Basic Information

Insect: Melangyna quadrimaculata
Gene Symbol: Kr-h1
Assembly: GCA_949320155.1
Location: OX439483.1:138412460-138414708[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.004 1 12.0 3.0 1 23 152 174 152 174 0.98

2 8 1.7e-06 0.00044 22.6 0.5 1 23 213 235 213 235 0.99

3 8 2e-05 0.0053 19.2 2.3 1 23 241 263 241 263 0.98

4 8 4.4e-07 0.00011 24.5 2.8 1 23 269 291 269 291 0.99

5 8 4e-08 1e-05 27.7 1.1 1 23 297 319 297 319 0.98

6 8 0.00013 0.034 16.7 1.5 1 23 325 349 325 349 0.99

7 8 0.58 1.5e+02 5.2 3.7 1 23 355 377 355 377 0.94

8 8 4.2e-06 0.0011 21.4 0.5 1 23 383 405 383 405 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.004	1	12.0	3.0	1	23	152	174	152	174	0.98
2	8	1.7e-06	0.00044	22.6	0.5	1	23	213	235	213	235	0.99
3	8	2e-05	0.0053	19.2	2.3	1	23	241	263	241	263	0.98
4	8	4.4e-07	0.00011	24.5	2.8	1	23	269	291	269	291	0.99
5	8	4e-08	1e-05	27.7	1.1	1	23	297	319	297	319	0.98
6	8	0.00013	0.034	16.7	1.5	1	23	325	349	325	349	0.99
7	8	0.58	1.5e+02	5.2	3.7	1	23	355	377	355	377	0.94
8	8	4.2e-06	0.0011	21.4	0.5	1	23	383	405	383	405	0.98

Sequence Information

Coding Sequence: ATGGTTTACTATCCATCGTTGCCGTTAGTTATGAAAACCGAACCAATATCACAATCAGAATTCTGTTTACCACTAACGAGCAGTGCGAGTGGTATCAGTGACAGCCAAATGTACCAACAATCAACAAACATGATTGTGCAACAGCCAATAACAAGTATTAGAAATCGCATTGGAGGTGGACTGCcttcaacatcatcatcatcattattatcATCACCGCCAACATCAGTATCATCTGGTGGGAGTGAAACTCTGATAATATCACCACATCATGATGTTCAAACATTTCAAATTAGCGACGGACAAAATATAACCATCTACACAACGACGCAAACGACACAAGAAAGTATTCTCCCAACAACATCTGCACCAACAACAGCTACAACAACAAATAACGGACGAAAGTCCTCTCCCGCGTCTGTCAAATCAACAACATCACCAACAAAACCCCAGTTTAAGTGTGAACAATGTGGAATGACTTTCGGCAGTAAAAGCGCCCACACAAGTCACACCAAATCGCATGCGAAGATCGAAGGAGCGGGAGGAGTTGCAATGGTATCGCAGCAAATCAATGAGATTCCAGCGGGTATACCCAAAACCCCACAAATTAAGGCTAACGGAAGTGGGAGTGATCCGTACCAGTGTAATGTGTGTCAGAAGACCTTTGCTGTGCCTGCTAGACTGATCCGCCATTATCGTACACATACGGGTGAACGGCCTTTCGAGTGCGAATTCTGTCATAAACTTTTCAGTGTTAAGGAGAACCTCCAGGTTCATCGACGCATTCACACGAAAGAGCGACCCTACAAGTGCGATGTGTGTGGCCGCGCTTTCGAGCACAGCGGAAAACTACACCGACATATGCGGATCCACACGGGCGAACGTCCCCACAAGTGCTCAGTTTGCGGAAAGACATTCATACAGTCTGGCCAGCTGGTGATCCATATGCGAACGCATACCGGCGAAAAACCCTACAAATGCCCTGTCGAGGGTTGTGGCAAGGGTTTCACCTGCTCCAAGCAACTGAAAGTCCATTCGCGCACCCATACCGGAGAGAAACCCTACCATTGTGATATCTGCTTCCGGGATTTCGGCTACAATCATGTCCTTAAGCTGCATCGAGTGCAGCACTATGGGTCCAAGTGCTACAAATGCACCATCTGCGAAGAGACTTTCAAGAGCAAAAAAGAAATGGAGGCCCACATAAAGGGCCATGCGAATGAAGTGCCCGACGATGAGGAGAACCCCAGCGGCAGCAATCAGAATCAAGCTCCAAGTTCACCGATCTCAATGGCTGTAAAACAGAGCCCTCATTCGCCAAGTTCACCGTCGTCATCTTCGATAATTCTTGAGACTGATCAAAGCCGCGACAGCGGTGTTGCCATTTCTACCAGTTCCAATAACACTGGCAGCAGTAGCACCTCATTGGATGAGATGCCACTAGAGATACAAGCTGAacttcagcagcagaaccatcACAAACGTcaccaaaaccaaaaacagcAGCTGCAACAATTGCTCGACGATCAGCGGCCTCACCAGGCAAAGGAAATGATCTCGTTTAGCAATGTCTACCACAGGTATCAGGCAAGATCGGCGTCGCCATCAGAGGAGAAGCATCAGATAGCACAGGAAATGCAACAATATGTCGGAAGACCAACAATCAATCCGGCTTTATTAGAAGCTGCATCGTTGGCGAGTCGAAGAGTCCTCGAGGAGGATACTCTAAAGAATGGCAGAAGAATAAACTCACGAAATGAAACCGAAGATCTGCGAAGTAGTGCAGGTCCGCGGCAGAGTTATTATACACCAGCACCGGTTGGAGAATTCAGATCCTCTCTTCCTGGTAATGACATAGTACGTCAAGTGGAAGCAGCGATTGCTGGTGCAGGCTTATCACCCCTACGATCAGCATCCTCAGCATCACCCGAACGATCTTCATCGCCAGAGAGTGATTCAATGATGATGGCAGATCGTGATGTCATGACACTGCCATTACGCAAACGCAAACTCTACTTAAAGGACAACCAATCTTCGAAGACTGAAGTTCCAAAAGTTATGCGAATGAGTTCGGTAATACAATTTGCTAAGGCATCataa
Protein Sequence: MVYYPSLPLVMKTEPISQSEFCLPLTSSASGISDSQMYQQSTNMIVQQPITSIRNRIGGGLPSTSSSSLLSSPPTSVSSGGSETLIISPHHDVQTFQISDGQNITIYTTTQTTQESILPTTSAPTTATTTNNGRKSSPASVKSTTSPTKPQFKCEQCGMTFGSKSAHTSHTKSHAKIEGAGGVAMVSQQINEIPAGIPKTPQIKANGSGSDPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCGKTFIQSGQLVIHMRTHTGEKPYKCPVEGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICEETFKSKKEMEAHIKGHANEVPDDEENPSGSNQNQAPSSPISMAVKQSPHSPSSPSSSSIILETDQSRDSGVAISTSSNNTGSSSTSLDEMPLEIQAELQQQNHHKRHQNQKQQLQQLLDDQRPHQAKEMISFSNVYHRYQARSASPSEEKHQIAQEMQQYVGRPTINPALLEAASLASRRVLEEDTLKNGRRINSRNETEDLRSSAGPRQSYYTPAPVGEFRSSLPGNDIVRQVEAAIAGAGLSPLRSASSASPERSSSPESDSMMMADRDVMTLPLRKRKLYLKDNQSSKTEVPKVMRMSSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00976794;
90% Identity: iTF_00664329; iTF_01396804; iTF_00335338; iTF_00665112; iTF_00427545; iTF_00694923;
80% Identity: -