Mror022311.1
Basic Information
- Insect
- Melanophora roralis
- Gene Symbol
- zfh1
- Assembly
- GCA_963583895.1
- Location
- OY757190.1:39207264-39219614[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.06 6.5 8.4 0.1 2 23 239 261 238 261 0.90 2 18 0.91 99 4.7 0.0 6 23 270 287 270 287 0.96 3 18 0.0017 0.18 13.3 0.4 1 23 293 316 293 316 0.96 4 18 0.0016 0.18 13.3 4.8 1 23 326 348 326 348 0.99 5 18 2.5e-05 0.0027 19.1 0.6 2 23 355 377 354 377 0.95 6 18 5.6e-05 0.0061 18.0 1.8 1 23 383 405 383 405 0.97 7 18 0.042 4.6 8.9 1.8 2 23 414 435 413 435 0.97 8 18 0.0014 0.15 13.6 1.6 2 23 441 463 440 463 0.92 9 18 0.00013 0.014 16.8 1.3 2 23 470 491 469 491 0.96 10 18 1.7e-05 0.0018 19.6 1.7 1 23 497 520 497 520 0.98 11 18 0.00029 0.032 15.7 2.3 2 23 541 563 540 563 0.92 12 18 4.5e-06 0.00048 21.4 0.4 2 23 570 591 569 591 0.96 13 18 7.9e-05 0.0085 17.5 3.6 1 23 597 620 597 620 0.98 14 18 3.6e-05 0.0039 18.6 3.5 1 23 663 685 663 685 0.94 15 18 0.048 5.2 8.7 3.0 2 23 694 715 694 715 0.98 16 18 1.1e-05 0.0011 20.2 1.6 1 22 720 741 720 743 0.89 17 18 1.3e-05 0.0014 20.0 0.5 3 23 751 771 750 771 0.99 18 18 1.1e-05 0.0012 20.2 2.4 1 23 777 800 777 800 0.98
Sequence Information
- Coding Sequence
- ATGATATGTCGTTTATGCTTAAAAGGCATTCCAAAAGAATCTAGTATAAAGTTATATGAAAATTTGGATGTTTCGGGTGATTCAATAAAAATGGTCAAACTAATTGAACGATATCTGGAAATtaaaATTAAACAGGATGACATTGTATCCACAATTATATGTCAAGACTGCTCGGACCATTTGGAAGAATTTCATCGTTTTTCTCAACAAGTAGCTGAAAAGCAATTAACGTTGTGTAAAGAGTTTTTAGATTTCAATCTTAAAAAAGAGCACAACATTGATGATGAAGACGCTTGGGACAATGATGATCATGAGAATAACAAAAGCGAACCAAATGAAAAAAGACAAGAGATAATAATCAACTGTCCCCTAAGCATGTTGAAAGATGAAACTGATGATAATGAAAATGATGAACAAGAAATGCCTACAGAAGACCTAATTGAAACTACGGGAAGTAATGAAAAAGATATTATAGCCCCAGATTgtgttgcaatttttaatgaAGACGATAACAGCAGAGATAATAATTACATTCCTGATCAAATTTCTTCAGACGaTGATGATGTTCctcttataaaatttaaatctactaagaaaaaatcacaaaaaaagaaaCGTAAAAAAGCACCAACCAAGCCTCGTGAAATCAAAGAGAAGaaaccaaaaaagaagaaattatccCTACAAGAAGAAGTGGCTATGTCAATGGATCTAATATGTGACATTTGTCAAACCCGTGTTGATACATGGAAGGCCTTAAGAGAACATTTTCTTTTGGCACACACTAAAACACCATATATTAAGTGTTGTGATATTGTTTACCGTAAACCACGAGCTCTCATGGAACATCTCGAGTGGCATAAAAATCCAGATATGTTTAAATGTCAAATTTGTAATCAAAATATGTCCAGCGCTCGCAATTTAACCATACATATTACATCGGAACATCCTGATAAAGCCGACTTGGTAGAGTTTTACGAGTGCGAACATTGCTCAAAACGAATACGCAAttacaacttatttaaaaagcatttacgtTCACACAACAAAGAAACAGAAGTTGAATGTAACATTTGTAATAAAAGattATCATCCCAATATACTCTTGAACGAcatatcaataattttcataaCAATATTCGCAAACACGTCTGCGATATGTGTGGTCGGGTTTATAAAACGAAAACTGCTTTCAAAGATCACTATAATATACATTTGGGTATAGTTTCTCCAGCTGTACAATGCTCTATATGCCATAAATGgcttaaaaatgcaaacagCTTGCGTGTACATCGTTTTACTCATGAAGAACATCACATGTCGTGCGATATATGTGGACTTTCGTTTAATACAAACCGTAGACTGCATAGGCACAAGATCTACTGGCATACATTAGATGCAAATCTACATTGTAGTTTTTGTGATAAAGTCTTTCGCGAAAAACGAAATCTTGATGAACATATGGCTATACATTCTGGGGTTCAATTATATTCATGTCCACATTGCGGAAAGGATTCAAGatcgaaatcaaatatgtacgtacatattaaGCGGATACATCCAAATGAATGGTGGAGATCAAAAATGGAGCGTCTAAATTTAACATCCCAGGACAATGattCTTGCGATTTATGCGGAAAAGTGTTTGAGACTAAACATCGCCTGCGCAAACATAAATCCTACTGGCATAAGTCTGATTTAGACTTGCAGTGTAACTTTTGTGAAAAAGTTTTTCGCCAAGAGCGCAATCTGCAGGAGCATATGGCTATTCATACGGGAGTACAGCTTTACAAATGTCCACATTGTCAGAAAGAATCACGTTCCAAGTCAAATATGTACGTTCATATAAAGAGACAACATCCAAGTGAATGGTGGAAATCCAAAATGGAACGTTTGAATATAAATCCAAATGCTGAAAGTCCAGAATGTGCAACCATATACCGTTTGCGTAACCATATTGCATCCGTTCACAATAACATATATCATCATATTTGTGATATTtgtgggaaaaaatttaaatcgaagACCTCCTTTCAAAAGCACTACGATGAACATCAAGGCATCATTGAACCACCGGCTCAGTGCACAATATGCGGTGCTTGGCTGAAAAATCAACACAGTCTGAAGGTACATCATCAAACTCATGAAGACACACAGTTTGCCTGTGATGTttgtggtaaattttttaagacaaaaaagaaTTTGAGCCGCCACAAAGGATATTGGCATAGACGGGAACGTAATCTGTTGTGCAGCTACTGTGACAAGGTATTTCGTGAAAAACGCAACTTGGACGAGCACATGGCCACGCATACAGATACGAATCTGTATACGTGCCCTCACTGTGGCAAAGAGTCTAGATCAAAGTCcaatatgtatgttcatataaaGCGGCAGCATCCGGATGAATGGTGGAAATCAAAACAGGAACGTTATCAACTAAAACCAGAAGATAGTGGACAGGCTGCAAGTGAAAATCCACTTAAAGAGAAATCAACATTAGCAGCAGCAGATGATACAGTAACAATGGTTCCAACATCAGCATCCCATACACAGGAGTGTTTAAATGCAGGATAA
- Protein Sequence
- MICRLCLKGIPKESSIKLYENLDVSGDSIKMVKLIERYLEIKIKQDDIVSTIICQDCSDHLEEFHRFSQQVAEKQLTLCKEFLDFNLKKEHNIDDEDAWDNDDHENNKSEPNEKRQEIIINCPLSMLKDETDDNENDEQEMPTEDLIETTGSNEKDIIAPDCVAIFNEDDNSRDNNYIPDQISSDDDDVPLIKFKSTKKKSQKKKRKKAPTKPREIKEKKPKKKKLSLQEEVAMSMDLICDICQTRVDTWKALREHFLLAHTKTPYIKCCDIVYRKPRALMEHLEWHKNPDMFKCQICNQNMSSARNLTIHITSEHPDKADLVEFYECEHCSKRIRNYNLFKKHLRSHNKETEVECNICNKRLSSQYTLERHINNFHNNIRKHVCDMCGRVYKTKTAFKDHYNIHLGIVSPAVQCSICHKWLKNANSLRVHRFTHEEHHMSCDICGLSFNTNRRLHRHKIYWHTLDANLHCSFCDKVFREKRNLDEHMAIHSGVQLYSCPHCGKDSRSKSNMYVHIKRIHPNEWWRSKMERLNLTSQDNDSCDLCGKVFETKHRLRKHKSYWHKSDLDLQCNFCEKVFRQERNLQEHMAIHTGVQLYKCPHCQKESRSKSNMYVHIKRQHPSEWWKSKMERLNINPNAESPECATIYRLRNHIASVHNNIYHHICDICGKKFKSKTSFQKHYDEHQGIIEPPAQCTICGAWLKNQHSLKVHHQTHEDTQFACDVCGKFFKTKKNLSRHKGYWHRRERNLLCSYCDKVFREKRNLDEHMATHTDTNLYTCPHCGKESRSKSNMYVHIKRQHPDEWWKSKQERYQLKPEDSGQAASENPLKEKSTLAAADDTVTMVPTSASHTQECLNAG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -