Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000003.1:4877033-4884563[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0005 0.045 14.8 0.4 1 23 302 325 302 325 0.95

2 12 0.076 6.9 7.9 1.7 1 19 341 359 341 363 0.92

3 12 6.1e-05 0.0055 17.7 3.9 2 23 369 390 368 390 0.96

4 12 0.00022 0.02 15.9 1.5 1 23 394 417 394 417 0.93

5 12 2.6 2.4e+02 3.1 2.2 1 23 420 442 420 442 0.97

6 12 0.00015 0.014 16.4 0.4 2 23 526 547 526 547 0.95

7 12 0.31 28 6.0 0.3 3 23 568 589 567 589 0.95

8 12 8.7e-07 7.9e-05 23.5 4.1 1 23 595 617 595 617 0.98

9 12 0.00047 0.043 14.9 2.5 1 23 622 644 622 644 0.98

10 12 0.0048 0.44 11.7 2.5 2 21 651 670 650 673 0.93

11 12 0.66 60 5.0 1.7 1 19 681 699 681 704 0.87

12 12 0.017 1.6 10.0 1.1 3 19 713 729 711 734 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0005	0.045	14.8	0.4	1	23	302	325	302	325	0.95
2	12	0.076	6.9	7.9	1.7	1	19	341	359	341	363	0.92
3	12	6.1e-05	0.0055	17.7	3.9	2	23	369	390	368	390	0.96
4	12	0.00022	0.02	15.9	1.5	1	23	394	417	394	417	0.93
5	12	2.6	2.4e+02	3.1	2.2	1	23	420	442	420	442	0.97
6	12	0.00015	0.014	16.4	0.4	2	23	526	547	526	547	0.95
7	12	0.31	28	6.0	0.3	3	23	568	589	567	589	0.95
8	12	8.7e-07	7.9e-05	23.5	4.1	1	23	595	617	595	617	0.98
9	12	0.00047	0.043	14.9	2.5	1	23	622	644	622	644	0.98
10	12	0.0048	0.44	11.7	2.5	2	21	651	670	650	673	0.93
11	12	0.66	60	5.0	1.7	1	19	681	699	681	704	0.87
12	12	0.017	1.6	10.0	1.1	3	19	713	729	711	734	0.89

