Basic Information

Insect: Melangyna quadrimaculata
Gene Symbol: -
Assembly: GCA_949320155.1
Location: OX439483.1:97473171-97478782[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.5 6.6e+02 3.2 1.8 3 21 651 669 649 673 0.91

2 11 0.016 4.2 10.1 0.5 2 21 695 714 694 715 0.92

3 11 1.7 4.4e+02 3.7 0.5 1 23 735 759 735 759 0.91

4 11 0.16 43 6.9 0.3 1 23 764 788 764 788 0.91

5 11 0.34 88 5.9 0.5 2 23 816 837 815 837 0.96

6 11 2.3e-05 0.006 19.0 2.1 2 23 859 881 859 881 0.98

7 11 0.004 1 12.0 0.0 1 21 886 906 886 907 0.94

8 11 2.9 7.6e+02 3.0 0.1 2 23 944 965 943 965 0.91

9 11 0.0019 0.5 13.0 5.9 2 23 984 1004 983 1004 0.97

10 11 6.6e-06 0.0017 20.7 1.3 1 23 1010 1033 1010 1033 0.96

11 11 0.42 1.1e+02 5.6 0.8 1 12 1061 1072 1061 1073 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.5	6.6e+02	3.2	1.8	3	21	651	669	649	673	0.91
2	11	0.016	4.2	10.1	0.5	2	21	695	714	694	715	0.92
3	11	1.7	4.4e+02	3.7	0.5	1	23	735	759	735	759	0.91
4	11	0.16	43	6.9	0.3	1	23	764	788	764	788	0.91
5	11	0.34	88	5.9	0.5	2	23	816	837	815	837	0.96
6	11	2.3e-05	0.006	19.0	2.1	2	23	859	881	859	881	0.98
7	11	0.004	1	12.0	0.0	1	21	886	906	886	907	0.94
8	11	2.9	7.6e+02	3.0	0.1	2	23	944	965	943	965	0.91
9	11	0.0019	0.5	13.0	5.9	2	23	984	1004	983	1004	0.97
10	11	6.6e-06	0.0017	20.7	1.3	1	23	1010	1033	1010	1033	0.96
11	11	0.42	1.1e+02	5.6	0.8	1	12	1061	1072	1061	1073	0.88

