTGTCTGCTGCATACGTAAATTGAAAGCTGCCTATGCTTTTGTACGACAGACCCATGAAGTCAACGACCACTTGTTGTCAATACTCAATAATGAAGATAAACCTATTAATTGTTTCCAAGAAGCTCAAATAGATATTCAGGATTGTTTCGAAATGAAAATTGAAACTGGACAAAGTGAAAAGCAGCAAGCGCAAACAATATTTAGTGCAAAAGGGACACAAGAAAATCCGAAAAAAGACAGTATTGAGAAAATTACGTCTACAGATGAATTTACTGGCGCAAGAGTGGAAAACAAAGTAAATGTTATTGAAAATGATGGCCTCGAGACAAAAGCTCTGTCTGAATGTAAAGATgactttgataaaaattttgttactgtCAAGACATTAGAAACCAACTCTCCTCAACATAATGTTAATACATCTGAAAACGAAAGTGATTTAGAAATTTCGATTAATACTCAAAGCAActcaaaaaatgataaaaatgccAAAAGTATAAGTTGCAAACAATGCAATCAAGTTTTTTCCGATGACAGTCAACTTAAAGTCCATAAACGTGTTGCACACATTTCTGAACAAAACAAAACACCGTGTCCATTTTGTTCTCGCGAATTTAATCGACGTTATTTAATGTATAGACACATGCGGGCGCGTCACAAAGATAAGCCCATAGAAGAGCACATTCCGCAACAAAGAAAACTACCTCGGCAATATGCGTGCGAAATATGTGAATGCAGCTATACTACCATATTCAACTTACGAGCCCATTTGACAGCAAAGCACAATTTTGAAGATCAtggacaaaaaaaaagacaaattcaAGCAGAGAAATCTTTAGCTAGACGCTGTGACGAATGCGGCactatttgtaaaaactatAGCGCTCTATATGCTCATCAGAAGCAAGTTCATATTAGCGAAGATAAGTGTAGTTTTTGCCCGCATtgtggtaaaaaatataaaaagaagataGATCTGCGGATTCATATCGAAAGAGCTCATAATGGCAAAGAACTAAATGACGATGCCAAACAACCGGTGAAAGCAAGGGAAAAGCGTTTTATGTGTACGCAATGCTCTTACATCTGTACTACAATAAGCGTTTTAAATGTTCACATTAAACGCCATCATACCGGTGAAAAACCCTACAAATGTGATATATGCTCCAAATCGTTTTATGTagcttttgatttaaaaattcatcGCTATAAGCATACAGGCGAAAAGCCCTACCAATGCCCGATTTGTTCGATGGGTTTCCGAGACAACGCCACAATGATAACACACCAGCGTGTGCATAGCAATGAAAGGCCCTATAAGTGTGATGAGTGTGGGAAAAGTTTTAAGCACAACAGCAATTTATCGACTCACATGCGAATTCAtctaaaagaaaagaaactaaATTGTGTACTATGTGGTAAAGTGTTTGAAAATAGATCGTGTTTAAATCTTCATCGTATTAATGAAAATCACTACGAAGAAGAAAATTGTTGA
Protein Sequence: MTKISQYKNKCRTCLNGIKGLQQLTKIINLDKEETKSYAELLKDLTQIDIMDETFHEMPQVICVCCIRKLKAAYAFVRQTHEVNDHLLSILNNEDKPINCFQEAQIDIQDCFEMKIETGQSEKQQAQTIFSAKGTQENPKKDSIEKITSTDEFTGARVENKVNVIENDGLETKALSECKDDFDKNFVTVKTLETNSPQHNVNTSENESDLEISINTQSNSKNDKNAKSISCKQCNQVFSDDSQLKVHKRVAHISEQNKTPCPFCSREFNRRYLMYRHMRARHKDKPIEEHIPQQRKLPRQYACEICECSYTTIFNLRAHLTAKHNFEDHGQKKRQIQAEKSLARRCDECGTICKNYSALYAHQKQVHISEDKCSFCPHCGKKYKKKIDLRIHIERAHNGKELNDDAKQPVKAREKRFMCTQCSYICTTISVLNVHIKRHHTGEKPYKCDICSKSFYVAFDLKIHRYKHTGEKPYQCPICSMGFRDNATMITHQRVHSNERPYKCDECGKSFKHNSNLSTHMRIHLKEKKLNCVLCGKVFENRSCLNLHRINENHYEEENC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00975838;
90% Identity: -
80% Identity: -