Mror025645.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melanophora roralis
Gene Symbol
ZEB2
Assembly
GCA_963583895.1
Location
OY757190.1:92898985-92904341[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 5.6e-05 0.006 18.0 1.1 1 23 189 211 189 211 0.95
2 14 3.2e-06 0.00035 21.9 2.3 1 23 285 307 285 307 0.98
3 14 8e-05 0.0087 17.5 0.2 1 23 419 441 419 441 0.96
4 14 0.059 6.4 8.4 3.5 1 23 447 469 447 469 0.97
5 14 1.8e-06 0.00019 22.7 0.5 1 23 486 508 486 508 0.99
6 14 0.0024 0.26 12.8 0.6 1 23 517 540 517 540 0.95
7 14 0.0028 0.3 12.6 5.2 1 23 546 568 546 568 0.98
8 14 2.7e-05 0.0029 19.0 0.6 2 23 575 596 574 596 0.97
9 14 2.2e-08 2.4e-06 28.7 0.7 1 23 602 624 602 624 0.96
10 14 0.055 5.9 8.6 1.7 1 23 630 652 630 652 0.97
11 14 4.1e-05 0.0045 18.4 2.3 1 23 658 680 658 680 0.96
12 14 1.6e-05 0.0017 19.7 3.5 1 23 686 708 686 708 0.99
13 14 2.2e-06 0.00023 22.4 0.7 1 23 714 736 714 736 0.99
14 14 4.2e-05 0.0045 18.4 0.5 1 23 742 764 742 764 0.97

Sequence Information

Coding Sequence
atgtCTGGTGATATACTTTCCAAATGTCGGACTTGCCTTAGTGCTTGCAACATTTACCACCAACTATTCGATTATGTTgatgaaaattacaaaattcttgAAATGTTGGATGGAATTGTGCCGCAAGTAGATTTTAAGACCTCTTCCCAATTTTCCACACTAGTGTGTCAGCCTTGTGTGGATAAACTTTTGGTCAGCTTTAAATTCCAACAGTTGTGCATTGAAAGCAATAATCGTTTGCATGATTTGCTAGGCATTTCTATCTTTGAGGTGGAACCAAAGTTCGAGAAAATCTTAGATCCATTGACAGGAGAGTCAAGCTTTAAAATGAAACAGGAAGTTGAAGAAGACGCCTGTTTTGAATATGAAATTCATCCAAATGCTTTAAGTGAGGAAATAGAGTCAAAAAATGACAATAAATGGGAACCGCTTGAAGCTGATGGTAGTGGTTCAGATTCTAGCAATGAaaaactttccattttaaaagaACGCTCAACACAAAAGGcacgtttaaaatttaaagtgttgcaaaagccGAGGAATTTAAATGGTCGAAAGGGACACTTTCTCTGTTCTGAATGTGATAAAGTATTTAGCAGTTTAAATCGTCTTAAACGGCATACATCCATACATGAGAGAAAGCGATCGAAAGAGAAAGCTCTTAAAGTTCATAAAACGCATACAAATGGTAATGTTGCCGACGAAGAGGATGAAGTAAAACGAAATGACAGTATTGAGGATAATGAGTTAAAAGAAATCGCTGAGGGGCAGCAGTTTAAAGACAACCTTAAATTGAATGAAACGACGCAAaaggaaaaagaagaagatgaaGAATCTAAGGGATTACTAACGTTTCAATGTCCTGACTGTCAAAagtgttttgataaaaaagctTCGCTTTCGGCTCACTACaaagttcataaaaaaaattcgcattttacaaataaaagtaaaagcgTTAATCGTGAATTGCTTGAAAACCAGAAATGTGACGTTAATGATAAAATTGATAAGTTACCTAAAGTAATTGTGAAGAAGGAATTCGAAGATACACAAATATTTGAAGAATCAATCGATAAATTTGGTGAAAATGGAGAATGGTTAAACCATGATTATAATGATGAGTCAAGTGGATATTCAGAGAAGGAAAGTTTTGCAAAACCTGCTAtcaaagaagcaaaaaatattgattttatagaTACTGGCGTAGGAGAAATAGAAAAgcCCAACATCAGCAACAAACGTAGTGGTTGCTTTCCTTGTGAAGCATGCGGTAAAGTTTTTGATCGTCCCTATCGACTAAAGCGTCATAGTTCTGTTCATTCTTTGACGAGGCCGCACGAATGTGAAATCTGTAAATATCGTTTTGCAACCATCAATATTCTTAAATCTCATCTATGCACACATAAAAACGAGACGGAAGGCTGCAATATTAACTCTACACGTCCAGAAGGTTTTAAATGTCCCGACTGCCCGCGACGTTTCGAGAAACAAGCCTCACTCTCAGCCCATCGACAGACTCACACAAGAAATGCCACCGCAGCTAATTATCCTTGTTTGGTTTGTCAGCGCAATTTTCGTTCTGTGCGGTCCTTAACCGATCATATTACAAACAAACATCCCGAAGTCGAAAAACATAAATGTGATCAGTGCGAAAAAACATTTGTTCTGCATGCCCATCTACTAGAACATTTAAACCGTCACAAaggcaataaaaatttagtgtGTGTTATATGTGAAAAAGAATTTCGTTACACGAATACTTTAAAGGAGCACATGCGTACACATAGTGGCGAAAGCCCCTATCTATGTCCCCAGTGTGGCAAAACATTTCGTAGTGCAAGTAATTTGCGTCAGCATATGGAACGTCATATAGGCTTAAAGAAATACCAATGCCCAGAATGTCCCAGTCGCTTCAACTGTAGATCAGATGTTATTAAGCATTCATCAACACATTCAAATTCAAAGCCTCATGTCTGTGATATATGTGGTTCTCGTTTTACGAGATCATATTCATTGCAAAAACATAAGCTTTTGCATTCAGGCAAAAGACCGTTCAAATGTGATCAGTGTAACATGACGTTTGTAATAATTTATCACTTGCGCCGCCATATGCGCACACATACTGGTGAAAAACCCTACAAATGTAAATACTGTGAACGTGCTTATGCCGAAAGTGGAGATCTAACAAAACACTTGCGAACGCATGTAGGCGAAAATACTTATATGTGTGATCAATGTCCCATGGCCTTTAAATATCAAGCGGAATTAAAAAATCACCAATCTCAACATTATAAAATGGCCCAGAAACTATTGCAAGCTCAACAAAGAGAAAAAGCAGAAAAGCCAAAGCAAGAGGAACCAAATTTGTTGCAACAAACAGAACAGCTTGAACTGCAACATTTTTCAATGCAGGAACAGATTCAGCAGGAGCAACAACATATTCATCCCATGATGAAATGtaatcaaattcaaaatttaccaTCAAGTATTAGTAATTTACAAATGCCGTTAATTGATCATACGCAACAATTAAATGCAATTCAAGAACAAACTTAA
Protein Sequence
MSGDILSKCRTCLSACNIYHQLFDYVDENYKILEMLDGIVPQVDFKTSSQFSTLVCQPCVDKLLVSFKFQQLCIESNNRLHDLLGISIFEVEPKFEKILDPLTGESSFKMKQEVEEDACFEYEIHPNALSEEIESKNDNKWEPLEADGSGSDSSNEKLSILKERSTQKARLKFKVLQKPRNLNGRKGHFLCSECDKVFSSLNRLKRHTSIHERKRSKEKALKVHKTHTNGNVADEEDEVKRNDSIEDNELKEIAEGQQFKDNLKLNETTQKEKEEDEESKGLLTFQCPDCQKCFDKKASLSAHYKVHKKNSHFTNKSKSVNRELLENQKCDVNDKIDKLPKVIVKKEFEDTQIFEESIDKFGENGEWLNHDYNDESSGYSEKESFAKPAIKEAKNIDFIDTGVGEIEKPNISNKRSGCFPCEACGKVFDRPYRLKRHSSVHSLTRPHECEICKYRFATINILKSHLCTHKNETEGCNINSTRPEGFKCPDCPRRFEKQASLSAHRQTHTRNATAANYPCLVCQRNFRSVRSLTDHITNKHPEVEKHKCDQCEKTFVLHAHLLEHLNRHKGNKNLVCVICEKEFRYTNTLKEHMRTHSGESPYLCPQCGKTFRSASNLRQHMERHIGLKKYQCPECPSRFNCRSDVIKHSSTHSNSKPHVCDICGSRFTRSYSLQKHKLLHSGKRPFKCDQCNMTFVIIYHLRRHMRTHTGEKPYKCKYCERAYAESGDLTKHLRTHVGENTYMCDQCPMAFKYQAELKNHQSQHYKMAQKLLQAQQREKAEKPKQEEPNLLQQTEQLELQHFSMQEQIQQEQQHIHPMMKCNQIQNLPSSISNLQMPLIDHTQQLNAIQEQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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