Sequence Information

Coding Sequence: ATGGAAAGTGATGCCCTTACGTCGATCACTGATGGCTCATACCCTATGCTTTTCATACCTAAAGCGTGCACCACCTTGGAAACCAACTGTGAAGATTCTGACAACGTTTTTATCGATTTAACCATTACATCCCCAGACACAGAAGGAAATGAAGCTTGTATATACTCTGGATTTTGCAACATCAAGTTGATAGACAACTGTGATACTGTACCAGATCAAGGTTTTAATGCATCCTCGAATGGAAATAACAAAGATCAGAATTCAGTTTTGGATAATGGGACTATATATCCACCATACAGCCAATCCCAAGTGTGGATAGACCCGGCAAGAAGTCCATACATCTATAACAGCTGTGACACAGCCGAGTCACAGGAACGGTACTCAGTCTACCACCAGTCTCACTCCAGTCACATAACAGTGGAACAACACAATACATACATTACTCAAAACGTTTACAACTGTAAAGAAGATTCCATTCGTTATTCACCAGTTGATGACTTTGAGCATAAAAAGTTTAGGAAGATTCAGAACGATACAAGCAATCAGAATAGTTTGGCAGATCAAATTTTATATGAAGACGATGAGTTTGAGTGTGGTGTTTTCCTGTCTAAGCTTCCAGAGGAGATCTGGAATGAGAATGAGACTCGGGCCAGGGAGGAGATGAAGTATGTGGGCATGCAGAGTGAAAATGATGCTCTAAAACAACTCATGTCATCAGATATACAATCACTGTCCAAGCAACAGAAGACAATCCTTTTTCTGGGTCACGATTCACATTTTGGACAAACTATTCAGAAGATTGCTATAAATGATCCATACTTGGAATGTGTTCGTCCAGATCGATGTGAAGATGATCATGAAGTTGTAATTGGACAGAAAGTAACAAAACCTAATCAAAAGAAATACCAATGCGACAAATGCAAGCAAATATTTGACCAAATAGCAGAGTTCAAGCAACACATGATTGGCAATCACAAGAGCCCGAAGATTCCAGGGATGGCGGGCCACAGTGAAGTTAAATTCATGTGTCTAGAATGCGGGAAGAACCTTAAAAACCAGGAGAAGTTTGAGATGCACTGCCTAGGACACGGTGATCCGGACTTAGAATGTAACAAGTGCCATAAAGTATTTGCATCCAAATTCACCCTGCGCACACACAAAAAGATACATCAAAGAAAACACCCTTGTAAGTACTGTTCGAAAACATACTCCAACTTCGAGGATTTGCAGAGTCATGCTGCGAAAATTCACTTCATGTTTATGTGTCATCTGTGTGCCTTTACAGCGGATACCTTCAACGTTTTAAGAGATCACAGGAAAACCCACACGGAGCTGGTTCAAGAATCGAGTGATACGGAATTCAACGTGTCCATAGGAGTTGATTTGATCAGCGAAAATGGCACCTTGTCTCCGATTCCTCAAAACTCTGAACGTGAGATCATTGAACATGATGATATAGGGCTGGACAAGCAGGATGAGATCGCAAGAGCAGACTCCATCATAGCAAAAGTAGTGTCTAACAAGATGTTTCTTTTACATTCCAAGAAGTCGAAACGTGACAAGAAGTTCAGAAACTCTTGCGACGTTTGCTTGAAGACTTTTGACCGGGTCTCGGATCTTAAACGACATCTCATAGAGCACGTCATCCGTAGCACTCTTGCCAAGAATCCAGTCAACAATCATGGGGCTCTGAACATCCTCTGCGAGGTGTGCCAATTGGAAACCTTCACAAAGATAGATAAATATAAAGCTCATTTGCGCGAACACGCTAAACTAACCCTATATAAGTGTACCTTCTGCGATAAATCCTTTAGCGATTCTAGCAATTTTTCTAAGCACAAAAAGATACATGGCTCGACGTATTTCCAGTGCGACCTTTGCCAGCGGAAATTCAACTCTAAGAAGATGATAACACAGCACATGGAATACCACAATAAGAATGCGCCGATACCGTGCTACTATTGTGATAAAATATTCCATTTTGAATCGATGCTGAATAAACATATTAAATGTGCTCATACACGAGAGATCTTCGCTAGATTTCGTTGCAGATTCTGCCAGAAATATTTCAAGAGCTTAAAAGAGAAATGGGACCACGAGTGGACTGTGCATAATGTTAGAAAAATTATTATTGATTGTATGATTTGTGGCGCCAAATACAGAAAGTATTCTGAATTAAAACGTCATTGCAGTAGCGTCCACGAAATGGACATACCGCCAGCGAAGAATTTATTCAAAAAACGAAAGTTTCCGTAA
Protein Sequence: MESDALTSITDGSYPMLFIPKACTTLETNCEDSDNVFIDLTITSPDTEGNEACIYSGFCNIKLIDNCDTVPDQGFNASSNGNNKDQNSVLDNGTIYPPYSQSQVWIDPARSPYIYNSCDTAESQERYSVYHQSHSSHITVEQHNTYITQNVYNCKEDSIRYSPVDDFEHKKFRKIQNDTSNQNSLADQILYEDDEFECGVFLSKLPEEIWNENETRAREEMKYVGMQSENDALKQLMSSDIQSLSKQQKTILFLGHDSHFGQTIQKIAINDPYLECVRPDRCEDDHEVVIGQKVTKPNQKKYQCDKCKQIFDQIAEFKQHMIGNHKSPKIPGMAGHSEVKFMCLECGKNLKNQEKFEMHCLGHGDPDLECNKCHKVFASKFTLRTHKKIHQRKHPCKYCSKTYSNFEDLQSHAAKIHFMFMCHLCAFTADTFNVLRDHRKTHTELVQESSDTEFNVSIGVDLISENGTLSPIPQNSEREIIEHDDIGLDKQDEIARADSIIAKVVSNKMFLLHSKKSKRDKKFRNSCDVCLKTFDRVSDLKRHLIEHVIRSTLAKNPVNNHGALNILCEVCQLETFTKIDKYKAHLREHAKLTLYKCTFCDKSFSDSSNFSKHKKIHGSTYFQCDLCQRKFNSKKMITQHMEYHNKNAPIPCYYCDKIFHFESMLNKHIKCAHTREIFARFRCRFCQKYFKSLKEKWDHEWTVHNVRKIIIDCMICGAKYRKYSELKRHCSSVHEMDIPPAKNLFKKRKFP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01082774;
90% Identity: iTF_00970690;
80% Identity: iTF_00970690;