Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000097.1:107840-116685[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 7.3e-05 0.0066 17.4 4.4 1 23 45 67 45 67 0.98

2 12 0.00027 0.025 15.6 1.6 1 23 74 97 74 97 0.92

3 12 0.0012 0.11 13.6 0.1 2 23 106 128 105 128 0.94

4 12 0.0028 0.26 12.4 0.3 3 23 136 156 134 156 0.96

5 12 8e-05 0.0073 17.3 1.1 1 23 162 186 162 186 0.96

6 12 5.2e-06 0.00048 21.0 3.6 1 23 192 214 192 214 0.97

7 12 0.00024 0.022 15.8 1.4 2 23 222 244 221 244 0.95

8 12 0.046 4.2 8.6 0.0 1 23 251 273 251 273 0.97

9 12 0.0034 0.31 12.2 0.1 2 20 280 298 279 299 0.95

10 12 0.73 67 4.8 4.5 1 21 885 905 885 907 0.90

11 12 7.7 7e+02 1.6 0.8 2 23 918 938 917 938 0.75

12 12 0.7 63 4.9 6.0 1 23 1068 1090 1068 1090 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	7.3e-05	0.0066	17.4	4.4	1	23	45	67	45	67	0.98
2	12	0.00027	0.025	15.6	1.6	1	23	74	97	74	97	0.92
3	12	0.0012	0.11	13.6	0.1	2	23	106	128	105	128	0.94
4	12	0.0028	0.26	12.4	0.3	3	23	136	156	134	156	0.96
5	12	8e-05	0.0073	17.3	1.1	1	23	162	186	162	186	0.96
6	12	5.2e-06	0.00048	21.0	3.6	1	23	192	214	192	214	0.97
7	12	0.00024	0.022	15.8	1.4	2	23	222	244	221	244	0.95
8	12	0.046	4.2	8.6	0.0	1	23	251	273	251	273	0.97
9	12	0.0034	0.31	12.2	0.1	2	20	280	298	279	299	0.95
10	12	0.73	67	4.8	4.5	1	21	885	905	885	907	0.90
11	12	7.7	7e+02	1.6	0.8	2	23	918	938	917	938	0.75
12	12	0.7	63	4.9	6.0	1	23	1068	1090	1068	1090	0.96