Sequence Information

Coding Sequence: ATGCTGGAAGAGGACCTCGATGATACACACTTGTGCATCAAATGTAGTGCCACAATTGTCGGCCTCGATAATTACGTCCAGCATCGCAAAACAAATTGTGTTGGCATCAAGACCACTACCAACACCACCACCTGCACAAGAGCCGCCATTGTTTCCCATGGCTATGATGGAGGTTTTGAGTATCCGGGAACTTCGGGCGGATATGTGAAGAACGAAGTAGAAGCTGTTGGTGGCAAGACTTCCAAAACTTTAAATGATCCCTATGACTTGCCCTATGAATTGGGTGCAGATGTTTTCTTTTCTTCGTTGCAACTTCAAAGTGTTCAAGCTAGCGGAACTGGCAATGCCGGGAAGACCAGTAGTTCTATTCAGCAGATTTCGGCTAGAAAAGTTGCCAGTTCTGTTGGAAGAGATGAAACTGAAGGTGATGATTGGCATGGCGTGGAACAGAATAATTCGGACAGTTTGATGAAGGTCGTTCGGGATATTGGAGAGACGAAAAAATACGAACCAATATTTAAGCCGATTGCTTTTGCTCACGGATTTCCCGAGGCCGAGCCAAGTGAAGATGAAGATGATGATATTGATGAGTTCGATGAAGATGACGAGGATGATGAAGATTATGTGCCGACTCCGTATTCTGGAGGCAAGTGGAAGCCTGGCAGCCAGCCATCGAGAAGTGGTGGTGGGAAATGGAAGGGCAAAGTCCACCATCAGAATTTCGCTGTTCCGAGTTCGTCAGGTGGTAAATGGCATAACAAGTATGTTGCCAATGAGAGCAGAAATAAGTGGAAACCTTTCAAAAAGAACTCGGAACCATACTATCAtcaaaatcatgcaaaaatCACGTTGAAAAAAGATGCCTCACCAAAAGTTGAGCCTGAGGTTCCACAAAGTGGTGGCAAGTGGAAACCTGAAAGCCCAACGAAAGCATTGAAAACACCGCAAATTCAGCTAAGTGGTGGCAAATGGAAGTCGCCTGAGGAGATTCAGTCGCCAGAAGATGAAGCACCCGCCATCACTGGAGGCAAGTGGAAGCCAGAAGATGGTCCTTCAACAAGTGGCAAATGGAAACCGGAAGATGGGCCATCAACTGGAGGCAAGTGGAAACCTGAAGATGGTCCATCAACTAGTGGTAAATGGAAACTGGAAGATGGTCCATCAGCTAGTGGCAAATGGAAAACTGAAGATGGTCCATCAACTAGTGGCAAATGGAAAATCGACGATGGCCCATCAACTAGTGGAAAATGGAAACAAGGTGATTTACAAAGTTCGAAAATACTTTCACCACAAAGTGTGATGAAATGGGATGAGCCACCAGAAGTGTGGGAAGATGTTGACAATGTTCATCCACCAGTTGAGCACACCAAAGGCAAATGGGTTCCaggaacaaaatttgaaaaaatcgacTACAAAAATGAGaatCTCCCACCAACACCTCAAGACTACTGGTGTAACATTTGCTGTCGCAAACTCAagacaaaaacaattttcgacAAACACCTTAAATCCGCGGTGCATTTAAAGAAATCCGAAACCGAAGAGCAACTAGAACGTGCCGGAGTAAATAAACAACTTGAAGTCTCTTCGCAAATCCTCCAACCTGTTCCTCCAGAATTTCTCTTGAAACCAAATATCTCACCCGAACCACCATTGGATCCAAACAAACGAAAACGACGGAAAACCTTTGTAAAGTGTAAAGTATGCAATCATCGAATGCAAAGTTACTTAATGGGTAAACATTTGATATCTCACTATCACTATGTTCGAAGAGTTGGAGATCTGGCGAAATCATATGGCATGGTTCTTGATAACATCAATCAGATAGTTCTACAATCGCCATTCCAGTGCGGCCCCTGTAGATTCTATGCCAATGACGAAGAAAATTTCCTTGACCATTGGAACTCTGTGGAGCATCGCGATCGAACTGAAGGTCCTGGGAAGTTTTGGTGCAGCTTTTGCCAGTTCGAATGTGAGGACAACAATCAAATGAGACGTCACCTCCTGGGCAGTGACCATCGGGAAGTCATAATGGCTATAAATCGATCAGTTCCGATAATCATCAGTAAAAAAGTCTCCATCGAATGTCTCAAGTGCCATCAAAACTTTCGGTATAACATTGAATTGCGCCAGCATGTACTTCGATGTGAGGGGGTCAAGACTGAAGCAATTGGGACAGCATCGGATGAATATCAGTCAAGGTTTCGATGTGCTCTGTGTCCCAATGAAGTTCTCAAGTCTAAAATGGCACTTCAGAGGCATGAAAAGTTCAAGCACAATAAACGACGGTTCTATTGCTCGATTTGCAATGAAGAGTTTCTGAGCCCTGAGGCAGCTATTAAACACCGCAAGACCAAGTTGCATCGACAAAATTCCAATACCAAGTTGAATAGGAAGAATGAGGAGAGAATCATCAAGGTCAAGGTGGAACCTGAAGACGATTTGAAATGCGAAAAGTGTAACCATGTATCGTCTTCGGAAGTTGAGGCTATGTTACACCAAATCAGCCATCCTGAGGGCTGTAAGAAGACCCAAGAAAAAGACAAGAAAGTCTCAATAGAAATCCGTATGAGAAAGTGCCATTTCTGCAAAGCCACATTCCCAACTAAATCCGAACTGAAAGCTCATCTCAATACAGTCCACCCGGAATTGAAACACGTCTGCCCACTTTGTGGAGAAGCCTTCACTCTGCCTCAAGAACTTGGTTCCCATAGGAGATACAAAATATGTGTGGCCTCCACTTCAACCAAAAAACCATCACCAATGACCATCGAAACAACTAcctcatcaccatcatcatcccAAAAAGATCCAAAGAAGCAATCTTGGATATGTTCAGATTGCACATTTAGCTCTGCCTATGAATCGGAGTTGATGTTCCATCGGATTATCCATACAGAGGGTGGTTTGGAGGCACTCGAATCGTCCTCGTCGGCTGGCACAAAAATTAAATGCGAACTTTGTGAGAAATCATTTACGAAGCATTCACTTCGACATCATTTGCGTCAGCATACCAACGAAAAGATTTTCCAATGTGAAATTTGTAAACGGTCATTTGCGAGGCGAAATAATTACAAGGAGCATATGGAATACGTGCATGCGGTTGGGGGTGCAGTAAGGAAACGCCACAAGGGTGGTAGTGGTGGTGGCGGTCCCAGCGGACGATCAACGGATGAGCGTTTTGTGTGCGATACATGTGGCAAGATATTTGGGACAAAGTGa
Protein Sequence: MLEEDLDDTHLCIKCSATIVGLDNYVQHRKTNCVGIKTTTNTTTCTRAAIVSHGYDGGFEYPGTSGGYVKNEVEAVGGKTSKTLNDPYDLPYELGADVFFSSLQLQSVQASGTGNAGKTSSSIQQISARKVASSVGRDETEGDDWHGVEQNNSDSLMKVVRDIGETKKYEPIFKPIAFAHGFPEAEPSEDEDDDIDEFDEDDEDDEDYVPTPYSGGKWKPGSQPSRSGGGKWKGKVHHQNFAVPSSSGGKWHNKYVANESRNKWKPFKKNSEPYYHQNHAKITLKKDASPKVEPEVPQSGGKWKPESPTKALKTPQIQLSGGKWKSPEEIQSPEDEAPAITGGKWKPEDGPSTSGKWKPEDGPSTGGKWKPEDGPSTSGKWKLEDGPSASGKWKTEDGPSTSGKWKIDDGPSTSGKWKQGDLQSSKILSPQSVMKWDEPPEVWEDVDNVHPPVEHTKGKWVPGTKFEKIDYKNENLPPTPQDYWCNICCRKLKTKTIFDKHLKSAVHLKKSETEEQLERAGVNKQLEVSSQILQPVPPEFLLKPNISPEPPLDPNKRKRRKTFVKCKVCNHRMQSYLMGKHLISHYHYVRRVGDLAKSYGMVLDNINQIVLQSPFQCGPCRFYANDEENFLDHWNSVEHRDRTEGPGKFWCSFCQFECEDNNQMRRHLLGSDHREVIMAINRSVPIIISKKVSIECLKCHQNFRYNIELRQHVLRCEGVKTEAIGTASDEYQSRFRCALCPNEVLKSKMALQRHEKFKHNKRRFYCSICNEEFLSPEAAIKHRKTKLHRQNSNTKLNRKNEERIIKVKVEPEDDLKCEKCNHVSSSEVEAMLHQISHPEGCKKTQEKDKKVSIEIRMRKCHFCKATFPTKSELKAHLNTVHPELKHVCPLCGEAFTLPQELGSHRRYKICVASTSTKKPSPMTIETTTSSPSSSQKDPKKQSWICSDCTFSSAYESELMFHRIIHTEGGLEALESSSSAGTKIKCELCEKSFTKHSLRHHLRQHTNEKIFQCEICKRSFARRNNYKEHMEYVHAVGGAVRKRHKGGSGGGGPSGRSTDERFVCDTCGKIFGTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -