Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000093.1:767144-770503[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00013 0.012 16.6 2.5 1 23 242 264 242 264 0.98

2 10 0.22 20 6.4 0.3 3 23 291 311 289 311 0.95

3 10 0.00021 0.02 15.9 0.8 2 23 332 353 331 353 0.95

4 10 0.086 7.8 7.8 1.9 2 23 358 379 357 379 0.96

5 10 1.5e-05 0.0014 19.5 1.8 1 23 386 409 386 409 0.96

6 10 0.026 2.4 9.4 1.2 1 23 415 438 415 438 0.95

7 10 5.9e-05 0.0054 17.7 3.0 1 23 444 467 444 467 0.97

8 10 0.0035 0.32 12.1 4.6 1 23 473 495 473 495 0.98

9 10 8.5e-08 7.7e-06 26.7 0.7 1 23 501 523 501 523 0.98

10 10 8.2e-07 7.5e-05 23.6 1.5 1 23 529 552 529 552 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00013	0.012	16.6	2.5	1	23	242	264	242	264	0.98
2	10	0.22	20	6.4	0.3	3	23	291	311	289	311	0.95
3	10	0.00021	0.02	15.9	0.8	2	23	332	353	331	353	0.95
4	10	0.086	7.8	7.8	1.9	2	23	358	379	357	379	0.96
5	10	1.5e-05	0.0014	19.5	1.8	1	23	386	409	386	409	0.96
6	10	0.026	2.4	9.4	1.2	1	23	415	438	415	438	0.95
7	10	5.9e-05	0.0054	17.7	3.0	1	23	444	467	444	467	0.97
8	10	0.0035	0.32	12.1	4.6	1	23	473	495	473	495	0.98
9	10	8.5e-08	7.7e-06	26.7	0.7	1	23	501	523	501	523	0.98
10	10	8.2e-07	7.5e-05	23.6	1.5	1	23	529	552	529	552	0.98

Sequence Information

Coding Sequence: ATGACTAATAATAAAAAAGGTCCCGTGTTTGACGCCGGTTCGTGCCGGTGCTGCGGCGAAACGAAGAGATGTCGGCTACTGACCGTGGAGTATGATTGGATGGGGCAGAAGGAAATCTATTCTGATATGTTTCTTGATTGCTTTGGCTTAGTGCTTTCTCATCTGGATGGCGAAGAAAAGGAGCGTTTGATCTGTGCAACATGTGTGTCGAGACTTCGTGAGGCCATCAGTTTTTACCGTCAGGTCCTGAAGTGTGAAGAGAAACTTCTGCAGACCAGTATACAACTACATACTGATAATGCAGATTTATTTAGTGTAAAAGCTGAAGAGAGTGTTAAGGATGAGAAGCAGGAAGCTACTATTGAGATAGAACTTGTTAACAACGATGGCGTGGACCATTTGGATTATGATTCAGATATTCCAGAACTAAAAGGAGAAGTAAAACAAAGCATTAAACCAGGAAAAAGGCGCCGACGGAAAAGGGGTTTGAAGGGTAAAAAGAAAGTTCATGATGAAGATATAATCGCGAAGAACCAGATGCTGCAAGATATGGAGAAGATGTATGATAGGTTGACGGAAATACAGACGATTGAATCAGGAAAGCGACATCTCCCAAAGTTATCGGATTCGAGAGAGAACGATAAAAGCCTAAAGTCCATATATAATCTAAACGTCCTGGTCGAATATTCTTACGCGTGTCCTTTTGACACCTCCTTCAGCGATTATTTTTGCAGCTACTGTAGACAGAAATTCACTGACCCTAACAAGCTGAGAGACCATACCCTCACACACAATCCCAAAGACTTTAGTGTAGTTTTGAAGAACACTAGCATGACTAAGAAACTGCAGGTAGATATCTACCGAATAGATTGCCGGTTGTGTTCAGAGAGCATCAATGACGTGGAAACCTTCAAGAAACATATAACGAGCCATGGTAAAGAAGTTCATTCAGTACCAGACGAGTTCCTTAAATTTCGACTGACTTACAATCTTAGTTGCATGGAGTGTGGTGCGAGTTTTAGCTTCTTCCATGCATTAAAGAAACATATGGCGGAACATTTCGGCACCTGCATCTGTGATGTCTGCGGTGCTCATTATTTTGAAGAGCGAATGTTACTGCTTCATCAGAAAACCCATCAGCGTGTTGAGGAGTCGTACAGTTGCAAGGATTGCGGCAAGAGTTTTAAGTCTAAGTACACGAGATATATCCACATAGCGAGGATGCACAAGAAGGAAGCTGCGTACCAGTGCAATAAATGTGATGAATTGTTTTTCTCATATATGCTCAGATACAGACACATGATGGAAGCCCATGGGGAGGAGAGGATGTTCCAATGTGACCATTGCGACCGTGTATATGACAGCAGGAAGTCCCTTCGAGAACACAACAGAAGACTACATCTGAGGATCATGAAGCATCAATGTGATCTATGCGACAAGCGGTTTTACTTGCCCTGCAGACTGCGAGAGCACATGTCCAGCCACACCGGTGAGAGGAACTTCAGGTGTGAGTACTGCGGTAAGAGCTTTCCAAGGCTCAGAGGTCTGAAGGTCCACATGCAGTCACACAGCAATGATAAGAAGTACAAATGTGTGATGTGCAATGCATCATTCACACAGAATGTCAATTTGAAAAATCATATGAAACGGCAGCATCTCAGCTTGGTGGCAACTCAGATGGATGAGAGTTATCATGAGTAG
Protein Sequence: MTNNKKGPVFDAGSCRCCGETKRCRLLTVEYDWMGQKEIYSDMFLDCFGLVLSHLDGEEKERLICATCVSRLREAISFYRQVLKCEEKLLQTSIQLHTDNADLFSVKAEESVKDEKQEATIEIELVNNDGVDHLDYDSDIPELKGEVKQSIKPGKRRRRKRGLKGKKKVHDEDIIAKNQMLQDMEKMYDRLTEIQTIESGKRHLPKLSDSRENDKSLKSIYNLNVLVEYSYACPFDTSFSDYFCSYCRQKFTDPNKLRDHTLTHNPKDFSVVLKNTSMTKKLQVDIYRIDCRLCSESINDVETFKKHITSHGKEVHSVPDEFLKFRLTYNLSCMECGASFSFFHALKKHMAEHFGTCICDVCGAHYFEERMLLLHQKTHQRVEESYSCKDCGKSFKSKYTRYIHIARMHKKEAAYQCNKCDELFFSYMLRYRHMMEAHGEERMFQCDHCDRVYDSRKSLREHNRRLHLRIMKHQCDLCDKRFYLPCRLREHMSSHTGERNFRCEYCGKSFPRLRGLKVHMQSHSNDKKYKCVMCNASFTQNVNLKNHMKRQHLSLVATQMDESYHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00795961;
90% Identity: iTF_01438294;
80% Identity: iTF_00970642;