Mqua055502.1
Basic Information
- Insect
- Melangyna quadrimaculata
- Gene Symbol
- topi
- Assembly
- GCA_949320155.1
- Location
- OX439484.1:196817094-196818398[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 2.9e-05 0.0075 18.7 1.9 2 23 168 189 167 189 0.97 2 9 0.00018 0.047 16.2 0.5 1 23 195 218 195 218 0.95 3 9 2.4e-05 0.0063 19.0 1.8 2 23 227 251 226 251 0.93 4 9 0.018 4.7 9.9 0.2 1 23 262 284 262 284 0.94 5 9 1.7e-05 0.0043 19.5 4.8 1 23 291 313 291 313 0.98 6 9 1.2e-05 0.0032 19.9 2.1 1 23 319 341 319 341 0.98 7 9 4.1e-05 0.011 18.2 0.4 1 23 347 370 347 370 0.95 8 9 6.2e-05 0.016 17.7 3.3 1 23 376 398 376 398 0.98 9 9 3.1e-05 0.0082 18.6 3.8 1 23 404 426 404 426 0.97
Sequence Information
- Coding Sequence
- ATGGATATTTATTACGATATATTCGCAATATCAGATCTCCAAGAGAAATTGACTGCATGCTCTTCATTGCCTGTGGAACCAGGAGATGGTCTTCCAACAAGCTTATGTGAATCATGTCTTAACAAGAttaatgatttttatatttttcaacaaatgtGCATCTCCGCTAGGAAACGATTTCAAGACTATATAAGTTCAGAAAGAAAACCGTGTTCGATGGAATTAGCCATTCATCCAAACAACCCAACGGATTTTATGATATTCACCGTAGCTAAGAAGGAATTCAAAGACTACGAAGATCCTTTATCGCCTAACGTGCATGACCAAACTGAAACCTCATCAAATGAAGCAGACAACTTCAAAGAAAGCCCTTCACCAAATGGTGAATATAATAAGAAtgttaaaagtaatttcagtacCGATAAGAGCAGAACGATAGAAAATAATGGTACATTGATATGCCACAAGAAACCAAATGCTCATTTAACTAACCAAAGCATCGAATGTGAGATCTGTAAGaaatgttttaagaaaatcgaaacttttgAGGTACATATGCGCTTGCATAAAGGACTCAAACCATTTCCCTGCCAACTGTGTGAGAAATCATATGCACGTCGAGAGCGACTTAAATTGCACATAAAAGCTTACCACGAGCAAAGGCCTGACGAAAGTTTCCTCTGCACTGAGATGGGGTGCGACAGAAAATTTACCAGTAAACAAACTCTCCGGCAACACATCAGGAAAACACACTGGAAAAATGGCAAGAAACCCAAGCAACGCTATATTTGTGAAGAGTGCGGAAAAGTTCAAACAGGCTTAAACGCCCTCAAAAATCATCGCTACTTACACACTGGACAGCAACTGCCGCACGAGTGTCCACAATGTCACAAAAGGTTCATAACGAACAACAAACTTAAGGAACACATAAACCGACACGATGGCATCAAGAACTACATATGTCCGCATTGTGGGACTAAAAGAACAACACGAATGGACTTGAAGAGACACATCAACTCtcacacaaaagaaaagaagtACCTGTGTCAGATCTGTGATATGGTATATTATAATGTGTATAACCTTAATCGACACAAACGGATTGTTCACGAGGGTATGAAGGACTTTCAATGTTCCTATTGTGATAAATCATTTGGCAGGGCAGAGACGAGGAAGCATCACGAAATGACCCATACTGGGGAAAAGCCACACGAATGCAATATATGCCATAAAAAGTTTATCCAAATTATTTCTCTCAAGAAACatcaaaatgttcatttgaaaagactgaaaaaagagaaataa
- Protein Sequence
- MDIYYDIFAISDLQEKLTACSSLPVEPGDGLPTSLCESCLNKINDFYIFQQMCISARKRFQDYISSERKPCSMELAIHPNNPTDFMIFTVAKKEFKDYEDPLSPNVHDQTETSSNEADNFKESPSPNGEYNKNVKSNFSTDKSRTIENNGTLICHKKPNAHLTNQSIECEICKKCFKKIETFEVHMRLHKGLKPFPCQLCEKSYARRERLKLHIKAYHEQRPDESFLCTEMGCDRKFTSKQTLRQHIRKTHWKNGKKPKQRYICEECGKVQTGLNALKNHRYLHTGQQLPHECPQCHKRFITNNKLKEHINRHDGIKNYICPHCGTKRTTRMDLKRHINSHTKEKKYLCQICDMVYYNVYNLNRHKRIVHEGMKDFQCSYCDKSFGRAETRKHHEMTHTGEKPHECNICHKKFIQIISLKKHQNVHLKRLKKEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -