Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000093.1:668256-674150[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 3.7 3.3e+02 2.6 2.0 1 20 340 359 340 361 0.90

2 10 0.055 5 8.4 1.2 2 23 390 412 389 412 0.95

3 10 0.069 6.3 8.0 2.5 1 23 435 457 435 457 0.97

4 10 0.00032 0.029 15.4 0.4 1 23 461 484 461 484 0.97

5 10 0.0098 0.89 10.7 2.1 1 23 489 512 489 512 0.94

6 10 0.0092 0.84 10.8 1.3 2 23 519 541 518 541 0.92

7 10 8e-06 0.00073 20.4 1.3 1 23 548 571 548 571 0.98

8 10 0.00077 0.07 14.2 2.1 2 23 578 599 577 599 0.97

9 10 4.3e-07 3.9e-05 24.5 1.4 1 23 605 627 605 627 0.99

10 10 2.4e-05 0.0021 19.0 2.6 1 23 633 655 633 656 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	3.7	3.3e+02	2.6	2.0	1	20	340	359	340	361	0.90
2	10	0.055	5	8.4	1.2	2	23	390	412	389	412	0.95
3	10	0.069	6.3	8.0	2.5	1	23	435	457	435	457	0.97
4	10	0.00032	0.029	15.4	0.4	1	23	461	484	461	484	0.97
5	10	0.0098	0.89	10.7	2.1	1	23	489	512	489	512	0.94
6	10	0.0092	0.84	10.8	1.3	2	23	519	541	518	541	0.92
7	10	8e-06	0.00073	20.4	1.3	1	23	548	571	548	571	0.98
8	10	0.00077	0.07	14.2	2.1	2	23	578	599	577	599	0.97
9	10	4.3e-07	3.9e-05	24.5	1.4	1	23	605	627	605	627	0.99
10	10	2.4e-05	0.0021	19.0	2.6	1	23	633	655	633	656	0.96

