Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000093.1:720269-726533[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0018 0.16 13.1 5.0 1 23 253 275 253 275 0.98

2 10 6.9 6.3e+02 1.8 0.0 3 23 305 326 303 326 0.89

3 10 0.0023 0.21 12.7 0.3 3 23 349 369 347 369 0.91

4 10 1.4e-05 0.0013 19.7 2.0 1 23 373 395 373 395 0.98

5 10 0.0013 0.12 13.5 1.3 1 23 404 427 404 427 0.93

6 10 0.5 45 5.4 1.8 1 23 433 456 433 456 0.94

7 10 6.7e-06 0.00061 20.7 1.0 1 23 462 485 462 485 0.98

8 10 8.1e-05 0.0074 17.3 1.3 1 23 491 513 491 513 0.98

9 10 4.3e-07 3.9e-05 24.5 1.2 1 23 519 541 519 541 0.98

10 10 0.00013 0.012 16.7 2.2 1 23 547 570 547 570 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0018	0.16	13.1	5.0	1	23	253	275	253	275	0.98
2	10	6.9	6.3e+02	1.8	0.0	3	23	305	326	303	326	0.89
3	10	0.0023	0.21	12.7	0.3	3	23	349	369	347	369	0.91
4	10	1.4e-05	0.0013	19.7	2.0	1	23	373	395	373	395	0.98
5	10	0.0013	0.12	13.5	1.3	1	23	404	427	404	427	0.93
6	10	0.5	45	5.4	1.8	1	23	433	456	433	456	0.94
7	10	6.7e-06	0.00061	20.7	1.0	1	23	462	485	462	485	0.98
8	10	8.1e-05	0.0074	17.3	1.3	1	23	491	513	491	513	0.98
9	10	4.3e-07	3.9e-05	24.5	1.2	1	23	519	541	519	541	0.98
10	10	0.00013	0.012	16.7	2.2	1	23	547	570	547	570	0.98

Sequence Information

Coding Sequence: ATGAATACAAGTAGTAAAAAAGGTCCCGTTTTCGAGTCAGGCGAGTGCAGATGTTGTGGAGCAACAAAAAGGTGCCGATTACTTAACGTGGAATACGAATTTATGGGCCAAAAGGAAGTATATTCCGAAATGTTCGTCGATTGTTTTGGTTTGATGCTATCTCACTTGGATGGTGAAGAACCAGAGCGTATGATATGTGCCACTTGCGTTACTAGACTTCGAGAGGCGAGAGACTTTCGAAATCAGGTGCTGCGCTGTGAGGAGAGGTTGCTACGAGCCAACATTCAACTCGTCGGCGAAAACAATATCGATCCCAACGTCAAAGTTGAGATAGAAATAGGCATTAAGGAAGAGACCGAGATGGATAACAATAATTATGAAGAGCAAAAAGATATGGACAGTCAGATAGCTGATGAGCACATTGAGAACAGGAGCAGGACTCAGTCACCGGAACCCATAAGACGAAAATCTCCAAGAAAAAAGATGGGGAAGACCTCAAAAAAGCAAAGCAAATTAACTGAAAGTAAACGAAATAGTAAATCTTCGATTAAAGAACACATTAGGGCTAGGAAAGAGATGCTGATCAGTATGAAGAGGACAAAGGAGAAATTGAAAAAGGCTTTGAGAAAAGAAAAAACATCAGAAATAGTGCGACTTGAAGGCAACAGGATACAAAAGAGCACTAAAGCCTTCTCCAACACTGTGACAATAGTAGAAAATTCCTACGTATGTCCCTTCCAGTCTATCTTCAACGATTTCTACTGTGATTACTGCAGGGAGAAATTCACAGATCACCAGAAACTCAGAGAGCATTACTTGAGACACGATCCGACCACTTTTAAGGATGCTATTATGGATAGCATGCGAAGACTTGGTCGAAAGAAAACTCAGCTAGACGTTCAACGGATAGATTGTAGGCTGTGCCCTGAGCCGATAAACGATATAGAATCATTTAAAGACCACCTGACAGCTGTGCATGGCAAAAATTTGTATCCCGTTGAAAATGAATTCCTACAATTCAAAGTCATACCAAATAAATTAGAGTGCATTGAATGTGGTCAATCGTTCACTTTGTTCCAGTCACTTAAAAAACACATGGCTGAGCACTTTGGTACGTATACATGTGATATTTGTGGGACACACTTCTTCAATGAAAGCTATCTTCTCGCTCACCAAAAGAACCATGACACAAATAGCAAACCGGAGTTGTATACTTGTGAGGAATGCGGAAGGTCATTCAAGCTGAAATATAGCAGGGATATGCATGTCACCACTCAGCACAAGAAAGAGGCAGCGTTCCAATGTATAAAGTGTGATGGTATGTTCTTTTCAAGTAGACAACGGTTTAAGCATATGATGGAGATGCATGGAGAACGGTCAACGTTTCAGTGCAGCCAGTGTGACCGAGTGTATGACAGCAGAAAGACGTTGCTGGACCATATGAGGCGGATCCATGTGAAAATGCTGAAGCACAAATGTAGTATGTGCGAACGAAGATTTTATCTCCCGTCTATGTTAAAAGACCATATGGCTATTCACACGGGTGAGAAGAATTTTAAATGTGATTACTGCGGGAAAAGTTATCCGAGGCTGAAATCGCTTAAAGTACATTTGCAATCGCACGCAGCCATTAAGAAATATAAATGCGCGCACTGCAGCGCATCGTACGGGCAGAATGTCAGTTTGAAAAATCACATGAAGCGCACACACCAACTTGGTTTGGAAGAAGGTGTATAA
Protein Sequence: MNTSSKKGPVFESGECRCCGATKRCRLLNVEYEFMGQKEVYSEMFVDCFGLMLSHLDGEEPERMICATCVTRLREARDFRNQVLRCEERLLRANIQLVGENNIDPNVKVEIEIGIKEETEMDNNNYEEQKDMDSQIADEHIENRSRTQSPEPIRRKSPRKKMGKTSKKQSKLTESKRNSKSSIKEHIRARKEMLISMKRTKEKLKKALRKEKTSEIVRLEGNRIQKSTKAFSNTVTIVENSYVCPFQSIFNDFYCDYCREKFTDHQKLREHYLRHDPTTFKDAIMDSMRRLGRKKTQLDVQRIDCRLCPEPINDIESFKDHLTAVHGKNLYPVENEFLQFKVIPNKLECIECGQSFTLFQSLKKHMAEHFGTYTCDICGTHFFNESYLLAHQKNHDTNSKPELYTCEECGRSFKLKYSRDMHVTTQHKKEAAFQCIKCDGMFFSSRQRFKHMMEMHGERSTFQCSQCDRVYDSRKTLLDHMRRIHVKMLKHKCSMCERRFYLPSMLKDHMAIHTGEKNFKCDYCGKSYPRLKSLKVHLQSHAAIKKYKCAHCSASYGQNVSLKNHMKRTHQLGLEEGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00288270;
90% Identity: iTF_00795934;
80% Identity: iTF_00970653;