Basic Information

Insect: Melangyna quadrimaculata
Gene Symbol: ZBTB41
Assembly: GCA_949320155.1
Location: OX439484.1:4132105-4134993[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 8.3e-06 0.0022 20.4 4.3 1 23 175 198 175 198 0.97

2 8 0.00053 0.14 14.7 0.2 2 23 348 369 347 369 0.97

3 8 0.028 7.3 9.3 1.6 1 23 373 396 373 396 0.96

4 8 0.0033 0.86 12.3 1.1 1 23 407 429 407 429 0.98

5 8 0.61 1.6e+02 5.1 2.8 1 23 451 473 451 475 0.88

6 8 0.00013 0.034 16.7 0.3 1 23 479 501 479 501 0.99

7 8 1.9e-05 0.005 19.3 3.5 1 23 506 528 506 528 0.98

8 8 0.027 7 9.4 6.1 1 23 534 557 534 557 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	8.3e-06	0.0022	20.4	4.3	1	23	175	198	175	198	0.97
2	8	0.00053	0.14	14.7	0.2	2	23	348	369	347	369	0.97
3	8	0.028	7.3	9.3	1.6	1	23	373	396	373	396	0.96
4	8	0.0033	0.86	12.3	1.1	1	23	407	429	407	429	0.98
5	8	0.61	1.6e+02	5.1	2.8	1	23	451	473	451	475	0.88
6	8	0.00013	0.034	16.7	0.3	1	23	479	501	479	501	0.99
7	8	1.9e-05	0.005	19.3	3.5	1	23	506	528	506	528	0.98
8	8	0.027	7	9.4	6.1	1	23	534	557	534	557	0.97

Sequence Information

Coding Sequence: ATGACTGAAGTTCGTTGCGATAATTGCAatGAAATAAACGATATTAATGCTGTTAAATGTGAAACTTGTAAAATTAGCCTTAAAATAACTGAATCTTTATGCTCCGAAGACGATGAATGCGAAAGTGATTTCCGTTTCATCGAGGAAGCTGAATTTATTGGTGAAGTTTATAAATTAGAGAATTTAGATGAATGTGAAGAAGGCAATCATGGGCAGGGCATAAAATATGAACCTTTCGATGCAAATATCTGTTGTCAAATTCCTGATGCTTATGTGGAGAGCATTGTTAAATTGGAGGATGATGATACTGATAATGTCACATTCGAAATTGTCACTGTTGAGCCGCAATTGGTTGGTGACAATGGAAATGagacaaagtttgaaaataaaaagaatttagatGTTAATGACAATGCCACAGAAAAGAGTCAAattccaaaaacaaaagtcaatagGTCACAAAACGTTAAGATCAAAACTATTGCAACAGAGGAGCCCGAAACAACTACCCCAAGAGTACCATACCAGTGCACACAATGTTCAAAAAGttttaaaagAAAAGCCACTTTAAAGGCCCATGTTCACCGAACACACAATCCAGATGATGTAAGTGCCTGCTGTGCTGGCCATTTCTCGGAAAAGGAATCCAAACTAAATTGCCACGAAGCTTCAACTCCATTCTCCGAATCCTGTGAATCTGAATATTTATATTCGGGCGACGAAACCGAAAAGCATTCAATTCCTATAAAACAATCAAGCTCctcacaaaaaagaaaacgaaaaccCAAACATGAATCTGATTCAGAAAACAATAACTCACGAAAAAAGTCGCCCAAAAAGTGCAAAACAGAACTAAGTCCTTGTtctaattcaaaacaaaataaatcaaatgaaaTTGTTTACAAATGTGCAGCGTGTGAGAAAATCACAGATAGCTACCAAGAGCACTTGAAGCACATAGTAATTCACGAGAAAGTAGATGATAGTCTTACAGTGACAACTTCTCTGGAGCAACTTAAGCAGACCCCGAGTGGCTTTCTGGAGTGCAAAGAATGTGGAGGGGTATTCATGAGCGAGCGGGAATATAACATTCATCAAAGATCCCATCAAGGAGTTCATCAATGTGACATTTGCAAGACAATCCTTTTGACACCGTCAAGTCTCAGAAAGCATAAACTTCGGATGCATCGGCAAAGGTCCAGCAGGAAAGGGACATTGTTTGAATGTAATATTTGCAATGAAAaATATGAGTCTCAGTTACTTATGTTGCAGCACAGAAAAAAACACACTGAGGTAATGAAGAAAATCGAAGAGATGACCATCATCGACCGAAGCGGAGGAAAAACTTGCTACGTGTGTAAAATATGCGCAAAAACTTCAAATAACAAATTCAGACACGAGGAGCATTTGAGAattcacacaaaagaaaaaccgtataaatgtgaaaagtgtgGAATTGGCATTGCAACATCGAATGCAATGGCCCATCACATGCGAACCCATGAAAATGTAACATTCGAATGCAACGTTTGTGATGCCACATATCGACACAAGAAGAGTTTGAAAAAACACTTGAAACTGCATACTGGTGAGAGGCCATTTGAGTGTCGCCATTGTGATAAAACGTTTGCCTTTAACTACACACGGGCCGACCATGAACGCAAATGCCACATAGATGGTGGCACATCTCGGATACAGAAAAGAAAACGTAAGGGAAATTCTGCTAAAAAGTCGAATGAAAGTGAAAATGAGAACAAAGATTCACCACAAAATGGACCAACAACTGAAGTGGTTACAAATGATAGAGAATGTCCGACAGGTCTAGAGGAAGTTGATATAGTATAA
Protein Sequence: MTEVRCDNCNEINDINAVKCETCKISLKITESLCSEDDECESDFRFIEEAEFIGEVYKLENLDECEEGNHGQGIKYEPFDANICCQIPDAYVESIVKLEDDDTDNVTFEIVTVEPQLVGDNGNETKFENKKNLDVNDNATEKSQIPKTKVNRSQNVKIKTIATEEPETTTPRVPYQCTQCSKSFKRKATLKAHVHRTHNPDDVSACCAGHFSEKESKLNCHEASTPFSESCESEYLYSGDETEKHSIPIKQSSSSQKRKRKPKHESDSENNNSRKKSPKKCKTELSPCSNSKQNKSNEIVYKCAACEKITDSYQEHLKHIVIHEKVDDSLTVTTSLEQLKQTPSGFLECKECGGVFMSEREYNIHQRSHQGVHQCDICKTILLTPSSLRKHKLRMHRQRSSRKGTLFECNICNEKYESQLLMLQHRKKHTEVMKKIEEMTIIDRSGGKTCYVCKICAKTSNNKFRHEEHLRIHTKEKPYKCEKCGIGIATSNAMAHHMRTHENVTFECNVCDATYRHKKSLKKHLKLHTGERPFECRHCDKTFAFNYTRADHERKCHIDGGTSRIQKRKRKGNSAKKSNESENENKDSPQNGPTTEVVTNDRECPTGLEEVDIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00665230;
90% Identity: -
80% Identity: -