Mqua010442.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melangyna quadrimaculata
Gene Symbol
ECU03_0790
Assembly
GCA_949320155.1
Location
OX439483.1:160124148-160127159[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.049 13 8.6 0.3 3 23 77 98 75 98 0.95
2 20 0.0012 0.32 13.6 0.8 1 23 104 126 104 126 0.98
3 20 0.00017 0.045 16.3 1.4 2 23 135 156 134 156 0.98
4 20 0.00089 0.23 14.0 0.8 1 23 162 185 162 185 0.96
5 20 0.00029 0.074 15.6 4.4 1 23 217 239 217 239 0.95
6 20 1.9e-06 0.00049 22.5 1.0 1 23 245 267 245 267 0.98
7 20 3.9e-07 0.0001 24.6 1.9 1 23 273 296 273 296 0.98
8 20 0.0087 2.3 10.9 2.0 1 23 306 329 306 329 0.95
9 20 9.2e-07 0.00024 23.4 1.6 3 23 429 449 427 449 0.97
10 20 0.00061 0.16 14.6 1.3 1 23 455 477 455 477 0.99
11 20 0.0012 0.32 13.6 0.5 1 23 488 512 488 512 0.97
12 20 0.0044 1.1 11.9 1.4 1 20 518 537 518 539 0.93
13 20 0.38 1e+02 5.8 3.4 1 23 577 599 577 599 0.97
14 20 2.3e-06 0.00061 22.2 1.3 1 23 605 627 605 627 0.99
15 20 0.00017 0.045 16.3 2.5 1 23 633 655 633 655 0.97
16 20 3.1e-05 0.008 18.6 2.8 1 23 661 683 661 683 0.97
17 20 1.6e-07 4.1e-05 25.9 1.7 1 23 792 814 792 814 0.98
18 20 0.00017 0.044 16.3 2.2 1 23 820 842 820 842 0.99
19 20 1.4e-05 0.0038 19.7 0.6 1 23 849 871 849 871 0.97
20 20 0.00085 0.22 14.1 4.3 1 23 877 899 877 900 0.95

Sequence Information

Coding Sequence
ATGGATTGTTTTACTGTCCCAGAAATCATCGACATTCCACCACCCATAGTTGGCTTGAGTCCAATTCCCGAAGAGACTAGTTGCTCGTTAATGGTAAATTCATTGGAACCATTATTTTCTCGTGTGGAAACAGCTTCTTCATCGGCTCCTAAATTTATTATACCCAATTCAAATCAAGATGAACCACCACCAATGCCACCCCCAGCTCAAGCGGTTAAACAACTCGCATGTGATCTGTGCGAAGAGACTTTCTTCTCAACTCAAGTTCTTCGTCTTCATAGGCGAGTTCAACACATATCAACGAAAGAATTTCGCTGCCGCAAATGCCCATCATCGTTTAATTTTGAATCGAATCTTCTCTTACATCTGGCATCACATGTTCCCAGTTGTAGTACCCAGAAGCAATGTCCTGAGTGTAAAATGATTTTCAAACGTATTTCCAGCTTTAAGGGTCATTTGAAAACACACCAAACTAGCGATCGATTTAAATGCAATCGTTGTGACAAGGAATTCGAATTGAAGGGCTACTATGAACAACATCTGGCGAAGGCACACAAGCCGGGAGCTGATGGTGCAATCGAGGAGATTCTATTGAAAGCGgcaaataaaacaaaacgacGAAGGCCATCCAAGCAAGTCAATGGCAAATATCGTTGTCAATATTGTGAGAAGAAATTCACTAAACCTTGTTTGTTGAAACGACATGAAGTTTCTCACACCGGGGCAAAGCCGTTTCAATGTAGCCAGTGCGATCAGGGATTCACACAAAAGTCTTCTCTCGACAGGCATATGCTTCTGCATCAGGGTGTTAAAGATTTCAAATGTCCTATGTGCAGTTATAGCTTTTCTCAAAAGAACAACCTAATTAAACACATTCAACGAACTCATCCAATCAACGCTAATGACGAAAATATGTTTGCTTGTGAATTTTGTTCGTGTGTGTTTACAAAATTAAGCAGCGTGAATCGTCATCGGGCAATGATGCATTCAGAAAAAGACCACCCAGCTGCCGCCGGTCAGGATGGATTCAATGGTAATGATGCcaacgacgatgatgatgacaaTGTAAATGTTGCAAGagttatggaacaattgaagaGTTTTCAAGAATCTATGGGAATTATGGATATGAAACCACCTGCATTAGAACTTTCCCTACTGAAACCGCCATCACCTGGACCAATAGTCAATACGGTCActattgttgatgccataaatcCGAAGAAAGAGAAGACTTTTAAAAAAGTCAAAGAAATAATTTACAAAGGAGAACGAACAATTGCTTGTGTGTATTGTGATAAACCATTTAAGAGGCAGTATGATCTCTTGAGACATCATCGCACACACACCAAAGAGAAGCCATATCAGTGTAATGTTTGCATTAAAAGCTTCTCCTCAAATAGCGGCCTTAAATTTCATCTCAACACTCACATTTCATCTGAAGTCAAACCGGCTAGAGCTTATGAATGTGCGGCAGATGAGTGTCATAAGCGTTTCGCATCATTGCGTGCATTGGATATTCATACaaaAACCCACACAAATTCCATATCATACATTTGTCCTGTCTGTTCGAAAATTTTCACATCCAAAGCTGGTTTCTCTTCGcataagcatcatacaaaagaTCAAGAATTTGATAGTGTTCGTGAGCTTTTAATGGCTCCCGTACAAATTGAAACCAACAGTGCCGAGGAAGCCTACAAAGCCGAAGAGTATCTGAAGAGAAGCCATCAGTGTTTTGTGTGTGGCttgaaaatgcaaaaattatCCCATCTGCGGCAGCATGAAGCTACCCATACGGGAGAGAAACCATATCAATGTGAAATTTGTTTTAGGACCTACACAACACAGAGTTCTCTCAATCTTCATCTGAAAATCCACACAGCCGAGAAAACTCACGTTTGCCAGCGGTGCAATGCCAAGTTCTTTACACAATCCCTACTTATGCGACACATGATCTCACACAGTGATGAACGAAACTTTGCCTGTCCCTATTGCGATGAACGTTTCAAAACCAAAGACAATTGCAAGAATCATATTTTAACCCATGCCCGGAGTTTGTTGGCAAGCCCTGACCCTCAACCGTCACCGTCACCGTCACCGCCTGGGACACGTGAATATGTCGTTGATCCTTATGCAATTCCACAAGACCAACCTGCTGTAATTTCCATCACTCAGAAATTTATTGCAGTTGTTGAGAGTCCCGAGAAGAATCTCTCACCAAAATTCCTTCAACTTGAATTGGTGAAAAATTGCAAAACGCACAAGCACAAGAATTTGATAATCGACACGCTGACGACAACACCAAAGAAAACAACTACAACCTCCAAGAAATCACTAGCACGATCGGTCAAGCAGATTACTCAGACCGGACACAAATGCAATGTATGTGGAAAGATTTTCTTCAAAGCCAGTGATTTGGAACGTCACATTCGAACTCATACAAAGGAAAAGCCATATCAGTGTAGTGTGTGTTCGAGGCAGTTTGCATTAATGTCCACTTTGGTGCATCATATGAAGACACATGATTCGCAGAGAGAGACTTTTGATTGTCAGGTTTGTGGGAAGAAGTATACATCGCAGAAAGTTCTGACGGTGCATTTGCGAATTCATACGGGCGAGAGACCATTTCAGTGTGGTGTGTGTAAGAAGACGTTTCGAACTTCAGGACATAAGATTTCACACGTGAAGGCACATCATAAAAAGAGAAAGTAG
Protein Sequence
MDCFTVPEIIDIPPPIVGLSPIPEETSCSLMVNSLEPLFSRVETASSSAPKFIIPNSNQDEPPPMPPPAQAVKQLACDLCEETFFSTQVLRLHRRVQHISTKEFRCRKCPSSFNFESNLLLHLASHVPSCSTQKQCPECKMIFKRISSFKGHLKTHQTSDRFKCNRCDKEFELKGYYEQHLAKAHKPGADGAIEEILLKAANKTKRRRPSKQVNGKYRCQYCEKKFTKPCLLKRHEVSHTGAKPFQCSQCDQGFTQKSSLDRHMLLHQGVKDFKCPMCSYSFSQKNNLIKHIQRTHPINANDENMFACEFCSCVFTKLSSVNRHRAMMHSEKDHPAAAGQDGFNGNDANDDDDDNVNVARVMEQLKSFQESMGIMDMKPPALELSLLKPPSPGPIVNTVTIVDAINPKKEKTFKKVKEIIYKGERTIACVYCDKPFKRQYDLLRHHRTHTKEKPYQCNVCIKSFSSNSGLKFHLNTHISSEVKPARAYECAADECHKRFASLRALDIHTKTHTNSISYICPVCSKIFTSKAGFSSHKHHTKDQEFDSVRELLMAPVQIETNSAEEAYKAEEYLKRSHQCFVCGLKMQKLSHLRQHEATHTGEKPYQCEICFRTYTTQSSLNLHLKIHTAEKTHVCQRCNAKFFTQSLLMRHMISHSDERNFACPYCDERFKTKDNCKNHILTHARSLLASPDPQPSPSPSPPGTREYVVDPYAIPQDQPAVISITQKFIAVVESPEKNLSPKFLQLELVKNCKTHKHKNLIIDTLTTTPKKTTTTSKKSLARSVKQITQTGHKCNVCGKIFFKASDLERHIRTHTKEKPYQCSVCSRQFALMSTLVHHMKTHDSQRETFDCQVCGKKYTSQKVLTVHLRIHTGERPFQCGVCKKTFRTSGHKISHVKAHHKKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00664262;
90% Identity
-
80% Identity
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