Sequence Information

Coding Sequence: ATGACGTTCTTTATTGCAATCGAAGTTAACGCTTCTTTAAGTCGCATAACTTCAAAATTTCTCAAGACCTCGACCGACTGTCCCGATTCAGATCCTGTCCCGTTAATTTCGGTCGTTGCAGATCTGAAGCCTTTTAAGTGCCAGTACTGCGAATACGCATGCAGGGACAGCTCGACGCTGCGCCGGCATCAAGAGCGGCACATGGGCGTCGTGACGCGATACCACTGCAACATATGCGATAGACGATTCTCCAAGAAGCAGCTGTTGCAATACCACGTTGCCGAAGTCCATATGAACATGAATCTCAAGAAGATACCGTGCGAGCAGTGCGATCTGATGTTCAGAACGAAGAAACTGCTTAGTATACATGTCGAAGTGAGACACAATAGAAAGTTTGCGACCAACTGCGAGATCTGTGGACTGAGGATAGCCAACAAATACAATATGAACTCGCATTTAATGTCTCACGTGAACGTCAGGCCTTATAAATGTGGGTTTAGTGGATGCGATAAGCGATACAAGGATCGGAGTTCTTTACAAAAGCATTCGATAATACACTATCCCGAGAAGCAATTTCCATGTAAGATTTGTGGGAAGAAGTTCACGAGGAAGGAAAGACTGAGAAAGCATAAGAAACAACACGTACCTAGAATTAAAAATGTGCAGTGCGATTACTGTGGCGTGTGCTTCTACAACAAAAATTATTTAGCAGTACATATTTTTAAGAAGCATTCGCGTAGAAAAAAAAAGTTTATATGTGATTTATGCGACTTTGAGAGCGGGAACAAGCCGGGTCTTATCAAACATATCAAGGGGCATAACATGAGATTGGATAAGGAGTGTCCAATGTGTAACAAGAAATATAAAGACGAGAATTGGCTGAAAATTCATCTCTGGCAAGCGCATAAAGTTATGGAATCTAATGGAACACCAACATTTAAAACTGATGTTAAAGTTGAACCGCTAGATGTAGACGGAACGCCTGAGTTTGAGCTGTTTGAAATTGAAAAGGAGGAGATACTTGAAGAATTACATTCAATCAATAAAAATACAAATACAGAACAAAATAATGTAATAGAAAAAGACACAGAAGAATATAACGTAATTCAAGAAGAAAATAAAAATAATATTTTAACAACAACTTGTGAACACTTAAAAGATGATGACAGTTCAATACATAGAGAATCCTCTCAAACGAATTCAGCAGAAAATAATGATATACAGCAGTTAGAATACTCTAGTGTACATTTACAAAATGGTGATGATCTCGTAAGTTCACGTCAAAAATGTGCAAACGAAAACTTAACAGATGGACGTGTTTCTGTGGATAATGTAGCAAATGATAAGGAACAACAATCTAAAGTGCAATCTGTAGAACTTTTAGTAAAAAATGCATTAAATGAAATATGTATACCACATTCGAATTGTAGTCAAATAGAGTACGATAATATATTAAGTGATTCTAAAGATGTTATAGAAAAAGAAGAGAATAGTCTCCAAACACCACAATATCTAAATTCTACAAAAGAAATGTATCAAAATGATAGCCCAACACTGAATACAAACGAACAGTATTCTCAAAAACCACGAGACAGTTGCAAACTAATACATAATCTAAAGGAAATTCAACCAAAAATTTACAAAGTTGGCAGCTGTAAAGAAAAAAGTCTAGCATATATTAAAGCAAAACTTAAAGATCAAAAGAAGAAAAAAGATAAGAAAAAATCAATAACCGGTGATTTAAATAATAAATCAAGTAGTTCAAAACGAAAAAGTCTGGCACATATTAAAGCAGCACTTTTAAATAAAAAACAATTTGATATTAATAATAGAACTGATTCCAAGAATCTGTCAGAATCTGAAGGGCTAACATATTCTAAAGCGGTACTCTCAGAAGACATCAGTCGGTGTAAGTCTCAGAGGAAGAAGGAACCAGCAGAGAAGAACTTTGATGACTTCTATATAGAGCACATTCAAAGGCAGGAGAAACCAAGTAACAAATTACTCGAAATAGACAAAGACTCGGAATCATATGCTAAAAATTGCGTAGATAAGCTTTTGGAAAAATATAGAAATAATAATGAAGTTAAATTGATCGAGAAAACGAGACAGGAATATAATGAAAGGATAAGAAAAGCCAGAAAAATACTGCCAGCAAAGGTTTCGATAAAGTATTTCGACAAAATGAGCCAAAATAATTTTACAGTTAAAACTAGCTGTAGTAATGAAGATAGTCGAGACGACAAAATTAATAATGAGGGAGAAAAAGAGTGTAAAGAGTGTAAAAGTTTGGAAACTGCAAAAAAGGGAATAAATTATGATAATAGATTTATTAATCAAGATATATGTGAAAACACTAATAATCTGAATGAATCTATTAATACAAAGCGTGGAGAAAATATAAATATTAACCTTGATGACGGAAAAACGATAAAAACTCATTCGCAATCATATTCAAACAAAGAATGCGATAATGATAGTGAACAACCTCAAAATAATGATGGAATGGTAAATGTAGAAGAAGAGACAGAGACAAATATAATTCAATTGTGTGCTGATTTAAGTAATACGAAACGTTTTAATGGTGACAAAGTTTCTGATAACAATAGAATTACAAATGTTAAAGAGTGTAGGAAAATAAAGCTTAATACACATCAATGTTATGTATGTTTCAAGCTCTTTGCATCCAAAGAAGAATTATTAAATCACTGCAAAGATCATTTCGAGGTTTGCAACTCGACCATTCTGAAGAAATGTCCTCTCTGCGATTTTGCCACGAATTTAAATATTGTTCATCATATGAGAGTAGAACATGACGTTGAAATAACTATACCCAGCACTAAAATAATTGATAAAGAATCAGAAAATGGACCTAGGTACTGTTATAAGGTCAACAGTGCAACGATCAGCGATATAGATGTGATACCGAGTGTTAAACATTTGAATAAACAAGCATATATGGCTATAGATAAGAAAAGACGAAAGCTTAAAGATACAGGAATCGCGAAAACTAGGCTGGTTAAAAAAGGAAAAGAATGGATAGTTGATAGACAGACTACGAAAATCGATAACGTTGATAAATTTATTTTACCACGGTTTGACACCGACGAAATCCTATCAGTCAAAATAGATTCAAACGATTACTTGACCAGGATGAAGAAACTGTATCGGTTAGCAAAGAAACATAAGAAACAAATGCTGTTCCCGTGCGAAAGTTGCGACAAGATCTGTCATACGTTGTCGGCTTTGAAATTGCACTGTCGCAGACATGATCCAAAATCCAAACCGTTTAGAAAGAAGGTTTGGAAGCATAAAATGAAGGATTTAATACAGCCCACGAACAAAAGAGTTACGGATATCGATTATGGCATGAAAAAGTATTCGCGAGTTGTTGAAATCGATGGAAACAGTGCTCCAAATAACGCAATTAATGGTAACCGGTACAAGAAGCCTAAACCTGTCGTGAACAAACATAAATGCGACCCAGAACTTATTAAGTTTTATGAAAATAACATCAAAGGCGGTGATATAGAATTTTGGCAATTTTTAAAAATTTTTAATAAAATGTCCCGAGAAAATATCAATGATTTTGCCGATCTAAACGATAGACCAGAATTTGGGATACATTTAAATGAAACTAATGCGGTCACTAGGATAGAAGGTAGTTCTAAGACTAATAATAATAAAAGAGAAAATAATTCCAATATTCATGAAAAACTTGATAGTAATAAGAACATGGTGGAATATGGCGCAAAACATGCGTCTAAAATAATTAGTAAGAATAGATTCGTAAGAATAATACGGATTAGTAAAAGGGATCATCAGAAAAGGAATGATTTAAAGCAAAAACTTAGAGAGAAGATAGCTAAAGACAGTCCATAG
Protein Sequence: MTFFIAIEVNASLSRITSKFLKTSTDCPDSDPVPLISVVADLKPFKCQYCEYACRDSSTLRRHQERHMGVVTRYHCNICDRRFSKKQLLQYHVAEVHMNMNLKKIPCEQCDLMFRTKKLLSIHVEVRHNRKFATNCEICGLRIANKYNMNSHLMSHVNVRPYKCGFSGCDKRYKDRSSLQKHSIIHYPEKQFPCKICGKKFTRKERLRKHKKQHVPRIKNVQCDYCGVCFYNKNYLAVHIFKKHSRRKKKFICDLCDFESGNKPGLIKHIKGHNMRLDKECPMCNKKYKDENWLKIHLWQAHKVMESNGTPTFKTDVKVEPLDVDGTPEFELFEIEKEEILEELHSINKNTNTEQNNVIEKDTEEYNVIQEENKNNILTTTCEHLKDDDSSIHRESSQTNSAENNDIQQLEYSSVHLQNGDDLVSSRQKCANENLTDGRVSVDNVANDKEQQSKVQSVELLVKNALNEICIPHSNCSQIEYDNILSDSKDVIEKEENSLQTPQYLNSTKEMYQNDSPTLNTNEQYSQKPRDSCKLIHNLKEIQPKIYKVGSCKEKSLAYIKAKLKDQKKKKDKKKSITGDLNNKSSSSKRKSLAHIKAALLNKKQFDINNRTDSKNLSESEGLTYSKAVLSEDISRCKSQRKKEPAEKNFDDFYIEHIQRQEKPSNKLLEIDKDSESYAKNCVDKLLEKYRNNNEVKLIEKTRQEYNERIRKARKILPAKVSIKYFDKMSQNNFTVKTSCSNEDSRDDKINNEGEKECKECKSLETAKKGINYDNRFINQDICENTNNLNESINTKRGENININLDDGKTIKTHSQSYSNKECDNDSEQPQNNDGMVNVEEETETNIIQLCADLSNTKRFNGDKVSDNNRITNVKECRKIKLNTHQCYVCFKLFASKEELLNHCKDHFEVCNSTILKKCPLCDFATNLNIVHHMRVEHDVEITIPSTKIIDKESENGPRYCYKVNSATISDIDVIPSVKHLNKQAYMAIDKKRRKLKDTGIAKTRLVKKGKEWIVDRQTTKIDNVDKFILPRFDTDEILSVKIDSNDYLTRMKKLYRLAKKHKKQMLFPCESCDKICHTLSALKLHCRRHDPKSKPFRKKVWKHKMKDLIQPTNKRVTDIDYGMKKYSRVVEIDGNSAPNNAINGNRYKKPKPVVNKHKCDPELIKFYENNIKGGDIEFWQFLKIFNKMSRENINDFADLNDRPEFGIHLNETNAVTRIEGSSKTNNNKRENNSNIHEKLDSNKNMVEYGAKHASKIISKNRFVRIIRISKRDHQKRNDLKQKLREKIAKDSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00970663;
90% Identity: iTF_00970663;
80% Identity: -