Sequence Information

Coding Sequence: ATGAACGGAAATGCCACAAATTGGGGTAGCTATGGCCAGTGCAGATTTTGTAAGTCAGATGGCCATCATCGCTACATAACGAAAGAATATAAATTCCAGGGTGTTAGCGAAGTATATTACGATTTGATTCAAGAATGTTTTAATTTATACCTGTCTACCAGTGCTAGGATGAGCTCCCTGATATGTAACTCTTGTGTAGACCGGCTACGGGAGTCTATGAACTTCCGTAAGCTGGTGCTAGCATCTGAGACCCAGCTCATTGATGTCCTTGATGAGAAGAACTCCATCTTCTTGAGCATGGAAGAACCAGCTCCTGATGTCTCGATGGAGATAAAGTCAGAACCGCCAACGGTGGTTAAGAAGGAGTCTGATGATGAAGCGGATGGCGATGATGATTGGCACGAGCCCGCCACCGACACCAACGACGCCGACGATAATGACGAATACGATGAAGAGGGTAAGAGGTACCACGACATGGGTAATTTAGCTGAGCGACCTCGCAGTGATCGTCCAACTGTGCTGACTGCTGCCCAGAAGCGCTATATCAAATTGTTGACTGCCCGTGACCCAACACAGTTGCAGAGATGCGGGCTGCAACTGGACGTGAAGTTAGCACTCAGACGATTCGGAATTGCTTACACCAGGTTGGTTTACAAACGAGGAGGTCCTGGAGGAGGTCACGGCAACGACAGCGATACAGATTATGCTACGCCCCTTATCAAAGTGCAAGCGGCGATGACCGACGAGGAGAGGTTGCTAGCGCGTTTCCCGAAGCTACCACGCTTGCCAACACGGCGCGAGCTGCGCTTCATGTGCAGGGAGTTCGCGATACAGCTGGACAACTTGCGAGGTAGAACAATAAAGGCGCACACCATACAAAGCATGTTCACGGAAGGATACACCAACGCGATGGGTTCCAGGATCTATATAACGGAGAAGATAGCCCACACCACCAACGTCATCACCATTCTAGAGAATTCCAATGCTACCGCCTTCCAGTCCAAAACCCGATCGGGCTTCCCGTGCCTGTACTGCAGGAAGATATGCGAGACCTTCGAGATACTGCGACATCATCAGGACAGCGACGGATGTAAGACGAGCTTGAAGAAGCTATTGAAGAAGTTCACCGCTGACTGCCTGGTTGTCTACGTTTACGTCCAGAATCTCAAGTGCACGCTGTGCCATCAAAACATACCGAATCTTAACGAGCTAAAGACCCATTTGACAAGAGTTCACAACAAGGAAATGCATTTAGACTTCGGTGATAGGGTGCTTCCGTTCAAGATGTCTCCGTCGAATGAGTTTGAGTGTCAATGCTGTGGGTGTAACTTTGAGACGTTTGGAGCCATCGAAAGGCACATGAATGTGCATTACAGGAACTTTGTCTGCGATCAATGCGGCGCTGGATACGTCACGAAGCAACGTCTGAAGGTGCACATGAAGTATACCCATGAGACGGGACGGTTTCCATGTGAGAGTTGCAAGAAGGTGTACGACACGAGGCATAAATACAGATCTCACGTTGATTCAGTGCACAAGATGCTTAAGAAGAATAAATGCCCGAAATGTCCGGAGAGGTTCGCTGACTTCTTCAATAAACACAAGCATATGGTTGAAGCGCACGGATTGGCCCCCCTCGTGTACAAATGCAATGTGTGCGACTCGGTGTTCAGACGACGGTATGGTCTGTCACTTCACATGAAACGGATGCATCTGGATGTCAGAGACGTTCAATGTCAGATCTGTTCGTACAAGTGTTACACGAATACAGAGCTAAAGATTCACATGGCAAAGCACAGCACGGAGAAGACTTACGAATGTACGGTCTGCAAAAAATCGTACGCCAGGAACAAGACGTTGAAAGAACATATGAGAATACATAACAATGATAGGCGGTACTCCTGTGTTGTGTGTGGACAGGCGTTTGTGCAAAACTGCAGTCTCAAGGGACATATGAAGACGCATCATCTCGACTATATCAATGTGTTGCATTGA
Protein Sequence: MNGNATNWGSYGQCRFCKSDGHHRYITKEYKFQGVSEVYYDLIQECFNLYLSTSARMSSLICNSCVDRLRESMNFRKLVLASETQLIDVLDEKNSIFLSMEEPAPDVSMEIKSEPPTVVKKESDDEADGDDDWHEPATDTNDADDNDEYDEEGKRYHDMGNLAERPRSDRPTVLTAAQKRYIKLLTARDPTQLQRCGLQLDVKLALRRFGIAYTRLVYKRGGPGGGHGNDSDTDYATPLIKVQAAMTDEERLLARFPKLPRLPTRRELRFMCREFAIQLDNLRGRTIKAHTIQSMFTEGYTNAMGSRIYITEKIAHTTNVITILENSNATAFQSKTRSGFPCLYCRKICETFEILRHHQDSDGCKTSLKKLLKKFTADCLVVYVYVQNLKCTLCHQNIPNLNELKTHLTRVHNKEMHLDFGDRVLPFKMSPSNEFECQCCGCNFETFGAIERHMNVHYRNFVCDQCGAGYVTKQRLKVHMKYTHETGRFPCESCKKVYDTRHKYRSHVDSVHKMLKKNKCPKCPERFADFFNKHKHMVEAHGLAPLVYKCNVCDSVFRRRYGLSLHMKRMHLDVRDVQCQICSYKCYTNTELKIHMAKHSTEKTYECTVCKKSYARNKTLKEHMRIHNNDRRYSCVVCGQAFVQNCSLKGHMKTHHLDYINVLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01439336;
90% Identity: -
80% Identity: -