Basic Information

Insect: Melanaphis sacchari
Gene Symbol: -
Assembly: GCA_002803265.2
Location: NW:6388770-6418184[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0086 0.62 10.0 0.4 1 23 234 257 234 257 0.97

2 9 0.0027 0.2 11.6 5.9 1 23 295 317 295 317 0.97

3 9 0.98 72 3.6 1.1 3 23 340 361 336 361 0.92

4 9 0.034 2.5 8.2 8.2 1 23 368 391 368 391 0.96

5 9 0.72 52 4.0 0.1 3 20 398 415 396 417 0.91

6 9 4.2e-07 3.1e-05 23.6 0.3 1 23 517 540 517 540 0.95

7 9 0.33 24 5.1 0.3 2 20 739 757 739 759 0.92

8 9 0.041 3 7.9 1.0 1 21 1384 1404 1384 1407 0.88

9 9 0.00014 0.01 15.7 0.3 1 23 1585 1608 1585 1608 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0086	0.62	10.0	0.4	1	23	234	257	234	257	0.97
2	9	0.0027	0.2	11.6	5.9	1	23	295	317	295	317	0.97
3	9	0.98	72	3.6	1.1	3	23	340	361	336	361	0.92
4	9	0.034	2.5	8.2	8.2	1	23	368	391	368	391	0.96
5	9	0.72	52	4.0	0.1	3	20	398	415	396	417	0.91
6	9	4.2e-07	3.1e-05	23.6	0.3	1	23	517	540	517	540	0.95
7	9	0.33	24	5.1	0.3	2	20	739	757	739	759	0.92
8	9	0.041	3	7.9	1.0	1	21	1384	1404	1384	1407	0.88
9	9	0.00014	0.01	15.7	0.3	1	23	1585	1608	1585	1608	0.97

Sequence Information

Coding Sequence: atgttgGGAAGCAGTTTGCACCATCATAGGAATATGTCATTCCCTCATGGTGgTTCtgtgatacataataatatgcctcCTACCGTTGGTAAAAAAATGAGTGGTGGTCGACTGAATGCCGTGGTGAACAAACTCCATTTAGCAAAACAATGTTCAACTGATAATACCTTTCCAGACATGACTTCTGAAGAAAGCCGTTTatctatattacaaaatttattgaatccTGCACCATCATCAAATTCGGAAAAGAAAAACTTACGTGCTCCTCCAGCGTTGTTTCCACTCACTTCTGAAGTGACAATCCAACGTTACCCTGTTGTTCATCCAATACATGATAGACCATTGGATGTTTTCCAAAGACTTAAACGTCTTGGAACAGACATTGAAATGGAAGAAATCGGAAATGAAACAACACTAAGTCTTATACCAGTTTCATCATCTCAAAATGCTTCTGTTTCATGCATTccaacaaataatttcaaaactaacTCTCCTGCTACCAGTCTCATAGTTCTGCCAAAAACCAATGTGttcaataatagaaaaataccaGAACCTTCTGTTGTTCTTGAAATGAAATTAACTCCAAAACCAAAAGctcaaaatatatgttgtaatGGAAAAACAgacctaaaaaattatgttttttcgaTTGACCAGTCACAAAtaagtataacaaataatggtcaaaaattatactcaTGTAATGTATGTTCAGGCATTTATCAACGAAGAGGTGCTCTAAAGAAACACTATTTAAAGGCACATATTAACTATCATTTTTTGACATCTCGTGACTTGCAAATAGCTGGTTTTAAAGGCGAAAGACTTGAAAAAATGATAGAAAAGTGGAAGAATACAAAAGGTCATGTAGGCTACTACCATtgtcataaatgttttatatcatttagtaCAGCCATTGATTTACGACATCATGTGATGAATCATCCTCCTACTTTACAATCTAATGCTTTGAAAAAACTACCTGATATTGTTACTAAAGTTTGTGAACTATGtttatattgtgataaaaaaattgaaaatgaagaAGATCGAAAAAGCCATTTGTCCAAGATGCACCCACCCAAAAGAAGATGTCATATATGTACATACTGTCAACTtaacttttttgatttatatacattacacaaGCATATGTGTACCACTCATGAAGATATGTATTATGGCTGTGCAGAATGTAAAGAACGATTTATTTCTAGAGAATTAGCTAAAAACCATAAATctatttgtttgaataatttatgtataaaattagaatctgataatgtaaaaaaagagCATTTGAAAGAAGAACCtgcaaaaattgaaatactagAATTGAAAAAAGATGAaccaataaatgttaatattaaaaacgaattatcagacgaaaaactaaataaagaagaatttaaaaaaattgaagaaccAAAAAAAGAGGAACTCAAGAAAAATGAAGAACCAAAACTAgaagaatcaaaaaaaaatgaagaccCAATTAGAGAAGATGTAAAAAAGAAAGAAGAATCCACCAAAAGCTATCCATTTTACTGTCCAGACTGTAAAAAAGGATTTACTCAACAACCAAACTTAGCACGACACATGAGTTTAGGTCATGGCAAAAAGTTAgagtataaaaaatctaaaaagttattacagccttcaaataaaataatgttgtcCAAAAAACTTGTGAAAACTCaagaaaaagaattaaaagacGAGATTCAAGATTTATCAGCTAAAGGAActcaatatgtttttttgaataataaaaatgaactagTTACTAAACAAGGTGTACCGTTTGATGTCTCTTATATGAATCTTGAGATTCAAAGCAGGATCAGACGTATGGTACCATCATTGCATCCTAGTTCATCGCCAATAGAAGATGATATGAGTTCATTAGAGGTCGATGCAGCTTCTTCGTATGGTTTTCCAAGTTCCCAtgatgatgaaaggaaaaaaattgaaggaTTCAGCGGAGAATGGTTATATCCACGTAGTTATATTTGTTCTGCTTGTCCAGCTACATGTTCTAATATTTgggatattttttatcataagtgGAATGTACATCCTAATGTACTTTGCCATCATTATGACATACCAATAGATCAACTTCCATCTCAGAAATggCGACCTGAAAGAAATTTGAGCAGAATAGGATTGTTGTCTGAATGTGAGGAACAACAAACCAGTTTACCACAGTGTACAAAGTGTGGTAAAATGGAAAACGATATTGCTCAGCTTCATAGACATTTGTTAGATTGTGGTGGTGATACTGAGTGGCTCAAAACAATGATTCATACAACTAAGTCCcctaatagtaaaaaatctaGaaAAAATTGGCGGCCTTTTAATTTCCGAAGACGTAAAAATGGTAGAGCTAGACATGGTCTTAAACGAACTCCACCTACTCCACCTTTACCAGTTGTAAAAACTAAACCTGGAGATGctgAAAGTGTTAGTCGTATGATTGCAGATTTACCTCCTAAAAGAGTTACAAGACGTTTAGTATTTGAGGCTCCTAATGGGAATAATCAAGCAACAATAAATAgcAAGTCTGTATGCTCAAAGgttCCTATTGATATGAGCAGCTGTAATCCAACTGTTTCAAGTTCAACTACATTATTTAGTAAGAAAGTTAAAAAGCCATTGCCAGTTATAACTGAAACTGCTATGCTTATTTCTGAAGCGCCAGATTTCTTACGTAGCCTTAACATCATGCGTGCTCCAGTGAAGTCAGCTGAACATGGACACTCTAGCAATAAAACTGAAACTGAAGAAATAATTGCTGCCATGAAAGAAACTTTGATGGCTTCTCCAGCACCCATCCCTGTTATATTACCAAAGAAACGTAAAAGaccaatttatgatttaaaacaattagctGAGAAAATTGCCAAGCATGACCACAATAAAATTCTTGACCCAAAAGTTGATGAAGATCATGATAATACAGAAAAATCTATTCCTATTCCTGTggcagtaaaaaataaaggcAAAAAATTGATGAATGAAATAGAGGTTGGATTGATAAAGCAAAATAGGTTACGGAGGAAGAGAGAAATTCCATCTGTACCTGAAAAGGTAGTCCCAGTTccatcaaaaaaattgaaaattgaaaatgtagaaaatagCACAAAGAATGTAGTAGAATCCATTCCAGTTATTAAAGCCAAAAAACAGGTTACAACAAAGAAAACACCTAAAGTCCTGAAAAAAAAGACAATTGATGAAAattttgtttctaaaataCAAACCCGTAATAggaagaaaaattttattgaggAATCAATGTCCAATGAGATATTACTTTCAGGTAAAGATGATTCTTTAGGAAACAATAATGAATCATCTAATAGTTTTGTTGATTTAGAGTCTAGTCAAGAAGTCTCTTCATCTGAGGTTCctgcaaaacaaaaaacagtTAAAGTGAATCCTTTTAAACCAAAAGCTAGAAACAGAAGAAAACCAGGAGTTTTTTTTGGGTCAAGAAAACGAAAGCGTAATTTAAAGactgataataaaaaacaacagcCTACTTCAAGTAAAGTTGACGATACACCtttattattaccaaaatTAGAATGTActgattcaaatatattagtttcgGACTCGATTGATAAAGTTGTACAACCagaaatcataaaaactaataataccaCACAAAAGTTATCTCAGGAATTGAAAAAATCTGTTGAAAATGAATCCACAATAGTGACTgttaaagaagaaaataaagCCACAGCTCCAATCAGTACTGATACAACTGAGTTAAAAGAACCAGAAGAAGTAGCAGAACCACGTTGGCATTCACAGTCTGAtggtttttttgatttacctTCTGCTATTAGTTTGGGATCAATATTAAGCTCTGTCAATCAGatattggaAGGTCCTGACTGTAACGTTGCAAATACAGAAGTAAATGATTATTCGTGGACAGAGTTACAACGTGCAATGGGGGCTACTGATGAAGAAATGgctatattacaaaattttggTTCAAACTCATCTGAAGAAGGCCAAAATGTAACTAGTGAAAACTGCTTGGATCTATTAGACATGGACAGTAGAGGAGAAACTAATAGAaatcaagaACAAACAGATACTCAAATTAATAgtgaattaaatttcaaatgcaaAGTATGTGATCAATGTTATAAAGGTGTTGCAGCATTTCGTATTCATTCACTTGATGTTCATAGTATCGAAGATCCAGAATTGGttaatgttataaaatctgATTACCTACTCGTTTGTTGGGTTTGCAAGCTCATAATAGAAGGAGGAGCAGAAGAACTCGACGAGCACATGGCAAAAGACCATGAATTTGATGATGCTCcaaatagTGAAAACGGAAAggagttgaaaaataaaatggttaacAAGTTGGGTGAAATATTGGACCAGGCCTTGAAAAATCTGATTTCTTCTACACAAAAaccttgtgCTGGCAAAACCTGGAGTGGTGGTGCAATAACTTTGTTGGGCAAACTGTGTGCACTACGCAACAATGAAAAAGGCACAACTGTATCAAGTAGTGTGGCCAATTCTGCTCTTGCCAAAGACTTACGCAAAGTAATAGGACGTAACAACAATGGATCTAGTGCCAGAGCTCAGTCTAAAAGATCAAATACAGCTCACGCTCTCCAACTAAATGCGCGTTTGGCTGCATTGTCAGTGGCTGCCAAACGACTAACCCCTTTGGTTCGCGCTGATTGTTCGTCCAACATTTACAAATGTCCTATTTGTGATATTGGGTTTGAAACTACAAGTACTAGAAATAAGCACATCAGTCGAGCACATAATAGCCCACAGAAATCAAACCATGTGGAGACTACTGTTCAACtcgATTCAACTCTACAGTCATTGCAGACAACTGTACTGGAAGAAACACCCGAACCTTCTGACAATGTGCAGCCAATGTTTGCATTGGGTACAATGAACCGTAGAGGACTAAAAAAGTTCAATAGCACTTGCAGTGAAGAAGTGCGAGCGCGTGCAAAACAAGCATTGCGTGACCTAGAAATTAAGTCTAGATTGAAACATTACACATTTTCTGGTGACCATCAACCCTCACCCAATTGA
Protein Sequence: MLGSSLHHHRNMSFPHGGSVIHNNMPPTVGKKMSGGRLNAVVNKLHLAKQCSTDNTFPDMTSEESRLSILQNLLNPAPSSNSEKKNLRAPPALFPLTSEVTIQRYPVVHPIHDRPLDVFQRLKRLGTDIEMEEIGNETTLSLIPVSSSQNASVSCIPTNNFKTNSPATSLIVLPKTNVFNNRKIPEPSVVLEMKLTPKPKAQNICCNGKTDLKNYVFSIDQSQISITNNGQKLYSCNVCSGIYQRRGALKKHYLKAHINYHFLTSRDLQIAGFKGERLEKMIEKWKNTKGHVGYYHCHKCFISFSTAIDLRHHVMNHPPTLQSNALKKLPDIVTKVCELCLYCDKKIENEEDRKSHLSKMHPPKRRCHICTYCQLNFFDLYTLHKHMCTTHEDMYYGCAECKERFISRELAKNHKSICLNNLCIKLESDNVKKEHLKEEPAKIEILELKKDEPINVNIKNELSDEKLNKEEFKKIEEPKKEELKKNEEPKLEESKKNEDPIREDVKKKEESTKSYPFYCPDCKKGFTQQPNLARHMSLGHGKKLEYKKSKKLLQPSNKIMLSKKLVKTQEKELKDEIQDLSAKGTQYVFLNNKNELVTKQGVPFDVSYMNLEIQSRIRRMVPSLHPSSSPIEDDMSSLEVDAASSYGFPSSHDDERKKIEGFSGEWLYPRSYICSACPATCSNIWDIFYHKWNVHPNVLCHHYDIPIDQLPSQKWRPERNLSRIGLLSECEEQQTSLPQCTKCGKMENDIAQLHRHLLDCGGDTEWLKTMIHTTKSPNSKKSRKNWRPFNFRRRKNGRARHGLKRTPPTPPLPVVKTKPGDAESVSRMIADLPPKRVTRRLVFEAPNGNNQATINSKSVCSKVPIDMSSCNPTVSSSTTLFSKKVKKPLPVITETAMLISEAPDFLRSLNIMRAPVKSAEHGHSSNKTETEEIIAAMKETLMASPAPIPVILPKKRKRPIYDLKQLAEKIAKHDHNKILDPKVDEDHDNTEKSIPIPVAVKNKGKKLMNEIEVGLIKQNRLRRKREIPSVPEKVVPVPSKKLKIENVENSTKNVVESIPVIKAKKQVTTKKTPKVLKKKTIDENFVSKIQTRNRKKNFIEESMSNEILLSGKDDSLGNNNESSNSFVDLESSQEVSSSEVPAKQKTVKVNPFKPKARNRRKPGVFFGSRKRKRNLKTDNKKQQPTSSKVDDTPLLLPKLECTDSNILVSDSIDKVVQPEIIKTNNTTQKLSQELKKSVENESTIVTVKEENKATAPISTDTTELKEPEEVAEPRWHSQSDGFFDLPSAISLGSILSSVNQILEGPDCNVANTEVNDYSWTELQRAMGATDEEMAILQNFGSNSSEEGQNVTSENCLDLLDMDSRGETNRNQEQTDTQINSELNFKCKVCDQCYKGVAAFRIHSLDVHSIEDPELVNVIKSDYLLVCWVCKLIIEGGAEELDEHMAKDHEFDDAPNSENGKELKNKMVNKLGEILDQALKNLISSTQKPCAGKTWSGGAITLLGKLCALRNNEKGTTVSSSVANSALAKDLRKVIGRNNNGSSARAQSKRSNTAHALQLNARLAALSVAAKRLTPLVRADCSSNIYKCPICDIGFETTSTRNKHISRAHNSPQKSNHVETTVQLDSTLQSLQTTVLEETPEPSDNVQPMFALGTMNRRGLKKFNSTCSEEVRARAKQALRDLEIKSRLKHYTFSGDHQPSPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00942295;
90% Identity: iTF_01032495;
80% Identity: -